RS58104B1 - Farmaceutske kombinacije za lečenje alchajmerove bolesti - Google Patents

Farmaceutske kombinacije za lečenje alchajmerove bolesti

Info

Publication number
RS58104B1
RS58104B1 RS20181571A RSP20181571A RS58104B1 RS 58104 B1 RS58104 B1 RS 58104B1 RS 20181571 A RS20181571 A RS 20181571A RS P20181571 A RSP20181571 A RS P20181571A RS 58104 B1 RS58104 B1 RS 58104B1
Authority
RS
Serbia
Prior art keywords
disease
pharmaceutical compositions
treating alzheimer
alzheimer
treating
Prior art date
Application number
RS20181571A
Other languages
English (en)
Inventor
Ellen Schmidt
Johan Areberg
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49118521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS58104(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of RS58104B1 publication Critical patent/RS58104B1/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RS20181571A 2012-09-09 2013-09-06 Farmaceutske kombinacije za lečenje alchajmerove bolesti RS58104B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261698664P 2012-09-09 2012-09-09
US201361782084P 2013-03-14 2013-03-14
PCT/EP2013/068516 WO2014037532A1 (en) 2012-09-09 2013-09-06 Methods of treating alzheimer's disease and pharmaceutical compositions thereof
EP13759195.4A EP2892563B1 (en) 2012-09-09 2013-09-06 Pharmaceutical compositions for treating alzheimer's disease

Publications (1)

Publication Number Publication Date
RS58104B1 true RS58104B1 (sr) 2019-02-28

Family

ID=49118521

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20181571A RS58104B1 (sr) 2012-09-09 2013-09-06 Farmaceutske kombinacije za lečenje alchajmerove bolesti

Country Status (33)

Country Link
US (4) US9375418B2 (sr)
EP (1) EP2892563B1 (sr)
JP (2) JP6693744B2 (sr)
KR (2) KR102342127B1 (sr)
CN (1) CN104619344A (sr)
AP (1) AP2015008306A0 (sr)
AU (1) AU2013311573B2 (sr)
BR (1) BR112015005117B1 (sr)
CA (1) CA2883751C (sr)
CL (1) CL2015000578A1 (sr)
CY (1) CY1121062T1 (sr)
DK (1) DK2892563T3 (sr)
EA (1) EA030448B1 (sr)
ES (1) ES2703630T3 (sr)
GE (1) GEP201706776B (sr)
HK (1) HK1212217A1 (sr)
HR (1) HRP20182069T1 (sr)
IL (1) IL237369B (sr)
JO (1) JO3459B1 (sr)
LT (1) LT2892563T (sr)
MX (1) MX368305B (sr)
MY (1) MY182539A (sr)
NI (1) NI201500031A (sr)
NZ (1) NZ630589A (sr)
PL (1) PL2892563T3 (sr)
PT (1) PT2892563T (sr)
RS (1) RS58104B1 (sr)
RU (1) RU2675786C2 (sr)
SG (1) SG11201501774QA (sr)
SI (1) SI2892563T1 (sr)
TN (1) TN2015000076A1 (sr)
TW (1) TWI632909B (sr)
WO (1) WO2014037532A1 (sr)

