PT721455E - Tetrahidropiridina-(ou 4-hidroxipiperidina) alquilazoles com uma actividade para os receptores sigma e/ou 5ht1a - Google Patents
Tetrahidropiridina-(ou 4-hidroxipiperidina) alquilazoles com uma actividade para os receptores sigma e/ou 5ht1aInfo
- Publication number
- PT721455E PT721455E PT95928478T PT95928478T PT721455E PT 721455 E PT721455 E PT 721455E PT 95928478 T PT95928478 T PT 95928478T PT 95928478 T PT95928478 T PT 95928478T PT 721455 E PT721455 E PT 721455E
- Authority
- PT
- Portugal
- Prior art keywords
- activity
- alkylazolides
- hydroxypiperidine
- sigma
- 5ht1a receptors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D521/00—Heterocyclic compounds containing unspecified hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9409443A FR2723091B1 (fr) | 1994-07-29 | 1994-07-29 | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
PT721455E true PT721455E (pt) | 2003-04-30 |
Family
ID=9465902
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95928478T PT721455E (pt) | 1994-07-29 | 1995-07-26 | Tetrahidropiridina-(ou 4-hidroxipiperidina) alquilazoles com uma actividade para os receptores sigma e/ou 5ht1a |
Country Status (22)
Country | Link |
---|---|
US (2) | US5731331A (pt) |
EP (1) | EP0721455B9 (pt) |
JP (2) | JP4035787B2 (pt) |
KR (1) | KR100389785B1 (pt) |
CN (1) | CN1120167C (pt) |
AT (1) | ATE229530T1 (pt) |
AU (1) | AU712479B2 (pt) |
BR (1) | BR9506292A (pt) |
CA (1) | CA2172986A1 (pt) |
CZ (1) | CZ293123B6 (pt) |
DE (1) | DE69529142T2 (pt) |
DK (1) | DK0721455T3 (pt) |
FI (1) | FI116386B (pt) |
FR (1) | FR2723091B1 (pt) |
HU (1) | HU220088B (pt) |
NO (1) | NO309379B1 (pt) |
NZ (1) | NZ291172A (pt) |
PL (1) | PL183766B1 (pt) |
PT (1) | PT721455E (pt) |
RU (1) | RU2168507C2 (pt) |
WO (1) | WO1996004287A1 (pt) |
ZA (1) | ZA956314B (pt) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
FR2742052B1 (fr) * | 1995-12-12 | 1998-04-10 | Esteve Labor Dr | Utilisation des derives 1-(4-(4-aryl (ou heteroaryl)-1-piper azinyl)-buty)-1h-azole pour le traitement de la depression, des troubles obsessifs compulsifs, l'apnee du sommeil, les dysfonctions sexuelles, l'emese et le mal des transports |
GB9613423D0 (en) * | 1996-06-26 | 1996-08-28 | Lilly Industries Ltd | Pharmaceutical compounds |
HUP9602763A3 (en) * | 1996-10-09 | 1999-05-28 | Egyt Gyogyszervegyeszeti Gyar | 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same |
US5919802A (en) * | 1997-12-05 | 1999-07-06 | Princeton University | Methods of preventing and/or treating temporal lobe epilepsy |
ES2151828B1 (es) * | 1998-07-10 | 2001-08-16 | Esteve Labor Dr | Empleo de derivados de tetrahidropiridinas (ohidroxi-piperidinas)-b utilazoles en la elaboracion de un medicamento para el tratamiento del dolor. |
US6046331A (en) * | 1998-12-17 | 2000-04-04 | Synaptic Pharmaceutical Corporation | Imidazolones and their use in treating benign prostatic hyperplasia and other disorders |
GB2355456A (en) | 1999-09-30 | 2001-04-25 | Merck & Co Inc | Novel arylhydantoin derivatives useful as alpha 1a adrenoceptor antagonists |
UA73981C2 (en) * | 2000-03-10 | 2005-10-17 | Merck Patent Gmbh | (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit |
DE10109867A1 (de) * | 2001-03-01 | 2002-09-05 | Abbott Gmbh & Co Kg | Verwendung von Triazolverbindungen zur Prophylaxe und Therapie neurodegenerativer Erkrankungen, Hirntrauma und zerebraler Ischämie |
