PT88850B - Processo de preparacao de vacina e de composicao contra a septicemia por e. coli em aves domesticas - Google Patents
Processo de preparacao de vacina e de composicao contra a septicemia por e. coli em aves domesticas Download PDFInfo
- Publication number
- PT88850B PT88850B PT88850A PT8885088A PT88850B PT 88850 B PT88850 B PT 88850B PT 88850 A PT88850 A PT 88850A PT 8885088 A PT8885088 A PT 8885088A PT 88850 B PT88850 B PT 88850B
- Authority
- PT
- Portugal
- Prior art keywords
- pili
- coli
- eli
- vaccine
- chickens
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims abstract description 24
- 206010040047 Sepsis Diseases 0.000 title claims abstract description 10
- 238000000034 method Methods 0.000 title claims description 15
- 239000000203 mixture Substances 0.000 title claims description 10
- 208000013223 septicemia Diseases 0.000 title claims description 8
- 238000002360 preparation method Methods 0.000 title claims description 7
- 241000588724 Escherichia coli Species 0.000 claims abstract description 33
- 230000002163 immunogen Effects 0.000 claims abstract description 16
- 238000004519 manufacturing process Methods 0.000 claims abstract description 10
- 244000144977 poultry Species 0.000 claims abstract description 10
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- 102000004169 proteins and genes Human genes 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 8
- 230000029142 excretion Effects 0.000 claims description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 3
- 239000002671 adjuvant Substances 0.000 claims description 3
- 239000003995 emulsifying agent Substances 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 239000000470 constituent Substances 0.000 claims description 2
- 239000006174 pH buffer Substances 0.000 claims description 2
- 241000287828 Gallus gallus Species 0.000 description 40
- 235000013330 chicken meat Nutrition 0.000 description 37
- 210000002966 serum Anatomy 0.000 description 16
- 241000894006 Bacteria Species 0.000 description 14
- 241000271566 Aves Species 0.000 description 11
- 238000002255 vaccination Methods 0.000 description 11
- 230000003053 immunization Effects 0.000 description 9
- 238000002649 immunization Methods 0.000 description 9
- 238000002347 injection Methods 0.000 description 9
- 239000007924 injection Substances 0.000 description 9
- 235000013594 poultry meat Nutrition 0.000 description 8
- 235000001014 amino acid Nutrition 0.000 description 7
- 150000001413 amino acids Chemical class 0.000 description 7
- 239000012634 fragment Substances 0.000 description 7
- 208000015181 infectious disease Diseases 0.000 description 7
- 108090000765 processed proteins & peptides Proteins 0.000 description 7
- 238000002965 ELISA Methods 0.000 description 6
- 230000000890 antigenic effect Effects 0.000 description 6
- 229920001184 polypeptide Polymers 0.000 description 6
- 102000004196 processed proteins & peptides Human genes 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 241000282414 Homo sapiens Species 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- 235000013601 eggs Nutrition 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 230000001681 protective effect Effects 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 239000000304 virulence factor Substances 0.000 description 4
- 230000007923 virulence factor Effects 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 241000282412 Homo Species 0.000 description 3
- 210000004712 air sac Anatomy 0.000 description 3
- 239000007478 blood agar base Substances 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 210000002969 egg yolk Anatomy 0.000 description 3
- 230000035931 haemagglutination Effects 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 239000004816 latex Substances 0.000 description 3
- 229920000126 latex Polymers 0.000 description 3
- 230000008506 pathogenesis Effects 0.000 description 3
- 230000009257 reactivity Effects 0.000 description 3
- 229920001817 Agar Polymers 0.000 description 2
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 2
