JPS6426559A - Novel phthalide derivative - Google Patents
Novel phthalide derivativeInfo
- Publication number
- JPS6426559A JPS6426559A JP18222787A JP18222787A JPS6426559A JP S6426559 A JPS6426559 A JP S6426559A JP 18222787 A JP18222787 A JP 18222787A JP 18222787 A JP18222787 A JP 18222787A JP S6426559 A JPS6426559 A JP S6426559A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- give
- alkyl
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by shown by formula I [R1 and R2 are H, OH or methoxy; R3 and R4 are H or methoxy; R<5> is alkyl; R<6> is H, alkyl or group shown by formula II (R<7> is methyl or phenyl)]. EXAMPLE:3-Butyl-2-ethylphthalimidine. USE:A drug having lowering action on blood viscosity. PREPARATION:A compound shown by formula III is treated with an alkyl halide in the presence of a base to give a compound shown by formula IV, which is hydrolyzed to give a compound shown by formula V, which is converted into a methyl ester and the methyl ester is brominated at the benzyl position to give a compound shown by formula VI, which is reacted with a compound shown by the formula X-NH2 (X is H or alkyl) to give a compound shown by formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62182227A JP2621194B2 (en) | 1987-07-23 | 1987-07-23 | New phthalide derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62182227A JP2621194B2 (en) | 1987-07-23 | 1987-07-23 | New phthalide derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6426559A true JPS6426559A (en) | 1989-01-27 |
JP2621194B2 JP2621194B2 (en) | 1997-06-18 |
Family
ID=16114566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62182227A Expired - Lifetime JP2621194B2 (en) | 1987-07-23 | 1987-07-23 | New phthalide derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2621194B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103655555A (en) * | 2012-09-14 | 2014-03-26 | 中山大学 | Application of 3-n-isoindoline-1-ketone in preparation of medicament for preventing and treating cerebral infarction |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50154293A (en) * | 1974-05-15 | 1975-12-12 | ||
JPS62190162A (en) * | 1986-02-18 | 1987-08-20 | Asahi Glass Co Ltd | Optically active lactam compound and liquid crystal composition using said compound |
-
1987
- 1987-07-23 JP JP62182227A patent/JP2621194B2/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50154293A (en) * | 1974-05-15 | 1975-12-12 | ||
JPS62190162A (en) * | 1986-02-18 | 1987-08-20 | Asahi Glass Co Ltd | Optically active lactam compound and liquid crystal composition using said compound |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103655555A (en) * | 2012-09-14 | 2014-03-26 | 中山大学 | Application of 3-n-isoindoline-1-ketone in preparation of medicament for preventing and treating cerebral infarction |
Also Published As
Publication number | Publication date |
---|---|
JP2621194B2 (en) | 1997-06-18 |
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