RO83053B - Procedeu pentru prepararea unor derivati de fenetanolamina - Google Patents
Procedeu pentru prepararea unor derivati de fenetanolaminaInfo
- Publication number
- RO83053B RO83053B RO105066A RO10506679A RO83053B RO 83053 B RO83053 B RO 83053B RO 105066 A RO105066 A RO 105066A RO 10506679 A RO10506679 A RO 10506679A RO 83053 B RO83053 B RO 83053B
- Authority
- RO
- Romania
- Prior art keywords
- general formula
- preparation
- derivatives
- phenetanolamine
- methanesulfonylamino
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 hydroxy, aminocarbonyl Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- AWMVMTVKBNGEAK-UHFFFAOYSA-N Styrene oxide Chemical class C1OC1C1=CC=CC=C1 AWMVMTVKBNGEAK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004458 methylaminocarbonyl group Chemical group [H]N(C(*)=O)C([H])([H])[H] 0.000 abstract 1
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical class NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92166878A | 1978-07-03 | 1978-07-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO83053A RO83053A (ro) | 1984-02-21 |
| RO83053B true RO83053B (ro) | 1984-02-28 |
Family
ID=25445786
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO105066A RO83053B (ro) | 1978-07-03 | 1979-07-02 | Procedeu pentru prepararea unor derivati de fenetanolamina |
| RO7998011A RO77731A (ro) | 1978-07-03 | 1979-07-02 | Procedeu pentru prepararea unor derivati de fenetanolamina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO7998011A RO77731A (ro) | 1978-07-03 | 1979-07-02 | Procedeu pentru prepararea unor derivati de fenetanolamina |
Country Status (33)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0006735B1 (en) * | 1978-06-28 | 1983-06-15 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| NL8105170A (nl) * | 1980-12-10 | 1982-07-01 | Thomae Gmbh Dr K | Nieuwe fenylalkylaminen, werkwijze ter bereiding daarvan en de toepassing daarvan als geneesmiddelen. |
| EP0068669A1 (en) * | 1981-06-20 | 1983-01-05 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
| CA1219865A (en) * | 1982-05-14 | 1987-03-31 | Leo Alig | Aziridine phenethanolamine derivatives |
| CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
| EP0102213A1 (en) * | 1982-08-21 | 1984-03-07 | Beecham Group Plc | Ethanolamine derivatives, pharmaceutical compositions containing them, and processes for preparing them |
| FI81713C (fi) * | 1983-01-31 | 1990-12-10 | Lilly Co Eli | Foerfarande och djurfoderpremix foer befraemjande av tillvaexten, foerbaettring av utnyttjandegraden av foder eller minskning av fetthalten i koett hos ett husdjur. |
| US4849453A (en) * | 1983-01-31 | 1989-07-18 | Eli Lilly And Company | Growth promotion |
| US4569801A (en) * | 1984-10-15 | 1986-02-11 | Eli Lilly And Company | Alkylsulfonamidophenylalkylamines |
| JPS62155213A (ja) * | 1985-12-20 | 1987-07-10 | イ−ライ・リリ−・アンド・カンパニ− | 腫瘍細胞崩壊剤 |
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| US5135955A (en) * | 1988-04-25 | 1992-08-04 | Eli Lilly And Company | Propanamine derivatives |
| US5051423A (en) * | 1988-07-13 | 1991-09-24 | Schering Ag | Derivatized alkanolamines as cardiovascular agents |
| US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| CN1073983C (zh) * | 1994-10-31 | 2001-10-31 | 中国科学院成都有机化学研究所 | 一种β－拟肾上腺素兴奋剂型饲料添加剂的合成方法 |
