RS61742B1 - Imunomodulatori za pet-snimanje - Google Patents
Imunomodulatori za pet-snimanjeInfo
- Publication number
- RS61742B1 RS61742B1 RS20210499A RSP20210499A RS61742B1 RS 61742 B1 RS61742 B1 RS 61742B1 RS 20210499 A RS20210499 A RS 20210499A RS P20210499 A RSP20210499 A RS P20210499A RS 61742 B1 RS61742 B1 RS 61742B1
- Authority
- RS
- Serbia
- Prior art keywords
- compound
- subject
- ethoxy
- tissues
- disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/037—Emission tomography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/12—Arrangements for detecting or locating foreign bodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- High Energy & Nuclear Physics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662338872P | 2016-05-19 | 2016-05-19 | |
| PCT/US2017/033004 WO2017201111A1 (en) | 2016-05-19 | 2017-05-17 | Pet-imaging immunomodulators |
| EP17728696.0A EP3458111B1 (en) | 2016-05-19 | 2017-05-17 | Pet-imaging immunomodulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS61742B1 true RS61742B1 (sr) | 2021-05-31 |
Family
ID=59021563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20210499A RS61742B1 (sr) | 2016-05-19 | 2017-05-17 | Imunomodulatori za pet-snimanje |
Country Status (25)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9856292B2 (en) | 2014-11-14 | 2018-01-02 | Bristol-Myers Squibb Company | Immunomodulators |
| US10143746B2 (en) | 2016-03-04 | 2018-12-04 | Bristol-Myers Squibb Company | Immunomodulators |
| US10358463B2 (en) | 2016-04-05 | 2019-07-23 | Bristol-Myers Squibb Company | Immunomodulators |
| WO2018048882A1 (en) | 2016-09-06 | 2018-03-15 | The Research Foundation For The State University Of New York | Positron imaging tomography imaging agent composition and method for bacterial infection |
| US10736976B2 (en) | 2016-12-01 | 2020-08-11 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-PD-L1 antibodies for immuno-PET imaging |
| EP3558395A4 (en) | 2016-12-23 | 2020-08-12 | The Johns Hopkins University | IMAGING OF TUMOR CELLS AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION |
| BR112019016336A2 (pt) | 2017-02-10 | 2020-03-31 | Regeneron Pharmaceuticals, Inc. | Conjugado de anticorpo radiorrotulado, método para imageamento de um tecido que expressa lag3 e para tratar um tumor, e, composto. |
| KR102735038B1 (ko) | 2017-06-23 | 2024-11-28 | 브리스톨-마이어스 스큅 컴퍼니 | Pd-1의 길항제로서 작용하는 면역조정제 |
| MY197688A (en) | 2017-07-24 | 2023-07-05 | Regeneron Pharma | Anti-cd8 antibodies and uses thereof |
| EP3692053A1 (en) | 2017-10-03 | 2020-08-12 | Bristol-Myers Squibb Company | Immunomodulators |
| CN110504017B (zh) * | 2019-07-30 | 2022-06-10 | 哈尔滨医科大学 | 一种示踪剂的制备和使用方法 |
| CN114929728A (zh) | 2020-01-06 | 2022-08-19 | 百时美施贵宝公司 | 免疫调节剂 |
| EP4121442A1 (en) * | 2020-03-16 | 2023-01-25 | Bristol-Myers Squibb Company | Immunomodulators |
| WO2021202501A1 (en) | 2020-03-30 | 2021-10-07 | Bristol-Myers Squibb Company | Immunomodulators |
| US12159403B2 (en) * | 2021-06-18 | 2024-12-03 | The United States Government As Represented By The Department Of Veteran Affairs | Combination of features from biopsies and scans to predict prognosis in SCLC |
