ES2062136T3 - Un procedimiento para producir un derivado de bencenosulfonamida opticamente activo. - Google Patents

Un procedimiento para producir un derivado de bencenosulfonamida opticamente activo.

Info

Publication number
ES2062136T3
ES2062136T3 ES90104584T ES90104584T ES2062136T3 ES 2062136 T3 ES2062136 T3 ES 2062136T3 ES 90104584 T ES90104584 T ES 90104584T ES 90104584 T ES90104584 T ES 90104584T ES 2062136 T3 ES2062136 T3 ES 2062136T3
Authority
ES
Spain
Prior art keywords
alkyl
derivative
optically active
benzenosulfonamide
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90104584T
Other languages
English (en)
Inventor
Minoru Postal Code C O C Okada
Koichi Yoshida
Kiyoshi Takanobu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2062136T3 publication Critical patent/ES2062136T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCESO PARA LA PRODUCCION DE DERIVADOS DE BENCENOSULFONAMIDA OPTICAMENTE ACTIVOS (I) QUE COMPRENDE LA DESCOMPOSICION DEL DERIVADO M-(2-SUSTITUIDO-ALQUILAMINOALQUIL)BENCENO-SULFONAMIDA (II): EN DONDE R1 Y R2 SE SELECCIONAN INDEPENDIENTEMENTE DE UN ATOMO DE HIDROGENO Y GRUPOS ALQUILICOS; R3 ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILICO, HIDROXILO O ALCOHOXILO; R4 ES UN GRUPO ALQUILICO; R5 ES UN GRUPO ALQUILICO, CARBOXI-ALQUILICO O ALCOXICARBONIL-ALQUILICO; Y R6 ES UN GRUPO FENILICO SUSTITUIDO O SIN SUSTITUIR. LOS COMPUESTOS DE LA FORMULA (II) SE OBTIENEN MEDIANTE LA REACCION DE UNA CETONA DE LA FORMULA (III)
ES90104584T 1986-07-21 1987-07-21 Un procedimiento para producir un derivado de bencenosulfonamida opticamente activo. Expired - Lifetime ES2062136T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61172285A JPH066565B2 (ja) 1986-07-21 1986-07-21 光学活性なベンゼンスルホンアミド誘導体の製造法

Publications (1)

Publication Number Publication Date
ES2062136T3 true ES2062136T3 (es) 1994-12-16

Family

ID=15939091

Family Applications (2)

Application Number Title Priority Date Filing Date
ES90104584T Expired - Lifetime ES2062136T3 (es) 1986-07-21 1987-07-21 Un procedimiento para producir un derivado de bencenosulfonamida opticamente activo.
ES198787306453T Expired - Lifetime ES2029838T3 (es) 1986-07-21 1987-07-21 Un procedimiento para producir un derivado de bencenosulfonamida opticamente activo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES198787306453T Expired - Lifetime ES2029838T3 (es) 1986-07-21 1987-07-21 Un procedimiento para producir un derivado de bencenosulfonamida opticamente activo.

Country Status (8)

