ATE62667T1 - Verfahren zur herstellung von optisch aktiven benzensulfonamid-derivaten. - Google Patents

Verfahren zur herstellung von optisch aktiven benzensulfonamid-derivaten.

Info

Publication number
ATE62667T1
ATE62667T1 AT87306453T AT87306453T ATE62667T1 AT E62667 T1 ATE62667 T1 AT E62667T1 AT 87306453 T AT87306453 T AT 87306453T AT 87306453 T AT87306453 T AT 87306453T AT E62667 T1 ATE62667 T1 AT E62667T1
Authority
AT
Austria
Prior art keywords
alkyl
optically active
preparation
benzene sulphonamide
sulphonamide derivatives
Prior art date
Application number
AT87306453T
Other languages
English (en)
Inventor
Minoru Okada
Koichi Yoshida
Kiyoshi Takanobu
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Application granted granted Critical
Publication of ATE62667T1 publication Critical patent/ATE62667T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT87306453T 1986-07-21 1987-07-21 Verfahren zur herstellung von optisch aktiven benzensulfonamid-derivaten. ATE62667T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61172285A JPH066565B2 (ja) 1986-07-21 1986-07-21 光学活性なベンゼンスルホンアミド誘導体の製造法
EP87306453A EP0257787B1 (de) 1986-07-21 1987-07-21 Verfahren zur Herstellung von optisch aktiven Benzensulfonamid-Derivaten

Publications (1)

Publication Number Publication Date
ATE62667T1 true ATE62667T1 (de) 1991-05-15

Family

ID=15939091

Family Applications (2)

Application Number Title Priority Date Filing Date
AT87306453T ATE62667T1 (de) 1986-07-21 1987-07-21 Verfahren zur herstellung von optisch aktiven benzensulfonamid-derivaten.
AT90104584T ATE100444T1 (de) 1986-07-21 1990-03-10 Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT90104584T ATE100444T1 (de) 1986-07-21 1990-03-10 Verfahren zur herstellung von optisch aktiven benzolsulfonamidderivaten.

Country Status (8)

