MA53402A - Immunomodulateurs pour l'imagerie tep - Google Patents

Immunomodulateurs pour l'imagerie tep

Info

Publication number
MA53402A
MA53402A MA053402A MA53402A MA53402A MA 53402 A MA53402 A MA 53402A MA 053402 A MA053402 A MA 053402A MA 53402 A MA53402 A MA 53402A MA 53402 A MA53402 A MA 53402A
Authority
MA
Morocco
Prior art keywords
immunomodulators
pet imaging
pet
imaging
Prior art date
Application number
MA053402A
Other languages
English (en)
Inventor
Kenneth M Boy
David J Donnelly
Joonyoung Kim
Adrienne Pena
Yunhui Zhang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MA53402A publication Critical patent/MA53402A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/037—Emission tomography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/12—Arrangements for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA053402A 2016-05-19 2017-05-17 Immunomodulateurs pour l'imagerie tep MA53402A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662338872P 2016-05-19 2016-05-19

Publications (1)

Publication Number Publication Date
MA53402A true MA53402A (fr) 2021-06-02

Family

ID=59021563

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053402A MA53402A (fr) 2016-05-19 2017-05-17 Immunomodulateurs pour l'imagerie tep

Country Status (24)

Country Link
US (2) US11103605B2 (fr)
EP (2) EP3458111B1 (fr)
JP (1) JP6953444B2 (fr)
KR (1) KR102378288B1 (fr)
CN (1) CN109414514B (fr)
AU (1) AU2017268291B2 (fr)
BR (1) BR112018073642A2 (fr)
CA (1) CA3024844A1 (fr)
CY (1) CY1124241T1 (fr)
DK (1) DK3458111T3 (fr)
EA (1) EA038019B1 (fr)
ES (1) ES2864091T3 (fr)
HR (1) HRP20210644T8 (fr)
HU (1) HUE054306T2 (fr)
IL (1) IL262962B (fr)
LT (1) LT3458111T (fr)
MA (1) MA53402A (fr)
MX (1) MX2018014028A (fr)
PL (1) PL3458111T3 (fr)
PT (1) PT3458111T (fr)
RS (1) RS61742B1 (fr)
SG (1) SG11201810177VA (fr)
SI (1) SI3458111T1 (fr)
WO (1) WO2017201111A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9856292B2 (en) 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
US10143746B2 (en) 2016-03-04 2018-12-04 Bristol-Myers Squibb Company Immunomodulators
US10358463B2 (en) 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
WO2018048882A1 (fr) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Composition d'agent d'imagerie par tomographie par imagerie de positrons et méthode pour infection bactérienne
AU2017367734A1 (en) 2016-12-01 2019-06-20 Regeneron Pharmaceuticals, Inc. Radiolabeled anti-PD-l1 antibodies for immuno-PET imaging
WO2018119313A1 (fr) 2016-12-23 2018-06-28 The Johns Hopkins University Imagerie de cellules tumorales et de cellules immunitaires reposant sur l'expression de pd-l1
EA201991673A1 (ru) 2017-02-10 2020-01-17 Регенерон Фармасьютикалз, Инк. Меченные радиоактивным изотопом антитела к lag3 для иммуно-пэт-визуализации
CN110997698B (zh) 2017-06-23 2023-12-26 百时美施贵宝公司 充当pd-1拮抗剂的免疫调节剂
US10730944B2 (en) 2017-07-24 2020-08-04 Regeneron Pharmaceuticals, Inc. Anti-CD8 antibodies and uses thereof
CN111051332B (zh) 2017-10-03 2024-09-06 百时美施贵宝公司 免疫调节剂
CN110504017B (zh) * 2019-07-30 2022-06-10 哈尔滨医科大学 一种示踪剂的制备和使用方法
CN115485288A (zh) * 2020-03-16 2022-12-16 百时美施贵宝公司 免疫调节剂
US20220405917A1 (en) * 2021-06-18 2022-12-22 Case Western Reserve University Combination of features from biopsies and scans to predict prognosis in sclc
WO2024129479A2 (fr) * 2022-12-12 2024-06-20 Merck Sharp & Dohme Llc Peptides cycliques utilisés en tant qu'agents d'imagerie tep de granzyme b

