RU2008148977A - Применение комбинированных препаратов, содержащих противогрибковые средства - Google Patents
Применение комбинированных препаратов, содержащих противогрибковые средства Download PDFInfo
- Publication number
- RU2008148977A RU2008148977A RU2008148977/15A RU2008148977A RU2008148977A RU 2008148977 A RU2008148977 A RU 2008148977A RU 2008148977/15 A RU2008148977/15 A RU 2008148977/15A RU 2008148977 A RU2008148977 A RU 2008148977A RU 2008148977 A RU2008148977 A RU 2008148977A
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- RU
- Russia
- Prior art keywords
- use according
- antifungal agent
- candidiasis
- cox1
- thrush
- Prior art date
Links
- 230000001716 anti-fugal effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 206010007134 Candida infections Diseases 0.000 claims abstract 6
- 229940121375 antifungal agent Drugs 0.000 claims abstract 6
- 239000003429 antifungal agent Substances 0.000 claims abstract 6
- 201000003984 candidiasis Diseases 0.000 claims abstract 6
- 239000003112 inhibitor Substances 0.000 claims abstract 6
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims abstract 6
- 201000004624 Dermatitis Diseases 0.000 claims abstract 4
- 101000919849 Homo sapiens Cytochrome c oxidase subunit 1 Proteins 0.000 claims abstract 4
- 101000605122 Homo sapiens Prostaglandin G/H synthase 1 Proteins 0.000 claims abstract 4
- 208000007027 Oral Candidiasis Diseases 0.000 claims abstract 4
- 102100038277 Prostaglandin G/H synthase 1 Human genes 0.000 claims abstract 4
- 241000287411 Turdidae Species 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 4
- 210000002889 endothelial cell Anatomy 0.000 claims abstract 4
- 210000002919 epithelial cell Anatomy 0.000 claims abstract 4
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims abstract 4
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 claims abstract 3
- 229960001259 diclofenac Drugs 0.000 claims abstract 3
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims abstract 3
- 229960001680 ibuprofen Drugs 0.000 claims abstract 3
- 229960002202 lornoxicam Drugs 0.000 claims abstract 3
- OXROWJKCGCOJDO-JLHYYAGUSA-N lornoxicam Chemical compound O=C1C=2SC(Cl)=CC=2S(=O)(=O)N(C)\C1=C(\O)NC1=CC=CC=N1 OXROWJKCGCOJDO-JLHYYAGUSA-N 0.000 claims abstract 3
- MPIPASJGOJYODL-SFHVURJKSA-N (R)-isoconazole Chemical compound ClC1=CC(Cl)=CC=C1[C@@H](OCC=1C(=CC=CC=1Cl)Cl)CN1C=NC=C1 MPIPASJGOJYODL-SFHVURJKSA-N 0.000 claims abstract 2
- ZCJYUTQZBAIHBS-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)benzyl]oxy}ethyl]imidazole Chemical compound ClC1=CC(Cl)=CC=C1C(OCC=1C=CC(SC=2C=CC=CC=2)=CC=1)CN1C=NC=C1 ZCJYUTQZBAIHBS-UHFFFAOYSA-N 0.000 claims abstract 2
- OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 claims abstract 2
- LEZWWPYKPKIXLL-UHFFFAOYSA-N 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole Chemical compound C1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 LEZWWPYKPKIXLL-UHFFFAOYSA-N 0.000 claims abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims abstract 2
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims abstract 2
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 claims abstract 2
- KLSJWNVTNUYHDU-UHFFFAOYSA-N Amitrole Chemical group NC1=NC=NN1 KLSJWNVTNUYHDU-UHFFFAOYSA-N 0.000 claims abstract 2