DE10109866A1 (de) * | 2001-03-01 | 2002-09-05 | Abbott Gmbh & Co Kg | Triazolverbindungen und deren Verwendung zur Prophylaxe und Therapie neurodegenerativer Erkrankungen, Hirntrauma und zerebraler Ischämie |
EP1634873A1 (en) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Sigma receptor inhibitors |
ES2251317B1 (es) * | 2004-10-14 | 2007-03-16 | Laboratorios Del Dr. Esteve, S.A. | Inhibidores del receptor sigma. |
ES2251316B1 (es) * | 2004-10-14 | 2007-03-16 | Laboratorios Del Dr. Esteve, S.A. | Inhibidores del receptor sigma. |
BRPI0514736A (pt) | 2004-08-27 | 2008-06-24 | Esteve Labor Dr | inibidores do receptor sigma |
KR100893394B1 (ko) * | 2007-05-11 | 2009-04-17 | 한국화학연구원 | 아릴 피페리딘기-함유 이미다졸 유도체, 이의 제조방법 및이를 유효성분으로 포함하는 약학적 조성물 |
US8198307B2 (en) * | 2007-05-11 | 2012-06-12 | Korea Research Institute Of Chemical Technology | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same |
KR100895998B1 (ko) * | 2007-05-11 | 2009-05-07 | 한국화학연구원 | 아릴 피페리딘기-함유 이미다졸 유도체, 이의 제조방법 및이를 유효성분으로 포함하는 약학적 조성물 |
KR100871077B1 (ko) * | 2007-05-11 | 2008-11-28 | 한국화학연구원 | 아릴 피페리딘기-함유 이미다졸 유도체, 이의 제조방법 및이를 유효성분으로 포함하는 약학적 조성물 |
BR122021013836B1 (pt) | 2009-12-04 | 2022-05-24 | Sunovion Pharmaceuticals, Inc. | Composto e seu uso, composição farmacêutica |
JP2019523279A (ja) | 2016-07-29 | 2019-08-22 | サノビオン ファーマシューティカルズ インクSunovion Pharmaceuticals Inc. | 化合物および組成物ならびにそれらの使用 |
MX2019000980A (es) | 2016-07-29 | 2019-07-04 | Sunovion Pharmaceuticals Inc | Compuestos y composiciones y usos de los mismos. |
JP7146782B2 (ja) | 2017-02-16 | 2022-10-04 | サノビオン ファーマシューティカルズ インク | 統合失調症を処置する方法 |
CN109280030B (zh) * | 2017-07-19 | 2022-04-22 | 江苏恩华药业股份有限公司 | 苯骈氮杂烷基芳基哌嗪衍生物及在制备药物中的应用 |
MX2020000523A (es) | 2017-08-02 | 2020-08-20 | Sunovion Pharmaceuticals Inc | Compuestos de isocromano y usos de los mismos. |
CN118406063A (zh) | 2018-02-16 | 2024-07-30 | 赛诺维信制药公司 | 盐、晶型及其制备方法 |
US11136304B2 (en) | 2019-03-14 | 2021-10-05 | Sunovion Pharmaceuticals Inc. | Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
MX2022012833A (es) | 2020-04-14 | 2022-11-07 | Sunovion Pharmaceuticals Inc | (s)-(4,5-dihidro-7h-tieno[2,3-c]piran-7-il)-n-metilmetanamina para tratar trastornos neurologicos y psiquiatricos. |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3509153A (en) * | 1967-03-24 | 1970-04-28 | Miles Lab | 5-phenyl (or 5-phenylalkyl)-2-(omega-(4-phenyl-1-piperazinyl)alkyl)tetrazoles |
US3635982A (en) * | 1969-04-08 | 1972-01-18 | American Home Prod | Amino-substituted-quinoxalinyloxazolidines and -oxazines |
ES378315A1 (es) * | 1969-04-11 | 1972-06-01 | Robins Co Inc A H | Un procedimiento para la preparacion de 1 - (omega-susti- tuido-alcohil)-2-metilbenzimidazoles. |
JPS5011395B1 (pt) * | 1970-12-29 | 1975-04-30 | ||
NZ181256A (en) * | 1975-07-21 | 1978-04-28 | Janssen Pharmaceutica Nv | 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives |
US3981881A (en) * | 1975-08-14 | 1976-09-21 | E. R. Squibb & Sons, Inc. | 2-[(4-Phenyl-tetrahydropyridinyl)alkyl]-1H-isoindole-1,3(2H)-diones |
US3994904A (en) * | 1976-03-08 | 1976-11-30 | Miles Laboratories, Inc. | 3-Substituted -5-phenyl-5-pyridyl hydantoins |
JPS5746983A (en) * | 1980-09-04 | 1982-03-17 | Eisai Co Ltd | Theophylline derivative and its preparation |
