CO5680416A2 - Preparacion de derivados de 3-azabiciclo [3,1,0]hexano - Google Patents

Preparacion de derivados de 3-azabiciclo [3,1,0]hexano

Info

Publication number
CO5680416A2
CO5680416A2 CO06033213A CO06033213A CO5680416A2 CO 5680416 A2 CO5680416 A2 CO 5680416A2 CO 06033213 A CO06033213 A CO 06033213A CO 06033213 A CO06033213 A CO 06033213A CO 5680416 A2 CO5680416 A2 CO 5680416A2
Authority
CO
Colombia
Prior art keywords
alkyl
alkylene
cycloalkyl
compound
formula
Prior art date
Application number
CO06033213A
Other languages
English (en)
Spanish (es)
Inventor
Coe Jotham Wadsworth
Stanton Furst Mchardy
John Anthony Ragan
Derek Lawrence Tickner
Brian Clement Vanderplas
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO5680416A2 publication Critical patent/CO5680416A2/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CO06033213A 2003-10-16 2006-04-05 Preparacion de derivados de 3-azabiciclo [3,1,0]hexano CO5680416A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51188903P 2003-10-16 2003-10-16

Publications (1)

Publication Number Publication Date
CO5680416A2 true CO5680416A2 (es) 2006-09-29

Family

ID=34465290

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06033213A CO5680416A2 (es) 2003-10-16 2006-04-05 Preparacion de derivados de 3-azabiciclo [3,1,0]hexano

Country Status (17)

Country Link
US (1) US7129263B2 (enExample)
EP (1) EP1675829A1 (enExample)
JP (1) JP2007508367A (enExample)
KR (1) KR20060096038A (enExample)
CN (1) CN1867548A (enExample)
AR (1) AR046592A1 (enExample)
AU (1) AU2004281229A1 (enExample)
BR (1) BRPI0415459A (enExample)
CA (1) CA2540860A1 (enExample)
CO (1) CO5680416A2 (enExample)
IL (1) IL174596A0 (enExample)
MX (1) MXPA06004278A (enExample)
NO (1) NO20062152L (enExample)
RU (1) RU2006112576A (enExample)
TW (1) TW200524866A (enExample)
WO (1) WO2005037790A1 (enExample)
ZA (1) ZA200601964B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2314289T3 (es) 2002-12-10 2009-03-16 Wyeth Derivados del acido 1h-indol-3-il glioxilico sustituidos con arilo, ariloxi y alquloxi como inhibidores del inhibidor del activador del plasminogeno-1(pai-1).
MXPA06004279A (es) * 2003-10-14 2006-06-28 Pfizer Prod Inc Derivados biciclicos [3.1.0] como inhibidores del transportador de glicina.
WO2008075162A2 (en) * 2006-12-15 2008-06-26 Pfizer Limited Selective mu opioid receptor antagonists for the treatment of female sexual dysfunction
BR112013007566A2 (pt) 2010-09-28 2016-08-02 Panacea Biotec Ltd novos compostos bicíclicos
EP3610890A1 (en) 2012-11-14 2020-02-19 The Johns Hopkins University Methods and compositions for treating schizophrenia
RU2701861C1 (ru) 2013-11-20 2019-10-02 Санва Кагаку Кенкюсо Ко., Лтд. Новое производное 3-азабицикло[3.1.0]гексана и его применение в медицинских целях
CA2985327A1 (en) * 2015-05-20 2016-11-24 Sanwa Kagaku Kenkyusho Co., Ltd. Crystal of salt of 3-azabicyclo[3.1.0]hexane derivative and pharmaceutical use thereof
WO2019173173A1 (en) * 2018-03-05 2019-09-12 E. I. Du Pont De Nemours And Company Process and intermidiates for the preparation of certain mesoionic pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
EP1440059B1 (en) * 2001-10-22 2008-04-16 Pfizer Products Inc. 3-azabicyclo(3.1.0)hexane derivatives as opioid receptor antagonists

Also Published As

Publication number Publication date
US7129263B2 (en) 2006-10-31
TW200524866A (en) 2005-08-01
JP2007508367A (ja) 2007-04-05
ZA200601964B (en) 2007-04-25
IL174596A0 (en) 2006-08-20
AR046592A1 (es) 2005-12-14
MXPA06004278A (es) 2006-06-28
NO20062152L (no) 2006-05-12
CA2540860A1 (en) 2005-04-28
CN1867548A (zh) 2006-11-22
BRPI0415459A (pt) 2006-12-19
WO2005037790A1 (en) 2005-04-28
KR20060096038A (ko) 2006-09-05
US20050113437A1 (en) 2005-05-26
EP1675829A1 (en) 2006-07-05
RU2006112576A (ru) 2006-08-27
AU2004281229A1 (en) 2005-04-28

Similar Documents

Publication Publication Date Title
BR0114986A (pt) Composto, composição farmacêutica, uso de pelo menos um composto ou um sal, solvato ou hidrato deste farmaceuticamente aceitáveis, e, processo para preparar triazolona partir de uma acil semicarbazida.
AR051839A1 (es) Metodo para preparar n-fenilpirazol -1- carboxamidas
TW200600508A (en) Cyclic amide derivative, and its production and use
AR052558A1 (es) Derivados de tiazol-4-carboxamida como antagonistas de mglur5
CO5611131A2 (es) Derivados de 5-feniltiazol y su uso como inhibidores de pi3 cinasa
ES2322602T3 (es) Compuestos heterotetraciclicos condensados y su uso como inhibidor de polimerasa del vhc.
AR035548A1 (es) Compuestos organicos
AR043049A1 (es) Derivados de hidantoina, proceso de preparacion del mismo y composicion farmaceutica
CO6140053A2 (es) Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas
CO5680416A2 (es) Preparacion de derivados de 3-azabiciclo [3,1,0]hexano
AR015512A1 (es) Derivados ciclicos n-acilo amina, un procedimiento para su preparacion, un intermediario y una composicion farmaceutica
ECSP10010006A (es) Derivado de oxopirazina y herbicida
ECSP055974A (es) Síntesis de cloruros de 4 amino-2-butenoil y su uso en la preparación de 3-ciano quinolinas
AR049401A1 (es) Aza-biciclononanos
PE20070009A1 (es) Tigeciclina y metodos para su preparacion
WO2008136444A1 (ja) 縮合複素環誘導体
CO5601021A2 (es) Derivados de quinazolinona, composiciones farmaceuticas que los contienen y su proceso de preparacion y su uso como antagonistas cb
PE20061447A1 (es) Tigeciclina y metodos para preparar 9-aminominociclina
PE20020906A1 (es) Inhibidores de peptido-deformilasa
CO5570675A2 (es) Compuestos sustituidos de benzimidazolo y su uso para el tratamiento del cancer
PE20031032A1 (es) Derivados de guanidinilo como agonistas del receptor de melanocortina-4
ECSP066992A (es) ÁCIDO 2-{[2-(2-METILAMINOPIRIMIDIN-4-IL)-1H-INDOL-5-CARBONIL]AMINO}-3-(FENILPIRIDIN-2-ILAMINO)PROPIÓNICOSUSTANCIALMENTE PURO COMO INHIBIDOR DE LA CINASA IkB
CO6230983A2 (es) Derivados de 1 - oxo - 1, 2 - dihidro - isoqinolina, procesos para su preparacion y composiciones farmaceuticas que los contienen
AR034206A1 (es) Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos
UY30552A1 (es) Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones

Legal Events

Date Code Title Description
FC Application refused