PT782449E - Processo de fabrico de unidades de dosagem por granulacao humida - Google Patents

Processo de fabrico de unidades de dosagem por granulacao humida

Info

Publication number
PT782449E
PT782449E PT95933401T PT95933401T PT782449E PT 782449 E PT782449 E PT 782449E PT 95933401 T PT95933401 T PT 95933401T PT 95933401 T PT95933401 T PT 95933401T PT 782449 E PT782449 E PT 782449E
Authority
PT
Portugal
Prior art keywords
pct
dosage units
humidity
manufacturing process
date
Prior art date
Application number
PT95933401T
Other languages
English (en)
Inventor
Pieter De Haan
Jocominus Antonius Ma Zwinkels
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of PT782449E publication Critical patent/PT782449E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT95933401T 1994-09-22 1995-09-19 Processo de fabrico de unidades de dosagem por granulacao humida PT782449E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94202728 1994-09-22

Publications (1)

Publication Number Publication Date
PT782449E true PT782449E (pt) 2003-07-31

Family

ID=8217217

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95933401T PT782449E (pt) 1994-09-22 1995-09-19 Processo de fabrico de unidades de dosagem por granulacao humida

Country Status (23)

Country Link
US (1) US5916593A (pt)
EP (1) EP0782449B1 (pt)
JP (1) JP4334616B2 (pt)
KR (1) KR100384264B1 (pt)
CN (1) CN1101681C (pt)
AT (1) ATE236639T1 (pt)
AU (1) AU700645B2 (pt)
BR (1) BR9509019B1 (pt)
CA (1) CA2200754C (pt)
CZ (1) CZ289081B6 (pt)
DE (1) DE69530308T2 (pt)
DK (1) DK0782449T3 (pt)
ES (1) ES2196079T3 (pt)
FI (1) FI118791B (pt)
HK (1) HK1002172A1 (pt)
HU (1) HU226619B1 (pt)
MX (1) MX9702162A (pt)
NO (1) NO311492B1 (pt)
NZ (1) NZ293606A (pt)
PL (1) PL181406B1 (pt)
PT (1) PT782449E (pt)
RU (1) RU2166936C2 (pt)
WO (1) WO1996009056A1 (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0955048A1 (en) * 1998-03-12 1999-11-10 Akzo Nobel N.V. Making dosage units using low shear granulation
IL128818A0 (en) * 1998-03-12 2000-01-31 Akzo Nobel Nv Making dosage units using low shear granulation
WO2000050041A1 (en) * 1999-02-24 2000-08-31 Akzo Nobel N.V. Pharmaceutical compositions containing a crystalline form of the progestagen-(17alpha)-17-hydroxy-11-methylene-19-nor-pregna-4,15-dien-20-yn-3-one (org 30659) and lactose
US6787531B1 (en) * 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
DK1380301T3 (da) * 1999-08-31 2009-04-20 Bayer Schering Pharma Ag Farmaceutisk sammensætning af ethinylestradiol og drospirenon til anvendelse som svangerskabsforebyggende middel
EP1216713A1 (en) * 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions of estrogen-cyclodextrin complexes
US20030027848A1 (en) * 2001-06-15 2003-02-06 Anne Billotte Stabilized formulations
DE10159120B4 (de) * 2001-12-01 2006-08-17 Lts Lohmann Therapie-Systeme Ag Steroidhormonhaltige transdermale therapeutische Systeme enthaltend Propylenglycolmonocaprylat und seine Verwendung
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
TW200403075A (en) * 2002-05-29 2004-03-01 Akzo Nobel Nv Progestagenic dosage units
BR0309691A (pt) 2002-12-20 2005-08-02 Hoffmann La Roche Formulação de ibandronato em alta dose
CZ298224B6 (cs) * 2003-04-29 2007-07-25 Pliva Istrazivanje I Razvoj D.O.O. Farmaceutická kompozice obsahující jako úcinnou látku ribavirin a zpusob její výroby
DK1670440T3 (da) * 2003-09-29 2014-07-07 Novo Nordisk As HRT formuleringer
EP1673071A1 (en) * 2003-09-29 2006-06-28 Novo Nordisk Femcare AG Improved stability of progestogen formulations
JP4412963B2 (ja) * 2003-10-10 2010-02-10 旭有機材工業株式会社 バルブ用樹脂製部材
JP2007532511A (ja) * 2004-04-09 2007-11-15 スミスクライン ビーチャム コーポレーション 低用量医薬品
US7846466B2 (en) * 2004-06-10 2010-12-07 Northwestern University Biodegradable scaffolds and uses thereof
KR20070072888A (ko) * 2004-10-25 2007-07-06 니뽄 다바코 산교 가부시키가이샤 용해성 및 안정성이 개선된 고형 제제 및 그의 제조 방법
WO2006078925A2 (en) * 2005-01-21 2006-07-27 Warner Chilcott Company, Inc. A tetracycline metal complex in a solid dosage form
KR20070094666A (ko) * 2005-02-25 2007-09-20 에프. 호프만-라 로슈 아게 약제 물질 분산성이 향상된 정제
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
CN101489563A (zh) * 2006-07-06 2009-07-22 拜耳先灵医药股份有限公司 用于避孕和预防先天性畸形风险的药物制剂
EP2293779A1 (en) * 2008-04-24 2011-03-16 Evestra, Inc. Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen
BRPI0917026A2 (pt) * 2008-08-08 2016-02-16 Mcneil Ppc Inc uso de sucralose como agente granulador
EP2349220B1 (en) * 2008-10-09 2012-07-25 Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi Using of organic solvents in wet granulation of moxifloxacin
US8945616B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
US8945615B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
JP2017001989A (ja) * 2015-06-11 2017-01-05 ニプロ株式会社 医薬組成物の製造方法及び医薬組成物
JP6759478B2 (ja) * 2019-02-13 2020-09-23 富士製薬工業株式会社 経口固形組成物、その製造方法、及びその製造方法によって得られた経口用錠剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3969502A (en) * 1972-04-14 1976-07-13 Schering Aktiengesellschaft Method for contraception by the administration of sequential contraceptive preparations
US4956182A (en) * 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
US5200197A (en) * 1989-11-16 1993-04-06 Alza Corporation Contraceptive pill
US5098714A (en) * 1989-11-16 1992-03-24 Alza Corporation Osmotic, oral dosage form for fertility control
IE62665B1 (en) * 1990-12-17 1995-02-22 Akzo Nv Contraceptive regimen
IE71202B1 (en) * 1990-12-17 1997-02-12 Akzo Nv Progestagen-only contraceptive
IE67345B1 (en) * 1991-03-12 1996-03-20 Akzo Nv Low dose dry pharmaceutical preparations
DE4229820C2 (de) * 1992-09-07 1998-12-03 Jenapharm Gmbh Pharmazeutische Zubereitung auf Gestagen-Basis
NZ262562A (en) * 1993-02-23 1996-04-26 Warner Lambert Co Preparation of solvent free pharmaceutical compositions
AU671706B2 (en) * 1993-03-05 1996-09-05 Akzo N.V. Use of a Pregnane Derivative
ZA939565B (en) * 1993-12-21 1994-08-11 Applied Analytical Ind Inc Method for preparing low dose pharmaceutical products.

