RO82085B - PROCEDEU PENTRU PREPARAREA ACIZILOR ALCANOICI AVîND UN SUBSTITUENT ALFA- AROMATIC SAU A ESTERILOR ACESTORA - Google Patents

PROCEDEU PENTRU PREPARAREA ACIZILOR ALCANOICI AVîND UN SUBSTITUENT ALFA- AROMATIC SAU A ESTERILOR ACESTORA

Info

Publication number
RO82085B
RO82085B RO105287A RO10528781A RO82085B RO 82085 B RO82085 B RO 82085B RO 105287 A RO105287 A RO 105287A RO 10528781 A RO10528781 A RO 10528781A RO 82085 B RO82085 B RO 82085B
Authority
RO
Romania
Prior art keywords
alpha
esters
preparation
radical
general formula
Prior art date
Application number
RO105287A
Other languages
English (en)
Other versions
RO82085A (ro
Inventor
Genichi Tsuchihashi
Shuichi Mitamura
Kouji Kitajima
Original Assignee
Sagami Chemical Research Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27519313&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO82085(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP55125355A external-priority patent/JPS5750956A/ja
Priority claimed from JP55143042A external-priority patent/JPS5767535A/ja
Priority claimed from JP55157049A external-priority patent/JPS5798232A/ja
Priority claimed from JP1170081A external-priority patent/JPS57128661A/ja
Priority claimed from JP9097981A external-priority patent/JPS5810537A/ja
Application filed by Sagami Chemical Research Center filed Critical Sagami Chemical Research Center
Publication of RO82085B publication Critical patent/RO82085B/ro
Publication of RO82085A publication Critical patent/RO82085A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/307—Compounds having groups having acetal carbon atoms bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Prezenta inventie se refera la un procedeu de preparare a acizilor alfa-aromatic sau a esterilor acestora, cu formula generala I: (vezi formula) în care Ar reprezinta o grupa fenil, naftil sau tienil, eventula substituita si R1 reprezinta un atom de hidrogen sau o grupa alchil 1...5 atomi de carbon sau Ar si R1 împreuna cu atomul de carbon la care sunt legati pot forma un inel indanic, si R2 reprezinta un atom de hidrigen, un radical alchil sau un substituent hidroxialchil conform caruia un acetal de alfa-sulfoniloxi-acetona cu formula generala II: (vezi formula) în care R3 si R4, în mod independent unul de altul, reprezinta un radical alchilen, R5 reprezinta un radical alchil substituit sau nesubstituit sau un radical aromatic si Ar si R1 sunt definiti mai sus, este hidrolizat la o temperatura cuprinsa între temperatura de reflux si 250 degree C, hidroliza este facuta într-un solvent polar aprotic, în conditii neutre sau bazice, de preferinta în prezenta unei baze, fiind utilizata într-o cantitate cel putin egala cu 1 echivalent per mol din compusul cu formula II.
RO81105287A 1980-09-11 1981-09-11 Procedeu pentru prepararea acizilor alcanoici avind un substituent alfa aromatic sau esteric RO82085A (ro)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP55125355A JPS5750956A (en) 1980-09-11 1980-09-11 Alpha-sulfonyloxyalkanophenone acetal
JP55143042A JPS5767535A (en) 1980-10-15 1980-10-15 Preparation of alpha-aromatic group substituted alkanecarboxylic acid
JP55157049A JPS5798232A (en) 1980-11-10 1980-11-10 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal
JP1170081A JPS57128661A (en) 1981-01-30 1981-01-30 1-(4-substituted aminophenyl)-2-oxy-1-alkanone acetal
JP9097981A JPS5810537A (ja) 1981-06-15 1981-06-15 α−芳香族基置換アルカン酸類の製造方法

Publications (2)

Publication Number Publication Date
RO82085B true RO82085B (ro) 1983-06-30
RO82085A RO82085A (ro) 1983-07-07

Family

ID=27519313

Family Applications (3)

Application Number Title Priority Date Filing Date
RO81105287A RO82085A (ro) 1980-09-11 1981-09-11 Procedeu pentru prepararea acizilor alcanoici avind un substituent alfa aromatic sau esteric
RO110733A RO85818B (ro) 1980-09-11 1981-09-11 PROCEDEU PENTRU PREPARAREA ACIZILOR ALCANOICI SUBSTITUITI îN ALFA CU UN SUBSTITUENT AROMATIC SI A ESTERILOR ACESTORA
RO110734A RO86227B (ro) 1980-09-11 1981-09-11 Procedeu de preparare a unor acetali de alfa-sulfoniloxifenone substituite

