ATE80881T1 - Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents

Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Info

Publication number
ATE80881T1
ATE80881T1 AT89401016T AT89401016T ATE80881T1 AT E80881 T1 ATE80881 T1 AT E80881T1 AT 89401016 T AT89401016 T AT 89401016T AT 89401016 T AT89401016 T AT 89401016T AT E80881 T1 ATE80881 T1 AT E80881T1
Authority
AT
Austria
Prior art keywords
group
aminocarbonyl
lower alkyl
alkyloxy
heteroarotinoid
Prior art date
Application number
AT89401016T
Other languages
English (en)
Inventor
Jean Daniel Brion
Baut Guillaume Le
Patrick Ducrey
Sylvie Piessard-Robert
Claude Cudennec
Genevieve Seurre
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE80881T1 publication Critical patent/ATE80881T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
AT89401016T 1988-04-13 1989-04-13 Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. ATE80881T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8804870A FR2630110B1 (fr) 1988-04-13 1988-04-13 Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP89401016A EP0338895B1 (de) 1988-04-13 1989-04-13 Heteroarotinoid-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen

Publications (1)

Publication Number Publication Date
ATE80881T1 true ATE80881T1 (de) 1992-10-15

Family

ID=9365267

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89401016T ATE80881T1 (de) 1988-04-13 1989-04-13 Heteroarotinoid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.

Country Status (16)

Country Link
US (1) US4975455A (de)
EP (1) EP0338895B1 (de)
JP (1) JPH01305078A (de)
AT (1) ATE80881T1 (de)
AU (1) AU610379B2 (de)
CA (1) CA1326674C (de)
DE (1) DE68902946T2 (de)
DK (1) DK179289A (de)
ES (1) ES2035598T3 (de)
FR (1) FR2630110B1 (de)
GR (1) GR3006480T3 (de)
IE (1) IE64357B1 (de)
NZ (1) NZ228716A (de)
OA (1) OA09114A (de)
PT (1) PT90261B (de)
ZA (1) ZA892716B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5250547A (en) * 1991-08-29 1993-10-05 Syntex (U.S.A.) Inc. Benzopyran derivatives
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
JPH0852659A (ja) * 1994-08-08 1996-02-27 Tousetsu Denki Kk バイス
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651034A5 (de) * 1982-05-12 1985-08-30 Hoffmann La Roche Chroman-, thiochroman- oder 1,2,3,4-tetrahydrochinolinderivate und ihre verwendung als arzneimittel-wirkstoffe.
US4808597A (en) * 1983-07-05 1989-02-28 Pfizer Inc. Method for inhibiting the degradation of cartilage
JPS60178815A (ja) * 1984-02-24 1985-09-12 Rikagaku Kenkyusho 制癌剤
US4826984A (en) * 1984-04-09 1989-05-02 The Board Of Regents For The Oklahoma Agricultural And Mechanical College Acting For And On Behalf Of Oklahoma State University Heteroarotinoid compounds as anticancer agents
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant

Also Published As

Publication number Publication date
JPH0585550B2 (de) 1993-12-07
EP0338895A1 (de) 1989-10-25
PT90261B (pt) 1994-07-29
CA1326674C (fr) 1994-02-01
ES2035598T3 (es) 1993-04-16
US4975455A (en) 1990-12-04
DK179289A (da) 1989-10-14
NZ228716A (en) 1990-11-27
AU610379B2 (en) 1991-05-16
EP0338895B1 (de) 1992-09-23
OA09114A (fr) 1991-10-31
GR3006480T3 (de) 1993-06-21
FR2630110A1 (fr) 1989-10-20
IE64357B1 (en) 1995-07-26
AU3265989A (en) 1989-12-21
JPH01305078A (ja) 1989-12-08
DK179289D0 (da) 1989-04-13
DE68902946T2 (de) 1993-04-29
DE68902946D1 (de) 1992-10-29
IE891161L (en) 1989-10-13
ZA892716B (en) 1989-12-27
PT90261A (pt) 1989-11-10
FR2630110B1 (fr) 1990-07-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee