RU2007133709A - Производные в-циклодекстрина в качестве антибактериальных агентов - Google Patents
Производные в-циклодекстрина в качестве антибактериальных агентов Download PDFInfo
- Publication number
- RU2007133709A RU2007133709A RU2007133709/04A RU2007133709A RU2007133709A RU 2007133709 A RU2007133709 A RU 2007133709A RU 2007133709/04 A RU2007133709/04 A RU 2007133709/04A RU 2007133709 A RU2007133709 A RU 2007133709A RU 2007133709 A RU2007133709 A RU 2007133709A
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- aralkyl
- aryl
- ness
- aminoalkyl
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title claims 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical class OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims 27
- 125000003710 aryl alkyl group Chemical group 0.000 claims 14
- 125000003118 aryl group Chemical group 0.000 claims 14
- 229910052757 nitrogen Inorganic materials 0.000 claims 14
- 125000000623 heterocyclic group Chemical group 0.000 claims 9
- 241000124008 Mammalia Species 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 8
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 7
- 125000004430 oxygen atom Chemical group O* 0.000 claims 7
- 125000004434 sulfur atom Chemical group 0.000 claims 7
- 241000894006 Bacteria Species 0.000 claims 5
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- 125000005343 heterocyclic alkyl group Chemical group 0.000 claims 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 5
- 229910052760 oxygen Inorganic materials 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- 229910052717 sulfur Inorganic materials 0.000 claims 5
- 208000035143 Bacterial infection Diseases 0.000 claims 4
- 125000004103 aminoalkyl group Chemical group 0.000 claims 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 125000004429 atom Chemical group 0.000 claims 3
- 230000003115 biocidal effect Effects 0.000 claims 3
- -1 (ness.) O-alkyl Chemical group 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000003389 potentiating effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64784105P | 2005-01-28 | 2005-01-28 | |
| US60/647,841 | 2005-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2007133709A true RU2007133709A (ru) | 2009-03-20 |
Family
ID=36777776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007133709/04A RU2007133709A (ru) | 2005-01-28 | 2006-01-27 | Производные в-циклодекстрина в качестве антибактериальных агентов |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7737132B2 (enExample) |
| EP (1) | EP1846006A4 (enExample) |
| JP (1) | JP2008528761A (enExample) |
| KR (1) | KR20070101347A (enExample) |
| CN (1) | CN101151037A (enExample) |
| AU (1) | AU2006211173A1 (enExample) |
| CA (1) | CA2596026A1 (enExample) |
| IL (1) | IL184844A0 (enExample) |
| MX (1) | MX2007010129A (enExample) |
| RU (1) | RU2007133709A (enExample) |
| WO (1) | WO2006083678A2 (enExample) |
| ZA (1) | ZA200706191B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120277184A1 (en) * | 2004-01-29 | 2012-11-01 | Innovative biologics, Inc | Blockers of pore-forming virulence factors and their use as anti-infectives |
| WO2006001844A2 (en) * | 2004-01-29 | 2006-01-05 | Pinnacle Pharmaceuticals | β-CYCLODEXTRIN DERIVATIVES AND THEIR USE AGAINST ANTHRAX LETHAL TOXIN |
| JP5098015B2 (ja) * | 2005-01-13 | 2012-12-12 | 国立大学法人 名古屋工業大学 | 菌体膜傷害性・抗菌性物質とその利用方法 |
| EP1846006A4 (en) * | 2005-01-28 | 2011-04-20 | Pinnacle Pharmaceuticals Inc | BETA-CYCLODEXTRIN DERIVATIVES AS ANTIBACTERIAL AGENTS |
