RS64690B1 - Konjugati biparatopskog anti-her2 antitela i leka i postupci za njihovu upotrebu - Google Patents
Konjugati biparatopskog anti-her2 antitela i leka i postupci za njihovu upotrebuInfo
- Publication number
- RS64690B1 RS64690B1 RS20230943A RSP20230943A RS64690B1 RS 64690 B1 RS64690 B1 RS 64690B1 RS 20230943 A RS20230943 A RS 20230943A RS P20230943 A RSP20230943 A RS P20230943A RS 64690 B1 RS64690 B1 RS 64690B1
- Authority
- RS
- Serbia
- Prior art keywords
- antibody
- her2
- antigen
- binding
- linker
- Prior art date
Links
Classifications
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- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
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- Veterinary Medicine (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862642483P | 2018-03-13 | 2018-03-13 | |
| US201862658477P | 2018-04-16 | 2018-04-16 | |
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| EP3223848B1 (en) * | 2014-11-27 | 2024-11-27 | Zymeworks BC Inc. | Methods of using bispecific antigen-binding constructs targeting her2 |
| US11028182B2 (en) | 2015-05-13 | 2021-06-08 | Zymeworks Inc. | Antigen-binding constructs targeting HER2 |
| ES2958933T3 (es) | 2018-03-13 | 2024-02-16 | Zymeworks Bc Inc | Conjugados de anticuerpo biparatópico anti-HER2-fármaco y métodos de uso |
| US20220387633A1 (en) * | 2019-08-14 | 2022-12-08 | The Regents Of The University Of California | Smart peptides and transformable nanoparticles for cancer immunotherapy |
| US20230192877A1 (en) * | 2020-03-30 | 2023-06-22 | National Institutes Of Biomedical Inovation, Health And Nutriton | Epitope region-bridging biparatopic antibody and method for producing same |
| TW202309085A (zh) * | 2021-04-26 | 2023-03-01 | 大陸商軒竹生物科技股份有限公司 | 雙特異性抗體結合物 |
| WO2023141714A1 (en) * | 2022-01-26 | 2023-08-03 | Zymeworks Bc Inc. | Methods of using anti-her2 biparatopic antibody-drug conjugates in the treatment of cancer |
| CN116003609B (zh) * | 2022-07-04 | 2026-03-06 | 倍而达药业(苏州)有限公司 | erb-B2双特异性抗体、药物组合物及其用途 |
| WO2024230301A1 (zh) * | 2023-05-09 | 2024-11-14 | 诺灵生物医药科技(北京)有限公司 | 一种抗体偶联药物及其用途 |
| WO2025162287A1 (zh) * | 2024-01-29 | 2025-08-07 | 正大天晴药业集团股份有限公司 | 抗her2抗体药物偶联物治疗肠癌的用途 |
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