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5374548A (en) 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
MX9203291A (es) 1985-06-26 1992-08-01 Liposome Co Inc Metodo para acoplamiento de liposomas.
US5776093A (en) 1985-07-05 1998-07-07 Immunomedics, Inc. Method for imaging and treating organs and tissues
US5101827A (en) 1985-07-05 1992-04-07 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US4735210A (en) 1985-07-05 1988-04-05 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US5128119A (en) 1989-06-12 1992-07-07 Immunomedics, Inc. Methods for technetium/rhenium labeling of f(ab1)2 fragments
US5328679A (en) 1988-04-01 1994-07-12 Immunomedics, Inc. Methods for technetium/rhenium labeling of proteins
US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
IL113610A0 (en) 1994-06-03 1995-08-31 Immunomedics Inc A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
US5746996A (en) 1994-06-03 1998-05-05 Immunomedics, Inc. Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
US5753206A (en) 1995-06-07 1998-05-19 Immunomedics, Inc. Radiometal-binding analogues of luteinizing hormone releasing hormone
US5869451A (en) 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
DE69737867T2 (de) 1996-05-03 2007-10-18 Immunomedics, Inc. Zielgerichtete kombinations-immuntherapie für krebs
US6126916A (en) 1996-07-12 2000-10-03 Immunomedics, Inc. Radiometal-binding peptide analogues
US6277818B1 (en) 1998-10-29 2001-08-21 Angstrom Pharmaceuticals, Inc. Cyclic peptide ligands that target urokinase plasminogen activator receptor
JP3992923B2 (ja) 1997-09-03 2007-10-17 イムノメディクス， インコーポレイテッド Ｆ−１８陽電子放出トモグラフィー用のタン白及びペプチドのフッ素化方法
EP2990411B1 (fr) 2007-03-26 2017-05-03 The University of Tokyo Procede pour synthetiser un compose peptidique cyclique
JP2012500855A (ja) 2008-08-25 2012-01-12 アンプリミューン、インコーポレーテッド Ｐｄ−１アンタゴニストおよび感染性疾患を処置するための方法
US8907053B2 (en) 2010-06-25 2014-12-09 Aurigene Discovery Technologies Limited Immunosuppression modulating compounds
JP5818237B2 (ja) 2010-09-09 2015-11-18 国立大学法人 東京大学 Ｎ−メチルアミノ酸およびその他の特殊アミノ酸を含む特殊ペプチド化合物ライブラリーの翻訳構築と活性種探索法
EP2647720B1 (fr) 2010-12-03 2019-06-19 The University of Tokyo Procédé de production d'une banque de peptides, banque de peptides et procédé de criblage
WO2012168944A1 (fr) 2011-06-08 2012-12-13 Aurigene Discovery Technologies Limited Composés thérapeutiques pour une immunomodulation
WO2013010573A1 (fr) * 2011-07-18 2013-01-24 Universitaet Muenster Composés avec activité inhibitrice de métalloprotéinase de matrice
JP2015512910A (ja) 2012-03-29 2015-04-30 オーリジーン ディスカバリー テクノロジーズ リミテッドＡｕｒｉｇｅｎｅ Ｄｉｓｃｏｖｅｒｙ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｉｍｉｔｅｄ ヒトｐｄ１のｂｃループに由来する免疫調節性環状化合物
JP2013253842A (ja) 2012-06-06 2013-12-19 Univ Of Tokyo ｐＨ依存的に標的分子に結合するペプチドのスクリーニング方法
IN2014KN02752A (fr) 2012-06-06 2015-05-08 Polyphor Ag
US9308236B2 (en) 2013-03-15 2016-04-12 Bristol-Myers Squibb Company Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
KR20230070054A (ko) 2013-03-15 2023-05-19 제넨테크, 인크. Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
LT3041468T (lt) 2013-09-06 2018-10-25 Aurigene Discovery Technologies Limited Cikliniai peptidomimetiniai junginiai kaip imunomoduliatoriai
WO2015044900A1 (fr) 2013-09-27 2015-04-02 Aurigene Discovery Technologies Limited Composés immunomodulateurs thérapeutiques
AU2014405919B2 (en) 2014-09-11 2020-02-20 Bristol-Myers Squibb Company Macrocyclic inhibitors of the PD-1/PD-L1 and CD80 (B7-1)/PD-Li protein/protein interactions
US9732119B2 (en) 2014-10-10 2017-08-15 Bristol-Myers Squibb Company Immunomodulators
US9856292B2 (en) * 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
JP6701217B2 (ja) 2014-11-25 2020-05-27 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 生物学的製剤の１８ｆ−放射性標識方法および組成物
EP3702367B1 (fr) * 2014-11-25 2024-05-15 Bristol-Myers Squibb Company Nouveaux polypeptides de liaison pd-l1 pour imagerie
US9861680B2 (en) 2014-12-18 2018-01-09 Bristol-Myers Squibb Company Immunomodulators
US9944678B2 (en) 2014-12-19 2018-04-17 Bristol-Myers Squibb Company Immunomodulators
US20160222060A1 (en) 2015-02-04 2016-08-04 Bristol-Myers Squibb Company Immunomodulators
US9809625B2 (en) 2015-03-18 2017-11-07 Bristol-Myers Squibb Company Immunomodulators
US10143746B2 (en) 2016-03-04 2018-12-04 Bristol-Myers Squibb Company Immunomodulators
US10358463B2 (en) 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
US10994033B2 (en) 2016-06-01 2021-05-04 Bristol-Myers Squibb Company Imaging methods using 18F-radiolabeled biologics
CN110267971B (zh) 2016-11-07 2023-12-19 百时美施贵宝公司 免疫调节剂
CN110997698B (zh) 2017-06-23 2023-12-26 百时美施贵宝公司 充当pd-1拮抗剂的免疫调节剂
CN111051332B (zh) 2017-10-03 2024-09-06 百时美施贵宝公司 免疫调节剂

