CO6140053A2 - Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas - Google Patents

Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas

Info

Publication number
CO6140053A2
CO6140053A2 CO09002500A CO09002500A CO6140053A2 CO 6140053 A2 CO6140053 A2 CO 6140053A2 CO 09002500 A CO09002500 A CO 09002500A CO 09002500 A CO09002500 A CO 09002500A CO 6140053 A2 CO6140053 A2 CO 6140053A2
Authority
CO
Colombia
Prior art keywords
compound
formula
contact
reaction medium
halobenzamids
Prior art date
Application number
CO09002500A
Other languages
English (en)
Inventor
Richard F Davis
Rafael Shapiro
Eric De Guyon Taylor
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of CO6140053A2 publication Critical patent/CO6140053A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride

Abstract

1.- Un método para preparar un compuesto de la Fórmula 1en donde R1 es H, alquilo C1-C4, ciclopropilo, ciclopropilmetilo o metilciclopropilo;R2 es CH3 o Cl; yX es Cl o Br;que comprende:poner en contacto un compuesto de la Fórmula 2con un compuesto de la Fórmula 3 R1-NH2 3en la presencia de un ácido carboxílico.2.- El método de la reivindicación 1 en donde dicho contacto está en un medio de reacción sustancialmente anhidro que comprende un disolvente orgánico adecuado.3.- El método de la reivindicación 1 en donde dicho contacto está en un medio de reacción que comprende acetato de etilo.4.- El método de la reivindicación 1 en donde el compuesto de la Fórmula 3 se agrega a la mezcla que comprende el compuesto de la Fórmula 2 y el ácido carboxílico.5.- El método de la reivindicación 1 en donde dicho contacto está en un medio de reacción que tiene un pH en un rango desde aproximadamente 3 a aproximadamente 7.6.- El método de la reivindicación 1 en donde el compuesto de la Fórmula 2 se prepara al poner en contacto un compuesto de la Fórmula 4en donde R3 es alquilo C1-C6 o alquenilo C3-C6, cada uno sustituido opcionalmente con hasta 3 halógenos y hasta 1 fenilo; con tribromuro de fósforo.7.- El método de la reivindicación 1 en donde R1 es CH3, R2 es CH3, y X es Cl.
CO09002500A 2006-07-19 2009-01-14 Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas CO6140053A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83178106P 2006-07-19 2006-07-19

Publications (1)

Publication Number Publication Date
CO6140053A2 true CO6140053A2 (es) 2010-03-19

Family

ID=38819811

Family Applications (1)

Application Number Title Priority Date Filing Date
CO09002500A CO6140053A2 (es) 2006-07-19 2009-01-14 Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas

Country Status (23)