Also Published As

Publication number Publication date
KR100384264B1 (ko) 2003-08-30
HU226619B1 (en) 2009-04-28
CA2200754C (en) 2008-04-15
HK1002172A1 (en) 1998-08-07
EP0782449B1 (en) 2003-04-09
WO1996009056A1 (en) 1996-03-28
US5916593A (en) 1999-06-29
DE69530308T2 (de) 2003-10-16
JPH10505846A (ja) 1998-06-09
NO971361D0 (no) 1997-03-21
KR970706001A (ko) 1997-11-03
MX9702162A (es) 1997-06-28
BR9509019B1 (pt) 2009-01-13
NO311492B1 (no) 2001-12-03
DK0782449T3 (da) 2003-08-04
CZ89997A3 (en) 1997-09-17
FI971172A (fi) 1997-03-20
CN1161650A (zh) 1997-10-08
JP4334616B2 (ja) 2009-09-30
NZ293606A (en) 1998-06-26
ATE236639T1 (de) 2003-04-15
NO971361L (no) 1997-05-21
FI118791B (fi) 2008-03-31
CA2200754A1 (en) 1996-03-28
HUT77611A (hu) 1998-06-29
FI971172A0 (fi) 1997-03-20
AU700645B2 (en) 1999-01-14
CN1101681C (zh) 2003-02-19
EP0782449A1 (en) 1997-07-09
RU2166936C2 (ru) 2001-05-20
BR9509019A (pt) 1997-12-30
AU3608295A (en) 1996-04-09
PL319373A1 (en) 1997-08-04
CZ289081B6 (cs) 2001-10-17
DE69530308D1 (de) 2003-05-15
ES2196079T3 (es) 2003-12-16
PL181406B1 (pl) 2001-07-31

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