JPS58150511A (ja) * | 1982-03-02 | 1983-09-07 | Eisai Co Ltd | テオフイリン誘導体を有効成分とする脳循環代謝改善剤 |
DE3364234D1 (en) * | 1982-03-02 | 1986-07-31 | Eisai Co Ltd | Antiphlogistic/antipyretic/analgesic pharmaceutical compositions containing theophylline derivatives as active ingredient |
US4539407A (en) * | 1983-12-13 | 1985-09-03 | American Home Products Corporation | β-Carboline anticonvulsants |
US4675403A (en) * | 1985-10-16 | 1987-06-23 | American Home Products Corporation | 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity |
US4754038A (en) * | 1987-02-26 | 1988-06-28 | American Home Products Corporation | Carboline histamine H1 antagonists |
DE69021855T2 (de) * | 1990-01-02 | 1996-02-29 | Fujisawa Pharmaceutical Co | Quinazolinderivate und ihre Herstellung. |
US5296487A (en) * | 1990-01-02 | 1994-03-22 | Fujisawa Pharmaceutical Co., Ltd. | Quinazoline derivatives and their preparation |
FR2672052B1 (fr) * | 1991-01-28 | 1995-05-24 | Esteve Labor Dr | Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments. |
JP3198117B2 (ja) * | 1990-02-07 | 2001-08-13 | サントリー株式会社 | ピロロアゼピン誘導体 |
US5149817A (en) * | 1990-03-05 | 1992-09-22 | Shionogi & Co., Ltd. | Teirahydropyridine derivatives |
JPH04211059A (ja) * | 1990-03-05 | 1992-08-03 | Shionogi & Co Ltd | 新規なテトラヒドロピリジン誘導体 |
FR2671972B1 (fr) * | 1991-01-25 | 1995-03-03 | Esteve Labor Dr | Utilisation de derives 1-h-azole-(omega-(4-(2-pyrimidinyl)-1-piperazinyl)-alkyl) pour la preparation de medicaments destines au traitement des troubles des fonctions cognitives. |
FR2673628B1 (fr) * | 1991-03-07 | 1993-07-09 | Esteve Labor Dr | Procede de preparation de derives d'aryl (ou heteroaryl)-piperazinyl-butyl-azoles. |
JP3219281B2 (ja) * | 1991-04-03 | 2001-10-15 | 聰 竹尾 | 心筋保護剤 |
DK148392D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Heterocykliske forbindelser |
WO1995003298A1 (en) * | 1993-07-19 | 1995-02-02 | Fujisawa Pharmaceutical Co., Ltd. | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST |
US5411960A (en) * | 1993-12-09 | 1995-05-02 | Bayer Aktiengesellschaft | Substituted pyrroloanthracenes and -diones |
FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
-
1994
- 1994-07-29 FR FR9409443A patent/FR2723091B1/fr not_active Expired - Fee Related
-
1995
- 1995-06-07 US US08/473,066 patent/US5731331A/en not_active Expired - Lifetime
- 1995-07-26 BR BR9506292A patent/BR9506292A/pt not_active IP Right Cessation
- 1995-07-26 RU RU96110883/04A patent/RU2168507C2/ru not_active IP Right Cessation
- 1995-07-26 PT PT95928478T patent/PT721455E/pt unknown
- 1995-07-26 CZ CZ1996926A patent/CZ293123B6/cs not_active IP Right Cessation
- 1995-07-26 PL PL95313716A patent/PL183766B1/pl not_active IP Right Cessation
- 1995-07-26 EP EP95928478A patent/EP0721455B9/fr not_active Expired - Lifetime
- 1995-07-26 CN CN95190813A patent/CN1120167C/zh not_active Expired - Fee Related
- 1995-07-26 CA CA002172986A patent/CA2172986A1/fr not_active Abandoned
- 1995-07-26 AT AT95928478T patent/ATE229530T1/de not_active IP Right Cessation
- 1995-07-26 DE DE69529142T patent/DE69529142T2/de not_active Expired - Lifetime
- 1995-07-26 KR KR1019960701606A patent/KR100389785B1/ko not_active IP Right Cessation
- 1995-07-26 DK DK95928478T patent/DK0721455T3/da active
- 1995-07-26 AU AU32225/95A patent/AU712479B2/en not_active Ceased
- 1995-07-26 NZ NZ291172A patent/NZ291172A/en unknown