| US7547716B2 (en) | 2001-06-08 | 2009-06-16 | Institute Of Medicinal Molecular Design, Inc. | Sulfonamide derivatives |
| USD470271S1 (en) | 2001-12-21 | 2003-02-11 | Colgate Palmolive Company | Soap bar |
| TW200740779A (en) | 2005-07-22 | 2007-11-01 | Mitsubishi Pharma Corp | Intermediate compound for synthesizing pharmaceutical agent and production method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6610530A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1966-07-27 | 1968-01-29 | ||
| BE757005A (fr) * | 1969-10-02 | 1971-04-02 | Bristol Myers Co | Phenethanolamines substituees et procede pour leur preparation |
| US3801631A (en) * | 1972-02-16 | 1974-04-02 | Mead Johnson & Co | 2'-hydroxy-5'-(1-hydroxy-2-(2-methyl-1-phenyl-2-propylamino)ethyl)meth-anesulfonanilide and its salts |
-
1979
- 1979-06-26 IL IL57670A patent/IL57670A/xx unknown
- 1979-06-26 DK DK268579A patent/DK268579A/da not_active Application Discontinuation
- 1979-06-26 CA CA000330569A patent/CA1120058A/en not_active Expired
- 1979-06-27 EG EG386/79A patent/EG14400A/xx active
- 1979-06-27 PH PH22700A patent/PH15650A/en unknown
- 1979-06-27 NZ NZ190859A patent/NZ190859A/en unknown
- 1979-06-28 AU AU48488/79A patent/AU521744B2/en not_active Ceased
- 1979-06-28 PT PT69840A patent/PT69840A/pt unknown
- 1979-06-28 YU YU01548/79A patent/YU154879A/xx unknown
- 1979-06-29 FR FR7916992A patent/FR2430409A1/fr active Granted
- 1979-06-29 HU HU79EI866A patent/HU179170B/hu unknown
- 1979-07-02 BG BG045919A patent/BG40481A3/xx unknown
- 1979-07-02 GB GB7922953A patent/GB2028800B/en not_active Expired
- 1979-07-02 FI FI792080A patent/FI67686C/fi not_active IP Right Cessation
- 1979-07-02 JP JP8489479A patent/JPS559100A/ja active Granted
- 1979-07-02 EP EP79301282A patent/EP0007206B1/en not_active Expired
- 1979-07-02 RO RO105066A patent/RO83053B/ro unknown
- 1979-07-02 CS CS794630A patent/CS208661B2/cs unknown
- 1979-07-02 CS CS794630A patent/CS208660B2/cs unknown
- 1979-07-02 CH CH616479A patent/CH641759A5/fr not_active IP Right Cessation
- 1979-07-02 BG BG045920A patent/BG40482A3/xx unknown
- 1979-07-02 GR GR59488A patent/GR72546B/el unknown
- 1979-07-02 MX MX798145U patent/MX6160E/es unknown
- 1979-07-02 EP EP81109790A patent/EP0047536B1/en not_active Expired
- 1979-07-02 BE BE1/9443A patent/BE877392A/fr not_active IP Right Cessation
- 1979-07-02 SU SU792786502A patent/SU965351A3/ru active
- 1979-07-02 LU LU81456A patent/LU81456A1/xx unknown
- 1979-07-02 BG BG044165A patent/BG40480A3/xx unknown
- 1979-07-02 RO RO7998011A patent/RO77731A/ro unknown
- 1979-07-03 AT AT0463979A patent/AT370408B/de not_active IP Right Cessation
- 1979-07-03 ES ES482153A patent/ES482153A1/es not_active Expired
- 1979-07-03 PL PL1979222867A patent/PL123990B1/pl unknown
- 1979-07-03 AR AR277165A patent/AR222658A1/es active
- 1979-07-03 ZA ZA793295A patent/ZA793295B/xx unknown
- 1979-07-03 DD DD79214071A patent/DD144763A5/de unknown
- 1979-07-03 PL PL1979216810A patent/PL119783B1/pl unknown
- 1979-08-08 IE IE1231/79A patent/IE48436B1/en unknown
-
1980
- 1980-01-18 ES ES487847A patent/ES8101537A1/es not_active Expired
- 1980-09-12 SU SU802977044A patent/SU931102A3/ru active
- 1980-10-06 AR AR282776A patent/AR222727A1/es active
-
1985
- 1985-12-30 MY MY596/85A patent/MY8500596A/xx unknown
-
1987
- 1987-06-04 HK HK440/87A patent/HK44087A/xx unknown
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