RU2006112576A - Получение производных 3-азабицикло [3.1.0] гексана - Google Patents

Получение производных 3-азабицикло [3.1.0] гексана Download PDF

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Publication number
RU2006112576A
RU2006112576A RU2006112576/04A RU2006112576A RU2006112576A RU 2006112576 A RU2006112576 A RU 2006112576A RU 2006112576/04 A RU2006112576/04 A RU 2006112576/04A RU 2006112576 A RU2006112576 A RU 2006112576A RU 2006112576 A RU2006112576 A RU 2006112576A
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RU
Russia
Prior art keywords
alkyl
hydroxy
azabicyclo
exo
hex
Prior art date
Application number
RU2006112576/04A
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English (en)
Russian (ru)
Inventor
Джотам Уодсворт КОЭ (US)
Джотам Уодсворт КОЭ
Стэнтон Фурст МАКХАРДИ (US)
Стэнтон Фурст МАКХАРДИ
Джон Энтони РЭГАН (US)
Джон Энтони РЭГАН
Дерек Лоуренс ТИКНЕР (US)
Дерек Лоуренс ТИКНЕР
Брайан Клемент ВАНДЕРПЛАС (US)
Брайан Клемент ВАНДЕРПЛАС
Original Assignee
Пфайзер Продактс Инк. (Us)
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. (Us), Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк. (Us)
Publication of RU2006112576A publication Critical patent/RU2006112576A/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
RU2006112576/04A 2003-10-16 2004-10-06 Получение производных 3-азабицикло [3.1.0] гексана RU2006112576A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51188903P 2003-10-16 2003-10-16
US60/511,889 2003-10-16

Publications (1)

Publication Number Publication Date
RU2006112576A true RU2006112576A (ru) 2006-08-27

Family

ID=34465290

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006112576/04A RU2006112576A (ru) 2003-10-16 2004-10-06 Получение производных 3-азабицикло [3.1.0] гексана

Country Status (17)

Country Link
US (1) US7129263B2 (enExample)
EP (1) EP1675829A1 (enExample)
JP (1) JP2007508367A (enExample)
KR (1) KR20060096038A (enExample)
CN (1) CN1867548A (enExample)
AR (1) AR046592A1 (enExample)
AU (1) AU2004281229A1 (enExample)
BR (1) BRPI0415459A (enExample)
CA (1) CA2540860A1 (enExample)
CO (1) CO5680416A2 (enExample)
IL (1) IL174596A0 (enExample)
MX (1) MXPA06004278A (enExample)
NO (1) NO20062152L (enExample)
RU (1) RU2006112576A (enExample)
TW (1) TW200524866A (enExample)
WO (1) WO2005037790A1 (enExample)
ZA (1) ZA200601964B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2314289T3 (es) 2002-12-10 2009-03-16 Wyeth Derivados del acido 1h-indol-3-il glioxilico sustituidos con arilo, ariloxi y alquloxi como inhibidores del inhibidor del activador del plasminogeno-1(pai-1).
MXPA06004279A (es) * 2003-10-14 2006-06-28 Pfizer Prod Inc Derivados biciclicos [3.1.0] como inhibidores del transportador de glicina.
WO2008075162A2 (en) * 2006-12-15 2008-06-26 Pfizer Limited Selective mu opioid receptor antagonists for the treatment of female sexual dysfunction
BR112013007566A2 (pt) 2010-09-28 2016-08-02 Panacea Biotec Ltd novos compostos bicíclicos
EP3610890A1 (en) 2012-11-14 2020-02-19 The Johns Hopkins University Methods and compositions for treating schizophrenia
RU2701861C1 (ru) 2013-11-20 2019-10-02 Санва Кагаку Кенкюсо Ко., Лтд. Новое производное 3-азабицикло[3.1.0]гексана и его применение в медицинских целях
CA2985327A1 (en) * 2015-05-20 2016-11-24 Sanwa Kagaku Kenkyusho Co., Ltd. Crystal of salt of 3-azabicyclo[3.1.0]hexane derivative and pharmaceutical use thereof
WO2019173173A1 (en) * 2018-03-05 2019-09-12 E. I. Du Pont De Nemours And Company Process and intermidiates for the preparation of certain mesoionic pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
EP1440059B1 (en) * 2001-10-22 2008-04-16 Pfizer Products Inc. 3-azabicyclo(3.1.0)hexane derivatives as opioid receptor antagonists

Also Published As

Publication number Publication date
US7129263B2 (en) 2006-10-31
TW200524866A (en) 2005-08-01
JP2007508367A (ja) 2007-04-05
ZA200601964B (en) 2007-04-25
IL174596A0 (en) 2006-08-20
AR046592A1 (es) 2005-12-14
MXPA06004278A (es) 2006-06-28
NO20062152L (no) 2006-05-12
CA2540860A1 (en) 2005-04-28
CN1867548A (zh) 2006-11-22
BRPI0415459A (pt) 2006-12-19
WO2005037790A1 (en) 2005-04-28
KR20060096038A (ko) 2006-09-05
US20050113437A1 (en) 2005-05-26
EP1675829A1 (en) 2006-07-05
CO5680416A2 (es) 2006-09-29
AU2004281229A1 (en) 2005-04-28

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Legal Events

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FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20070730