- 1995-07-26 WO PCT/EP1995/002978 patent/WO1996004287A1/fr active IP Right Grant
- 1995-07-26 HU HU9600815A patent/HU220088B/hu not_active IP Right Cessation
- 1995-07-26 JP JP50617496A patent/JP4035787B2/ja not_active Expired - Fee Related
- 1995-07-28 ZA ZA956314A patent/ZA956314B/xx unknown
-
1996
- 1996-03-25 NO NO961207A patent/NO309379B1/no unknown
- 1996-03-28 FI FI961412A patent/FI116386B/fi not_active IP Right Cessation
-
1998
- 1998-02-26 US US09/031,024 patent/US6232329B1/en not_active Expired - Fee Related
-
2006
- 2006-09-27 JP JP2006290515A patent/JP2007051154A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT721455E (pt) | Tetrahidropiridina-(ou 4-hidroxipiperidina) alquilazoles com uma actividade para os receptores sigma e/ou 5ht1a | |
NO971816L (no) | Farmasöytisk blanding for behandling av sykdommer forårsaket av IL-6 produksjon | |
PA8493701A1 (es) | Compuestos para tratar la obesidad | |
AU6226494A (en) | Spiroazacyclic derivatives as substance p antagonists | |
ATE412415T1 (de) | Inhibitoren der phosphodiesterase der zyklischen nucleotiden, mit einer benzodiazepinischen struktur, und deren verwendung in therapie | |
BRPI0410741A (pt) | composto e composições imunossupressores | |
NO20045589L (no) | Nye forbindelser | |
DE69802679D1 (de) | Verwendung von 1,2,4-triazolo(1,5-c)pyrimidine heterocyclischen analogen zur herstellung von arzneimitteln zur behandlung von zerebrovascularen störungen | |
LT2006017A (en) | 2-(quinoxalin-5-ylsulfonylamino)-benzamide compounds as cck2 modulators | |
ATE224718T1 (de) | Verwendung eines k-252a derivats zur behandlung von periphärer oder zentraler nervenerkrankungen und übermässiger cytokinbildung | |
CY1110417T1 (el) | Παραγωγα τρυπταμινης και αναλογες ενωσεις και φαρμακευτικες φαρμακοτεχνικες μορφες που περιεχουν αυτα | |
ATE152623T1 (de) | Verwendung von heterozyklischen derivaten zur herstellung von arzneimitteln | |
ATE210984T1 (de) | Verwendung von serotonin- und dopaminrezeptorblockern zur behandlung von mentalen erkrankungen verursacht durch zerebrovaskuläre erkrankungen | |
BR9608245A (pt) | Derivados de piperazino como antagonistas de neurocinina | |
ATE40369T1 (de) | Purinderivate. | |
ATE334680T1 (de) | 4-aminopiperidin-derivate, verfahren zur herstellung und ihre verwendung als arzneimittel | |
BR0210222A (pt) | Derivado de benzoxazepina, composição farmacêutica, uso de um derivado de benzoxazepina, e, método para tratar uma doença neurológica ou distúrbio psiquiátrico | |
DK1000067T3 (da) | Thiazolobenzoheterocycliske forbindelser, deres fremstilling og lægemidler indeholdende forbindelserne | |
ATE373658T1 (de) | Pyrazoloisoquinolinenderivaten zur inhibierung von nfkappab-induzierende kinase | |
RS20050393A (en) | Improved process for the preparation of 1,3-substituted indenes | |
AR024853A1 (es) | Pirrolocarbazoles e isoindolinas fusionados sustituidos ciclicos, composiciones farmaceuticas y usos de dichos compuestos para la fabricacion demedicamentos para tratar enfermedades que requieren la regulacion de proteina quinasa | |
MX9101926A (es) | Tetrahidropiridinas e hidroxipiperidinas substituidas como agentes del sistema nervioso central. | |
UA26393A (uk) | 3-циклоалкілпропаhамід, що проявляє протизапальhу і імуhодепресивhу активhість, спосіб його одержаhhя, ціаhамід і фармацевтичhа композиція |