RO68380B - Procedeu pentru prepararea n-1-(3, 4-metilendioxifenil)-propil(2)-fenilpiperazine substituite - Google Patents
Procedeu pentru prepararea n-1-(3, 4-metilendioxifenil)-propil(2)-fenilpiperazine substituiteInfo
- Publication number
- RO68380B RO68380B RO83281A RO8328175A RO68380B RO 68380 B RO68380 B RO 68380B RO 83281 A RO83281 A RO 83281A RO 8328175 A RO8328175 A RO 8328175A RO 68380 B RO68380 B RO 68380B
- Authority
- RO
- Romania
- Prior art keywords
- phenylpiperazines
- propyl
- methylendioxyphenyl
- methylenedioxyphenyl
- methanol
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- -1 (3,4-methylenedioxyphenyl) -propyl Chemical group 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical class Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 2
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedeu pentru prepararea N-1(3,4-metilendioxifenil)-propil (2)-fenilpiperazine substituite, unor compusi cu formula generala I: (vezi form. in desc.) în care sa fie R1 este clor si R2 hidrogen, fie R1 este metil, o grupa metil si R2 este o grupa metoxi, caracterizat prin aceea ca un compus cu formula generala II. (vezi form. in desc.) în care R1 si R2 au semnificatia indicata anterior, se trateaza cu esterul metansulfonic al 1-(3,4-metilendioxifenil)-propan-2-olului în mediul de xilen, în prezenta carbonatului de potasiu la temperatura de reflux, sarea cu acid clorhidric a bazei libere obtinîndu-se în mod cunoscut prin tratarea în metanol cu acid clorhidric.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2442158A DE2442158C3 (de) | 1974-09-03 | 1974-09-03 | Neue substituierte N- [1(3,4-Methylendioxyphenyl) propyl (2)] -N'-subst Phenylpiperazine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO68380A RO68380A (ro) | 1983-04-29 |
| RO68380B true RO68380B (ro) | 1983-04-30 |
Family
ID=5924765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO83281A RO68380B (ro) | 1974-09-03 | 1975-08-28 | Procedeu pentru prepararea n-1-(3, 4-metilendioxifenil)-propil(2)-fenilpiperazine substituite |
Country Status (27)
| Country | Link |
|---|---|
| JP (1) | JPS52287A (ro) |
| AT (1) | AT344699B (ro) |
| BE (2) | BE833002A (ro) |
| BG (1) | BG26381A3 (ro) |
| CA (2) | CA1063027A (ro) |
| CH (1) | CH615174A5 (ro) |
| CS (1) | CS192521B2 (ro) |
| DD (1) | DD124118A5 (ro) |
| DE (1) | DE2442158C3 (ro) |
| DK (1) | DK137387C (ro) |
| ES (5) | ES440630A1 (ro) |
| FI (1) | FI60006C (ro) |
| FR (1) | FR2283682A1 (ro) |
| GB (3) | GB1521052A (ro) |
| HU (1) | HU176754B (ro) |
| IE (2) | IE41667B1 (ro) |
| IL (2) | IL48033A (ro) |
| LU (2) | LU73316A1 (ro) |
| NL (1) | NL7510319A (ro) |
| NO (1) | NO142911C (ro) |
| NZ (1) | NZ178566A (ro) |
| PH (1) | PH13631A (ro) |
| PL (1) | PL95233B1 (ro) |
| RO (1) | RO68380B (ro) |
| SE (1) | SE419084B (ro) |
| YU (1) | YU37164B (ro) |
| ZA (2) | ZA755601B (ro) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54109307U (ro) * | 1978-01-19 | 1979-08-01 | ||
| US4647606A (en) * | 1982-12-27 | 1987-03-03 | Owens-Corning Fiberglas Corporation | Blend of rapid set asphaltic emulsion with slow set asphalt emulsion |
| HU187229B (en) * | 1983-04-14 | 1985-11-28 | Koezponti Valto Hitelbank | Method for producing fodder increasing yield or additional fodder composition |
| AUPN359095A0 (en) * | 1995-06-19 | 1995-07-13 | Mount Shamrock Pty Ltd | Saw system |
-
1974
- 1974-09-03 DE DE2442158A patent/DE2442158C3/de not_active Expired
-
1975
- 1975-08-13 FI FI752288A patent/FI60006C/fi not_active IP Right Cessation
- 1975-08-25 AT AT653875A patent/AT344699B/de not_active IP Right Cessation
- 1975-08-28 RO RO83281A patent/RO68380B/ro unknown
- 1975-09-01 BG BG030900A patent/BG26381A3/xx unknown
- 1975-09-01 CS CS755930A patent/CS192521B2/cs unknown
- 1975-09-01 DD DD188118A patent/DD124118A5/xx unknown
- 1975-09-02 GB GB3218/78A patent/GB1521052A/en not_active Expired
- 1975-09-02 GB GB36147/75A patent/GB1521051A/en not_active Expired
- 1975-09-02 BE BE159686A patent/BE833002A/xx not_active IP Right Cessation
- 1975-09-02 PL PL1975183066A patent/PL95233B1/pl unknown
- 1975-09-02 IL IL48033A patent/IL48033A/xx unknown
- 1975-09-02 HU HU75BO1570A patent/HU176754B/hu unknown
- 1975-09-02 DK DK393775A patent/DK137387C/da active
- 1975-09-02 IL IL48036A patent/IL48036A/xx unknown
- 1975-09-02 NL NL7510319A patent/NL7510319A/xx not_active Application Discontinuation
- 1975-09-02 ES ES440630A patent/ES440630A1/es not_active Expired
- 1975-09-02 JP JP50106441A patent/JPS52287A/ja active Pending
- 1975-09-02 SE SE7509746A patent/SE419084B/xx unknown
- 1975-09-02 YU YU2219/75A patent/YU37164B/xx unknown
- 1975-09-02 GB GB36152/75A patent/GB1514546A/en not_active Expired
- 1975-09-02 NO NO753020A patent/NO142911C/no unknown
- 1975-09-02 BE BE159687A patent/BE833003A/xx not_active IP Right Cessation
- 1975-09-03 ZA ZA755601A patent/ZA755601B/xx unknown
- 1975-09-03 PH PH17540A patent/PH13631A/en unknown
- 1975-09-03 ZA ZA755602A patent/ZA755602B/xx unknown
- 1975-09-03 LU LU73316A patent/LU73316A1/xx unknown
- 1975-09-03 IE IE1929/75A patent/IE41667B1/en unknown
- 1975-09-03 CA CA234,708A patent/CA1063027A/en not_active Expired
- 1975-09-03 IE IE1930/75A patent/IE43338B1/en unknown
- 1975-09-03 NZ NZ178566A patent/NZ178566A/xx unknown
- 1975-09-03 LU LU73317A patent/LU73317A1/xx unknown
- 1975-09-03 FR FR7527056A patent/FR2283682A1/fr active Granted
- 1975-09-03 CA CA234,707A patent/CA1061343A/en not_active Expired
-
1976
- 1976-12-03 ES ES453932A patent/ES453932A1/es not_active Expired
- 1976-12-03 ES ES453934A patent/ES453934A1/es not_active Expired
- 1976-12-03 ES ES453935A patent/ES453935A1/es not_active Expired
- 1976-12-03 ES ES453933A patent/ES453933A1/es not_active Expired
-
1979
- 1979-05-07 CH CH425779A patent/CH615174A5/de not_active IP Right Cessation
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