- APKFDSVGJQXUKY-KKGHZKTASA-N Amphotericin-B Natural products O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-KKGHZKTASA-N 0.000 claims abstract 2
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 claims abstract 2
- 239000005528 B01AC05 - Ticlopidine Substances 0.000 claims abstract 2
- 241000222122 Candida albicans Species 0.000 claims abstract 2
- 101000725401 Homo sapiens Cytochrome c oxidase subunit 2 Proteins 0.000 claims abstract 2
- 101000605127 Homo sapiens Prostaglandin G/H synthase 2 Proteins 0.000 claims abstract 2
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims abstract 2
- 206010050346 Oropharyngeal candidiasis Diseases 0.000 claims abstract 2
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 claims abstract 2
- 229940123185 Squalene epoxidase inhibitor Drugs 0.000 claims abstract 2
- 201000007096 Vulvovaginal Candidiasis Diseases 0.000 claims abstract 2
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 claims abstract 2
- 229960003942 amphotericin b Drugs 0.000 claims abstract 2
- 208000010668 atopic eczema Diseases 0.000 claims abstract 2
- 229960002206 bifonazole Drugs 0.000 claims abstract 2
- 229960002962 butenafine Drugs 0.000 claims abstract 2
- ABJKWBDEJIDSJZ-UHFFFAOYSA-N butenafine Chemical compound C=1C=CC2=CC=CC=C2C=1CN(C)CC1=CC=C(C(C)(C)C)C=C1 ABJKWBDEJIDSJZ-UHFFFAOYSA-N 0.000 claims abstract 2
- JYIKNQVWKBUSNH-QWDBRQCVSA-N caspofungin Chemical compound C1([C@H](O)[C@@H](O)[C@H]2C(=O)N[C@H](C(=O)N3CC[C@H](O)[C@H]3C(=O)N[C@H](NCCN)[C@H](O)CC(C(N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N2)[C@@H](C)O)=O)NC(=O)CCCCCCCCC(C)CC(C)CC)[C@H](O)CCN)=CC=C(O)C=C1 JYIKNQVWKBUSNH-QWDBRQCVSA-N 0.000 claims abstract 2
- ARUGKOZUKWAXDS-SEWALLKFSA-N cicaprost Chemical compound C1\C(=C/COCC(O)=O)C[C@@H]2[C@@H](C#C[C@@H](O)[C@@H](C)CC#CCC)[C@H](O)C[C@@H]21 ARUGKOZUKWAXDS-SEWALLKFSA-N 0.000 claims abstract 2
- 229950000634 cicaprost Drugs 0.000 claims abstract 2
- SCKYRAXSEDYPSA-UHFFFAOYSA-N ciclopirox Chemical compound ON1C(=O)C=C(C)C=C1C1CCCCC1 SCKYRAXSEDYPSA-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960003009 clopidogrel Drugs 0.000 claims abstract 2
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical compound C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 claims abstract 2
- 229960004022 clotrimazole Drugs 0.000 claims abstract 2
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960003913 econazole Drugs 0.000 claims abstract 2
- 230000003511 endothelial effect Effects 0.000 claims abstract 2
- 229960001123 epoprostenol Drugs 0.000 claims abstract 2
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 claims abstract 2
- 229960001274 fenticonazole Drugs 0.000 claims abstract 2
- 229960004884 fluconazole Drugs 0.000 claims abstract 2
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960004413 flucytosine Drugs 0.000 claims abstract 2
- XRECTZIEBJDKEO-UHFFFAOYSA-N flucytosine Chemical compound NC1=NC(=O)NC=C1F XRECTZIEBJDKEO-UHFFFAOYSA-N 0.000 claims abstract 2
- LPEPZBJOKDYZAD-UHFFFAOYSA-N flufenamic acid Chemical compound OC(=O)C1=CC=CC=C1NC1=CC=CC(C(F)(F)F)=C1 LPEPZBJOKDYZAD-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960004369 flufenamic acid Drugs 0.000 claims abstract 2
- 229960000905 indomethacin Drugs 0.000 claims abstract 2
- 230000005764 inhibitory process Effects 0.000 claims abstract 2
