RO80925B - Procedeu pentru prepararea unor derivati de nitrotiofen - Google Patents

Procedeu pentru prepararea unor derivati de nitrotiofen

Info

Publication number
RO80925B
RO80925B RO102884A RO10288480A RO80925B RO 80925 B RO80925 B RO 80925B RO 102884 A RO102884 A RO 102884A RO 10288480 A RO10288480 A RO 10288480A RO 80925 B RO80925 B RO 80925B
Authority
RO
Romania
Prior art keywords
carbon atoms
alpha
alkyl
group
preparation
Prior art date
Application number
RO102884A
Other languages
English (en)
Other versions
RO80925A (ro
Inventor
Hendrik Dolman
Johannes Kuipers
Original Assignee
Duphar International Research B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research B.V. filed Critical Duphar International Research B.V.
Publication of RO80925A publication Critical patent/RO80925A/ro
Publication of RO80925B publication Critical patent/RO80925B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/42—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/10—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with sulfur as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Inventia se refera la un procedeu pentru prepararea unor derivati de nitrotiofen cu formula generala I: (vezi form. in desc.) în care R este o grupare alchil cu 1....12 atomi de carbon, eventual substituit cu o grupare alcoxicarbonil cu 2....5 atomi de carbon sau cu o grupare tiocianat sau cu un radical fenol, piridil sau N-oxipiridil, eventual substituite cu nitro, halogen, alchil cu 1....4 atomi de carbon sau alcoxi cu 1...4 atomi de carbon, R1 este un atom de hidrogen, de halogen, alchil cu 1...4 atomi de carbon sau fenil, R2 este un atom de hidrogen, o grupare alchil cu 1...4 atomi de carbon, o grupareciano, o grupare alcanoil cu 1....5 atomi de carbon, o grupare alfa alfa-dialcoxialchil cu 3....10 atomi de carbon alcoxicarbonil cu 2...5 atomi de carbon alfa -hidroxialchil cu 1....4 atomi de carbon, alfa-haloalchil cu 1.....4 atomi de carbon, alfa -alcoxialchil cu 2....6 atomi de carbon, alcoxicarboximidol cu 2...5 atomi de carbon, dialchilaminosulfonil, n este 1 sau 2 caracterizat prin aceea ca un compus cu formula generala II:)vezi form. in desc.)....
RO102884A 1979-12-19 1980-12-18 Procedeu pentru prepararea unor derivati de nitrotiofen RO80925B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7909124 1979-12-19

Publications (2)

Publication Number Publication Date
RO80925A RO80925A (ro) 1983-04-29
RO80925B true RO80925B (ro) 1983-04-30

Family

ID=19834337

Family Applications (1)

Application Number Title Priority Date Filing Date
RO102884A RO80925B (ro) 1979-12-19 1980-12-18 Procedeu pentru prepararea unor derivati de nitrotiofen

Country Status (23)