| EP4634205A2 (en) * | 2022-12-12 | 2025-10-22 | Merck Sharp & Dohme LLC | Cyclic peptides as pet imaging agents of granzyme b |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US5374548A (en) | 1986-05-02 | 1994-12-20 | Genentech, Inc. | Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor |
| MX9203291A (es) | 1985-06-26 | 1992-08-01 | Liposome Co Inc | Metodo para acoplamiento de liposomas. |
| US5101827A (en) | 1985-07-05 | 1992-04-07 | Immunomedics, Inc. | Lymphographic and organ imaging method and kit |
| US5776093A (en) | 1985-07-05 | 1998-07-07 | Immunomedics, Inc. | Method for imaging and treating organs and tissues |
| US4735210A (en) | 1985-07-05 | 1988-04-05 | Immunomedics, Inc. | Lymphographic and organ imaging method and kit |
| US5328679A (en) | 1988-04-01 | 1994-07-12 | Immunomedics, Inc. | Methods for technetium/rhenium labeling of proteins |
| US5128119A (en) | 1989-06-12 | 1992-07-07 | Immunomedics, Inc. | Methods for technetium/rhenium labeling of f(ab1)2 fragments |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| IL113610A0 (en) | 1994-06-03 | 1995-08-31 | Immunomedics Inc | A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same |
| US5746996A (en) | 1994-06-03 | 1998-05-05 | Immunomedics, Inc. | Thiolation of peptides for radionuclide-based radiodetection and radiotherapy |
| US5869451A (en) | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US5753206A (en) | 1995-06-07 | 1998-05-19 | Immunomedics, Inc. | Radiometal-binding analogues of luteinizing hormone releasing hormone |
| ATE365562T1 (de) | 1996-05-03 | 2007-07-15 | Immunomedics Inc | Zielgerichtete kombinations-immuntherapie für krebs |
| ATE380038T1 (de) | 1996-07-12 | 2007-12-15 | Immunomedics Inc | Radiometall-bindende peptide analoge |
| US6277818B1 (en) | 1998-10-29 | 2001-08-21 | Angstrom Pharmaceuticals, Inc. | Cyclic peptide ligands that target urokinase plasminogen activator receptor |
| CA2302360C (en) | 1997-09-03 | 2005-11-15 | Immunomedics, Inc. | Fluorination of proteins and peptides for f-18 positron emission tomography |
| US9090668B2 (en) | 2007-03-26 | 2015-07-28 | The University Of Tokyo | Process for synthesizing cyclic peptide compound |
| EP2328919A2 (en) | 2008-08-25 | 2011-06-08 | Amplimmune, Inc. | Pd-i antagonists and methods for treating infectious disease |
| US8907053B2 (en) | 2010-06-25 | 2014-12-09 | Aurigene Discovery Technologies Limited | Immunosuppression modulating compounds |
| JP5818237B2 (ja) | 2010-09-09 | 2015-11-18 | 国立大学法人 東京大学 | Ｎ−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法 |
| US10195578B2 (en) | 2010-12-03 | 2019-02-05 | The University Of Tokyo | Peptide library production method, peptide library, and screening method |
| WO2012168944A1 (en) | 2011-06-08 | 2012-12-13 | Aurigene Discovery Technologies Limited | Therapeutic compounds for immunomodulation |
| WO2013010573A1 (en) * | 2011-07-18 | 2013-01-24 | Universitaet Muenster | Compounds with matrix-metalloproteinase inhibitory activity |
| MX2014011353A (es) | 2012-03-29 | 2014-12-05 | Aurigene Discovery Tech Ltd | Inmunomodulacion de compuestos ciclicos del bucle bc de muerte celular programada (pd1) humana. |
| MX355396B (es) | 2012-06-06 | 2018-04-18 | Polyphor Ag | Peptido - mimeticos de la horquilla beta. |
