PT86870A - Pharmaceutical tablet pharmaceutical granulate and process for their preparation - Google Patents

Pharmaceutical tablet pharmaceutical granulate and process for their preparation

Info

Publication number
PT86870A
PT86870A PT86870A PT8687088A PT86870A PT 86870 A PT86870 A PT 86870A PT 86870 A PT86870 A PT 86870A PT 8687088 A PT8687088 A PT 8687088A PT 86870 A PT86870 A PT 86870A
Authority
PT
Portugal
Prior art keywords
pharmaceutical
preparation
granulate
tablet
pharmaceutical tablet
Prior art date
Application number
PT86870A
Other languages
English (en)
Other versions
PT86870B (pt
Inventor
Margaretha Olthoff
Leonardus Wilhelmus Theod Boer
Piet Johannes Akkerboom
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8197583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT86870(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of PT86870A publication Critical patent/PT86870A/pt
Publication of PT86870B publication Critical patent/PT86870B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT86870A 1987-03-02 1988-03-01 Processo para a preparacao de um granulado e de um comprimido a base de um antibiotico de beta-lactama PT86870B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87200357 1987-03-02

Publications (2)

Publication Number Publication Date
PT86870A true PT86870A (pt) 1988-04-01
PT86870B PT86870B (pt) 1992-05-29

Family

ID=8197583

Family Applications (1)

Application Number Title Priority Date Filing Date
PT86870A PT86870B (pt) 1987-03-02 1988-03-01 Processo para a preparacao de um granulado e de um comprimido a base de um antibiotico de beta-lactama

Country Status (16)

