MA53402A - Immunomodulateurs pour l'imagerie tep - Google Patents

Immunomodulateurs pour l'imagerie tep

Info

Publication number
MA53402A
MA53402A MA053402A MA53402A MA53402A MA 53402 A MA53402 A MA 53402A MA 053402 A MA053402 A MA 053402A MA 53402 A MA53402 A MA 53402A MA 53402 A MA53402 A MA 53402A
Authority
MA
Morocco
Prior art keywords
immunomodulators
pet imaging
pet
imaging
Prior art date
Application number
MA053402A
Other languages
English (en)
French (fr)
Inventor
Kenneth M Boy
David J Donnelly
Joonyoung Kim
Adrienne Pena
Yunhui Zhang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MA53402A publication Critical patent/MA53402A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computed tomography [CT]
    • A61B6/037Emission tomography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/12Arrangements for detecting or locating foreign bodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA053402A 2016-05-19 2017-05-17 Immunomodulateurs pour l'imagerie tep MA53402A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662338872P 2016-05-19 2016-05-19

Publications (1)

Publication Number Publication Date
MA53402A true MA53402A (fr) 2021-06-02

Family

ID=59021563

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053402A MA53402A (fr) 2016-05-19 2017-05-17 Immunomodulateurs pour l'imagerie tep

Country Status (25)

Country Link
US (2) US11103605B2 (cg-RX-API-DMAC7.html)
EP (2) EP3827849A1 (cg-RX-API-DMAC7.html)
JP (1) JP6953444B2 (cg-RX-API-DMAC7.html)
KR (1) KR102378288B1 (cg-RX-API-DMAC7.html)
CN (1) CN109414514B (cg-RX-API-DMAC7.html)
AU (1) AU2017268291B2 (cg-RX-API-DMAC7.html)
BR (1) BR112018073642A2 (cg-RX-API-DMAC7.html)
CA (1) CA3024844A1 (cg-RX-API-DMAC7.html)
CY (1) CY1124241T1 (cg-RX-API-DMAC7.html)
DK (1) DK3458111T3 (cg-RX-API-DMAC7.html)
EA (1) EA038019B1 (cg-RX-API-DMAC7.html)
ES (1) ES2864091T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20210644T8 (cg-RX-API-DMAC7.html)
HU (1) HUE054306T2 (cg-RX-API-DMAC7.html)
IL (1) IL262962B (cg-RX-API-DMAC7.html)
LT (1) LT3458111T (cg-RX-API-DMAC7.html)
MA (1) MA53402A (cg-RX-API-DMAC7.html)
MX (1) MX2018014028A (cg-RX-API-DMAC7.html)
PL (1) PL3458111T3 (cg-RX-API-DMAC7.html)
PT (1) PT3458111T (cg-RX-API-DMAC7.html)
RS (1) RS61742B1 (cg-RX-API-DMAC7.html)
SG (1) SG11201810177VA (cg-RX-API-DMAC7.html)
SI (1) SI3458111T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202100238T1 (cg-RX-API-DMAC7.html)
WO (1) WO2017201111A1 (cg-RX-API-DMAC7.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9856292B2 (en) 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
US10143746B2 (en) 2016-03-04 2018-12-04 Bristol-Myers Squibb Company Immunomodulators
US10358463B2 (en) 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
WO2018048882A1 (en) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
US10736976B2 (en) 2016-12-01 2020-08-11 Regeneron Pharmaceuticals, Inc. Radiolabeled anti-PD-L1 antibodies for immuno-PET imaging
EP3558395A4 (en) 2016-12-23 2020-08-12 The Johns Hopkins University IMAGING OF TUMOR CELLS AND IMMUNE CELLS BASED ON PD-L1 EXPRESSION
BR112019016336A2 (pt) 2017-02-10 2020-03-31 Regeneron Pharmaceuticals, Inc. Conjugado de anticorpo radiorrotulado, método para imageamento de um tecido que expressa lag3 e para tratar um tumor, e, composto.
KR102735038B1 (ko) 2017-06-23 2024-11-28 브리스톨-마이어스 스큅 컴퍼니 Pd-1의 길항제로서 작용하는 면역조정제
MY197688A (en) 2017-07-24 2023-07-05 Regeneron Pharma Anti-cd8 antibodies and uses thereof
EP3692053A1 (en) 2017-10-03 2020-08-12 Bristol-Myers Squibb Company Immunomodulators
CN110504017B (zh) * 2019-07-30 2022-06-10 哈尔滨医科大学 一种示踪剂的制备和使用方法
CN114929728A (zh) 2020-01-06 2022-08-19 百时美施贵宝公司 免疫调节剂
EP4121442A1 (en) * 2020-03-16 2023-01-25 Bristol-Myers Squibb Company Immunomodulators
WO2021202501A1 (en) 2020-03-30 2021-10-07 Bristol-Myers Squibb Company Immunomodulators
US12159403B2 (en) * 2021-06-18 2024-12-03 The United States Government As Represented By The Department Of Veteran Affairs Combination of features from biopsies and scans to predict prognosis in SCLC
EP4634205A2 (en) * 2022-12-12 2025-10-22 Merck Sharp & Dohme LLC Cyclic peptides as pet imaging agents of granzyme b

