RU2003129265A - Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии - Google Patents

Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии Download PDF

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Publication number
RU2003129265A
RU2003129265A RU2003129265/13A RU2003129265A RU2003129265A RU 2003129265 A RU2003129265 A RU 2003129265A RU 2003129265/13 A RU2003129265/13 A RU 2003129265/13A RU 2003129265 A RU2003129265 A RU 2003129265A RU 2003129265 A RU2003129265 A RU 2003129265A
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Russia
Prior art keywords
bacterial strain
group
milk
composition according
pharmaceutical composition
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RU2003129265/13A
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English (en)
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RU2312892C2 (ru
Inventor
Беда Мартин ШТАДЛЕР (CH)
Беда Мартин ШТАДЛЕР
Моник ФОГЕЛ (CH)
Моник ФОГЕЛ
Жак-Эдуар ЖЕРМОН (CH)
Жак-Эдуар ЖЕРМОН
Родолф ФРИЧЕ (CH)
Родолф ФРИЧЕ
Original Assignee
Сосьете де Продюи Нестле С.А. (CH)
Сосьете Де Продюи Нестле С.А.
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Publication of RU2003129265A publication Critical patent/RU2003129265A/ru
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal

Claims (10)

1. Бактериальный штамм группы молочно-кислой бактерии, экспрессирующий поверхностный полипептид, который содержит пептидную последовательность, имитирующую, по меньшей мере, часть конформационного эпитопа молекулы IgE, где указанным поверхностным полипептидом является заякоренная на клеточной поверхности протеаза L. bulgaricus.
2. Бактериальный штамм по п.1, выбранный из группы Lactobacillus или группы Bifidobacterium, или группы Lactococcus, и более предпочтительно происходящий из групп L. acidofilicus, L. johnsomi, L. gasseri, L. casei, L. paracasei или L. reuteri.
3. Бактериальный штамм по любому из предыдущих пунктов, где пептидная последовательность произведена из последовательности, выбранной из SEQ ID No.1 - SEQID No.19.
4. Пищевая композиция, содержащая бактериальный штамм по любому из предыдущих пунктов или его супернатант.
5. Пищевая композиция по п.4, выбранная из группы, состоящей из молока, йогурта, творога, сыра, кисло-молочных продуктов, продуктов на основе ферментированного молока, мороженого, продуктов на основе ферментированных злаков, порошков на основе молока, детских смесей или корма для домашних животных.
6. Пищевая композиция по любому из п.4 или 5, где бактериальный штамм содержится в ней в количестве от 107 до 1012 кое на дозированную форму.
7. Фармацевтическая композиция, содержащая бактериальный штамм по любому из пп.1-3.
8. Фармацевтическая композиция по п.7, где бактериальный штамм содержится в ней в количестве от 1010 до 1012 кое на дозированную форму.
9. Применение бактериального штамма по любому из пп.1-3 для приготовления принимаемого внутрь носителя для лечения аллергии и/или предотвращения появления аллергических реакций.
10. Применение фармацевтической композиции по любому из пп.5-8 для приготовления принимаемого внутрь носителя для лечения аллергии и/или появления начала аллергических реакций.
RU2003129265/13A 2001-03-02 2002-03-04 Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии RU2312892C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01105138.0 2001-03-02
EP01105138A EP1239032A1 (en) 2001-03-02 2001-03-02 Lactic acid bacteria as agents for treating and preventing allergy

Publications (2)

Publication Number Publication Date
RU2003129265A true RU2003129265A (ru) 2005-04-10
RU2312892C2 RU2312892C2 (ru) 2007-12-20

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RU2003129265/13A RU2312892C2 (ru) 2001-03-02 2002-03-04 Молочно-кислые бактерии в качестве агентов для лечения и предотвращения аллергии

Country Status (17)

Country Link
US (1) US7235395B2 (ru)
EP (2) EP1239032A1 (ru)
JP (1) JP2004528034A (ru)
KR (2) KR20030082950A (ru)
CN (1) CN1505678A (ru)
AR (1) AR035761A1 (ru)
AU (1) AU2002256639B2 (ru)
BR (1) BR0207749A (ru)
CA (1) CA2438833A1 (ru)
IL (1) IL157468A0 (ru)
MX (1) MXPA03007881A (ru)
NO (1) NO20033796L (ru)
NZ (1) NZ527861A (ru)
PL (1) PL367208A1 (ru)
RU (1) RU2312892C2 (ru)
WO (1) WO2002086102A1 (ru)
ZA (1) ZA200307680B (ru)

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Publication number Publication date
NO20033796L (no) 2003-10-31
CA2438833A1 (en) 2002-10-31
MXPA03007881A (es) 2003-12-04
EP1239032A1 (en) 2002-09-11
NZ527861A (en) 2005-02-25
WO2002086102A1 (en) 2002-10-31
PL367208A1 (en) 2005-02-21
BR0207749A (pt) 2004-06-01
EP1370640A1 (en) 2003-12-17
CN1505678A (zh) 2004-06-16
AR035761A1 (es) 2004-07-07
KR20080111172A (ko) 2008-12-22
NO20033796D0 (no) 2003-08-26
ZA200307680B (en) 2005-01-13
IL157468A0 (en) 2004-03-28
US20040265290A1 (en) 2004-12-30
US7235395B2 (en) 2007-06-26
AU2002256639B2 (en) 2006-10-19
KR20030082950A (ko) 2003-10-23
JP2004528034A (ja) 2004-09-16
RU2312892C2 (ru) 2007-12-20

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Effective date: 20110305