Family Applications After (2)

Application Number Title Priority Date Filing Date
RO110733A RO85818B (ro) 1980-09-11 1981-09-11 PROCEDEU PENTRU PREPARAREA ACIZILOR ALCANOICI SUBSTITUITI îN ALFA CU UN SUBSTITUENT AROMATIC SI A ESTERILOR ACESTORA
RO110734A RO86227B (ro) 1980-09-11 1981-09-11 Procedeu de preparare a unor acetali de alfa-sulfoniloxifenone substituite

Country Status (22)

Country Link
EP (2) EP0048136B1 (ro)
AR (1) AR228067A1 (ro)
AU (1) AU599006B2 (ro)
CA (1) CA1186318A (ro)
DD (1) DD202866A5 (ro)
DE (1) DE3174810D1 (ro)
DK (3) DK161020C (ro)
FI (1) FI73195C (ro)
GR (1) GR75077B (ro)
HK (1) HK20589A (ro)
IE (1) IE53333B1 (ro)
IL (3) IL63791A0 (ro)
IN (1) IN155107B (ro)
MY (1) MY8700825A (ro)
NO (1) NO157616C (ro)
NZ (1) NZ198271A (ro)
PH (3) PH17798A (ro)
PL (1) PL133927B1 (ro)
PT (1) PT73624B (ro)
RO (3) RO82085A (ro)
SG (1) SG98187G (ro)
YU (2) YU43500B (ro)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2423863A (en) * 1940-11-16 1947-07-15 George F Wales Sheet metal compartment with shelf supports and method of manufacture
IL65629A (en) * 1981-04-30 1987-08-31 Syntex Pharma Int Preparation of alpha-arylalkanoic acids and esters and salts thereof
JPS5810525A (ja) * 1981-06-15 1983-01-21 Sagami Chem Res Center 光学活性な１−芳香族基置換−１−アルカノン類の製造方法
FI82680C (fi) * 1981-12-11 1991-04-10 Syntex Pharma Int Framstaellning av - arylalkansyror.
IT1173216B (it) * 1984-02-03 1987-06-18 Zambon Spa Processo per la preparazione di acidi alfa-idrossiaril-alcanoici
US4649213A (en) * 1984-04-14 1987-03-10 Kyowa Hakko Kogyo Co. Ltd. Process for producing an α-aromatic group substituted alkanoic acid derivative
IT1188181B (it) * 1985-07-31 1988-01-07 Zambon Spa Processo per la preparazione di acidi carbossilici otticamente attivi e relativi intermedi
JPS62263153A (ja) * 1986-05-28 1987-11-16 エフ・ホフマン―ラ　ロシユ　アーゲー カルバゾ−ル誘導体
IT1197800B (it) * 1986-08-01 1988-12-06 Zambon Spa Processo per la sintesi di acidi carbossilici
IT1240228B (it) * 1989-01-25 1993-11-27 Syntex Inc Preparazione di acidi alfa-metilarenacetici.
IT1251958B (it) * 1991-10-18 1995-05-27 Zambon Spa Processo per la dealogenazione di derivati del naftalene
US9226907B2 (en) 2008-02-01 2016-01-05 Abbvie Inc. Extended release hydrocodone acetaminophen and related methods and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1109200B (it) * 1979-02-20 1985-12-16 Montedison Spa Processo per la preparazione di esteri di acidi arilacetici da alfa-alo-alchilarilchetoni
IE50898B1 (en) * 1980-02-26 1986-08-06 Blaschim Spa Process for preparing esters of 2-(6'-methoxy-2'-naphthyl)-propionic acid via rearrangement of new ketals of 2-halo-1-(6'-methoxy-2'-naphthyl)-propan-1-one
IL65629A (en) * 1981-04-30 1987-08-31 Syntex Pharma Int Preparation of alpha-arylalkanoic acids and esters and salts thereof
FI82680C (fi) * 1981-12-11 1991-04-10 Syntex Pharma Int Framstaellning av - arylalkansyror.