| WO2008105822A2 (en) * | 2006-08-30 | 2008-09-04 | Research Foundation Of The City University Of New York | Antimicrobial compositions |
| WO2009058327A1 (en) * | 2007-10-30 | 2009-05-07 | Pinnacle Pharmaceuticals, Inc. | Cyclodextrin derivatives as potentiators for antibiotics |
| JP5364923B2 (ja) * | 2009-01-28 | 2013-12-11 | 学校法人福岡大学 | 多機能性シクロデキストリン誘導体、その包接化合物およびそれらの製造方法。 |
| GB201114459D0 (en) | 2011-08-22 | 2011-10-05 | Isis Innovation | Anti-bacterial compounds |
| EP2690105A1 (en) * | 2012-07-24 | 2014-01-29 | Centre National De La Recherche Scientifique | Mannose derivatives, a process for preparing the same and their uses as a drug |
| JP6249208B2 (ja) * | 2012-10-31 | 2017-12-20 | 国立大学法人 名古屋工業大学 | 糖誘導体及びそれを用いた抗菌剤 |
| CN103497275B (zh) * | 2013-08-09 | 2015-12-23 | 华北电力大学（保定） | 一种抗菌、抗病毒胍盐星形聚合物及其制备方法和应用 |
| JP6624422B2 (ja) * | 2014-07-25 | 2019-12-25 | 国立大学法人 名古屋工業大学 | 糖誘導体またはその塩、それらを用いた抗菌剤または抗菌活性増強剤、およびこれらを合成する試薬、試薬を用いたこれらの製造方法 |
| CN106734046A (zh) * | 2015-11-20 | 2017-05-31 | 南京科技职业学院 | 一种焦化污泥无害化处理方法 |
| JP6734510B2 (ja) | 2016-09-13 | 2020-08-05 | 国立大学法人 名古屋工業大学 | 糖誘導体またはその塩、それらを用いた抗菌剤または抗菌活性増強剤 |
| WO2018127819A1 (en) | 2017-01-03 | 2018-07-12 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto |
| WO2018178902A1 (en) | 2017-03-28 | 2018-10-04 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto |
| KR101967326B1 (ko) * | 2017-10-30 | 2019-08-13 | 한남대학교 산학협력단 | 양이온성 사이클로덱스트린 유도체 및 이를 이용한 약물전달 시스템 |
| US12460050B2 (en) | 2017-11-15 | 2025-11-04 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto |
| AU2019231712B2 (en) * | 2018-03-06 | 2025-04-10 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto |
| CA3124673A1 (en) | 2018-12-28 | 2020-07-02 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing antibacterial polymers and scaffolds fabricated therefrom and methods pertaining thereto |
| TWI774079B (zh) * | 2020-10-05 | 2022-08-11 | 逢興生物科技股份有限公司 | 環糊精用於製造抑制口腔細菌生長的組合物的用途 |
| CN112516003A (zh) * | 2020-12-18 | 2021-03-19 | 上海杜可生物科技有限公司 | 环糊精用于抑制口腔细菌生长的组合物的用途 |
| US11856953B2 (en) | 2021-03-11 | 2024-01-02 | Nano And Advanced Materials Institute Limited | Launderable bactericidal and virucidal fabric finish |
| CN116284506B (zh) * | 2023-03-22 | 2023-12-08 | 江南大学 | 一种γ-环糊精-香叶醇衍生物及其制备方法与应用 |
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| JPH0375634A (ja) | 1989-08-17 | 1991-03-29 | Agency Of Ind Science & Technol | 光学記憶媒体 |
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| FR2776666B1 (fr) | 1998-03-31 | 2002-09-06 | Commissariat Energie Atomique | Complexes d'inclusion dans des cyclodextrines d'isothiocyanates organiques, en particulier bacteriostatiques, bactericides et/ou fongicides ou de leurs precurseurs naturels, et leur preparation |
| FR2792942B1 (fr) | 1999-04-29 | 2001-06-08 | Commissariat Energie Atomique | Cyclodextrines amphiphiles, leur preparation et leur utilisation pour solubiliser des systemes organises et incorporer des molecules hydrophobes |
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| DE60135540D1 (de) * | 2001-03-27 | 2008-10-09 | Samsung Electronics Co Ltd | noporen |
| US6632748B2 (en) | 2001-03-27 | 2003-10-14 | Samsung Electronics Co., Ltd. | Composition for preparing substances having nano-pores |
| FR2843397B1 (fr) | 2002-08-06 | 2004-10-15 | Chelator | Nouveaux derives de cyclodextrines, leur procede de preparation et leurs applications |