Country Link
US (1) US8153844B2 (es)
EP (2) EP2044002B1 (es)
JP (1) JP2009543861A (es)
KR (1) KR101433395B1 (es)
CN (1) CN101600682B (es)
AR (1) AR061924A1 (es)
AU (1) AU2007275836B2 (es)
BR (1) BRPI0713190B1 (es)
CA (1) CA2656357C (es)
CO (1) CO6140053A2 (es)
DK (2) DK2394983T3 (es)
ES (2) ES2525152T3 (es)
IL (1) IL195546A (es)
MX (1) MX306717B (es)
MY (1) MY147440A (es)
PL (2) PL2394983T3 (es)
RS (1) RS53348B (es)
RU (1) RU2443679C2 (es)
TW (1) TWI403494B (es)
UA (1) UA99257C2 (es)
VN (1) VN28357A1 (es)
WO (1) WO2008010897A2 (es)
ZA (1) ZA200810231B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7859223B2 (en) 2007-01-31 2010-12-28 Analog Devices, Inc. Battery montoring apparatus and daisy chain interface suitable for use in a battery monitoring apparatus
CN101333213B (zh) 2008-07-07 2011-04-13 中国中化股份有限公司 1-取代吡啶基-吡唑酰胺类化合物及其应用
GB2463318A (en) * 2008-09-12 2010-03-17 Syngenta Participations Ag Preparation of anthranilamide derivatives containing a pyridinylpyrazole moiety
CN101747318A (zh) * 2008-12-11 2010-06-23 中国中化集团公司 1-(3，5-二氯吡啶基)-1h-5-吡唑羧酸酯类化合物
PT2379526E (pt) 2008-12-18 2015-09-17 Bayer Ip Gmbh Amidas de ácido antranílico substituídas por tetrazol como pesticidas
CN101492387B (zh) * 2009-03-09 2012-07-25 浙江大学 2-氨基-5-氯-n,3-二甲基苯甲酰胺的制备方法
AR079009A1 (es) * 2009-10-20 2011-12-21 Sumitomo Chemical Co Composicion y metodo para controlar plagas de artropodos
CN102047914B (zh) * 2009-10-29 2014-02-26 中国中化股份有限公司 一种杀虫剂组合物
ES2534877T3 (es) 2010-04-16 2015-04-29 Bayer Intellectual Property Gmbh Antranilamidas sustituidas con triazol como pesticidas
CN102127065B (zh) * 2010-05-19 2014-02-12 江苏省农药研究所股份有限公司 邻杂环甲酰取代苯胺类化合物及其合成方法和应用
CN102285963B (zh) * 2010-06-21 2014-04-09 中国中化股份有限公司 3-甲氧基吡唑酰胺类化合物及其应用
MX363730B (es) * 2012-02-07 2019-04-01 Bayer Ip Gmbh Procedimiento para la preparacion de derivados de acido antranilico sustituidos.
JP6571532B2 (ja) * 2013-02-20 2019-09-04 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ アントラニルアミド化合物、それらの混合物およびそれらの殺有害生物剤としての使用
EP3057945A1 (en) * 2013-10-17 2016-08-24 Basf Se Process for preparing substituted isatoic acid anhydride compounds and derivatives thereof
CN104003976B (zh) * 2014-05-07 2016-03-16 肇庆市真格生物科技有限公司 多取代吡啶基吡唑酰胺及其制备方法和用途
TWI678354B (zh) 2014-05-29 2019-12-01 新加坡商艾佛艾姆希農業新加坡有限公司 藉空氣氧化製備３-甲基-２-硝基苯甲酸之製程
CN104031037B (zh) * 2014-06-23 2017-01-18 南京工业大学 一种含1，3，4‑噁二唑结构的甲酰苯胺类化合物及其制备方法与应用
CN104370899A (zh) * 2014-10-23 2015-02-25 南京工业大学 一种含1,2,4-噁二唑结构的甲酰苯胺类化合物及其制备方法与应用
CN105130953A (zh) * 2015-09-22 2015-12-09 江西安利达化工有限公司 一种苯甲酰胺类化合物及其制备方法
CN106818764A (zh) * 2017-01-16 2017-06-13 山东省联合农药工业有限公司 一种新农药的杀虫组合物
CN107089970B (zh) 2017-05-26 2020-06-16 迈克斯(如东)化工有限公司 一种制备n-酰基邻氨基苯甲酰胺的方法
KR20200112815A (ko) 2017-12-20 2020-10-05 피아이 인더스트리스 엘티디. 살충제로서의 피라졸로피리딘-디아미드 용도 및 그의 제조 방법
WO2019123194A1 (en) 2017-12-20 2019-06-27 Pi Industries Ltd. Anthranilamides, their use as insecticide and processes for preparing the same.
