PT90261B - Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno - Google Patents

Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno Download PDF

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Publication number
PT90261B
PT90261B PT90261A PT9026189A PT90261B PT 90261 B PT90261 B PT 90261B PT 90261 A PT90261 A PT 90261A PT 9026189 A PT9026189 A PT 9026189A PT 90261 B PT90261 B PT 90261B
Authority
PT
Portugal
Prior art keywords
general formula
group
symbol
alkaline
derivative
Prior art date
Application number
PT90261A
Other languages
English (en)
Portuguese (pt)
Other versions
PT90261A (pt
Inventor
Jean-Daniel Brion
Guillaume Le Baut
Patrick Ducrey
Sylvie Piessard-Robert
Claude Cudennec
Genevieve Seurre
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of PT90261A publication Critical patent/PT90261A/pt
Publication of PT90261B publication Critical patent/PT90261B/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT90261A 1988-04-13 1989-04-12 Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno PT90261B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8804870A FR2630110B1 (fr) 1988-04-13 1988-04-13 Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
PT90261A PT90261A (pt) 1989-11-10
PT90261B true PT90261B (pt) 1994-07-29

Family

ID=9365267

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90261A PT90261B (pt) 1988-04-13 1989-04-12 Processo para a preparacao de novos derivados com a estrutura do 3-(1-fenil-2-propenil)-{2h}-cromeno

Country Status (16)

Country Link
US (1) US4975455A (da)
EP (1) EP0338895B1 (da)
JP (1) JPH01305078A (da)
AT (1) ATE80881T1 (da)
AU (1) AU610379B2 (da)
CA (1) CA1326674C (da)
DE (1) DE68902946T2 (da)
DK (1) DK179289A (da)
ES (1) ES2035598T3 (da)
FR (1) FR2630110B1 (da)
GR (1) GR3006480T3 (da)
IE (1) IE64357B1 (da)
NZ (1) NZ228716A (da)
OA (1) OA09114A (da)
PT (1) PT90261B (da)
ZA (1) ZA892716B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5250547A (en) * 1991-08-29 1993-10-05 Syntex (U.S.A.) Inc. Benzopyran derivatives
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
JPH0852659A (ja) * 1994-08-08 1996-02-27 Tousetsu Denki Kk バイス
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651034A5 (de) * 1982-05-12 1985-08-30 Hoffmann La Roche Chroman-, thiochroman- oder 1,2,3,4-tetrahydrochinolinderivate und ihre verwendung als arzneimittel-wirkstoffe.
US4808597A (en) * 1983-07-05 1989-02-28 Pfizer Inc. Method for inhibiting the degradation of cartilage
JPS60178815A (ja) * 1984-02-24 1985-09-12 Rikagaku Kenkyusho 制癌剤
US4826984A (en) * 1984-04-09 1989-05-02 The Board Of Regents For The Oklahoma Agricultural And Mechanical College Acting For And On Behalf Of Oklahoma State University Heteroarotinoid compounds as anticancer agents
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant

Also Published As

Publication number Publication date
IE64357B1 (en) 1995-07-26
FR2630110A1 (fr) 1989-10-20
DE68902946D1 (de) 1992-10-29
ATE80881T1 (de) 1992-10-15
ES2035598T3 (es) 1993-04-16
JPH01305078A (ja) 1989-12-08
GR3006480T3 (da) 1993-06-21
EP0338895B1 (fr) 1992-09-23
DK179289A (da) 1989-10-14
EP0338895A1 (fr) 1989-10-25
CA1326674C (fr) 1994-02-01
AU610379B2 (en) 1991-05-16
IE891161L (en) 1989-10-13
NZ228716A (en) 1990-11-27
JPH0585550B2 (da) 1993-12-07
US4975455A (en) 1990-12-04
PT90261A (pt) 1989-11-10
AU3265989A (en) 1989-12-21
DE68902946T2 (de) 1993-04-29
FR2630110B1 (fr) 1990-07-27
ZA892716B (en) 1989-12-27
DK179289D0 (da) 1989-04-13
OA09114A (fr) 1991-10-31

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Effective date: 19940105

MM3A Annulment or lapse

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Effective date: 19970731