| KR100533538B1 (ko) | 2002-12-03 | 2005-12-05 | 삼성전자주식회사 | 새로운 기공형성물질을 포함하는 다공성 층간 절연막을형성하기 위한 조성물 |
| JP4675233B2 (ja) * | 2003-03-27 | 2011-04-20 | ナノデックス株式会社 | 新規シクロデキストリン誘導体 |
| FR2852959B1 (fr) | 2003-03-28 | 2008-02-15 | Centre Nat Rech Scient | Nouveaux derives de cyclodextrines, leur procede de preparation et leur utilisation notamment pour solubilisation de substances pharmacologiquement actives |
| WO2005011710A1 (en) * | 2003-07-28 | 2005-02-10 | The Board Of Trustees Of The University Of Illinois | Per-6-aminosubstituted-deoxy-cyclodextrins to treat alzheimer’s diseases |
| FR2861396B1 (fr) | 2003-10-24 | 2005-12-16 | Commissariat Energie Atomique | Derives amphiphiles de cyclodextrines,leur procede de preparation et leurs utilisations |
| WO2006001844A2 (en) * | 2004-01-29 | 2006-01-05 | Pinnacle Pharmaceuticals | β-CYCLODEXTRIN DERIVATIVES AND THEIR USE AGAINST ANTHRAX LETHAL TOXIN |
| JP2005290066A (ja) | 2004-03-31 | 2005-10-20 | Nihon Hels Industry Corp | シクロデキストリンポリマーおよびこれを利用した水の汚染度の測定方法 |
| EP1817348B1 (en) | 2004-09-10 | 2011-06-22 | National Center for Scientific Research "Demokritos" Neapoleos & | Per-6-guanidino-, -aminoalkylamino-and -guanidino-alkylamino-cyclodextrins, methods of their synthesis and their use for the compaction of dna and intracellular delivery |
| FR2878853B1 (fr) | 2004-12-07 | 2007-03-16 | Biocydex Soc Par Actions Simpl | Procede d'obtention d'un complexe fluorescent, complexe obtenu et utilisation |
| JP5098015B2 (ja) * | 2005-01-13 | 2012-12-12 | 国立大学法人 名古屋工業大学 | 菌体膜傷害性・抗菌性物質とその利用方法 |
| EP1846006A4 (en) * | 2005-01-28 | 2011-04-20 | Pinnacle Pharmaceuticals Inc | BETA-CYCLODEXTRIN DERIVATIVES AS ANTIBACTERIAL AGENTS |
| WO2007009265A1 (en) | 2005-07-22 | 2007-01-25 | The Governors Of The University Of Alberta Tec Edmonton | NOVEL β-CYCLODEXTRIN-BASED MOLECULES AND DRUG DELIVERY COMPOSITIONS |
-
2006
- 2006-01-27 EP EP06733927A patent/EP1846006A4/en not_active Withdrawn
- 2006-01-27 US US11/342,339 patent/US7737132B2/en not_active Expired - Fee Related
- 2006-01-27 CN CNA2006800101557A patent/CN101151037A/zh active Pending
- 2006-01-27 WO PCT/US2006/002801 patent/WO2006083678A2/en not_active Ceased
- 2006-01-27 MX MX2007010129A patent/MX2007010129A/es unknown
- 2006-01-27 AU AU2006211173A patent/AU2006211173A1/en not_active Abandoned
- 2006-01-27 RU RU2007133709/04A patent/RU2007133709A/ru not_active Application Discontinuation
- 2006-01-27 CA CA002596026A patent/CA2596026A1/en not_active Abandoned
- 2006-01-27 KR KR1020077019399A patent/KR20070101347A/ko not_active Withdrawn
- 2006-01-27 JP JP2007553231A patent/JP2008528761A/ja active Pending
-
2007
- 2007-07-26 ZA ZA200706191A patent/ZA200706191B/xx unknown
- 2007-07-26 IL IL184844A patent/IL184844A0/en unknown
-
2010
- 2010-05-03 US US12/772,740 patent/US20110071108A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN101151037A (zh) | 2008-03-26 |
| ZA200706191B (en) | 2010-05-26 |
| KR20070101347A (ko) | 2007-10-16 |
| IL184844A0 (en) | 2008-06-05 |
| US20110071108A1 (en) | 2011-03-24 |
| JP2008528761A (ja) | 2008-07-31 |
| US7737132B2 (en) | 2010-06-15 |
| EP1846006A4 (en) | 2011-04-20 |
| EP1846006A2 (en) | 2007-10-24 |
| WO2006083678A3 (en) | 2006-12-14 |
| AU2006211173A1 (en) | 2006-08-10 |
| CA2596026A1 (en) | 2006-08-10 |
| MX2007010129A (es) | 2007-11-16 |
| WO2006083678A2 (en) | 2006-08-10 |
| US20060199785A1 (en) | 2006-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20100415 |