CN108184859A (zh) * 2017-12-29 2018-06-22 广东真格生物科技有限公司 一种含有丁氯虫酰胺和拟除虫菊酯杀虫组合物及其应用
JP7307079B2 (ja) 2018-01-30 2023-07-11 ピーアイ インダストリーズ リミテッド 新規アントラニルアミド、殺虫剤としてのその使用およびその製造方法
CA3129876A1 (en) 2019-02-18 2020-08-27 Pi Industries Ltd. A process for preparing anthranilic diamides and intermediates thereof
CN114621130A (zh) * 2019-11-01 2022-06-14 Fmc公司 用于合成2-氨基-5-氯-n,3-二甲基苯甲酰胺的高效新方法
AR123526A1 (es) 2020-09-17 2022-12-14 Pi Industries Ltd Un proceso para la síntesis de compuestos antranílicos de ácido / amida e intermediarios de los mismos
AR123593A1 (es) 2020-09-26 2022-12-21 Pi Industries Ltd Un proceso para la síntesis de compuestos antranílicos de ácido / amida e intermedios de los mismos
CN113603615B (zh) * 2020-11-03 2023-01-06 利尔化学股份有限公司 一种5-卤代-2[(烷氧基羰基)氨基]-3-甲基苯甲酸的制备方法
WO2022162447A1 (en) * 2021-01-27 2022-08-04 Laurus Labs Limited Processes for preparation of chlorantraniliprole or a salt or its intermediates thereof
WO2023012081A1 (en) 2021-08-05 2023-02-09 Syngenta Crop Protection Ag Method for controlling diamide resistant pests & compounds therefor
CN114621145A (zh) * 2022-03-23 2022-06-14 南开大学 一类氟代苯基和三氟乙氧基吡唑的双酰胺类衍生物及其制备方法和用途
TW202346260A (zh) 2022-04-14 2023-12-01 美商富曼西公司 用於製備5-氯-2-((乙氧基羰基)胺基)-3-甲基苯甲酸之方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US930295A (en) * 1909-02-20 1909-08-03 James L O King Water-elevator.
DE939151C (de) * 1952-11-29 1956-02-16 Bayer Ag Verfahren zur Herstellung von Aminocarbonsaeure-N, N-alkylenimiden
US3515744A (en) 1966-01-07 1970-06-02 Basf Ag Substituted n-phenyl carbamates
GB1488903A (en) * 1974-05-31 1977-10-19 Guerbet Sa X-ray contrast media
DE2719020C2 (de) 1977-04-28 1986-02-20 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Anthranilamiden
DE2750292A1 (de) 1977-11-10 1979-05-17 Basf Ag Verfahren zur herstellung von 3,5-dichloranthranilsaeure
DE2925175A1 (de) 1979-06-22 1981-01-08 Basf Ag Verfahren zur herstellung von isatosaeureanhydriden
GB8524663D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinazoline derivatives
US4873232A (en) 1986-10-29 1989-10-10 Syntex Novel use for carbamoyl benzoates
DE3737497A1 (de) 1987-11-05 1989-05-18 Hoechst Ag Verfahren zur herstellung von 6-chlorisatosaeureanhydrid
US5872550A (en) 1997-06-09 1999-02-16 Raytheon Company Compressible coaxial interconnection with integrated environmental seal
TWI325302B (en) 2001-08-13 2010-06-01 Du Pont Benzoxazinone compounds
AR036872A1 (es) 2001-08-13 2004-10-13 Du Pont Compuesto de antranilamida, composicion que lo comprende y metodo para controlar una plaga de invertebrados
EA012929B1 (ru) 2004-11-18 2010-02-26 Е.И. Дюпон Де Немур Энд Компани Антраниламидные инсектициды
US8946444B2 (en) 2004-11-23 2015-02-03 Ptc Therapeutics, Inc. Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control
TWI363756B (en) 2004-12-07 2012-05-11 Du Pont Method for preparing n-phenylpyrazole-1-carboxamides

