JPS5517344A - 2-substituted aminotetralin derivative - Google Patents
2-substituted aminotetralin derivativeInfo
- Publication number
- JPS5517344A JPS5517344A JP9010278A JP9010278A JPS5517344A JP S5517344 A JPS5517344 A JP S5517344A JP 9010278 A JP9010278 A JP 9010278A JP 9010278 A JP9010278 A JP 9010278A JP S5517344 A JPS5517344 A JP S5517344A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- lower alkoxy
- substituted
- aminotetralin derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:2-Substituted aminotetralins of formula I (When R1 is H, either R2 or R3 is lower alkoxy and the other is H or both incorporate to form lower alkylenedioxy; when R1 is lower alkoxy, R2 and R3 are H; R4 is lower alkylene of 2 or more carbon atoms) or their salts.
EXAMPLE: N-Ethyl-6-methoxy-1,2,3,4-tetrahydro-2-naphthylamine hydrochloride.
USE: Synthetic intermediates of drugs, e.g., an intermediate of spasmolysant for smooth muscle organs as gastrointestinal tracts.
PREPARATION: In the presence of a lower alkyl or cycloalkylamine of formula III, a compound of formula II is catalytically hydrogenated using a platinum oxide catalyst and an alcohol solvent under normal or elevated pressure to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9010278A JPS6058223B2 (en) | 1978-07-24 | 1978-07-24 | 2-substituted aminotetralin derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9010278A JPS6058223B2 (en) | 1978-07-24 | 1978-07-24 | 2-substituted aminotetralin derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5517344A true JPS5517344A (en) | 1980-02-06 |
JPS6058223B2 JPS6058223B2 (en) | 1985-12-19 |
Family
ID=13989145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9010278A Expired JPS6058223B2 (en) | 1978-07-24 | 1978-07-24 | 2-substituted aminotetralin derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6058223B2 (en) |
-
1978
- 1978-07-24 JP JP9010278A patent/JPS6058223B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6058223B2 (en) | 1985-12-19 |
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