- 229960004849 isoconazole Drugs 0.000 claims abstract 2
- 229960004130 itraconazole Drugs 0.000 claims abstract 2
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960000991 ketoprofen Drugs 0.000 claims abstract 2
- 229960003464 mefenamic acid Drugs 0.000 claims abstract 2
- HYYBABOKPJLUIN-UHFFFAOYSA-N mefenamic acid Chemical compound CC1=CC=CC(NC=2C(=CC=CC=2)C(O)=O)=C1C HYYBABOKPJLUIN-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960002509 miconazole Drugs 0.000 claims abstract 2
- 210000000214 mouth Anatomy 0.000 claims abstract 2
- 229960003255 natamycin Drugs 0.000 claims abstract 2
- NCXMLFZGDNKEPB-FFPOYIOWSA-N natamycin Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C[C@@H](C)OC(=O)/C=C/[C@H]2O[C@@H]2C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 NCXMLFZGDNKEPB-FFPOYIOWSA-N 0.000 claims abstract 2
- 235000010298 natamycin Nutrition 0.000 claims abstract 2
- 239000004311 natamycin Substances 0.000 claims abstract 2
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims abstract 2
- 229960000988 nystatin Drugs 0.000 claims abstract 2
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 claims abstract 2
- 229960004031 omoconazole Drugs 0.000 claims abstract 2
- JMFOSJNGKJCTMJ-ZHZULCJRSA-N omoconazole Chemical compound C1=CN=CN1C(/C)=C(C=1C(=CC(Cl)=CC=1)Cl)\OCCOC1=CC=C(Cl)C=C1 JMFOSJNGKJCTMJ-ZHZULCJRSA-N 0.000 claims abstract 2
- 229960003483 oxiconazole Drugs 0.000 claims abstract 2
- QRJJEGAJXVEBNE-MOHJPFBDSA-N oxiconazole Chemical compound ClC1=CC(Cl)=CC=C1CO\N=C(C=1C(=CC(Cl)=CC=1)Cl)\CN1C=NC=C1 QRJJEGAJXVEBNE-MOHJPFBDSA-N 0.000 claims abstract 2
- 150000004291 polyenes Chemical class 0.000 claims abstract 2
- 150000003815 prostacyclins Chemical class 0.000 claims abstract 2
- 229960002722 terbinafine Drugs 0.000 claims abstract 2
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims abstract 2
- 229960005001 ticlopidine Drugs 0.000 claims abstract 2
- PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 claims abstract 2
- 239000000126 substance Substances 0.000 claims 2
- 239000000443 aerosol Substances 0.000 claims 1
- 239000007936 buccal or sublingual tablet Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 229960002702 piroxicam Drugs 0.000 claims 1
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- -1 tincture Substances 0.000 claims 1
- 229940098465 tincture Drugs 0.000 claims 1
- 239000006213 vaginal ring Substances 0.000 claims 1
- 229940044953 vaginal ring Drugs 0.000 claims 1
- 239000006216 vaginal suppository Substances 0.000 claims 1
- 239000000003 vaginal tablet Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA826/2006 | 2006-05-12 | ||
| AT8262006 | 2006-05-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008148977A true RU2008148977A (ru) | 2010-06-20 |
Family
ID=37903545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008148977/15A RU2008148977A (ru) | 2006-05-12 | 2007-05-10 | Применение комбинированных препаратов, содержащих противогрибковые средства |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8552042B2 (https=) |
| EP (2) | EP2018164B1 (https=) |
| JP (1) | JP2009536926A (https=) |
| CN (1) | CN101484162A (https=) |
| AU (1) | AU2007250502B2 (https=) |
| CA (1) | CA2651726C (https=) |
| CY (1) | CY1119094T1 (https=) |
| DK (1) | DK2018164T3 (https=) |
| ES (1) | ES2627268T3 (https=) |
