HRP20170793T1 - Uporaba kombiniranih pripravaka koji obuhvaćaju antimikotike - Google Patents
Uporaba kombiniranih pripravaka koji obuhvaćaju antimikotike Download PDFInfo
- Publication number
- HRP20170793T1 HRP20170793T1 HRP20170793TT HRP20170793T HRP20170793T1 HR P20170793 T1 HRP20170793 T1 HR P20170793T1 HR P20170793T T HRP20170793T T HR P20170793TT HR P20170793 T HRP20170793 T HR P20170793T HR P20170793 T1 HRP20170793 T1 HR P20170793T1
- Authority
- HR
- Croatia
- Prior art keywords
- drug
- combined
- vaginal
- cox1
- nsaid
- Prior art date
Links
- 239000003429 antifungal agent Substances 0.000 title claims 3
- 229940121375 antifungal agent Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000003814 drug Substances 0.000 claims 5
- 229940079593 drug Drugs 0.000 claims 4
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 3
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 3
- 201000004624 Dermatitis Diseases 0.000 claims 2
- 206010012444 Dermatitis diaper Diseases 0.000 claims 1
- 208000003105 Diaper Rash Diseases 0.000 claims 1
- 206010017533 Fungal infection Diseases 0.000 claims 1
- 101000919849 Homo sapiens Cytochrome c oxidase subunit 1 Proteins 0.000 claims 1
- 101000725401 Homo sapiens Cytochrome c oxidase subunit 2 Proteins 0.000 claims 1
- 101000605122 Homo sapiens Prostaglandin G/H synthase 1 Proteins 0.000 claims 1
- 101000605127 Homo sapiens Prostaglandin G/H synthase 2 Proteins 0.000 claims 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 1
- 206010050346 Oropharyngeal candidiasis Diseases 0.000 claims 1
- 102100038277 Prostaglandin G/H synthase 1 Human genes 0.000 claims 1
- 102100038280 Prostaglandin G/H synthase 2 Human genes 0.000 claims 1
- 201000007096 Vulvovaginal Candidiasis Diseases 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 229960004022 clotrimazole Drugs 0.000 claims 1
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical group ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 claims 1
- 229960001259 diclofenac Drugs 0.000 claims 1
- 208000024386 fungal infectious disease Diseases 0.000 claims 1
- HYYBABOKPJLUIN-UHFFFAOYSA-N mefenamic acid Chemical compound CC1=CC=CC(NC=2C(=CC=CC=2)C(O)=O)=C1C HYYBABOKPJLUIN-UHFFFAOYSA-N 0.000 claims 1
- 229960003464 mefenamic acid Drugs 0.000 claims 1
- 229960002509 miconazole Drugs 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 229940096978 oral tablet Drugs 0.000 claims 1
- 239000007935 oral tablet Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000006190 sub-lingual tablet Substances 0.000 claims 1
- 229940098466 sublingual tablet Drugs 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 229940044953 vaginal ring Drugs 0.000 claims 1
- 239000006213 vaginal ring Substances 0.000 claims 1
- 229940120293 vaginal suppository Drugs 0.000 claims 1
- 239000006216 vaginal suppository Substances 0.000 claims 1
- 229940044977 vaginal tablet Drugs 0.000 claims 1
- 239000000003 vaginal tablet Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Claims (2)
1. Kombinirani lijek, naznačen time, da obuhvaća sljedeće:
- antimikotičko sredstvo, pri čemu je navedeno antimikotičko sredstvo klotrimazol ili mikonazol, i
- nesteroidni protuupalni lijek (NSAID) koji ima dovoljno COX1-inhibicije, definiran putem izdvajanja spojeva koji imaju omjer COX1/COX2 (IC50, microM) veći od 20, pri čemu navedeni NSAID je diklofenak ili mefenaminska kiselina,
dok je lijek za uporabu u topikalnom liječenju Candida-mikoza koje su odabrane od sljedećih: vulvovaginalne kandidaze, orofaringealne kandidaze (afte u usnoj šupljini), pelenski dermatitis (pelenski osip), intertriginozni ekcem,
pri čemu se navedeni kombinirani lijek pripravlja kao mast, krema, vaginalni supozitorij, vaginalna tableta, oralna tableta ili tableta za pod jezik, prašak ili aerosol.