Country Link
EP (2) EP0380144B1 (es)
JP (1) JPH066565B2 (es)
KR (1) KR960003810B1 (es)
AT (2) ATE62667T1 (es)
CA (1) CA1340332C (es)
DE (2) DE3788878T2 (es)
ES (2) ES2062136T3 (es)
IE (1) IE63344B1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4971990A (en) * 1988-02-19 1990-11-20 Hokuriku Pharmaceutical Co., Ltd. Phenoxyethylamine derivatives, for preparing the same and composition for exhibiting excellent α1 -blocking activity containing the same
JPH0345780A (ja) * 1989-07-12 1991-02-27 Minoru Ban 絹繊維製品の化学的加工法
US5288759A (en) * 1992-08-27 1994-02-22 Alcon Laboratories, Inc. Use of certain sulfamoyl-substituted phenethylamine derivatives to reverse drug-induced mydriasis
AU3883099A (en) 1998-05-06 1999-11-23 Duke University Method of treating bladder and lower urinary tract syndromes
US6835853B2 (en) * 2001-10-31 2004-12-28 Synthon Bv Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith
ES2200699B1 (es) * 2002-07-12 2005-10-01 Ragactives, S.L Procedimiento para la separacion de r(-) y s(+)-5-(2-((2-(etoxifenoxi)etil)amino)propil-2-metoxibenceno-sulfonamida.
HU225505B1 (en) * 2002-09-09 2007-01-29 Richter Gedeon Vegyeszet Process for the preparation of r-(-)-tamsulosin hydrochloride and novel intermediates
US20060173214A1 (en) * 2002-12-26 2006-08-03 Dubey Sushil K Process for the preparation of enantiomerically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide
WO2005056521A1 (en) * 2003-12-09 2005-06-23 Cj Corporation Method of preparing optically pure phenethylamine derivatives
SI21702A (en) * 2004-01-29 2005-08-31 Lek Farmacevtska Druzba Dd Preparation of amorphous form of tamsulosin
CZ2004197A3 (cs) * 2004-02-05 2005-08-17 Zentiva, A. S. Způsob výroby (R)-(-)-5-(2-aminopropyl)-2-methoxybenzensulfonamidu
WO2005080323A1 (en) * 2004-02-23 2005-09-01 Cadila Healthcare Limited Process for manufacturing optically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzene sulfonamide
WO2006004093A1 (ja) * 2004-07-07 2006-01-12 Hamari Chemicals, Ltd. 光学活性フェニルプロピルアミン誘導体の製法
CN100545148C (zh) 2004-08-16 2009-09-30 神隆新加坡私人有限公司 一种抗良性前列腺肥大药物坦索罗辛之合成方法
US7238839B2 (en) 2004-10-07 2007-07-03 Divi's Laboratories Limited Process for the resolution of racemic (R,S) -5-(2-(2-(2- ethoxyphenoxy) ethylamino)Propyl)-2-methoxybenzene sulfonamide (tamsulosin), its novel R and S isomers and their salts and processes for their preparation
KR101144776B1 (ko) * 2004-12-02 2012-05-11 연성정밀화학(주) 광학 활성 벤젠설폰아마이드 유도체의 제조방법
PT103216B (pt) 2004-12-06 2010-05-19 Hovione Farmaciencia S A Preparação de tamsulosin
US8273918B2 (en) 2005-09-12 2012-09-25 Avrobindo Pharma Ltd. Process for preparing tamsulosin hydrochloride
EP2026766A1 (en) 2006-05-17 2009-02-25 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
CN101190890B (zh) 2006-11-30 2011-04-27 江苏豪森药业股份有限公司 5-[(2r)-[2-[2-[2-(2,2,2-三氟乙氧基)苯氧基]乙基]氨基]丙基]-2-甲氧基苯磺酰胺
US8222452B2 (en) 2007-07-03 2012-07-17 Hamari Chemicals, Ltd. Method for producing optically active amines
WO2009086705A1 (zh) 2008-01-10 2009-07-16 Shanghai Institute Of Pharmaceutical Industry 利凡斯的明的制备方法、其中间体以及中间体的制备方法
CN101284807B (zh) * 2008-06-11 2010-12-08 药源药物化学（上海）有限公司 盐酸坦索罗辛的制备方法
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
EP2255793A1 (en) 2009-05-28 2010-12-01 Krka Tovarna Zdravil, D.D., Novo Mesto Pharmaceutical composition comprising tamsulosin
DE102012022670A1 (de) 2012-11-21 2014-05-22 Friedrich-Alexander-Universität Erlangen-Nürnberg Verfahren zur Herstellung enantiomerenangereicherter und enantiomerenreiner Nitroalkane und Amine
CN111320559A (zh) * 2018-12-14 2020-06-23 苏州盛迪亚生物医药有限公司 一种盐酸坦索罗辛的制备方法
DE202023102187U1 (de) 2023-04-25 2023-05-02 Nusrath Anjum Auf Tamsulosin basierende Derivatformulierung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000197A (en) * 1973-07-23 1976-12-28 The University Of Iowa Research Foundation Asymmetric synthesis of phenylisopropylamines
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
US4658060A (en) * 1982-04-26 1987-04-14 Schering Corporation Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide

Also Published As

Publication number Publication date
KR960003810B1 (ko) 1996-03-22
EP0257787A1 (en) 1988-03-02
ATE62667T1 (de) 1991-05-15
ATE100444T1 (de) 1994-02-15
IE871960L (en) 1988-01-21
EP0380144B1 (en) 1994-01-19
DE3769399D1 (de) 1991-05-23
EP0257787B1 (en) 1991-04-17
CA1340332C (en) 1999-01-26
DE3788878D1 (de) 1994-03-03
EP0380144A1 (en) 1990-08-01
DE3788878T2 (de) 1994-05-05
JPH066565B2 (ja) 1994-01-26
JPS6327471A (ja) 1988-02-05
ES2029838T3 (es) 1992-10-01
IE63344B1 (en) 1995-04-19
KR880001583A (ko) 1988-04-25

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