| HR (1) | HRP20170793T1 (https=) |
| HU (1) | HUE033499T2 (https=) |
| LT (1) | LT2018164T (https=) |
| NO (2) | NO342103B1 (https=) |
| PL (1) | PL2018164T3 (https=) |
| PT (1) | PT2018164T (https=) |
| RS (1) | RS56044B1 (https=) |
| RU (1) | RU2008148977A (https=) |
| SI (1) | SI2018164T1 (https=) |
| WO (1) | WO2007131253A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI23311A (sl) * | 2010-03-19 | 2011-09-30 | Kemijski inštitut | Farmacevtska kombinacija acetilsalicilne kisline in protiglivne substance za uničevanje ali inhibicijo rasti in replikacije gliv |
| CN102210649A (zh) * | 2010-04-09 | 2011-10-12 | 上海医药科技发展有限公司 | 一种两性霉素b乳膏及其制备方法 |
| FR2993179B1 (fr) * | 2012-07-13 | 2016-01-08 | Lesaffre & Cie | Levure saccharomyces cerevisiae pour prevenir et/ou traiter les mycoses vaginales |
| CN103044408A (zh) * | 2013-01-21 | 2013-04-17 | 万礼 | 在治疗恶性肿瘤时应用的伊曲康唑或其盐及其组合物 |
| US8883747B1 (en) * | 2013-10-09 | 2014-11-11 | Craig W. Carver | Topical antifungal compositions and methods of use thereof |
| BR112017014295B1 (pt) | 2015-01-13 | 2023-04-25 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A | Composição farmacêutica. |
| CN104920360B (zh) * | 2015-06-18 | 2017-04-12 | 青岛农业大学 | 丁苯羟酸在制备用于防治由植物病原菌引起的植物病害的杀菌剂中的用途 |
| EP3482744A1 (de) | 2017-11-14 | 2019-05-15 | ProFem GmbH | Emulsionen zur topischen behandlung urogenitaler und dermaler infektionen |
| BR112020009454A2 (pt) | 2017-11-14 | 2020-10-13 | Profem Gmbh | emulsões para o tratamento de infecções da mucosa |
| EP3482743A1 (de) | 2017-11-14 | 2019-05-15 | ProFem GmbH | Emulsionen zur behandlung von scheideninfektionen |
| FR3089788B1 (fr) * | 2018-12-17 | 2020-12-18 | Lesaffre & Cie | Souche de levure Saccharomyces cerevisiae pour le traitement et/ou la prévention de candidoses oropharyngées |
| US20250302821A1 (en) * | 2022-05-12 | 2025-10-02 | St. Jude Children's Research Hospital, Inc. | Synergistic antifungal composition and method |
| WO2024187210A1 (de) | 2023-03-15 | 2024-09-19 | Profem Gmbh | Kombinationsarzneimittel zur behandlung und reduktion der rückfallraten vaginaler mykosen |
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| JPS6471823A (en) * | 1987-09-12 | 1989-03-16 | Rohto Pharma | Sustained remedy for vaginal candidiasis |
| US5087620A (en) * | 1990-05-17 | 1992-02-11 | Bristol-Myers Squibb Co. | Controlled dermal penetration enhancement using imidazoles |
| ES2079994B1 (es) * | 1992-10-07 | 1996-08-01 | Cusi Lab | Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica. |
| EP0735861A1 (en) * | 1993-12-23 | 1996-10-09 | The Procter & Gamble Company | Tissue moisturizing and antimicrobial compositions |
| US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
| US6159977A (en) | 1998-11-16 | 2000-12-12 | Astan, Inc. | Therapeutic anti-fungal nail preparation |
| WO2000048633A1 (en) | 1999-02-19 | 2000-08-24 | Ligocyte Pharmaceuticals, Inc. | Antibodies against hydrophobic proteins that are protective against candidiasis |
| EP1191939B1 (en) * | 1999-03-24 | 2007-10-17 | Zengen, Inc. | Antimicrobial amino acid sequences derived from alpha-melanocyte-stimulating hormone |
| GB0108082D0 (en) | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
| US20030181384A1 (en) * | 2001-09-06 | 2003-09-25 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