Country Link
EP (2) EP0257787B1 (de)
JP (1) JPH066565B2 (de)
KR (1) KR960003810B1 (de)
AT (2) ATE62667T1 (de)
CA (1) CA1340332C (de)
DE (2) DE3788878T2 (de)
ES (2) ES2062136T3 (de)
IE (1) IE63344B1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4971990A (en) * 1988-02-19 1990-11-20 Hokuriku Pharmaceutical Co., Ltd. Phenoxyethylamine derivatives, for preparing the same and composition for exhibiting excellent α1 -blocking activity containing the same
JPH0345780A (ja) * 1989-07-12 1991-02-27 Minoru Ban 絹繊維製品の化学的加工法
US5288759A (en) * 1992-08-27 1994-02-22 Alcon Laboratories, Inc. Use of certain sulfamoyl-substituted phenethylamine derivatives to reverse drug-induced mydriasis
MXPA00010805A (es) 1998-05-06 2002-05-08 Univ Duke Metodo para el tratamiento de sindromes de la vejiga y del tracto urinario inferior.
US6835853B2 (en) 2001-10-31 2004-12-28 Synthon Bv Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith
ES2200699B1 (es) * 2002-07-12 2005-10-01 Ragactives, S.L Procedimiento para la separacion de r(-) y s(+)-5-(2-((2-(etoxifenoxi)etil)amino)propil-2-metoxibenceno-sulfonamida.
HU225505B1 (en) * 2002-09-09 2007-01-29 Richter Gedeon Vegyeszet Process for the preparation of r-(-)-tamsulosin hydrochloride and novel intermediates
US20060173214A1 (en) * 2002-12-26 2006-08-03 Dubey Sushil K Process for the preparation of enantiomerically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide
KR100596373B1 (ko) 2003-12-09 2006-07-04 씨제이 주식회사 광학적으로 순수한 펜에틸 아민 유도체의 제조방법
SI21702A (en) * 2004-01-29 2005-08-31 Lek Farmacevtska Druzba Dd Preparation of amorphous form of tamsulosin
CZ2004197A3 (cs) * 2004-02-05 2005-08-17 Zentiva, A. S. Způsob výroby (R)-(-)-5-(2-aminopropyl)-2-methoxybenzensulfonamidu
WO2005080323A1 (en) * 2004-02-23 2005-09-01 Cadila Healthcare Limited Process for manufacturing optically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzene sulfonamide
WO2006004093A1 (ja) * 2004-07-07 2006-01-12 Hamari Chemicals, Ltd. 光学活性フェニルプロピルアミン誘導体の製法
CN100545148C (zh) * 2004-08-16 2009-09-30 神隆新加坡私人有限公司 一种抗良性前列腺肥大药物坦索罗辛之合成方法
US7238839B2 (en) 2004-10-07 2007-07-03 Divi's Laboratories Limited Process for the resolution of racemic (R,S) -5-(2-(2-(2- ethoxyphenoxy) ethylamino)Propyl)-2-methoxybenzene sulfonamide (tamsulosin), its novel R and S isomers and their salts and processes for their preparation
KR101144776B1 (ko) * 2004-12-02 2012-05-11 연성정밀화학(주) 광학 활성 벤젠설폰아마이드 유도체의 제조방법
PT103216B (pt) 2004-12-06 2010-05-19 Hovione Farmaciencia S A Preparação de tamsulosin
US8273918B2 (en) 2005-09-12 2012-09-25 Avrobindo Pharma Ltd. Process for preparing tamsulosin hydrochloride
WO2007131804A1 (en) 2006-05-17 2007-11-22 Synthon B.V. Tablet composition with a prolonged release of tamsulosin
CN101190890B (zh) 2006-11-30 2011-04-27 江苏豪森药业股份有限公司 5-[(2r)-[2-[2-[2-(2,2,2-三氟乙氧基)苯氧基]乙基]氨基]丙基]-2-甲氧基苯磺酰胺
US8222452B2 (en) * 2007-07-03 2012-07-17 Hamari Chemicals, Ltd. Method for producing optically active amines
CN101910110B (zh) 2008-01-10 2013-05-22 上海医药工业研究院 利凡斯的明的制备方法、其中间体以及中间体的制备方法
CN101284807B (zh) * 2008-06-11 2010-12-08 药源药物化学（上海）有限公司 盐酸坦索罗辛的制备方法
US8465770B2 (en) 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
EP2255793A1 (de) 2009-05-28 2010-12-01 Krka Tovarna Zdravil, D.D., Novo Mesto Pharmazeutische Zusammensetzung mit Tamsulosin
DE102012022670A1 (de) 2012-11-21 2014-05-22 Friedrich-Alexander-Universität Erlangen-Nürnberg Verfahren zur Herstellung enantiomerenangereicherter und enantiomerenreiner Nitroalkane und Amine
CN111320559A (zh) * 2018-12-14 2020-06-23 苏州盛迪亚生物医药有限公司 一种盐酸坦索罗辛的制备方法
DE202023102187U1 (de) 2023-04-25 2023-05-02 Nusrath Anjum Auf Tamsulosin basierende Derivatformulierung
CN117024314B (zh) * 2023-08-09 2025-07-18 常州瑞明药业有限公司 一种(r)-5-(2-氨基丙基)-2-甲氧基苯磺酰胺的合成方法
CN119019296A (zh) * 2024-10-24 2024-11-26 江苏恒瑞医药股份有限公司 一种固载催化剂制备坦索罗辛或其可药用盐的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000197A (en) * 1973-07-23 1976-12-28 The University Of Iowa Research Foundation Asymmetric synthesis of phenylisopropylamines
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
US4658060A (en) * 1982-04-26 1987-04-14 Schering Corporation Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide

Also Published As

Publication number Publication date
KR880001583A (ko) 1988-04-25
JPH066565B2 (ja) 1994-01-26
EP0380144A1 (de) 1990-08-01
KR960003810B1 (ko) 1996-03-22
EP0257787B1 (de) 1991-04-17
DE3788878D1 (de) 1994-03-03
ATE100444T1 (de) 1994-02-15
DE3788878T2 (de) 1994-05-05
IE871960L (en) 1988-01-21
CA1340332C (en) 1999-01-26
EP0257787A1 (de) 1988-03-02
EP0380144B1 (de) 1994-01-19
JPS6327471A (ja) 1988-02-05
ES2062136T3 (es) 1994-12-16
ES2029838T3 (es) 1992-10-01
IE63344B1 (en) 1995-04-19
DE3769399D1 (de) 1991-05-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
EELA Cancelled due to lapse of time