Also Published As

Publication number Publication date
MY8700825A (en) 1987-12-31
EP0151702A2 (en) 1985-08-21
FI73195B (fi) 1987-05-29
RO85818B (ro) 1984-11-30
EP0048136B1 (en) 1986-06-11
PT73624A (pt) 1981-10-01
RO82085A (ro) 1983-07-07
YU45076B (en) 1991-08-31
DK55690A (da) 1990-03-02
RO86227B (ro) 1985-04-02
NO813088L (no) 1982-03-12
FI73195C (fi) 1987-09-10
DE3174810D1 (en) 1986-07-17
FI812820L (fi) 1982-03-12
PH21751A (en) 1988-02-18
PH17798A (en) 1984-12-13
IE53333B1 (en) 1988-10-26
IL74744A0 (en) 1985-06-30
DD202866A5 (de) 1983-10-05
PL133927B1 (en) 1985-07-31
IE812057L (en) 1982-03-11
EP0048136A3 (en) 1982-10-27
DK55690D0 (da) 1990-03-02
RO86227A (ro) 1985-03-15
EP0151702A3 (en) 1985-10-02
YU43500B (en) 1989-08-31
RO85818A (ro) 1984-11-25
DK163056C (da) 1992-06-15
DK55790D0 (da) 1990-03-02
IN155107B (ro) 1985-01-05
PL232991A1 (en) 1983-01-31
DK163179C (da) 1992-06-22
EP0151702B1 (en) 1987-11-25
YU228886A (en) 1988-02-29
YU216181A (en) 1983-12-31
DK55790A (da) 1990-03-02
NZ198271A (en) 1985-05-31
AU599006B2 (en) 1990-07-12
DK161020C (da) 1991-10-28
EP0048136A2 (en) 1982-03-24
DK163056B (da) 1992-01-13
IL63791A0 (en) 1981-12-31
PT73624B (pt) 1982-11-17
PH21746A (en) 1988-02-10
DK396581A (da) 1982-03-12
DK163179B (da) 1992-02-03
AU4588985A (en) 1986-01-02
AR228067A1 (es) 1983-01-14
IL74744A (en) 1986-02-28
CA1186318A (en) 1985-04-30
HK20589A (en) 1989-03-17
GR75077B (ro) 1984-07-13
DK161020B (da) 1991-05-21
SG98187G (en) 1993-02-19
NO157616C (no) 1988-04-20
NO157616B (no) 1988-01-11

Similar Documents

Publication Publication Date Title
RO82085B (ro) PROCEDEU PENTRU PREPARAREA ACIZILOR ALCANOICI AVîND UN SUBSTITUENT ALFA- AROMATIC SAU A ESTERILOR ACESTORA
DK135891D0 (da) 1h-imidazooe4,5-caaquinolin-4-chlorforbindelse
ES8202792A1 (es) Procedimiento para la preparacion de un agente para la de- teccion de enzimas esteroliticas y-o proteoliticas y subs- tratos apropiados
RO83311B (ro) Procedeu de preparare a unor saruri de monoester de acid fosforic
FI834730A (fi) 1-karboxialkanoylperhydro-indol-2- karboxylsyror och deras derivat.
ATE28208T1 (de) Pentaerythrit-spiro-bis-phosphitzusammensetzungen mit hydrolysebestaendigkeit.
ES8404318A1 (es) Procedimiento para la preparacion de un aducto de un diisocianato
ES529281A0 (es) Un procedimiento para preparar derivados de biciclooctano
ES8306999A1 (es) Procedimiento para preparar nuevos derivados de etenilimidazol.
ES8100238A1 (es) Un procedimiento para la preparacion de derivados del acido oxisustituido-ciclohexilacetico
ATE28749T1 (de) Verfahren zur herstellung von 3,4-dihydro-alpha- pyronen.
MY100575A (en) Microbicides
DE69202564T2 (de) Verfahren zur Herstellung von 1,3-Dioxan-4,6-Dionderivaten.
ES2010505B3 (es) Procedimiento de preparacion de acidos alcanoicos.
JPS6490184A (en) Pyridonecarboxylic acids
RO98498B1 (ro) Procedeu de preparare a derivatilor esteri propilenici ciclici ai acidului dihidripiridin-5-fosforic
DE3788369D1 (de) Verfahren zur Herstellung von Cephalosporinderivaten.
DE58907486D1 (de) Verfahren zur Herstellung von Halosilanen.
RO85311B1 (ro) Procedeu pentru obtinerea unui agent de blocare beta-adrenergica
AU5977980A (en) Aminodeoxyclavulanic acids