ZA892716B - Heteroarotinoid derivatives,processes for preparing them and pharmaceutical compositions containing them - Google Patents

Heteroarotinoid derivatives,processes for preparing them and pharmaceutical compositions containing them

Info

Publication number
ZA892716B
ZA892716B ZA892716A ZA892716A ZA892716B ZA 892716 B ZA892716 B ZA 892716B ZA 892716 A ZA892716 A ZA 892716A ZA 892716 A ZA892716 A ZA 892716A ZA 892716 B ZA892716 B ZA 892716B
Authority
ZA
South Africa
Prior art keywords
group
aminocarbonyl
lower alkyl
alkyloxy
heteroarotinoid
Prior art date
Application number
ZA892716A
Other languages
English (en)
Inventor
Jean-Daniel Brion
Brion Jean-Daniel
Guillaume Le Baut
Le Baut Guillaume
Patrick Ducrey
Ducrey Patrick
Sylvie Piessard-Robert
Piessard-Robert Sylvie
Claude Cudennec
Cudennec Claude
Genevieve Seurre
Seurre Genevieve
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA892716B publication Critical patent/ZA892716B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA892716A 1988-04-13 1989-04-13 Heteroarotinoid derivatives,processes for preparing them and pharmaceutical compositions containing them ZA892716B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8804870A FR2630110B1 (fr) 1988-04-13 1988-04-13 Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA892716B true ZA892716B (en) 1989-12-27

Family

ID=9365267

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892716A ZA892716B (en) 1988-04-13 1989-04-13 Heteroarotinoid derivatives,processes for preparing them and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4975455A (de)
EP (1) EP0338895B1 (de)
JP (1) JPH01305078A (de)
AT (1) ATE80881T1 (de)
AU (1) AU610379B2 (de)
CA (1) CA1326674C (de)
DE (1) DE68902946T2 (de)
DK (1) DK179289A (de)
ES (1) ES2035598T3 (de)
FR (1) FR2630110B1 (de)
GR (1) GR3006480T3 (de)
IE (1) IE64357B1 (de)
NZ (1) NZ228716A (de)
OA (1) OA09114A (de)
PT (1) PT90261B (de)
ZA (1) ZA892716B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5250547A (en) * 1991-08-29 1993-10-05 Syntex (U.S.A.) Inc. Benzopyran derivatives
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
JPH0852659A (ja) * 1994-08-08 1996-02-27 Tousetsu Denki Kk バイス
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH651034A5 (de) * 1982-05-12 1985-08-30 Hoffmann La Roche Chroman-, thiochroman- oder 1,2,3,4-tetrahydrochinolinderivate und ihre verwendung als arzneimittel-wirkstoffe.
US4808597A (en) * 1983-07-05 1989-02-28 Pfizer Inc. Method for inhibiting the degradation of cartilage
JPS60178815A (ja) * 1984-02-24 1985-09-12 Rikagaku Kenkyusho 制癌剤
US4826984A (en) * 1984-04-09 1989-05-02 The Board Of Regents For The Oklahoma Agricultural And Mechanical College Acting For And On Behalf Of Oklahoma State University Heteroarotinoid compounds as anticancer agents
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant

Also Published As

Publication number Publication date
AU610379B2 (en) 1991-05-16
GR3006480T3 (de) 1993-06-21
IE891161L (en) 1989-10-13
PT90261A (pt) 1989-11-10
CA1326674C (fr) 1994-02-01
NZ228716A (en) 1990-11-27
JPH01305078A (ja) 1989-12-08
DE68902946D1 (de) 1992-10-29
PT90261B (pt) 1994-07-29
FR2630110A1 (fr) 1989-10-20
AU3265989A (en) 1989-12-21
US4975455A (en) 1990-12-04
DE68902946T2 (de) 1993-04-29
EP0338895B1 (de) 1992-09-23
IE64357B1 (en) 1995-07-26
OA09114A (fr) 1991-10-31
JPH0585550B2 (de) 1993-12-07
ES2035598T3 (es) 1993-04-16
DK179289D0 (da) 1989-04-13
ATE80881T1 (de) 1992-10-15
DK179289A (da) 1989-10-14
EP0338895A1 (de) 1989-10-25
FR2630110B1 (fr) 1990-07-27

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