- 101000801195 Homo sapiens TLE family member 5 Proteins 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 108010001267 Protein Subunits Proteins 0.000 description 2
- 102000002067 Protein Subunits Human genes 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 230000004520 agglutination Effects 0.000 description 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 2
- 235000011130 ammonium sulphate Nutrition 0.000 description 2
- 238000000546 chi-square test Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 150000002016 disaccharides Chemical class 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 235000013345 egg yolk Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 102000056245 human TLE5 Human genes 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000002480 mineral oil Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 210000000115 thoracic cavity Anatomy 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 208000019206 urinary tract infection Diseases 0.000 description 2
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 1
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- 108010042708 Acetylmuramyl-Alanyl-Isoglutamine Proteins 0.000 description 1
- 101100315627 Caenorhabditis elegans tyr-3 gene Proteins 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 238000012286 ELISA Assay Methods 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 101000619708 Homo sapiens Peroxiredoxin-6 Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241001430197 Mollicutes Species 0.000 description 1
- 241000283903 Ovis aries Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 206010071301 Perihepatitis Diseases 0.000 description 1
- 102100022239 Peroxiredoxin-6 Human genes 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 description 1
- 229960000723 ampicillin Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000006161 blood agar Substances 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000037029 cross reaction Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 229960003964 deoxycholic acid Drugs 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 208000018334 ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome Diseases 0.000 description 1
- 238000001493 electron microscopy Methods 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000000984 immunochemical effect Effects 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910000372 mercury(II) sulfate Inorganic materials 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- BSOQXXWZTUDTEL-ZUYCGGNHSA-N muramyl dipeptide Chemical compound OC(=O)CC[C@H](C(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1NC(C)=O BSOQXXWZTUDTEL-ZUYCGGNHSA-N 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 208000008494 pericarditis Diseases 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 229920000447 polyanionic polymer Polymers 0.000 description 1
- 102000040430 polynucleotide Human genes 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
- 239000002157 polynucleotide Substances 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- FHHPUSMSKHSNKW-SMOYURAASA-M sodium deoxycholate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 FHHPUSMSKHSNKW-SMOYURAASA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/826—Bacterial vaccine for avian species, e.g. poultry or other birds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8702536 | 1987-10-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT88850B true PT88850B (pt) | 1993-01-29 |
Family
ID=19850813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT88850A PT88850B (pt) | 1987-10-26 | 1988-10-25 | Processo de preparacao de vacina e de composicao contra a septicemia por e. coli em aves domesticas |
Country Status (19)
Country | Link |
---|---|
US (2) | US5208024A (en, 2012) |
EP (1) | EP0314224B1 (en, 2012) |
JP (1) | JP2718523B2 (en, 2012) |
KR (1) | KR970005333B1 (en, 2012) |
CN (1) | CN1038559C (en, 2012) |
AR (1) | AR241634A1 (en, 2012) |
AU (1) | AU610940B2 (en, 2012) |
CA (1) | CA1331445C (en, 2012) |