Also Published As

Publication number Publication date
IL195546A (en) 2013-04-30
CN101600682A (zh) 2009-12-09
PL2044002T3 (pl) 2014-09-30
DK2394983T3 (en) 2014-12-15
ES2470566T3 (es) 2014-06-24
US20090306372A1 (en) 2009-12-10
EP2044002B1 (en) 2014-04-16
RU2009105669A (ru) 2010-08-27
IL195546A0 (en) 2009-09-01
RS53348B (en) 2014-10-31
TWI403494B (zh) 2013-08-01
WO2008010897A3 (en) 2009-05-07
AR061924A1 (es) 2008-10-01
TW200815321A (en) 2008-04-01
US8153844B2 (en) 2012-04-10
AU2007275836B2 (en) 2012-07-12
WO2008010897A2 (en) 2008-01-24
JP2009543861A (ja) 2009-12-10
CA2656357C (en) 2014-05-06
RU2443679C2 (ru) 2012-02-27
ZA200810231B (en) 2010-07-28
MY147440A (en) 2012-12-14
ES2525152T3 (es) 2014-12-18
EP2044002A2 (en) 2009-04-08
BRPI0713190B1 (pt) 2016-11-16
CA2656357A1 (en) 2008-01-24
DK2044002T3 (da) 2014-07-07
KR101433395B1 (ko) 2014-08-26
MX2009000572A (es) 2009-01-27
MX306717B (es) 2013-01-15
KR20090031614A (ko) 2009-03-26
BRPI0713190A2 (pt) 2012-03-20
CN101600682B (zh) 2013-07-24
PL2394983T3 (pl) 2015-03-31
EP2394983A1 (en) 2011-12-14
EP2394983B1 (en) 2014-09-24
UA99257C2 (ru) 2012-08-10
AU2007275836A1 (en) 2008-01-24
VN28357A1 (en) 2011-12-26

Similar Documents

Publication Publication Date Title
CO6140053A2 (es) Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas
AR079491A1 (es) Metodos de sintesis de inhibidores del factor xa tal como el betrixaban y composiciones farmaceuticas que contienen la base libre de betrixaban o su sal sustancialmente pura.
CO6220910A2 (es) Proceso para la producir compuestos pesticidas de benzamidas
AR060489A1 (es) Derivados del acido benzoazepin - oxi- acetico como agonistas de ppar - delta usados para aumentar hdl- c, reducir ldl-c y reducir colesterol
ATE538085T1 (de) Verfahren zur herstellung von 2-amino-5- cyanobenzoesäurederivaten
AR079495A1 (es) Derivados de fenilimidazol heteroaromaticos como inhibidores de enzima pde10a
RU2012116208A (ru) Способ получения n-ацилбифенилаланина
ATE477234T1 (de) Synthese von phenolischen estern von hydroxymethylphenolen
PE20091182A1 (es) DERIVADOS DE IMIDAZO[1,2-a]PIRIDIN-2-CARBOXAMIDAS, SU PREPARACION Y SU APLICACION EN TERAPEUTICA
CO6251235A2 (es) Compuestos derivados de azetidinas su preparacion y su aplicacion en terapeutica
CO6351789A2 (es) Derivados de carbamatos de alquiltiazoles, su preparacion y su aplicacion en terapeutica
CO6231027A2 (es) Metodos e intermediarios para preparar compuestos de lactama lactoma de 8 atomos de carbono activos como inhibidores de renina
AR073043A1 (es) Compuestos de azetidinas polisustituidos, composiciones farmaceuticas que los contienen, metodo de preparacion y uso de los mismos en el tratamiento de enfermedades respiratorias, metabolicas y del sistema nervioso central, entre otras.
AR049668A1 (es) Proceso quimico para preparar esteres de 4,4 - difluorometil - 3 - oxo - butanoico por reaccion entre una amida y un ester.
ES2278552T1 (es) Preparacion de intermediarios de tadalafil.
BR112013008675A2 (pt) métodos e composições para o tratamento de diabetes e dislipidemia
PE20070075A1 (es) Procedimiento de preparacion para compuestos inhibidores de renina
CO6231030A2 (es) Metodos para preparar compuestos basados en imidazol como potentes inhibidores de respuesta inmune
AR051936A1 (es) Proceso para la preparacion de pirazoles
WO2010003704A3 (en) Process for making 1-hydroxyalkylidene-1,1-biphosphonic acids
PE20090602A1 (es) Nuevos compuestos
CO6280473A2 (es) Compuestos de 1,2,4- triazin-3,5-diona adecuados para el tratamiento de trastornos que responden a la modulacion del receptor de dopamina d3
BR112014018985B1 (pt) método para preparar um composto
AR077332A1 (es) Procesos para la alquilacion de pirazoles
AR066430A1 (es) Proceso para preparar inhibidores de aromatasa y forma cristalina de exemestano