Country Link
US (1) US4950484A (pt)
EP (1) EP0281200B1 (pt)
JP (1) JPS63301820A (pt)
KR (1) KR960009182B1 (pt)
CN (1) CN1036763C (pt)
AU (1) AU603870B2 (pt)
CA (1) CA1338467C (pt)
DE (1) DE3887179T2 (pt)
DK (1) DK175508B1 (pt)
ES (1) ES2061623T3 (pt)
FI (1) FI94214C (pt)
IE (1) IE70907B1 (pt)
IL (1) IL85594A (pt)
NO (1) NO174996C (pt)
NZ (1) NZ223711A (pt)
PT (1) PT86870B (pt)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0319074B1 (en) * 1987-11-30 1992-01-29 Brocades Pharma B.V. Pharmaceutical composition and process for its preparation
US5211958A (en) * 1987-11-30 1993-05-18 Gist-Brocades, N.V. Pharmaceutical composition and process for its preparation
ES2060737T3 (es) * 1988-02-25 1994-12-01 Yamanouchi Europ Bv Procedimiento de preparacion de un granulado farmaceutico.
FR2638971B1 (fr) * 1988-11-15 1993-01-08 Vacher Dominique Comprime a delitement et/ou dissolution instantane
US5814337A (en) * 1992-10-07 1998-09-29 Beecham Group Plc Pharmaceutical formulation
GB9007945D0 (en) * 1990-04-07 1990-06-06 Beecham Group Plc Pharmaceutical formulation
CA2039742A1 (en) * 1990-04-23 1991-10-24 Andrew B. Dennis Tablet composition and method for problem pharmaceutical materials
DK0481294T4 (da) * 1990-10-19 2001-06-18 Spirig Ag Fast, hurtigt-opløseligt lægemiddelpræparat indeholdende N-acetylcystein
FR2671970B1 (fr) * 1991-01-30 1995-06-23 Wellcome Found Comprimes dispersables dans l'eau.
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
US5861172A (en) * 1991-05-08 1999-01-19 Laboratorios Beecham Sa Pharmaceutical formulations of compacted granulates of β-lactam antibiotics
GB9109862D0 (en) 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
ZA961018B (en) * 1995-02-08 1997-08-08 Yamanouchi Europ Bv Oral dosage-forms containing a beta-lactam antibiotic.
US20030109503A1 (en) * 1995-06-06 2003-06-12 Smithkline Beecham P.L.C. Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics
NZ318282A (en) 1995-09-07 2000-01-28 Smithkline Beecham Corp Pharmaceutical formulation containing amoxycillin and clavulanate in a weight ratio of 12:1 and 20:1
CN1136853C (zh) * 1996-02-29 2004-02-04 藤泽药品工业株式会社 含β-内酰胺抗生素的片剂及其制备方法
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
AT407214B (de) * 1996-03-13 2001-01-25 Biochemie Gmbh Verfahren zur herstellung von hilfsstoffefreien agglomeraten aus beta-lactamantibiotika
US5837292A (en) * 1996-07-03 1998-11-17 Yamanouchi Europe B.V. Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
US6242006B1 (en) 1996-07-16 2001-06-05 Gist-Brocades B.V. β-lactam granules free of organic solvents
WO1998034598A2 (en) * 1997-02-07 1998-08-13 Gist-Brocades B.V. Homogeneous granulated formulations for dose sipping technology
US20030124187A1 (en) * 1997-02-14 2003-07-03 Smithkline Beecham Laboratoires Pharmaceutiques, Pharmaceutical formulations comprising amoxycillin and clavulanate
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
CN1268888A (zh) * 1997-08-29 2000-10-04 Dsm公司 不含赋形剂的颗粒
US6129932A (en) * 1997-09-05 2000-10-10 Merck & Co., Inc. Compositions for inhibiting platelet aggregation
WO1999018965A1 (en) * 1997-10-10 1999-04-22 Yamanouchi Europe B.V. Oral compositions containing a cephalosporin antibiotic
PL334517A1 (en) * 1997-11-17 2000-02-28 Gist Brocades Bv Clavulate and one or more of exicipients containing granules
IL141339A0 (en) * 1998-09-25 2002-03-10 Delsys Pharmaceutical Corp Liquid pharmaceutical for oral delivery
US6692779B2 (en) * 1999-03-26 2004-02-17 The Pillsbury Company Food products with biocontrol preservation
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US20020006433A1 (en) * 1999-04-29 2002-01-17 Nigel P. Davidson Pharmaceutical formulations
US6716453B1 (en) * 1999-05-20 2004-04-06 Verion, Inc. Method for increasing the active loading of compressible composition forms
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
AR025587A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones en dispersion que contienen inhibidores de lipasa
UY26615A1 (es) * 2000-03-16 2001-10-25 Pfizer Prod Inc Inhibidor de la glucogeno fosforilasa.
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
EP1330236A2 (en) 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Formulation containing amoxicillin
US6544552B2 (en) 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
EP1285649A1 (en) * 2001-08-23 2003-02-26 Cimex AG Bilayered dispersible tablet formulation comprising amoxycillin and clavulanate in separate layers
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
RU2004123621A (ru) * 2002-02-01 2005-04-10 Пфайзер Продактс Инк. (Us) Лекарственные формы с немедленным высвобождением, содержащие твердые дисперсии лекарств
EP1488811A1 (en) * 2002-03-06 2004-12-22 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
ATE407674T1 (de) 2002-04-09 2008-09-15 Flamel Tech Sa Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
ATE419840T1 (de) 2002-04-09 2009-01-15 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
AU2003249116A1 (en) * 2002-07-16 2004-02-02 Ranbaxy Laboratories Limited Dispersible tablets for oral administration
US20070014850A1 (en) * 2002-08-02 2007-01-18 Ramalingam Manikandan Process for the preparation of dispersible tablets of cephalexin
JP2007523125A (ja) * 2004-02-24 2007-08-16 サンド・アクチエンゲゼルシヤフト アモキシシリンインスタント顆粒
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
US20050244343A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Oral care products comprising silica
WO2006012536A2 (en) 2004-07-22 2006-02-02 Ritter Andrew J Methods and compositions for treating lactose intolerance
JP5227591B2 (ja) * 2005-01-07 2013-07-03 サンド・アクチエンゲゼルシヤフト アモキシシリンを含む粒剤の調製方法
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
JP2010522135A (ja) 2006-10-09 2010-07-01 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
KR20100033400A (ko) * 2007-06-06 2010-03-29 바스프 에스이 급속 붕해 정제의 제조를 위한 제약 제제
US20090162434A1 (en) * 2007-12-21 2009-06-25 Disphar International Bv Mesalazine tablet
CA3066426A1 (en) 2008-01-09 2009-07-16 Charleston Laboratories, Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
US8785160B2 (en) 2009-02-24 2014-07-22 Ritter Pharmaceuticals, Inc. Prebiotic formulations and methods of use
SG2014014435A (en) 2009-02-24 2014-07-30 Ritter Pharmaceuticals Inc Prebiotic formulations and methods of use
WO2011006012A1 (en) 2009-07-08 2011-01-13 Charleston Laboratories Inc. Pharmaceutical compositions
TR200909786A1 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Sefiksim içeren efervesan tablet ve granül formülasyonu.
TR201010860A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefdinir formulasyonları için üretim yöntemi.
TR201009167A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefalosporin içeren farmasötik granüller.
JP6077555B2 (ja) * 2012-02-15 2017-02-08 武田薬品工業株式会社 錠剤
EP2882423A1 (en) 2012-08-07 2015-06-17 Sandoz AG Uncoated tablet comprising granules including a -lactam antibiotic and highly dispersed silicone dioxide
CN105142617B (zh) 2013-03-15 2018-08-03 布伦特里实验室公司 双用途硫酸盐口服药物组合物片剂及其使用方法
WO2015153841A1 (en) 2014-04-04 2015-10-08 Ritter Pharmaceuticals, Inc. Methods and compositions for microbiome alteration
KR102415876B1 (ko) * 2014-04-21 2022-06-30 주식회사 다이셀 미소섬유상 셀룰로오스를 포함하는 붕해성 입자 조성물
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2019118984A2 (en) 2017-12-15 2019-06-20 Solarea Bio, Inc. Microbial compositions and methods for treating type 2 diabetes, obesity, and metabolic syndrome
EP3846830A4 (en) 2018-09-05 2022-07-06 Solarea Bio, Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MUSCULOSKELETAL DISEASES
US11980647B2 (en) 2018-09-05 2024-05-14 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
WO2020257722A2 (en) 2019-06-19 2020-12-24 Solarea Bio, Inc. Microbial compositions and methods for producing upgraded probiotic assemblages
CA3238788A1 (en) 2021-11-22 2023-05-25 Eric Michael Schott Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
US20230190834A1 (en) 2021-12-21 2023-06-22 Solarea Bio, Inc. Immunomodulatory compositions comprising microbial entities