DD (1) | DD283331A5 (en, 2012) |
DE (1) | DE3871489D1 (en, 2012) |
DK (1) | DK175528B1 (en, 2012) |
ES (1) | ES2042718T3 (en, 2012) |
GR (1) | GR3005517T3 (en, 2012) |
HU (1) | HU203673B (en, 2012) |
IE (1) | IE60324B1 (en, 2012) |
NZ (1) | NZ226677A (en, 2012) |
PT (1) | PT88850B (en, 2012) |
YU (1) | YU47473B (en, 2012) |
ZA (1) | ZA887694B (en, 2012) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830709A (en) * | 1989-10-27 | 1998-11-03 | Benson; Roger E. | Detection method for homologous portions of a class of substances |
ZA934199B (en) * | 1992-06-18 | 1994-01-10 | Akzo Nv | Carrier system against gnrh |
WO1994013811A1 (en) * | 1992-12-04 | 1994-06-23 | N.V. Innogenetics S.A. | New polypeptides, nucleic acid sequences encoding them, and their use to prevent the adhesion of f107-fimbriated bacteria |
US5403582A (en) * | 1993-01-21 | 1995-04-04 | Nippon Zeon Co., Ltd. | Vaccine comprising fowlpox virus recombinants expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus |
WO1996000233A1 (en) * | 1994-06-24 | 1996-01-04 | Children's Hospital And Medical Center | Escherichia coli o157:h7 epithelial adhesin |
US5914114A (en) * | 1995-06-02 | 1999-06-22 | The United States Of America As Represented By The Secretary Of The Army | Method of raising antibodies against E. coli of the family CS4-CFA/I |
US6399074B1 (en) | 1998-07-24 | 2002-06-04 | Megan Health, Inc. | Live attenuated salmonella vaccines to control avian pathogens |
DE10203652B4 (de) * | 2002-01-30 | 2006-10-19 | Westfalia Separator Ag | Vollmantel-Schneckenzentrifuge mit einem Wehr |
CN101948538A (zh) * | 2010-10-19 | 2011-01-19 | 郑州后羿制药有限公司 | 一种抗大肠杆菌的鸡卵黄抗体精制方法 |
US8926980B2 (en) * | 2011-07-11 | 2015-01-06 | Camas Incorporated | Compositions against bacterial toxins |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU559550B2 (en) * | 1981-03-09 | 1987-03-12 | Cetus Corporation | Vaccines |
JPS58131920A (ja) * | 1982-01-29 | 1983-08-06 | Nisshin Flour Milling Co Ltd | 鶏の大腸菌症の予防法 |
JPS58146596A (ja) * | 1982-02-25 | 1983-09-01 | Takeda Chem Ind Ltd | 組換えdna、それで形質転換させた微生物およびそれらの用途 |
WO1984003506A1 (en) * | 1983-03-08 | 1984-09-13 | Commw Serum Lab Commission | Antigenically active amino acid sequences |
US4736017A (en) * | 1984-04-30 | 1988-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Chemically defined vaccine against urinary infections |
US4740585A (en) * | 1984-07-30 | 1988-04-26 | The Board Of Trustees Of The Leland Stanford Junior University | Synthetic vaccine against urinary infections |
ES8705033A1 (es) * | 1984-12-04 | 1987-04-16 | Biotech Australia Pty Ltd | Un metodo para preparar una vacuna para uso en el tratamiento prevencion de diarrea porcina neonatol. |
DK41885A (da) * | 1985-01-31 | 1986-11-13 | Slagteriernes Forskningsinst | 987p-fimbrie-producerende mikroorganisme, vaccine til immunisering af grise samt fremgangsmaade til fremstilling af vaccinen |
US4725435A (en) * | 1986-06-18 | 1988-02-16 | Bactex, Inc. | Vaccine composition for immunization against urinary tract infection caused by E. coli |
DK0413378T3 (da) * | 1989-08-18 | 1995-05-15 | Akzo Nobel Nv | Escherichia coli vaccine |
-
1988
- 1988-10-11 ES ES88202268T patent/ES2042718T3/es not_active Expired - Lifetime
- 1988-10-11 EP EP88202268A patent/EP0314224B1/en not_active Expired - Lifetime
- 1988-10-11 DE DE8888202268T patent/DE3871489D1/de not_active Expired - Lifetime
- 1988-10-14 IE IE313088A patent/IE60324B1/en not_active IP Right Cessation
- 1988-10-14 ZA ZA887694A patent/ZA887694B/xx unknown
- 1988-10-17 CA CA000580289A patent/CA1331445C/en not_active Expired - Lifetime
- 1988-10-17 YU YU193688A patent/YU47473B/sh unknown
- 1988-10-21 NZ NZ226677A patent/NZ226677A/xx unknown
- 1988-10-25 HU HU885580A patent/HU203673B/hu unknown
- 1988-10-25 PT PT88850A patent/PT88850B/pt not_active IP Right Cessation
- 1988-10-25 KR KR1019880013903A patent/KR970005333B1/ko not_active Expired - Lifetime
- 1988-10-25 CN CN88107351A patent/CN1038559C/zh not_active Expired - Lifetime
- 1988-10-25 AU AU24329/88A patent/AU610940B2/en not_active Expired