Also Published As

Publication number Publication date
JP2019520328A (ja) 2019-07-18
PT3458111T (pt) 2021-04-09
BR112018073642A2 (pt) 2019-02-26
MX2018014028A (es) 2019-04-04
WO2017201111A1 (fr) 2017-11-23
RS61742B1 (sr) 2021-05-31
LT3458111T (lt) 2021-05-25
US20210386876A1 (en) 2021-12-16
US20190117801A1 (en) 2019-04-25
HUE054306T2 (hu) 2021-08-30
PL3458111T3 (pl) 2021-06-28
AU2017268291B2 (en) 2022-09-29
EP3827849A1 (fr) 2021-06-02
JP6953444B2 (ja) 2021-10-27
ES2864091T3 (es) 2021-10-13
US11103605B2 (en) 2021-08-31
HRP20210644T1 (hr) 2021-05-28
CN109414514B (zh) 2022-03-11
AU2017268291A1 (en) 2019-01-17
SG11201810177VA (en) 2018-12-28
EA038019B1 (ru) 2021-06-23
CN109414514A (zh) 2019-03-01
HRP20210644T8 (hr) 2021-06-25
EP3458111B1 (fr) 2021-03-03
EP3458111A1 (fr) 2019-03-27
DK3458111T3 (da) 2021-04-26
KR20190009330A (ko) 2019-01-28
IL262962A (en) 2018-12-31
CY1124241T1 (el) 2022-07-22
IL262962B (en) 2020-04-30
SI3458111T1 (sl) 2021-07-30
CA3024844A1 (fr) 2017-11-23
EA201892635A1 (ru) 2019-04-30
KR102378288B1 (ko) 2022-03-23

Similar Documents

Publication Publication Date Title
MA53402A (fr) Immunomodulateurs pour l'imagerie tep
GB2547703B (en) Pet Fountains
MA46652A (fr) Polythérapie pour l'inhibition de c3
FR3016407B1 (fr) Boitier d'entrainement pour equipements
FR3025157B1 (fr) Systeme d'ouvrant pour vehicule
FR3020758B1 (fr) Composition pour ameliorer l'hygiene buco-dentaire
FR3028076B1 (fr) Architecture logicielle pour systeme expert
MA42525A (fr) Véhicule autonome pour repousser du fourrage
FR3018897B3 (fr) Structure lineaire encastrable pour l'illumination
GB201618487D0 (en) Pet imaging system
FR3049441B1 (fr) Capsule multi-compartiments pour iontophorese
FR3023312B1 (fr) Poutrelle pour la realisation d'un plancher
FR3057736B3 (fr) Les coussins pour animaux familiers
FR3048597B1 (fr) Drap-housse pour matelas
FR3046351B1 (fr) Chariot- portoir pour brancard.
FR3049751B1 (fr) Perfectionnement pour accordeon
FR3028181B3 (fr) Raccord pour ventilation
FR3020383B3 (fr) Bourreuse manuelle pour bourrer une voie ferree
FR3018839B1 (fr) Boite d'attente pour armatures de liaison
FR3054422B1 (fr) Structure de sommier pour literie
DK3484528T3 (da) Tau-pet-billeddannelsesligander
FR3055785B3 (fr) Couvercle-passoire pour autocuiseur
IT201700084484A1 (it) Collare per animali domestici
UA34226S (uk) Водостічна труба
MA43954A (fr) Ligands d'imagerie tau-pet