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3870790A (en) * 1970-01-22 1975-03-11 Forest Laboratories Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
JPS5438167B2 (pt) * 1974-04-27 1979-11-19
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
JPS5620513A (en) * 1979-07-31 1981-02-26 Eisai Co Ltd Sugar-coated tablet containing fat-soluble drug
GB2058565B (en) * 1979-09-21 1983-12-07 Leo Pharm Prod Ltd Layer tablets
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
DE3134591A1 (de) * 1981-09-01 1983-03-10 Bayer Ag, 5090 Leverkusen Neue arzneimittelpraeparationen fuer glykosidhydrolasen-inhibitoren
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
DE3266580D1 (en) * 1981-12-02 1985-10-31 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4428951A (en) * 1982-04-22 1984-01-31 Fujisawa Pharmaceutical Co., Ltd. Long acting pharmaceutical composition
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
JPS59101423A (ja) * 1982-12-02 1984-06-12 Takada Seiyaku Kk 新規なニフエジピン固形製剤
JPS6038322A (ja) * 1983-08-11 1985-02-27 Fujisawa Pharmaceut Co Ltd ジヒドロピリジンａ物質含有易溶性固形製剤
JPS6097919A (ja) * 1983-11-01 1985-05-31 Furointo Sangyo Kk 圧縮成形用賦形剤の製造方法
NL8400911A (nl) * 1984-03-22 1985-10-16 Dagra Nv Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat.
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets
US4851233A (en) * 1986-10-06 1989-07-25 Warner-Lambert Company Sustained release formulations
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

