AU2017268291B2 - PET-imaging immunomodulators - Google Patents

PET-imaging immunomodulators Download PDF

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Publication number
AU2017268291B2
AU2017268291B2 AU2017268291A AU2017268291A AU2017268291B2 AU 2017268291 B2 AU2017268291 B2 AU 2017268291B2 AU 2017268291 A AU2017268291 A AU 2017268291A AU 2017268291 A AU2017268291 A AU 2017268291A AU 2017268291 B2 AU2017268291 B2 AU 2017268291B2
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Australia
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compound
ethoxy
subject
disease
imaging
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AU2017268291A1 (en
Inventor
Kenneth M. Boy
David J. Donnelly
Joonyoung Kim
Adrienne PENA
Yunhui Zhang
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/12—Arrangements for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2017268291A 2016-05-19 2017-05-17 PET-imaging immunomodulators Active AU2017268291B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662338872P 2016-05-19 2016-05-19
US62/338,872 2016-05-19
PCT/US2017/033004 WO2017201111A1 (en) 2016-05-19 2017-05-17 Pet-imaging immunomodulators

Publications (2)

Publication Number Publication Date
AU2017268291A1 AU2017268291A1 (en) 2019-01-17
AU2017268291B2 true AU2017268291B2 (en) 2022-09-29

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AU2017268291A Active AU2017268291B2 (en) 2016-05-19 2017-05-17 PET-imaging immunomodulators

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US (2) US11103605B2 (cg-RX-API-DMAC7.html)
EP (2) EP3827849A1 (cg-RX-API-DMAC7.html)
JP (1) JP6953444B2 (cg-RX-API-DMAC7.html)
KR (1) KR102378288B1 (cg-RX-API-DMAC7.html)
CN (1) CN109414514B (cg-RX-API-DMAC7.html)
AU (1) AU2017268291B2 (cg-RX-API-DMAC7.html)
BR (1) BR112018073642A2 (cg-RX-API-DMAC7.html)
CA (1) CA3024844A1 (cg-RX-API-DMAC7.html)
CY (1) CY1124241T1 (cg-RX-API-DMAC7.html)
DK (1) DK3458111T3 (cg-RX-API-DMAC7.html)
EA (1) EA038019B1 (cg-RX-API-DMAC7.html)
ES (1) ES2864091T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20210644T8 (cg-RX-API-DMAC7.html)
HU (1) HUE054306T2 (cg-RX-API-DMAC7.html)
IL (1) IL262962B (cg-RX-API-DMAC7.html)
LT (1) LT3458111T (cg-RX-API-DMAC7.html)
MA (1) MA53402A (cg-RX-API-DMAC7.html)
MX (1) MX2018014028A (cg-RX-API-DMAC7.html)
PL (1) PL3458111T3 (cg-RX-API-DMAC7.html)
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RS (1) RS61742B1 (cg-RX-API-DMAC7.html)
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SM (1) SMT202100238T1 (cg-RX-API-DMAC7.html)
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EP3558395A4 (en) 2016-12-23 2020-08-12 The Johns Hopkins University IMAGING OF TUMOR CELLS AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION
BR112019016336A2 (pt) 2017-02-10 2020-03-31 Regeneron Pharmaceuticals, Inc. Conjugado de anticorpo radiorrotulado, método para imageamento de um tecido que expressa lag3 e para tratar um tumor, e, composto.
KR102735038B1 (ko) 2017-06-23 2024-11-28 브리스톨-마이어스 스큅 컴퍼니 Pd-1의 길항제로서 작용하는 면역조정제
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CN110504017B (zh) * 2019-07-30 2022-06-10 哈尔滨医科大学 一种示踪剂的制备和使用方法
CN114929728A (zh) 2020-01-06 2022-08-19 百时美施贵宝公司 免疫调节剂
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WO2021202501A1 (en) 2020-03-30 2021-10-07 Bristol-Myers Squibb Company Immunomodulators
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Also Published As

Publication number Publication date
PT3458111T (pt) 2021-04-09
KR20190009330A (ko) 2019-01-28
EP3458111B1 (en) 2021-03-03
SG11201810177VA (en) 2018-12-28
IL262962A (en) 2018-12-31
EA201892635A1 (ru) 2019-04-30
JP6953444B2 (ja) 2021-10-27
WO2017201111A1 (en) 2017-11-23
AU2017268291A1 (en) 2019-01-17
RS61742B1 (sr) 2021-05-31
SI3458111T1 (sl) 2021-07-30
EP3458111A1 (en) 2019-03-27
EA038019B1 (ru) 2021-06-23
HRP20210644T1 (hr) 2021-05-28
MX2018014028A (es) 2019-04-04
CY1124241T1 (el) 2022-07-22
BR112018073642A2 (pt) 2019-02-26
SMT202100238T1 (it) 2021-05-07
CN109414514B (zh) 2022-03-11
CA3024844A1 (en) 2017-11-23
HUE054306T2 (hu) 2021-08-30
JP2019520328A (ja) 2019-07-18
HRP20210644T8 (hr) 2021-06-25
US20190117801A1 (en) 2019-04-25
MA53402A (fr) 2021-06-02
PL3458111T3 (pl) 2021-06-28
ES2864091T3 (es) 2021-10-13
DK3458111T3 (da) 2021-04-26
US11103605B2 (en) 2021-08-31
KR102378288B1 (ko) 2022-03-23
IL262962B (en) 2020-04-30
EP3827849A1 (en) 2021-06-02
LT3458111T (lt) 2021-05-25
US20210386876A1 (en) 2021-12-16
CN109414514A (zh) 2019-03-01

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