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US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
JO3459B1 (ar) * 2012-09-09 2020-07-05 H Lundbeck As تركيبات صيدلانية لعلاج مرض الزهايمر
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JP6294953B2 (ja) 2013-03-14 2018-03-14 ヤンセン ファーマシューティカ エヌ.ベー. P2x7調節物質
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JO3509B1 (ar) 2013-03-14 2020-07-05 Janssen Pharmaceutica Nv معدلات p2x7
JO3639B1 (ar) 2014-07-04 2020-08-27 H Lundbeck As صورة متعددة الشكل جديدة لـ n-[2-(6-فلورو-1h-إندول-3-يل)إيثيل]-3-(2،2،3،3-تترا فلورو بروبوكسي)بنزيل أمين هيدروكلوريد
JP6592510B2 (ja) 2014-09-12 2019-10-16 ヤンセン ファーマシューティカ エヌ.ベー. P2x7調節因子
UA118610C2 (uk) 2014-09-12 2019-02-11 Бьорінгер Інгельхайм Інтернаціональ Гмбх Спіроциклічні інгібітори катепсину c
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KR20180064373A (ko) 2015-07-15 2018-06-14 엑소반트 사이언시즈 게엠베하 신경퇴행성 질환과 관련된 환각의 예방 및 치료에 유용한 5-ht2a 세로토닌 수용체의 조절자로서의 다이아릴 및 아릴헤테로아릴 우레아 유도체
BR112017026928B1 (pt) * 2016-04-26 2023-04-11 H. Lundbeck A/S Uso de idalopirdina em combinação com um inibidor de acetilcolinesterase
US10864191B2 (en) * 2016-05-11 2020-12-15 H. Lundbeck A/S 5-HT6 receptor antagonists for use in the treatment of Alzheimer's disease with apathy as comorbidity
EA036347B1 (ru) 2016-05-18 2020-10-29 Сувен Лайф Сайенсиз Лимитед Комбинация чистых антагонистов 5-ht6 рецепторов с ингибиторами ацетилхолинэстеразы
CN106309436A (zh) * 2016-07-25 2017-01-11 宁波大学 可用作乙酰胆碱酯酶抑制剂的色胺衍生物及其用途
CN107118146B (zh) * 2017-04-13 2019-09-03 宁波大学 一种6-溴色胺衍生物及其制备方法和用途
WO2018215478A1 (en) * 2017-05-24 2018-11-29 H. Lundbeck A/S Combination of a 5-ht6 receptor antagonist and an acetylcholinesterase inhibitor for use in the treatment of alzheimer's disease in a patient subpopulation carrying apoe4 alleles
MA53721A (fr) 2018-09-28 2021-09-15 Janssen Pharmaceutica Nv Modulateurs de la monoacylglycérol lipase
TW202035409A (zh) 2018-09-28 2020-10-01 比利時商健生藥品公司 單醯基甘油脂肪酶調節劑
CN114555596A (zh) 2019-09-30 2022-05-27 詹森药业有限公司 放射性标记的mgl pet配体
NL2024431B1 (en) 2019-12-11 2021-09-07 Sulfateq Bv Compounds for treatment of alzheimer’s disease
BR112022019077A2 (pt) 2020-03-26 2022-12-27 Janssen Pharmaceutica Nv Moduladores da monoacilglicerol lipase

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Also Published As

Publication number Publication date
JO3459B1 (ar) 2020-07-05
RU2015107877A (ru) 2016-10-27
HK1212217A1 (en) 2016-06-10
KR20200137028A (ko) 2020-12-08
AU2013311573A1 (en) 2015-03-12
NZ630589A (en) 2015-12-24
TW201414474A (zh) 2014-04-16
LT2892563T (lt) 2019-01-10
EA030448B1 (ru) 2018-08-31
US9687473B2 (en) 2017-06-27
CY1121062T1 (el) 2019-12-11
US20160256437A1 (en) 2016-09-08
KR102342127B1 (ko) 2021-12-21
KR20150065680A (ko) 2015-06-15
MX2015002879A (es) 2015-07-06
RU2675786C2 (ru) 2018-12-25
ES2703630T3 (es) 2019-03-11
AP2015008306A0 (en) 2015-03-31
TWI632909B (zh) 2018-08-21
CA2883751C (en) 2020-11-24
MY182539A (en) 2021-01-25
IL237369B (en) 2018-11-29
CA2883751A1 (en) 2014-03-13
JP6693744B2 (ja) 2020-05-13
US20180071254A1 (en) 2018-03-15
JP2019059760A (ja) 2019-04-18
BR112015005117B1 (pt) 2022-06-21
JP2015528471A (ja) 2015-09-28
CL2015000578A1 (es) 2015-05-15
BR112015005117A2 (pt) 2017-07-04
GEP201706776B (en) 2017-11-27
EA201590353A1 (ru) 2016-03-31
SG11201501774QA (en) 2015-05-28
DK2892563T3 (en) 2019-01-21
US9375418B2 (en) 2016-06-28
WO2014037532A1 (en) 2014-03-13
EP2892563A1 (en) 2015-07-15
US20140073681A1 (en) 2014-03-13
AU2013311573A8 (en) 2015-03-19
CN104619344A (zh) 2015-05-13
AU2013311573B2 (en) 2017-10-12
TN2015000076A1 (en) 2016-06-29
US9789085B2 (en) 2017-10-17
HRP20182069T1 (hr) 2019-02-08
PT2892563T (pt) 2019-01-10
MX368305B (es) 2019-09-27
US10660878B2 (en) 2020-05-26
US20160354343A1 (en) 2016-12-08
PL2892563T3 (pl) 2019-04-30
SI2892563T1 (sl) 2019-02-28
EP2892563B1 (en) 2018-11-14
IL237369A0 (en) 2015-04-30
NI201500031A (es) 2016-02-15

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