Also Published As

Publication number Publication date
IL85594A (en) 1992-11-15
FI94214B (fi) 1995-04-28
JPS63301820A (ja) 1988-12-08
NO174996B (no) 1994-05-09
CN88101104A (zh) 1988-12-21
CN1036763C (zh) 1997-12-24
NO174996C (no) 1994-08-17
DK175508B1 (da) 2004-11-15
FI94214C (fi) 1995-08-10
PT86870B (pt) 1992-05-29
FI880928A0 (fi) 1988-02-29
AU603870B2 (en) 1990-11-29
US4950484A (en) 1990-08-21
DE3887179D1 (de) 1994-03-03
IE880584L (en) 1988-09-02
DK108888D0 (da) 1988-03-01
NO880904D0 (no) 1988-03-01
KR960009182B1 (ko) 1996-07-16
DK108888A (da) 1988-09-03
AU1252088A (en) 1988-09-01
FI880928A (fi) 1988-09-03
ES2061623T3 (es) 1994-12-16
CA1338467C (en) 1996-07-23
NZ223711A (en) 1989-08-29
DE3887179T2 (de) 1994-06-16
IE70907B1 (en) 1997-01-15
NO880904L (no) 1988-09-05
KR880010757A (ko) 1988-10-24
EP0281200B1 (en) 1994-01-19
EP0281200A1 (en) 1988-09-07

Similar Documents

Publication Publication Date Title
PT86870A (pt) Pharmaceutical tablet pharmaceutical granulate and process for their preparation
HUT54491A (en) Quickly soluble pharmaceutical unit dosage and process for producing same
DK89090D0 (da) Farmaceutisk praeparat
NO177038C (no) Fremgangsmåte for fremstilling av et farmasöytisk doseringssystem
GB2149413B (en) Sustained release pharmaceutical tablets and process for the preparation thereof
LV10184A (lv) Tabletejama medikamenta izgatavosanas panemiens
HUT51272A (en) Process for producing thiadiazin derivatives and pharmaceutical composirions containing them
ATA119188A (de) Pharmazeutische granulate und verfahren zu ihrer herstellung
PT86986A (pt) Substituted 9-amino-tetrahydroacridines and related compounds a process for their preparation and their use as medicaments
DK705488D0 (da) Farmaceutisk praeparat
PT87237A (pt) Process for the preparation of bifunctional proteins and of pharmaceutical compounds containing them
DK287188D0 (da) Cephalosporinforbindelser og farmaceutisk praeparat deraf
PT87243A (pt) Process for the preparation of aliphatic carboxamides and of pharmaceutical compounds containing them
EP0347748A3 (en) Pharmaceutical granules and tablets made therefrom
DK96394A (da) 5-Halogenalkylidinimono-1-arylpyrazoler og fremgangsmåde til fremstilling deraf
NO176746C (no) Fremgangsmåte for fremstilling av en tablett med sympatomimetikum og piperidinoalkanol i adskilte soner
DK139388D0 (da) Farmaceutisk praeparat
DK259586A (da) Farmaceutisk tablet
DK276288D0 (da) Farmaceutisk praeparat
PT86642A (pt) Arylthiadiazolylsulfonamides and derivatives a process for thir preparation and their use as medicaments
PT87593A (pt) Process for the preparation of nucleosides and of pharmaceutical compounds containing them
AU106236S (en) Pharmaceutical tablet
FR2609246B3 (fr) Produits cosmetiques a base de spiruline et leur procede de preparation
DK580288D0 (da) Farmaceutisk praeparat indeholdende imidazol-2-thioncarboxamider
PT87573A (pt) Process for the preparation of amidas pyrazine and of pharmaceutical compounds containing them

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19911127

PC3A Transfer or assignment

Free format text: 920416 BROCADES PHARMA B.V. NL

PD3A Change of proprietorship