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5374548A (en) 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
MX9203291A (es) 1985-06-26 1992-08-01 Liposome Co Inc Metodo para acoplamiento de liposomas.
US5101827A (en) 1985-07-05 1992-04-07 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US5776093A (en) 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
US4735210A (en) 1985-07-05 1988-04-05 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US5328679A (en) 1988-04-01 1994-07-12 Immunomedics, Inc. Methods for technetium/rhenium labeling of proteins
US5128119A (en) 1989-06-12 1992-07-07 Immunomedics, Inc. Methods for technetium/rhenium labeling of f(ab1)2 fragments
US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
IL113610A0 (en) 1994-06-03 1995-08-31 Immunomedics Inc A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
US5746996A (en) 1994-06-03 1998-05-05 Immunomedics, Inc. Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US5753206A (en) 1995-06-07 1998-05-19 Immunomedics, Inc. Radiometal-binding analogues of luteinizing hormone releasing hormone
ATE365562T1 (de) 1996-05-03 2007-07-15 Immunomedics Inc Zielgerichtete kombinations-immuntherapie für krebs
ATE380038T1 (de) 1996-07-12 2007-12-15 Immunomedics Inc Radiometall-bindende peptide analoge
US6277818B1 (en) 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
CA2302360C (en) 1997-09-03 2005-11-15 Immunomedics, Inc. Fluorination of proteins and peptides for f-18 positron emission tomography
US9090668B2 (en) 2007-03-26 2015-07-28 The University Of Tokyo Process for synthesizing cyclic peptide compound
EP2328919A2 (en) 2008-08-25 2011-06-08 Amplimmune, Inc. Pd-i antagonists and methods for treating infectious disease
US8907053B2 (en) 2010-06-25 2014-12-09 Aurigene Discovery Technologies Limited Immunosuppression modulating compounds
JP5818237B2 (ja) 2010-09-09 2015-11-18 国立大学法人 東京大学 N−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法
US10195578B2 (en) 2010-12-03 2019-02-05 The University Of Tokyo Peptide library production method, peptide library, and screening method
WO2012168944A1 (en) 2011-06-08 2012-12-13 Aurigene Discovery Technologies Limited Therapeutic compounds for immunomodulation
WO2013010573A1 (en) * 2011-07-18 2013-01-24 Universitaet Muenster Compounds with matrix-metalloproteinase inhibitory activity
MX2014011353A (es) 2012-03-29 2014-12-05 Aurigene Discovery Tech Ltd Inmunomodulacion de compuestos ciclicos del bucle bc de muerte celular programada (pd1) humana.
MX355396B (es) 2012-06-06 2018-04-18 Polyphor Ag Peptido - mimeticos de la horquilla beta.
JP2013253842A (ja) 2012-06-06 2013-12-19 Univ Of Tokyo pH依存的に標的分子に結合するペプチドのスクリーニング方法
MY176706A (en) 2013-03-15 2020-08-19 Genentech Inc Biomarkers and methods of treating pd-1 and pd-l1 related conditions
US9308236B2 (en) * 2013-03-15 2016-04-12 Bristol-Myers Squibb Company Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
HUE039012T2 (hu) 2013-09-06 2018-12-28 Aurigene Discovery Tech Ltd Gyûrûs peptidomimetikus vegyületek, mint immunomodulátorok
WO2015044900A1 (en) 2013-09-27 2015-04-02 Aurigene Discovery Technologies Limited Therapeutic immunomodulating compounds
WO2016039749A1 (en) 2014-09-11 2016-03-17 Bristol-Myers Squibb Company Macrocyclic inhibitors of the pd-1/pd-l1 and cd80 (b7-1)/pd-li protein/protein interactions
US9732119B2 (en) 2014-10-10 2017-08-15 Bristol-Myers Squibb Company Immunomodulators
US9856292B2 (en) * 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
EA037590B1 (ru) * 2014-11-25 2021-04-19 Бристол-Майерс Сквибб Компани Связывающиеся с pd-l1 полипептиды на основе 10fn3 домена для визуализации
CA2968961A1 (en) 2014-11-25 2016-06-02 Bristol-Myers Squibb Company Methods and compositions for 18f-radiolabeling of biologics
US9861680B2 (en) 2014-12-18 2018-01-09 Bristol-Myers Squibb Company Immunomodulators
US9944678B2 (en) 2014-12-19 2018-04-17 Bristol-Myers Squibb Company Immunomodulators
US20160222060A1 (en) 2015-02-04 2016-08-04 Bristol-Myers Squibb Company Immunomodulators
US9809625B2 (en) 2015-03-18 2017-11-07 Bristol-Myers Squibb Company Immunomodulators
US10143746B2 (en) 2016-03-04 2018-12-04 Bristol-Myers Squibb Company Immunomodulators
US10358463B2 (en) 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
US10994033B2 (en) 2016-06-01 2021-05-04 Bristol-Myers Squibb Company Imaging methods using 18F-radiolabeled biologics
KR102526034B1 (ko) 2016-11-07 2023-04-25 브리스톨-마이어스 스큅 컴퍼니 면역조정제
KR102735038B1 (ko) 2017-06-23 2024-11-28 브리스톨-마이어스 스큅 컴퍼니 Pd-1의 길항제로서 작용하는 면역조정제
EP3692053A1 (en) 2017-10-03 2020-08-12 Bristol-Myers Squibb Company Immunomodulators

