JP2004525888A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004525888A5 JP2004525888A5 JP2002559370A JP2002559370A JP2004525888A5 JP 2004525888 A5 JP2004525888 A5 JP 2004525888A5 JP 2002559370 A JP2002559370 A JP 2002559370A JP 2002559370 A JP2002559370 A JP 2002559370A JP 2004525888 A5 JP2004525888 A5 JP 2004525888A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- methoxy
- phenylsulfonyl
- integer
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *OC([C@](CCC1)N1C([C@@](CC1CCCCC1)NCC(NCC*O)=O)=O)=O Chemical compound *OC([C@](CCC1)N1C([C@@](CC1CCCCC1)NCC(NCC*O)=O)=O)=O 0.000 description 3
- LDDXTZJQVINROX-UHFFFAOYSA-N CNCc(cc1)ccc1C(N)=N Chemical compound CNCc(cc1)ccc1C(N)=N LDDXTZJQVINROX-UHFFFAOYSA-N 0.000 description 2
- MSPORBDQRNSRAM-UHFFFAOYSA-N CNCC(CC1)CCN1C(N)=N Chemical compound CNCC(CC1)CCN1C(N)=N MSPORBDQRNSRAM-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10102878A DE10102878A1 (de) | 2001-01-23 | 2001-01-23 | Oligo- oder Polyalkylengekoppelte Thrombininhibitoren |
| PCT/EP2002/000652 WO2002059065A2 (de) | 2001-01-23 | 2002-01-23 | Oligo- oder polyalkylenglycolgekoppelte thrombininhibitoren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525888A JP2004525888A (ja) | 2004-08-26 |
| JP2004525888A5 true JP2004525888A5 (enExample) | 2008-04-10 |
| JP4461217B2 JP4461217B2 (ja) | 2010-05-12 |
Family
ID=7671444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002559370A Expired - Fee Related JP4461217B2 (ja) | 2001-01-23 | 2002-01-23 | オリゴまたはポリアルキレングリコール結合トロンビン阻害剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7407982B2 (enExample) |
| EP (1) | EP1355674B1 (enExample) |
| JP (1) | JP4461217B2 (enExample) |
| AT (1) | ATE485838T1 (enExample) |
| CA (1) | CA2431487C (enExample) |
| DE (2) | DE10102878A1 (enExample) |
| WO (1) | WO2002059065A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10162521A1 (de) * | 2001-12-19 | 2003-07-17 | Goetz Nowak | Verwendung von molekulargewichtserweiterten Substanzen in der Tumortherapie |
| AU2003219039A1 (en) * | 2002-03-11 | 2003-09-22 | Curacyte Ag | Urokinase inhibitors, production and use thereof |
| DE10301300B4 (de) | 2003-01-15 | 2009-07-16 | Curacyte Chemistry Gmbh | Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein |
| DE10342108A1 (de) * | 2003-09-11 | 2005-04-14 | Curacyte Chemistry Gmbh | Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung |
| ATE480561T1 (de) | 2004-10-19 | 2010-09-15 | Lonza Ag | Verfahren zur festphasen-peptidsynthese |
| DE102005044319A1 (de) * | 2005-09-16 | 2007-03-22 | Curacyte Chemistry Gmbh | 2-(Aminomethyl)-5-Chlor-Benzylamid-Derivate und ihre Verwendung als Hemmstoffe des Gerinnungsfaktors Xa |
| DE102006048300A1 (de) * | 2006-01-26 | 2007-08-02 | Hellstern, Peter, Prof. Dr.med. | Inhibitoren des Blutgerinnungsfaktors Xa zur Verwendung als Antikoagulans |
| EP2072070B1 (en) * | 2006-09-15 | 2016-11-09 | Toray Industries, Inc. | Substrate and method for production thereof |
| WO2008032400A1 (fr) * | 2006-09-15 | 2008-03-20 | Toray Industries, Inc. | Procédé pour la production d'un substrat modifié |
| DE102006050672A1 (de) | 2006-10-24 | 2008-04-30 | Curacyte Discovery Gmbh | Hemmstoffe des Plasmins und des Plasmakallikreins |
| DE102007033787A1 (de) | 2007-07-09 | 2009-01-15 | Aesculap Ag | Gefäßprothese mit reduzierter Thrombogenität |
| JP2012502906A (ja) * | 2008-09-17 | 2012-02-02 | ネクター セラピューティックス | オリゴマー−プロテアーゼ阻害剤コンジュゲート |
| US8835710B2 (en) * | 2009-03-24 | 2014-09-16 | Mead Johnson Nutrition Company | Animal model for infant pathologies |
| TWI476020B (zh) | 2009-12-24 | 2015-03-11 | Toray Industries | 具有抗血液凝固作用之親水性高分子化合物、包含其之醫療器材或醫療材料之表面處理劑、以及經其處理之醫療器材或醫療材料 |
