PT86870A - Pharmaceutical tablet pharmaceutical granulate and process for their preparation - Google Patents

Pharmaceutical tablet pharmaceutical granulate and process for their preparation

Info

Publication number
PT86870A
PT86870A PT86870A PT8687088A PT86870A PT 86870 A PT86870 A PT 86870A PT 86870 A PT86870 A PT 86870A PT 8687088 A PT8687088 A PT 8687088A PT 86870 A PT86870 A PT 86870A
Authority
PT
Portugal
Prior art keywords
pharmaceutical
preparation
granulate
tablet
pharmaceutical tablet
Prior art date
Application number
PT86870A
Other languages
English (en)
Other versions
PT86870B (pt
Inventor
Margaretha Olthoff
Leonardus Wilhelmus Theod Boer
Piet Johannes Akkerboom
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8197583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT86870(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of PT86870A publication Critical patent/PT86870A/pt
Publication of PT86870B publication Critical patent/PT86870B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT86870A 1987-03-02 1988-03-01 Processo para a preparacao de um granulado e de um comprimido a base de um antibiotico de beta-lactama PT86870B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87200357 1987-03-02

Publications (2)

Publication Number Publication Date
PT86870A true PT86870A (pt) 1988-04-01
PT86870B PT86870B (pt) 1992-05-29

Family

ID=8197583

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86870A PT86870B (pt) 1987-03-02 1988-03-01 Processo para a preparacao de um granulado e de um comprimido a base de um antibiotico de beta-lactama

Country Status (16)