2. Kombinirani lijek za uporabu prema zahtjevu 1, naznačen time, da se navedeni kombinirani lijek dostavlja na inertnom nosaču, posebno na vaginalnom prstenu, na dijafragmi ili na tamponu.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT8262006 | 2006-05-12 | ||
EP07718439.8A EP2018164B1 (de) | 2006-05-12 | 2007-05-10 | Verwendung von kombinationspräparaten, umfassend antimykotika |
PCT/AT2007/000227 WO2007131253A2 (de) | 2006-05-12 | 2007-05-10 | Verwendung von kombinationspräparaten, umfassend antimykotika |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20170793T1 true HRP20170793T1 (hr) | 2017-10-06 |
Family
ID=37903545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20170793TT HRP20170793T1 (hr) | 2006-05-12 | 2017-05-26 | Uporaba kombiniranih pripravaka koji obuhvaćaju antimikotike |
Country Status (19)
Country | Link |
---|---|
US (2) | US8552042B2 (hr) |
EP (2) | EP3192507B1 (hr) |
JP (1) | JP2009536926A (hr) |
CN (1) | CN101484162A (hr) |
AU (1) | AU2007250502B2 (hr) |
CA (1) | CA2651726C (hr) |
CY (1) | CY1119094T1 (hr) |
DK (1) | DK2018164T3 (hr) |
ES (1) | ES2627268T3 (hr) |
HR (1) | HRP20170793T1 (hr) |
HU (1) | HUE033499T2 (hr) |
LT (1) | LT2018164T (hr) |
NO (2) | NO342103B1 (hr) |
PL (1) | PL2018164T3 (hr) |
PT (1) | PT2018164T (hr) |
RS (1) | RS56044B1 (hr) |
RU (1) | RU2008148977A (hr) |
SI (1) | SI2018164T1 (hr) |
WO (1) | WO2007131253A2 (hr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI23311A (sl) * | 2010-03-19 | 2011-09-30 | Kemijski inštitut | Farmacevtska kombinacija acetilsalicilne kisline in protiglivne substance za uničevanje ali inhibicijo rasti in replikacije gliv |
CN102210649A (zh) * | 2010-04-09 | 2011-10-12 | 上海医药科技发展有限公司 | 一种两性霉素b乳膏及其制备方法 |
FR2993179B1 (fr) * | 2012-07-13 | 2016-01-08 | Lesaffre & Cie | Levure saccharomyces cerevisiae pour prevenir et/ou traiter les mycoses vaginales |
CN103044408A (zh) * | 2013-01-21 | 2013-04-17 | 万礼 | 在治疗恶性肿瘤时应用的伊曲康唑或其盐及其组合物 |
US8883747B1 (en) * | 2013-10-09 | 2014-11-11 | Craig W. Carver | Topical antifungal compositions and methods of use thereof |
CN107106690B (zh) | 2015-01-13 | 2020-11-10 | 方济各安吉利克化学联合股份有限公司 | 用于治疗真菌病的药物组合物 |
CN104920360B (zh) * | 2015-06-18 | 2017-04-12 | 青岛农业大学 | 丁苯羟酸在制备用于防治由植物病原菌引起的植物病害的杀菌剂中的用途 |
EP3482743A1 (de) | 2017-11-14 | 2019-05-15 | ProFem GmbH | Emulsionen zur behandlung von scheideninfektionen |
EP3482744A1 (de) | 2017-11-14 | 2019-05-15 | ProFem GmbH | Emulsionen zur topischen behandlung urogenitaler und dermaler infektionen |
MX2020005056A (es) * | 2017-11-14 | 2020-10-28 | Profem Gmbh | Emulsiones para el tratamiento tópico de infecciones dérmicas y de mucosas. |
FR3089788B1 (fr) * | 2018-12-17 | 2020-12-18 | Lesaffre & Cie | Souche de levure Saccharomyces cerevisiae pour le traitement et/ou la prévention de candidoses oropharyngées |
WO2023220224A1 (en) * | 2022-05-12 | 2023-11-16 | St. Jude Children's Research Hospital, Inc. | Synergistic antifungal composition and method |
WO2024187210A1 (de) | 2023-03-15 | 2024-09-19 | Profem Gmbh | Kombinationsarzneimittel zur behandlung und reduktion der rückfallraten vaginaler mykosen |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6471823A (en) * | 1987-09-12 | 1989-03-16 | Rohto Pharma | Sustained remedy for vaginal candidiasis |
US5087620A (en) * | 1990-05-17 | 1992-02-11 | Bristol-Myers Squibb Co. | Controlled dermal penetration enhancement using imidazoles |
ES2079994B1 (es) * | 1992-10-07 | 1996-08-01 | Cusi Lab | Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica. |
CA2177683C (en) * | 1993-12-23 | 1999-12-28 | George Endel Deckner | Tissue moisturizing and antimicrobial compositions |
US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
US6159977A (en) | 1998-11-16 | 2000-12-12 | Astan, Inc. | Therapeutic anti-fungal nail preparation |