| EP2558087A4 (en) | 2010-03-11 | 2013-09-11 | Univ New York | AMID COMPOUNDS AS RORYT MODULATORS AND ITS USES |
| EP2655399B1 (en) * | 2010-12-21 | 2017-09-27 | The Medicines Company (Leipzig) GmbH | Trypsin-like serine protease inhibitors, their preparation and use as selective inhibitors of the clotting factors iia and xa |
| TW201309354A (zh) | 2011-06-23 | 2013-03-01 | Toray Industries | 醫療材料 |
| TW201311774A (zh) | 2011-06-23 | 2013-03-16 | Toray Industries | 具有抗血液凝固作用的疏水性高分子化合物 |
| RU2014102166A (ru) * | 2011-06-24 | 2015-07-27 | Кандзи ИНОУЕ | Устройство для захвата свободных тромбов |
| RU2015148536A (ru) * | 2013-04-12 | 2017-05-18 | Торэй Индастриз, Инк. | Антитромботический искусственный кровеносный сосуд |
| RU2016125452A (ru) * | 2013-11-28 | 2018-01-10 | Торэй Индастриз, Инк. | Антитромботический материал |
| CN105979910B (zh) * | 2014-02-12 | 2018-05-18 | 东丽株式会社 | 人工血管 |
| AU2017340701A1 (en) | 2016-10-07 | 2019-04-04 | Toray Industries, Inc. | Tubular woven fabric |
| EP3603573B1 (en) | 2017-03-31 | 2023-03-22 | Toray Industries, Inc. | Cylindrical structure |
| CN117497842B (zh) * | 2023-12-27 | 2024-03-12 | 江苏蓝固新能源科技有限公司 | 一种聚合物电解质和制备方法及其在二次电池中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5663141A (en) | 1989-12-01 | 1997-09-02 | Basf Aktiengesellschaft | Hirudin/polyalkylene glycol conjugates and hirudin muteins |
| US5583146A (en) * | 1992-12-02 | 1996-12-10 | Bristol-Myers Squibb Company | Heterocyclic thrombin inhibitors |
| DE4342154A1 (de) * | 1993-12-10 | 1995-06-14 | Behringwerke Ag | Amidinophenylalaninderivate, Verfahren zu deren Herstellung, deren Verwendung und diese enthaltende Mittel als Antikoagulantien |
| US5914319A (en) * | 1995-02-27 | 1999-06-22 | Eli Lilly And Company | Antithrombotic agents |
| US5798377A (en) * | 1996-10-21 | 1998-08-25 | Merck & Co., Inc. | Thrombin inhibitors |
| AU5773798A (en) | 1997-01-29 | 1998-08-18 | Polymasc Pharmaceuticals Plc | Pegylation process |
-
2001
- 2001-01-23 DE DE10102878A patent/DE10102878A1/de not_active Ceased
-
2002
- 2002-01-23 US US10/344,722 patent/US7407982B2/en not_active Expired - Fee Related
- 2002-01-23 EP EP02708308A patent/EP1355674B1/de not_active Expired - Lifetime
- 2002-01-23 CA CA2431487A patent/CA2431487C/en not_active Expired - Fee Related
- 2002-01-23 JP JP2002559370A patent/JP4461217B2/ja not_active Expired - Fee Related
- 2002-01-23 DE DE50214734T patent/DE50214734D1/de not_active Expired - Lifetime
- 2002-01-23 WO PCT/EP2002/000652 patent/WO2002059065A2/de not_active Ceased
- 2002-01-23 AT AT02708308T patent/ATE485838T1/de active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005532287A5 (enExample) | ||
| JP2002518384A5 (enExample) | ||
| JP2007534702A5 (enExample) | ||
| JP2001525411A5 (enExample) | ||
| JP2001526218A5 (enExample) | ||
| WO2001087845A3 (en) | N-containing heterocyclic compounds and their use as 5-ht antagonists | |
| JP2005529956A5 (enExample) | ||
| JP2003503387A5 (enExample) | ||
| JP2005528325A5 (enExample) | ||
| JP2008510828A5 (enExample) | ||
| JPH11162650A5 (enExample) | ||
| JP2008535803A5 (enExample) | ||
| CY1108792T1 (el) | Παραγωγα διοξανιου-2-αλκυλκαρβαμικου, η παρασκευη τους και η εφαρμογη τους στην θεραπευτικη αγωγη | |
| JP2005511545A5 (enExample) | ||
| JP2005529164A5 (enExample) | ||
| JP2006517201A5 (enExample) | ||
| JP2004190075A5 (enExample) | ||
| JP2003221386A5 (enExample) | ||
| NO20055655L (no) | Anvendelse av azetidinkarboksamidderivater i terapi | |
| JP2007501210A5 (enExample) | ||
| JP2006518765A5 (enExample) | ||
| JP2005526149A5 (enExample) | ||
| JP2009522364A5 (enExample) | ||
| JP2006522034A5 (enExample) | ||
| JP2007512259A5 (enExample) |