Country Link
US (1) US4950484A (pt)
EP (1) EP0281200B1 (pt)
JP (1) JPS63301820A (pt)
KR (1) KR960009182B1 (pt)
CN (1) CN1036763C (pt)
AU (1) AU603870B2 (pt)
CA (1) CA1338467C (pt)
DE (1) DE3887179T2 (pt)
DK (1) DK175508B1 (pt)
ES (1) ES2061623T3 (pt)
FI (1) FI94214C (pt)
IE (1) IE70907B1 (pt)
IL (1) IL85594A (pt)
NO (1) NO174996C (pt)
NZ (1) NZ223711A (pt)
PT (1) PT86870B (pt)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0319074B1 (en) * 1987-11-30 1992-01-29 Brocades Pharma B.V. Pharmaceutical composition and process for its preparation
US5211958A (en) * 1987-11-30 1993-05-18 Gist-Brocades, N.V. Pharmaceutical composition and process for its preparation
EP0330284B1 (en) * 1988-02-25 1994-07-27 Yamanouchi Europe B.V. Process for the preparation of a pharmaceutical granulate
FR2638971B1 (fr) * 1988-11-15 1993-01-08 Vacher Dominique Comprime a delitement et/ou dissolution instantane
GB9007945D0 (en) * 1990-04-07 1990-06-06 Beecham Group Plc Pharmaceutical formulation
US5814337A (en) * 1992-10-07 1998-09-29 Beecham Group Plc Pharmaceutical formulation
CA2039742A1 (en) * 1990-04-23 1991-10-24 Andrew B. Dennis Tablet composition and method for problem pharmaceutical materials
DK0481294T4 (da) * 1990-10-19 2001-06-18 Spirig Ag Fast, hurtigt-opløseligt lægemiddelpræparat indeholdende N-acetylcystein
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
NL9220009A (nl) * 1991-01-30 1993-11-01 Wellcome Found In water-dispergeerbare tabletten.
US5861172A (en) * 1991-05-08 1999-01-19 Laboratorios Beecham Sa Pharmaceutical formulations of compacted granulates of β-lactam antibiotics
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
BR9607189A (pt) * 1995-02-08 1997-11-11 Yamanouchi Europ Bv Formas de dosagem oral contendo um antibiótico de b-lactama
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
AR004510A1 (es) 1995-09-07 1998-12-16 Smithkline Beecham Plc Composiciones que comprenden amoxicilina y clavulanato, procedimientos para su preparacion y el uso de las composiciones para la fabricacion de unmedicamento
ATE216887T1 (de) * 1996-02-29 2002-05-15 Fujisawa Pharmaceutical Co Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung
TWI225402B (en) 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407214B (de) * 1996-03-13 2001-01-25 Biochemie Gmbh Verfahren zur herstellung von hilfsstoffefreien agglomeraten aus beta-lactamantibiotika
US5837292A (en) * 1996-07-03 1998-11-17 Yamanouchi Europe B.V. Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
US6242006B1 (en) 1996-07-16 2001-06-05 Gist-Brocades B.V. β-lactam granules free of organic solvents
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
CN1268888A (zh) * 1997-08-29 2000-10-04 Dsm公司 不含赋形剂的颗粒
US6129932A (en) * 1997-09-05 2000-10-10 Merck & Co., Inc. Compositions for inhibiting platelet aggregation
WO1999018965A1 (en) * 1997-10-10 1999-04-22 Yamanouchi Europe B.V. Oral compositions containing a cephalosporin antibiotic
PL334517A1 (en) * 1997-11-17 2000-02-28 Gist Brocades Bv Clavulate and one or more of exicipients containing granules
HUP0104951A2 (en) * 1998-09-25 2002-06-29 Delsys Pharmaceutical Corp Liquid pharmaceutical for oral delivery and process for its preparation
US6692779B2 (en) * 1999-03-26 2004-02-17 The Pillsbury Company Food products with biocontrol preservation
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) * 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US20020006433A1 (en) * 1999-04-29 2002-01-17 Nigel P. Davidson Pharmaceutical formulations
US6716453B1 (en) * 1999-05-20 2004-04-06 Verion, Inc. Method for increasing the active loading of compressible composition forms
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
AR025587A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones en dispersion que contienen inhibidores de lipasa
AR028253A1 (es) * 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
WO2002030392A2 (en) 2000-10-12 2002-04-18 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US6544552B2 (en) 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
EP1285649A1 (en) * 2001-08-23 2003-02-26 Cimex AG Bilayered dispersible tablet formulation comprising amoxycillin and clavulanate in separate layers
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
RU2004123621A (ru) * 2002-02-01 2005-04-10 Пфайзер Продактс Инк. (Us) Лекарственные формы с немедленным высвобождением, содержащие твердые дисперсии лекарств
US20050147666A1 (en) * 2002-03-06 2005-07-07 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
KR20050005437A (ko) 2002-04-09 2005-01-13 플라멜 테크놀로지스 아목시실린의 변형 방출을 위한 마이크로캡슐 수성 현탁액형태의 경구 제약학적 제제
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
KR20050062514A (ko) * 2002-07-16 2005-06-23 랜박시 래보러터리스 리미티드 경구 투여용 분산성 정제
AU2003247023A1 (en) * 2002-08-02 2004-02-25 Ranbaxy Laboratories Limited A process for the preparation of dispersible tablet of cephalexin
US8715734B2 (en) * 2004-02-24 2014-05-06 Sandoz Ag Amoxicilline instant granulate
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
US20050244343A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Oral care products comprising silica
WO2006012536A2 (en) 2004-07-22 2006-02-02 Ritter Andrew J Methods and compositions for treating lactose intolerance
WO2006072577A1 (en) * 2005-01-07 2006-07-13 Sandoz Ag Process for preparing granulates comprising amoxicillin
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
JP2010522135A (ja) 2006-10-09 2010-07-01 チャールストン ラボラトリーズ,インコーポレイテッド 医薬組成物
EP2170273B1 (de) * 2007-06-06 2014-11-26 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
US20090162434A1 (en) * 2007-12-21 2009-06-25 Disphar International Bv Mesalazine tablet
EP2240022B1 (en) 2008-01-09 2016-12-28 Charleston Laboratories, Inc. Bilayered tablets comprising oxycodone and promethazine
SG2014014435A (en) 2009-02-24 2014-07-30 Ritter Pharmaceuticals Inc Prebiotic formulations and methods of use
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
TR200909786A1 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Sefiksim içeren efervesan tablet ve granül formülasyonu.
WO2011137249A1 (en) 2010-04-28 2011-11-03 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
TR201010860A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefdinir formulasyonları için üretim yöntemi.
TR201009167A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefalosporin içeren farmasötik granüller.
WO2013122260A1 (en) * 2012-02-15 2013-08-22 Takeda Pharmaceutical Company Limited Tablet
WO2014023710A1 (en) 2012-08-07 2014-02-13 Sandoz Ag UNCOATED TABLET COMPRISING GRANULES INCLUDING A β-LACTAM ANTIBIOTIC AND HIGHLY DISPERSED SILICONE DIOXIDE
WO2014144407A1 (en) * 2013-03-15 2014-09-18 Braintree Laboratories, Inc. Dual use oral pharmaceutical composition tablets of sulfate saltes and methods of use thereof
US20170216328A1 (en) 2014-04-04 2017-08-03 Ritter Pharmaceuticals, Inc. Methods and compositions for microbiome alteration
CN106255512B (zh) 2014-04-21 2021-01-01 株式会社大赛璐 含有微小纤维状纤维素的崩解性颗粒组合物
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
JP2019507181A (ja) 2016-03-04 2019-03-14 チャールストン ラボラトリーズ,インコーポレイテッド 医薬組成物
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2019118984A2 (en) 2017-12-15 2019-06-20 Solarea Bio, Inc. Microbial compositions and methods for treating type 2 diabetes, obesity, and metabolic syndrome
US11980647B2 (en) 2018-09-05 2024-05-14 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
EP3846830A4 (en) 2018-09-05 2022-07-06 Solarea Bio, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MUSCULOSKELETAL DISEASES
WO2020257722A2 (en) 2019-06-19 2020-12-24 Solarea Bio, Inc. Microbial compositions and methods for producing upgraded probiotic assemblages
WO2023092150A1 (en) 2021-11-22 2023-05-25 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
US20230190834A1 (en) 2021-12-21 2023-06-22 Solarea Bio, Inc. Immunomodulatory compositions comprising microbial entities