| JP2013253842A (ja) | 2012-06-06 | 2013-12-19 | Univ Of Tokyo | ｐＨ依存的に標的分子に結合するペプチドのスクリーニング方法 |
| MY176706A (en) | 2013-03-15 | 2020-08-19 | Genentech Inc | Biomarkers and methods of treating pd-1 and pd-l1 related conditions |
| US9308236B2 (en) * | 2013-03-15 | 2016-04-12 | Bristol-Myers Squibb Company | Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions |
| HUE039012T2 (hu) | 2013-09-06 | 2018-12-28 | Aurigene Discovery Tech Ltd | Gyûrûs peptidomimetikus vegyületek, mint immunomodulátorok |
| WO2015044900A1 (en) | 2013-09-27 | 2015-04-02 | Aurigene Discovery Technologies Limited | Therapeutic immunomodulating compounds |
| WO2016039749A1 (en) | 2014-09-11 | 2016-03-17 | Bristol-Myers Squibb Company | Macrocyclic inhibitors of the pd-1/pd-l1 and cd80 (b7-1)/pd-li protein/protein interactions |
| US9732119B2 (en) | 2014-10-10 | 2017-08-15 | Bristol-Myers Squibb Company | Immunomodulators |
| US9856292B2 (en) * | 2014-11-14 | 2018-01-02 | Bristol-Myers Squibb Company | Immunomodulators |
| EA037590B1 (ru) * | 2014-11-25 | 2021-04-19 | Бристол-Майерс Сквибб Компани | Связывающиеся с pd-l1 полипептиды на основе 10fn3 домена для визуализации |
| CA2968961A1 (en) | 2014-11-25 | 2016-06-02 | Bristol-Myers Squibb Company | Methods and compositions for 18f-radiolabeling of biologics |
| US9861680B2 (en) | 2014-12-18 | 2018-01-09 | Bristol-Myers Squibb Company | Immunomodulators |
| US9944678B2 (en) | 2014-12-19 | 2018-04-17 | Bristol-Myers Squibb Company | Immunomodulators |
| US20160222060A1 (en) | 2015-02-04 | 2016-08-04 | Bristol-Myers Squibb Company | Immunomodulators |
| US9809625B2 (en) | 2015-03-18 | 2017-11-07 | Bristol-Myers Squibb Company | Immunomodulators |
| US10143746B2 (en) | 2016-03-04 | 2018-12-04 | Bristol-Myers Squibb Company | Immunomodulators |
| US10358463B2 (en) | 2016-04-05 | 2019-07-23 | Bristol-Myers Squibb Company | Immunomodulators |
| US10994033B2 (en) | 2016-06-01 | 2021-05-04 | Bristol-Myers Squibb Company | Imaging methods using 18F-radiolabeled biologics |
| KR102526034B1 (ko) | 2016-11-07 | 2023-04-25 | 브리스톨-마이어스 스큅 컴퍼니 | 면역조정제 |
| KR102735038B1 (ko) | 2017-06-23 | 2024-11-28 | 브리스톨-마이어스 스큅 컴퍼니 | Pd-1의 길항제로서 작용하는 면역조정제 |
| EP3692053A1 (en) | 2017-10-03 | 2020-08-12 | Bristol-Myers Squibb Company | Immunomodulators |
-
2017
- 2017-05-17 HR HRP20210644TT patent/HRP20210644T8/hr unknown
- 2017-05-17 DK DK17728696.0T patent/DK3458111T3/da active
- 2017-05-17 US US16/098,765 patent/US11103605B2/en active Active
- 2017-05-17 EP EP21152813.8A patent/EP3827849A1/en not_active Withdrawn
- 2017-05-17 EP EP17728696.0A patent/EP3458111B1/en active Active
- 2017-05-17 CA CA3024844A patent/CA3024844A1/en active Pending
- 2017-05-17 KR KR1020187036396A patent/KR102378288B1/ko active Active
- 2017-05-17 PL PL17728696T patent/PL3458111T3/pl unknown
- 2017-05-17 SM SM20210238T patent/SMT202100238T1/it unknown
- 2017-05-17 MA MA053402A patent/MA53402A/fr unknown
- 2017-05-17 PT PT177286960T patent/PT3458111T/pt unknown
- 2017-05-17 JP JP2018560588A patent/JP6953444B2/ja active Active
- 2017-05-17 BR BR112018073642-2A patent/BR112018073642A2/pt unknown
- 2017-05-17 HU HUE17728696A patent/HUE054306T2/hu unknown
- 2017-05-17 ES ES17728696T patent/ES2864091T3/es active Active