Also Published As

Publication number Publication date
PT3458111T (pt) 2021-04-09
KR20190009330A (ko) 2019-01-28
EP3458111B1 (en) 2021-03-03
AU2017268291B2 (en) 2022-09-29
SG11201810177VA (en) 2018-12-28
IL262962A (en) 2018-12-31
EA201892635A1 (ru) 2019-04-30
JP6953444B2 (ja) 2021-10-27
WO2017201111A1 (en) 2017-11-23
AU2017268291A1 (en) 2019-01-17
RS61742B1 (sr) 2021-05-31
SI3458111T1 (sl) 2021-07-30
EP3458111A1 (en) 2019-03-27
EA038019B1 (ru) 2021-06-23
HRP20210644T1 (hr) 2021-05-28
MX2018014028A (es) 2019-04-04
CY1124241T1 (el) 2022-07-22
BR112018073642A2 (pt) 2019-02-26
SMT202100238T1 (it) 2021-05-07
CN109414514B (zh) 2022-03-11
CA3024844A1 (en) 2017-11-23
HUE054306T2 (hu) 2021-08-30
JP2019520328A (ja) 2019-07-18
HRP20210644T8 (hr) 2021-06-25
US20190117801A1 (en) 2019-04-25
PL3458111T3 (pl) 2021-06-28
ES2864091T3 (es) 2021-10-13
DK3458111T3 (da) 2021-04-26
US11103605B2 (en) 2021-08-31
KR102378288B1 (ko) 2022-03-23
IL262962B (en) 2020-04-30
EP3827849A1 (en) 2021-06-02
LT3458111T (lt) 2021-05-25
US20210386876A1 (en) 2021-12-16
CN109414514A (zh) 2019-03-01

Similar Documents

Publication Publication Date Title
MA53402A (fr) Immunomodulateurs pour l'imagerie tep
EP3393911A4 (en) AUTONOMOUS ANDOCKING STATION FOR DRONES
GB2547703B (en) Pet Fountains
EP3347458A4 (en) MULTI TRANSGENIC PIG FOR XENOTRANSPLANTATION
EP3630078A4 (en) CHEMOEMBOLIZING AGENTS
EP3379317A4 (en) IMAGING LENS
EP3519028A4 (en) JOCH FOR HEADGEAR
EP3627918C0 (en) Paging extension for enhanced coverage global system for mobile (ec-gsm)
EP3595438A4 (en) HORSE BOOTS
EP3504982A4 (en) FOOD PELLETS FOR Ruminants
EP3204028A4 (en) SYNERGISTIC COMPOSITION FOR OSTEOARTHRITIS
EP3338446A4 (en) IMAGE PROJECTIONS
EP3408731A4 (en) INTERACTION MODES FOR OBJECT DEVICE INTERACTIONS
FR3020758B1 (fr) Composition pour ameliorer l'hygiene buco-dentaire
EP3456183A4 (en) ARTICLE FOR PET CARE
EP3405864A4 (en) SPOOFING CPUID FOR DOWNWARD COMPATIBILITY
MA42525A (fr) Véhicule autonome pour repousser du fourrage
FR3018897B3 (fr) Structure lineaire encastrable pour l'illumination
EP3440943A4 (en) FOOD FOR WATER LIFE
EP3511961A4 (en) TRANSFORMER FOR VEHICLES
EP3347604A4 (en) MECHANISM FOR LOCKING A CLASP LOCK
FR3057736B3 (fr) Les coussins pour animaux familiers
EP3473445A4 (en) PAD PRINTING MACHINE
FR3048597B1 (fr) Drap-housse pour matelas
EP3426309A4 (en) RADIOLIGANDS FOR MYELIN