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3870790A (en) * 1970-01-22 1975-03-11 Forest Laboratories Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
JPS5438167B2 (pt) * 1974-04-27 1979-11-19
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
JPS5620513A (en) * 1979-07-31 1981-02-26 Eisai Co Ltd Sugar-coated tablet containing fat-soluble drug
GB2058565B (en) * 1979-09-21 1983-12-07 Leo Pharm Prod Ltd Layer tablets
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
DE3134591A1 (de) * 1981-09-01 1983-03-10 Bayer Ag, 5090 Leverkusen Neue arzneimittelpraeparationen fuer glykosidhydrolasen-inhibitoren
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
DE3266580D1 (en) * 1981-12-02 1985-10-31 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4428951A (en) * 1982-04-22 1984-01-31 Fujisawa Pharmaceutical Co., Ltd. Long acting pharmaceutical composition
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
JPS59101423A (ja) * 1982-12-02 1984-06-12 Takada Seiyaku Kk 新規なニフエジピン固形製剤
JPS6038322A (ja) * 1983-08-11 1985-02-27 Fujisawa Pharmaceut Co Ltd ジヒドロピリジンa物質含有易溶性固形製剤
JPS6097919A (ja) * 1983-11-01 1985-05-31 Furointo Sangyo Kk 圧縮成形用賦形剤の製造方法
NL8400911A (nl) * 1984-03-22 1985-10-16 Dagra Nv Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat.
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets
US4851233A (en) * 1986-10-06 1989-07-25 Warner-Lambert Company Sustained release formulations
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