- 2017-05-17 RS RS20210499A patent/RS61742B1/sr unknown
- 2017-05-17 SI SI201730690T patent/SI3458111T1/sl unknown
- 2017-05-17 LT LTEP17728696.0T patent/LT3458111T/lt unknown
- 2017-05-17 SG SG11201810177VA patent/SG11201810177VA/en unknown
- 2017-05-17 EA EA201892635A patent/EA038019B1/ru unknown
- 2017-05-17 WO PCT/US2017/033004 patent/WO2017201111A1/en not_active Ceased
- 2017-05-17 MX MX2018014028A patent/MX2018014028A/es unknown
- 2017-05-17 AU AU2017268291A patent/AU2017268291B2/en active Active
- 2017-05-17 CN CN201780042462.1A patent/CN109414514B/zh active Active
-
2018
- 2018-11-12 IL IL262962A patent/IL262962B/en active IP Right Grant
-
2021
- 2021-04-29 CY CY20211100375T patent/CY1124241T1/el unknown
- 2021-08-26 US US17/412,612 patent/US20210386876A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20210386876A1 (en) | Pet-imaging immunomodulators | |
| US20220202966A1 (en) | Positron emitting radionuclide labeled peptides for human upar pet imaging | |
| EP3223866B1 (en) | Methods and compositions for 18f-radiolabeling of the fibronectin type (iii) domain | |
| EP4537851A1 (en) | Trifunctional compound and use thereof | |
| JP2021130675A (ja) | 放射性核種錯体を調製するための方法およびキット | |
| US20160303258A1 (en) | Compounds and compositions for imaging gcc-expressing cells | |
| CN115286693B (zh) | 针对癌胚抗原相关细胞黏附分子ceacam6的肿瘤靶向肽及其应用 | |
| Lindeman et al. | FAP Radioligand Linker Optimization improves Tumor Dose and Tumor-to-healthy organ ratios in 4T1 syngeneic model | |
| Liu et al. | Development of an albumin-based PSMA probe with prolonged half-life | |
| Oum et al. | A benzenesulfonamide derivative as a novel PET radioligand for CXCR4 | |
| Lamba et al. | Synthetic 18 F labeled biomolecules that are selective and promising for PET imaging: major advances and applications | |
| Prasanphanich et al. | The effects of linking substituents on the in vivo behavior of site-directed, peptide-based, diagnostic radiopharmaceuticals | |
| CN119775367A (zh) | 一种靶向Nectin-4的双环肽核素配体、探针及其制备方法与应用 | |
| CN117813326A (zh) | 基于放射的导蛋白-1的检测、伴随测试和治疗方法 | |
| Zeglis et al. | Radiopharmaceuticals for imaging in oncology with special emphasis on positron-emitting agents | |
| Lin et al. | Biological Evaluation of [18F] AlF-NOTA-NSC-GLU as a Positron Emission Tomography Tracer for Hepatocellular Carcinoma | |
| CN103275188B (zh) | 放射性标记t140类多肽化合物及其制备方法和应用 | |
| Sun et al. | Synthesis and biological evaluation of 68Ga-DOTA-AngII as a radiotracer for PET/MR imaging of hepatocellular carcinoma | |
| Verena | Development of Bispecific Prostate-specific Membrane Antigen/fibroblast Activation Protein (PSMA/FAP)-Targeting Radiotracers for Prostate Cancer Imaging | |
| Pang et al. | 68Ga-DOTA-Neratinib: A novel small-molecule PET tracer for breast cancer imaging | |
| Hu et al. | Non-invasive HER2 detection in ovarian and breast cancer xenografts with 99m Tc-(HE) 3 Z HER2: V2 | |
| WO2025061971A1 (en) | Functionalized peptides for in-vivo addressing of pd-l1 expression | |
| CN114081969A (zh) | 标记的小分子抗体、及其标记方法和应用 | |
| CN110551075A (zh) | 放射性标记亚谷氨基酸类化合物及其在制备pet显像剂的应用 | |
| Montemagno et al. | Preclinical evaluation of novel mesothelin-specific ligands for SPECT imaging of Triple Negative Breast Cancer. Author names and affiliations. |