RU2005106871A - Ингибиторы протеинкиназ и их применение - Google Patents

Ингибиторы протеинкиназ и их применение Download PDF

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Publication number
RU2005106871A
RU2005106871A RU2005106871/04A RU2005106871A RU2005106871A RU 2005106871 A RU2005106871 A RU 2005106871A RU 2005106871/04 A RU2005106871/04 A RU 2005106871/04A RU 2005106871 A RU2005106871 A RU 2005106871A RU 2005106871 A RU2005106871 A RU 2005106871A
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Russia
Prior art keywords
disease
methyl
independently selected
nrc
phenyl
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RU2005106871/04A
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English (en)
Russian (ru)
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Джон КОШРАН (US)
Джон КОШРАН
Джереми ГРИН (US)
Джереми ГРИН
Майкл Р. ХЭЙЛ (US)
Майкл Р. ХЭЙЛ
Брайан ЛЕДФОРД (US)
Брайан Ледфорд
Франсуа МАЛЬТЕ (US)
Франсуа Мальте
Сугантини НАНТАКУМАР (US)
Сугантини НАНТАКУМАР
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Вертекс Фармасьютикалз Инкорпорейтед (Us)
Вертекс Фармасьютикалз Инкорпорейтед
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Publication of RU2005106871A publication Critical patent/RU2005106871A/ru

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    • C—CHEMISTRY; METALLURGY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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  • Pharmacology & Pharmacy (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
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  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
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  • Ophthalmology & Optometry (AREA)
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RU2005106871/04A 2002-08-14 2003-08-12 Ингибиторы протеинкиназ и их применение RU2005106871A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40325602P 2002-08-14 2002-08-14
US60/403,256 2002-08-14
US41680202P 2002-10-08 2002-10-08
US60/416,802 2002-10-08

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RU2005106871A true RU2005106871A (ru) 2005-10-10

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US (1) US7304071B2 (enExample)
EP (1) EP1546117A2 (enExample)
JP (1) JP4741948B2 (enExample)
KR (1) KR20050042478A (enExample)
AR (1) AR040870A1 (enExample)
AU (1) AU2003262642B2 (enExample)
BR (1) BR0313397A (enExample)
CA (1) CA2495386C (enExample)
MX (1) MXPA05001804A (enExample)
NO (1) NO20051207L (enExample)
NZ (1) NZ538715A (enExample)
PL (1) PL375447A1 (enExample)
RU (1) RU2005106871A (enExample)
TW (1) TW200406388A (enExample)
WO (1) WO2004016597A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2489155C2 (ru) * 2006-03-29 2013-08-10 Велакор Терапеутикс Пти Лтд Лечение нейродегенеративных заболеваний
RU2607033C2 (ru) * 2010-09-28 2017-01-10 Ноно Инк. Пептиды nd2 и способы лечения неврологического заболевания
RU2710743C2 (ru) * 2015-02-04 2020-01-10 Бийондбайо Инк. Гетероциклическое соединение и содержащая его фармацевтическая композиция
US11731956B2 (en) 2018-10-22 2023-08-22 Alumis Inc. Substituted 1,2,4-triazoles as intermediates in the synthesis of TYK2 inhibitors
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