Also Published As

Publication number Publication date
AU1252088A (en) 1988-09-01
KR880010757A (ko) 1988-10-24
DE3887179D1 (de) 1994-03-03
JPS63301820A (ja) 1988-12-08
ES2061623T3 (es) 1994-12-16
CN88101104A (zh) 1988-12-21
IE70907B1 (en) 1997-01-15
CN1036763C (zh) 1997-12-24
DK175508B1 (da) 2004-11-15
NO880904L (no) 1988-09-05
FI880928A (fi) 1988-09-03
DE3887179T2 (de) 1994-06-16
FI94214C (fi) 1995-08-10
PT86870B (pt) 1992-05-29
DK108888A (da) 1988-09-03
FI880928A0 (fi) 1988-02-29
NO880904D0 (no) 1988-03-01
NO174996C (no) 1994-08-17
EP0281200B1 (en) 1994-01-19
AU603870B2 (en) 1990-11-29
NO174996B (no) 1994-05-09
DK108888D0 (da) 1988-03-01
KR960009182B1 (ko) 1996-07-16
IE880584L (en) 1988-09-02
US4950484A (en) 1990-08-21
IL85594A (en) 1992-11-15
NZ223711A (en) 1989-08-29
EP0281200A1 (en) 1988-09-07
FI94214B (fi) 1995-04-28
CA1338467C (en) 1996-07-23

Similar Documents

Publication Publication Date Title
PT86870A (pt) Pharmaceutical tablet pharmaceutical granulate and process for their preparation
HUT54491A (en) Quickly soluble pharmaceutical unit dosage and process for producing same
DK89090D0 (da) Farmaceutisk praeparat
NO177038C (no) Fremgangsmåte for fremstilling av et farmasöytisk doseringssystem
PT88557A (pt) Process for the production of pharmaceutical compositions for sustained and controlled release of drug comprising water-insoluble polypeptides
GB2149413B (en) Sustained release pharmaceutical tablets and process for the preparation thereof
LV10184A (lv) Tabletejama medikamenta izgatavosanas panemiens
HUT51272A (en) Process for producing thiadiazin derivatives and pharmaceutical composirions containing them
ATA119188A (de) Pharmazeutische granulate und verfahren zu ihrer herstellung
PT86986A (pt) Substituted 9-amino-tetrahydroacridines and related compounds a process for their preparation and their use as medicaments
DK705488A (da) Farmaceutisk praeparat
PT87237A (pt) Process for the preparation of bifunctional proteins and of pharmaceutical compounds containing them
DK287188D0 (da) Cephalosporinforbindelser og farmaceutisk praeparat deraf
PT87243A (pt) Process for the preparation of aliphatic carboxamides and of pharmaceutical compounds containing them
EP0347748A3 (en) Pharmaceutical granules and tablets made therefrom
DK96394A (da) 5-Halogenalkylidinimono-1-arylpyrazoler og fremgangsmåde til fremstilling deraf
NO176746C (no) Fremgangsmåte for fremstilling av en tablett med sympatomimetikum og piperidinoalkanol i adskilte soner
DK139388D0 (da) Farmaceutisk praeparat
DK259586D0 (da) Farmaceutisk tablet
DK276288D0 (da) Farmaceutisk praeparat
PT86642A (pt) Arylthiadiazolylsulfonamides and derivatives a process for thir preparation and their use as medicaments
PT87593A (pt) Process for the preparation of nucleosides and of pharmaceutical compounds containing them
AU106236S (en) Pharmaceutical tablet
DK580288A (da) Farmaceutisk praeparat indeholdende imidazol-2-thioncarboxamider
PT87573A (pt) Process for the preparation of amidas pyrazine and of pharmaceutical compounds containing them

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19911127

PC3A Transfer or assignment

Free format text: 920416 BROCADES PHARMA B.V. NL

PD3A Change of proprietorship