| US20040142910A1 (en) * | 2002-10-21 | 2004-07-22 | Aegis Biosciences Llc | Sulfonated styrene copolymers for medical uses |
| WO2004060283A2 (en) * | 2002-12-16 | 2004-07-22 | Nitromed, Inc. | Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use |
| JPWO2005000287A1 (ja) | 2003-06-25 | 2006-10-05 | 久光製薬株式会社 | 水虫治療用外用剤 |
| ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
| WO2005009342A2 (en) * | 2003-07-16 | 2005-02-03 | Pharmacia Corporation | Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith |
| TWI290051B (en) | 2004-05-28 | 2007-11-21 | Schering Corp | Particulate-stabilized injectable pharmaceutical compositions of Posaconazole |
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2007
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- 2007-05-10 PL PL07718439T patent/PL2018164T3/pl unknown
- 2007-05-10 RU RU2008148977/15A patent/RU2008148977A/ru not_active Application Discontinuation
- 2007-05-10 SI SI200731935A patent/SI2018164T1/sl unknown
- 2007-05-10 RS RS20170559A patent/RS56044B1/sr unknown
- 2007-05-10 CN CNA200780025026XA patent/CN101484162A/zh active Pending
- 2007-05-10 DK DK07718439.8T patent/DK2018164T3/en active
- 2007-05-10 ES ES07718439.8T patent/ES2627268T3/es active Active
- 2007-05-10 HU HUE07718439A patent/HUE033499T2/en unknown
- 2007-05-10 CA CA2651726A patent/CA2651726C/en active Active
- 2007-05-10 EP EP17158393.3A patent/EP3192507B1/de active Active
- 2007-05-10 US US12/300,578 patent/US8552042B2/en active Active
- 2007-05-10 JP JP2009508042A patent/JP2009536926A/ja active Pending
- 2007-05-10 HR HRP20170793TT patent/HRP20170793T1/hr unknown
- 2007-05-10 AU AU2007250502A patent/AU2007250502B2/en active Active
- 2007-05-10 LT LTEP07718439.8T patent/LT2018164T/lt unknown
- 2007-05-10 WO PCT/AT2007/000227 patent/WO2007131253A2/de not_active Ceased
- 2007-05-10 PT PT77184398T patent/PT2018164T/pt unknown
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2008
- 2008-12-11 NO NO20085181A patent/NO342103B1/no unknown
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2013
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2017
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2018
- 2018-01-18 NO NO20180083A patent/NO345064B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3192507B1 (de) | 2020-07-08 |
| CA2651726A1 (en) | 2007-11-22 |
| RS56044B1 (sr) | 2017-09-29 |
| HUE033499T2 (en) | 2017-12-28 |
| SI2018164T1 (sl) | 2017-07-31 |
| US20090208558A1 (en) | 2009-08-20 |
| JP2009536926A (ja) | 2009-10-22 |
| WO2007131253A2 (de) | 2007-11-22 |
| AU2007250502B2 (en) | 2013-11-28 |
| AU2007250502A1 (en) | 2007-11-22 |
| DK2018164T3 (en) | 2017-06-12 |
| US8815925B2 (en) | 2014-08-26 |
| NO20085181L (no) | 2009-02-10 |
| PL2018164T3 (pl) | 2017-08-31 |
| CN101484162A (zh) | 2009-07-15 |
| CY1119094T1 (el) | 2018-01-10 |
| LT2018164T (lt) | 2017-07-10 |
| EP3192507A1 (de) | 2017-07-19 |
| ES2627268T3 (es) | 2017-07-27 |
| EP2018164A2 (de) | 2009-01-28 |
| NO20180083A1 (no) | 2009-02-10 |
| PT2018164T (pt) | 2017-06-12 |
| NO342103B1 (no) | 2018-03-26 |
| HRP20170793T1 (hr) | 2017-10-06 |
| NO345064B1 (no) | 2020-09-14 |
| EP2018164B1 (de) | 2017-03-01 |
| CA2651726C (en) | 2015-12-15 |
| WO2007131253A3 (de) | 2008-11-27 |
| US8552042B2 (en) | 2013-10-08 |
| US20140030312A1 (en) | 2014-01-30 |
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