- 1988-10-25 DK DK198805934A patent/DK175528B1/da not_active IP Right Cessation
- 1988-10-26 AR AR88312302A patent/AR241634A1/es active
- 1988-10-26 DD DD88321101A patent/DD283331A5/de unknown
- 1988-10-26 JP JP63270610A patent/JP2718523B2/ja not_active Expired - Lifetime
-
1991
- 1991-09-23 US US07/764,991 patent/US5208024A/en not_active Expired - Lifetime
-
1992
- 1992-08-26 GR GR920401861T patent/GR3005517T3/el unknown
-
1994
- 1994-04-05 US US08/224,119 patent/US5593679A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR890006253A (ko) | 1989-06-12 |
AU610940B2 (en) | 1991-05-30 |
CN1038559C (zh) | 1998-06-03 |
EP0314224B1 (en) | 1992-05-27 |
AU2432988A (en) | 1989-04-27 |
HUT48122A (en) | 1989-05-29 |
CA1331445C (en) | 1994-08-16 |
DD283331A5 (de) | 1990-10-10 |
EP0314224A1 (en) | 1989-05-03 |
GR3005517T3 (en, 2012) | 1993-06-07 |
JP2718523B2 (ja) | 1998-02-25 |
JPH01149734A (ja) | 1989-06-12 |
ZA887694B (en) | 1989-06-28 |
DK175528B1 (da) | 2004-11-22 |
IE60324B1 (en) | 1994-06-29 |
DK593488D0 (da) | 1988-10-25 |
ES2042718T3 (es) | 1993-12-16 |
YU47473B (sh) | 1995-10-03 |
CN1033008A (zh) | 1989-05-24 |
DE3871489D1 (de) | 1992-07-02 |
DK593488A (da) | 1989-04-27 |
AR241634A1 (es) | 1992-10-30 |
HU203673B (en) | 1991-09-30 |
IE883130L (en) | 1989-04-26 |
US5593679A (en) | 1997-01-14 |
NZ226677A (en) | 1990-09-26 |
YU193688A (en) | 1990-06-30 |
KR970005333B1 (ko) | 1997-04-15 |
US5208024A (en) | 1993-05-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2279511T3 (es) | Inmunizacion activa utilizando una proteina receptor de sideroforo. | |
JP2640525B2 (ja) | 無毒の微生物とその使用 | |
CN101522210B (zh) | 增强免疫应答的组合物和方法 | |
TW204353B (en, 2012) | ||
JPS61502957A (ja) | 大腸菌のlt―bエンテロトキシンサブユニットと莢膜ポリマーとの免疫原性結合体 | |
JPS58126815A (ja) | 抗原性遺伝子ワクチン | |
HU211031B (en) | Method for preparation of actinobacillus pleuropneumoniae vaccine | |
PT88850B (pt) | Processo de preparacao de vacina e de composicao contra a septicemia por e. coli em aves domesticas | |
PT749321E (pt) | Imunização activa da utilização de uma proteina receptora de sideroforos | |
EP0287206A1 (en) | Vaccine against pasteurella | |
DE69110997T2 (de) | Haemophilus Paragallinarum-Impfstoffe. | |
CN104470539A (zh) | 睡眠嗜组织菌的外膜蛋白及其方法 | |
JPH06505730A (ja) | ヒトにおいてエンテロトキシン産生大腸菌により起こる腸感染症/下痢に対して接種するためのホルマリン殺菌したコロニー形成因子抗原(cfa)−発現性大腸菌の調製および使用 | |
CN108774628B (zh) | 合成致新生儿脑膜炎大肠杆菌糖蛋白结合疫苗的大肠杆菌工程菌及用途 | |
BR112015010364B1 (pt) | Vacinas atenuadas de mannheimia haemolytica e métodos de produção e uso | |
WO1993010815A1 (en) | Non-capsulated mutants of bacteria useful as vaccines | |
Chanteloup et al. | Serological conservation and location of the adhesin of avian Escherichia coli type 1 fimbriae | |
Jacob et al. | Identification of a 33 kDa antigen associated with an adhesive and colonizing strain of Vibrio cholerae El Tor and its role in protection | |
Vandemaele et al. | Immunization with the biologically active lectin domain of PapGII induces strong adhesion-inhibiting antibody responses but not protection against avian pathogenic Escherichia coli | |
JPH09505085A (ja) | パスツレラ科抗原および関連ワクチン | |
TW200418874A (en) | Passive vaccine for the prevention of campylobacter colonization, and its preparation method | |
RU2683027C2 (ru) | Поливалентная иммунизирующая и/или терапевтическая композиция для применения при бактериальных инфекциях или пищевом отравлении, в частности сальмонеллёзе, способ получения этой композиции, её применение и вакцина, содержащая эту композицию | |
CN111825774B (zh) | 一种猪致病性大肠杆菌双价ltb毒素及制备工艺和应用 | |
Elsheikha et al. | Therapeutic efficacy of chicken egg yolk immunoglobulins against Mycoplasma gallisepticum infection in chickens | |
Viret et al. | Bivalent vaccines against bacterial enteropathogens: construction of live attenuated vaccine strains with two O-serotype specificities |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19920714 |
|
PC4A | Transfer of assignment |
Owner name: INTERVET INTERNATIONAL B.V., NL Effective date: 20061114 |
|
MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20081025 |