Country Link
US (2) US4451660A (ro)
EP (1) EP0031173B1 (ro)
JP (1) JPS5697282A (ro)
AR (1) AR227657A1 (ro)
AT (1) ATE4643T1 (ro)
AU (1) AU536144B2 (ro)
BG (1) BG34756A3 (ro)
BR (1) BR8008235A (ro)
CA (1) CA1150264A (ro)
CS (1) CS221944B2 (ro)
DD (1) DD155384A5 (ro)
DE (1) DE3064846D1 (ro)
DK (1) DK157299C (ro)
EG (1) EG14491A (ro)
ES (1) ES8200676A1 (ro)
HU (1) HU188758B (ro)
IL (1) IL61729A (ro)
NZ (1) NZ195851A (ro)
PL (1) PL125938B1 (ro)
RO (1) RO80925B (ro)
SU (1) SU1050564A3 (ro)
YU (1) YU317180A (ro)
ZA (1) ZA807898B (ro)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE4643T1 (de) * 1979-12-19 1983-09-15 Duphar International Research B.V Nitrothiophene, verfahren zur herstellung der verbindungen sowie fungizide und/oder bakterizide zusammensetzungen auf der basis dieser verbindungen.
EP0234622B1 (en) * 1986-02-19 1990-06-27 Duphar International Research B.V New thio compounds having fungicidal activity
EP0273602A1 (en) * 1986-12-05 1988-07-06 Eli Lilly And Company 3-Cyano-4-arylthiophenes
DE3812177A1 (de) * 1988-04-13 1989-10-26 Bayer Ag 2-phenylsulfinyl-nitro-pyridine, verfahren zu ihrer herstellung und ihre verwendung
TW319681B (ro) * 1995-09-01 1997-11-11 Rohm & Haas
DE19540951A1 (de) * 1995-11-03 1997-05-07 Basf Ag Wasserabsorbierende, schaumförmige, vernetzte Polymerisate, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19607529A1 (de) 1996-02-28 1997-09-04 Basf Ag Absorberelement aus superabsorbierenden Schäumen mit anisotropem Quellverhalten
DE19809540A1 (de) 1998-03-05 1999-09-09 Basf Ag Wasserabsorbierende, schaumförmige, vernetzte Polymerisate, Verfahren zu ihrer Herstellung und ihre Verwendung
JP4284189B2 (ja) * 2002-02-04 2009-06-24 ビーエーエスエフ ソシエタス・ヨーロピア 残留モノマー含分を低下させ、かつ、吸水性架橋ポリマーフォームから形成された物品の湿潤強度を高めるための方法、及び該物品の使用
US8680139B2 (en) 2009-04-01 2014-03-25 Progenra Anti-neoplastic compounds, compositions and methods
GB201514021D0 (en) 2015-08-07 2015-09-23 Arner Elias Set Jeno Novel Pyridines and their use in the treatment of cancer
EP3580215A1 (en) 2017-02-07 2019-12-18 Oblique Therapeutics AB Heteroarylsulfonyl-substituted pyridines and their use in the treatment of cancer
RU2019128063A (ru) 2017-02-07 2021-03-09 Облик Терапьютикс Аб Углеводородсульфонилзамещенные пиридины и их применение при лечении рака
US11208384B2 (en) 2017-02-07 2021-12-28 Oblique Therapeutics Ab Sulfinylpyridines and their use in the treatment of cancer
BR112019016233A2 (pt) * 2017-02-07 2020-04-07 Oblique Therapeutics Ab piridinas substituídas com heterociclilsulfonila e uso das mesmas no tratamento de câncer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2389128A (en) * 1941-12-13 1945-11-20 Parke Davis & Co Sulphones and method of preparing same
US2562988A (en) * 1948-12-18 1951-08-07 Texas Co Nitro-and thiocyano-substituted thiophene compounds
US3682968A (en) * 1969-06-25 1972-08-08 Merck & Co Inc Anti-inflammatory salicylic acid derivatives
JPS526563B2 (ro) * 1972-04-24 1977-02-23
ATE4643T1 (de) * 1979-12-19 1983-09-15 Duphar International Research B.V Nitrothiophene, verfahren zur herstellung der verbindungen sowie fungizide und/oder bakterizide zusammensetzungen auf der basis dieser verbindungen.

Also Published As

Publication number Publication date
PL228509A1 (ro) 1982-02-01
AU536144B2 (en) 1984-04-19
ATE4643T1 (de) 1983-09-15
CS221944B2 (en) 1983-04-29
HU188758B (en) 1986-05-28
ZA807898B (en) 1982-07-28
IL61729A0 (en) 1981-01-30
US4649154A (en) 1987-03-10
EP0031173B1 (en) 1983-09-14
ES497831A0 (es) 1981-11-01
DK157299C (da) 1990-05-07
CA1150264A (en) 1983-07-19
BR8008235A (pt) 1981-07-07
DK534780A (da) 1981-06-20
SU1050564A3 (ru) 1983-10-23
DE3064846D1 (en) 1983-10-20
ES8200676A1 (es) 1981-11-01
AR227657A1 (es) 1982-11-30
US4451660A (en) 1984-05-29
DK157299B (da) 1989-12-04
RO80925A (ro) 1983-04-29
EP0031173A1 (en) 1981-07-01
JPS5697282A (en) 1981-08-05
NZ195851A (en) 1983-09-30
YU317180A (en) 1983-02-28
EG14491A (en) 1984-06-30
BG34756A3 (en) 1983-11-15
JPH0249281B2 (ro) 1990-10-29
DD155384A5 (de) 1982-06-09
IL61729A (en) 1986-08-31
AU6543080A (en) 1981-06-25
PL125938B1 (en) 1983-06-30

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