WO2000048633A1 (en) | 1999-02-19 | 2000-08-24 | Ligocyte Pharmaceuticals, Inc. | Antibodies against hydrophobic proteins that are protective against candidiasis |
ATE375801T1 (de) | 1999-03-24 | 2007-11-15 | Zengen Inc | Antimikrobielle aminosäuresequenzen aus alpha- melanocyten-stimulierendem hormon |
GB0108082D0 (en) | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
US20030181384A1 (en) * | 2001-09-06 | 2003-09-25 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
US20040142910A1 (en) * | 2002-10-21 | 2004-07-22 | Aegis Biosciences Llc | Sulfonated styrene copolymers for medical uses |
WO2004060283A2 (en) * | 2002-12-16 | 2004-07-22 | Nitromed, Inc. | Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use |
US20070099932A1 (en) * | 2003-06-25 | 2007-05-03 | Toshihiro Shirouzu | External preparation for athlete's foot treatment |
WO2005009342A2 (en) * | 2003-07-16 | 2005-02-03 | Pharmacia Corporation | Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith |
ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
AR049063A1 (es) * | 2004-05-28 | 2006-06-21 | Schering Corp | Composiciones farmaceuticas inyectables de posaconazol con particulas estabilizadas |
-
2007
- 2007-05-10 PT PT77184398T patent/PT2018164T/pt unknown
- 2007-05-10 JP JP2009508042A patent/JP2009536926A/ja active Pending
- 2007-05-10 CN CNA200780025026XA patent/CN101484162A/zh active Pending
- 2007-05-10 AU AU2007250502A patent/AU2007250502B2/en active Active
- 2007-05-10 EP EP17158393.3A patent/EP3192507B1/de active Active
- 2007-05-10 US US12/300,578 patent/US8552042B2/en active Active
- 2007-05-10 RS RS20170559A patent/RS56044B1/sr unknown
- 2007-05-10 EP EP07718439.8A patent/EP2018164B1/de active Active
- 2007-05-10 ES ES07718439.8T patent/ES2627268T3/es active Active
- 2007-05-10 SI SI200731935A patent/SI2018164T1/sl unknown
- 2007-05-10 WO PCT/AT2007/000227 patent/WO2007131253A2/de active Application Filing
- 2007-05-10 CA CA2651726A patent/CA2651726C/en active Active
- 2007-05-10 RU RU2008148977/15A patent/RU2008148977A/ru not_active Application Discontinuation
- 2007-05-10 LT LTEP07718439.8T patent/LT2018164T/lt unknown
- 2007-05-10 PL PL07718439T patent/PL2018164T3/pl unknown
- 2007-05-10 HU HUE07718439A patent/HUE033499T2/en unknown
- 2007-05-10 DK DK07718439.8T patent/DK2018164T3/en active
-
2008
- 2008-12-11 NO NO20085181A patent/NO342103B1/no unknown
-
2013
- 2013-10-02 US US14/044,532 patent/US8815925B2/en active Active
-
2017
- 2017-05-26 HR HRP20170793TT patent/HRP20170793T1/hr unknown
- 2017-05-30 CY CY20171100556T patent/CY1119094T1/el unknown
-
2018
- 2018-01-18 NO NO20180083A patent/NO345064B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO345064B1 (no) | 2020-09-14 |
NO20180083A1 (no) | 2009-02-10 |
WO2007131253A2 (de) | 2007-11-22 |
EP2018164B1 (de) | 2017-03-01 |
CA2651726C (en) | 2015-12-15 |
WO2007131253A3 (de) | 2008-11-27 |
EP3192507A1 (de) | 2017-07-19 |
HUE033499T2 (en) | 2017-12-28 |
DK2018164T3 (en) | 2017-06-12 |
CY1119094T1 (el) | 2018-01-10 |
EP2018164A2 (de) | 2009-01-28 |
RU2008148977A (ru) | 2010-06-20 |
RS56044B1 (sr) | 2017-09-29 |
US20090208558A1 (en) | 2009-08-20 |
PL2018164T3 (pl) | 2017-08-31 |
JP2009536926A (ja) | 2009-10-22 |
AU2007250502A1 (en) | 2007-11-22 |
LT2018164T (lt) | 2017-07-10 |
US20140030312A1 (en) | 2014-01-30 |
SI2018164T1 (sl) | 2017-07-31 |
US8815925B2 (en) | 2014-08-26 |
NO342103B1 (no) | 2018-03-26 |
US8552042B2 (en) | 2013-10-08 |
ES2627268T3 (es) | 2017-07-27 |
AU2007250502B2 (en) | 2013-11-28 |
PT2018164T (pt) | 2017-06-12 |
EP3192507B1 (de) | 2020-07-08 |
CN101484162A (zh) | 2009-07-15 |
CA2651726A1 (en) | 2007-11-22 |
NO20085181L (no) | 2009-02-10 |
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