IE43338L - Pharmaceutical composition - Google Patents

Pharmaceutical composition

Info

Publication number
IE43338L
IE43338L IE751930A IE193075A IE43338L IE 43338 L IE43338 L IE 43338L IE 751930 A IE751930 A IE 751930A IE 193075 A IE193075 A IE 193075A IE 43338 L IE43338 L IE 43338L
Authority
IE
Ireland
Prior art keywords
formula
lowering
appropriately substituted
action
denotes
Prior art date
Application number
IE751930A
Other versions
IE43338B1 (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to IE1840/80A priority Critical patent/IE43339B1/en
Publication of IE43338L publication Critical patent/IE43338L/en
Publication of IE43338B1 publication Critical patent/IE43338B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

Novel substituted N-[1-(3,4-methylenedioxyphenyl)-propyl-(2)]-N'-phenylpiperazines of the formula I shown, wherein either R1 and R2 denote chlorine or R1 denotes methyl and R2 denotes methoxy, are prepared by treating an appropriately substituted halogenopropane, especially an appropriately substituted chloropropane, with catalytically activated hydrogen. Advantageously, the process is carried out in the presence of an acid-binding agent and at an elevated temperature. The compounds of the formula I may be obtained in the form of the racemates or of the optically active antipodes. The products of the process show a good central-depressant action as well as an excellent blood lipid level-lowering and cholesterol-lowering action. <IMAGE> [GB1514546A]
IE1930/75A 1974-09-03 1975-09-03 Pharmaceutical compositions IE43338B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1840/80A IE43339B1 (en) 1974-09-03 1975-09-03 Pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2442158A DE2442158C3 (en) 1974-09-03 1974-09-03 New substituted N- [1 (3,4-methylenedioxyphenyl) propyl (2)] -N'-subst phenylpiperazines

Publications (2)

Publication Number Publication Date
IE43338L true IE43338L (en) 1976-03-03
IE43338B1 IE43338B1 (en) 1981-02-11

Family

ID=5924765

Family Applications (2)

Application Number Title Priority Date Filing Date
IE1929/75A IE41667B1 (en) 1974-09-03 1975-09-03 Substituted phenylpiperazine compounds and pharmaceutical uses thereof
IE1930/75A IE43338B1 (en) 1974-09-03 1975-09-03 Pharmaceutical compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IE1929/75A IE41667B1 (en) 1974-09-03 1975-09-03 Substituted phenylpiperazine compounds and pharmaceutical uses thereof

Country Status (27)

Country Link
JP (1) JPS52287A (en)
AT (1) AT344699B (en)
BE (2) BE833003A (en)
BG (1) BG26381A3 (en)
CA (2) CA1061343A (en)
CH (1) CH615174A5 (en)
CS (1) CS192521B2 (en)
DD (1) DD124118A5 (en)
DE (1) DE2442158C3 (en)
DK (1) DK137387C (en)
ES (5) ES440630A1 (en)
FI (1) FI60006C (en)
FR (1) FR2283682A1 (en)
GB (3) GB1514546A (en)
HU (1) HU176754B (en)
IE (2) IE41667B1 (en)
IL (2) IL48033A (en)
LU (2) LU73316A1 (en)
NL (1) NL7510319A (en)
NO (1) NO142911C (en)
NZ (1) NZ178566A (en)
PH (1) PH13631A (en)
PL (1) PL95233B1 (en)
RO (1) RO68380B (en)
SE (1) SE419084B (en)
YU (1) YU37164B (en)
ZA (2) ZA755602B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54109307U (en) * 1978-01-19 1979-08-01
US4647606A (en) * 1982-12-27 1987-03-03 Owens-Corning Fiberglas Corporation Blend of rapid set asphaltic emulsion with slow set asphalt emulsion
HU187229B (en) * 1983-04-14 1985-11-28 Koezponti Valto Hitelbank Method for producing fodder increasing yield or additional fodder composition
AUPN359095A0 (en) * 1995-06-19 1995-07-13 Mount Shamrock Pty Ltd Saw system

Also Published As

Publication number Publication date
NO142911B (en) 1980-08-04
DE2442158B2 (en) 1979-01-04
NZ178566A (en) 1978-03-06
CA1061343A (en) 1979-08-28
SE7509746L (en) 1976-03-04
JPS52287A (en) 1977-01-05
IL48036A0 (en) 1975-11-25
DK137387B (en) 1978-02-27
ZA755602B (en) 1977-05-25
ES453934A1 (en) 1977-11-16
CH615174A5 (en) 1980-01-15
IE41667L (en) 1976-03-03
NO753020L (en) 1976-03-04
IE43338B1 (en) 1981-02-11
DK137387C (en) 1978-09-04
GB1514546A (en) 1978-06-14
GB1521052A (en) 1978-08-09
PH13631A (en) 1980-08-14
SE419084B (en) 1981-07-13
IL48036A (en) 1978-07-31
ATA653875A (en) 1977-12-15
BG26381A3 (en) 1979-03-15
YU37164B (en) 1984-08-31
ES453935A1 (en) 1977-11-16
AU8445575A (en) 1977-03-10
FR2283682A1 (en) 1976-04-02
RO68380B (en) 1983-04-30
DD124118A5 (en) 1977-02-02
GB1521051A (en) 1978-08-09
BE833003A (en) 1976-03-02
DE2442158A1 (en) 1976-03-18
NO142911C (en) 1980-11-12
FI60006C (en) 1981-11-10
DE2442158C3 (en) 1979-08-30
AT344699B (en) 1978-08-10
HU176754B (en) 1981-05-28
IL48033A0 (en) 1975-11-25
LU73316A1 (en) 1977-01-28
CA1063027A (en) 1979-09-25
RO68380A (en) 1983-04-29
IL48033A (en) 1978-07-31
FR2283682B1 (en) 1978-11-10
ES453933A1 (en) 1977-11-16
ZA755601B (en) 1977-05-25
FI752288A (en) 1976-03-04
NL7510319A (en) 1976-03-05
LU73317A1 (en) 1977-01-28
BE833002A (en) 1976-03-02
AU8445675A (en) 1977-03-10
PL95233B1 (en) 1977-09-30
ES440630A1 (en) 1977-06-16
ES453932A1 (en) 1977-11-01
YU221975A (en) 1983-04-27
FI60006B (en) 1981-07-31
DK393775A (en) 1976-03-04
IE41667B1 (en) 1980-02-27
CS192521B2 (en) 1979-08-31

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