PT71044A - A process for preparing mercaptoacyldipeptides - Google Patents

A process for preparing mercaptoacyldipeptides

Info

Publication number
PT71044A
PT71044A PT71044A PT7104480A PT71044A PT 71044 A PT71044 A PT 71044A PT 71044 A PT71044 A PT 71044A PT 7104480 A PT7104480 A PT 7104480A PT 71044 A PT71044 A PT 71044A
Authority
PT
Portugal
Prior art keywords
mercaptoacyldipeptides
preparing
preparing mercaptoacyldipeptides
Prior art date
Application number
PT71044A
Other languages
English (en)
Inventor
Miguel A Ondetti
Josip Pluscec
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of PT71044A publication Critical patent/PT71044A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052Val-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PT71044A 1979-04-02 1980-04-01 A process for preparing mercaptoacyldipeptides PT71044A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2570179A 1979-04-02 1979-04-02

Publications (1)

Publication Number Publication Date
PT71044A true PT71044A (en) 1980-05-01

Family

ID=21827594

Family Applications (1)

Application Number Title Priority Date Filing Date
PT71044A PT71044A (en) 1979-04-02 1980-04-01 A process for preparing mercaptoacyldipeptides

Country Status (22)

Country Link
JP (1) JPS55133345A (pt)
AT (1) AT373577B (pt)
AU (1) AU537592B2 (pt)
BE (1) BE882601A (pt)
CH (1) CH645092A5 (pt)
DE (1) DE3012140A1 (pt)
DK (1) DK140480A (pt)
ES (1) ES490166A0 (pt)
FR (1) FR2453135A1 (pt)
GB (1) GB2045771B (pt)
GR (1) GR67752B (pt)
HU (1) HU181087B (pt)
IE (1) IE49653B1 (pt)
IT (1) IT1147332B (pt)
LU (1) LU82316A1 (pt)
NL (1) NL8001675A (pt)
NO (1) NO150360C (pt)
NZ (1) NZ193142A (pt)
PH (1) PH22024A (pt)
PT (1) PT71044A (pt)
SE (1) SE8002512L (pt)
ZA (1) ZA801527B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5692848A (en) * 1979-12-27 1981-07-27 Dainippon Pharmaceut Co Ltd Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine
JPS56139455A (en) 1980-04-02 1981-10-30 Santen Pharmaceut Co Ltd Sulfur-containing acylaminoacid
US4336950A (en) * 1980-09-08 1982-06-29 John Zepkowski Sled
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
JPS57142967A (en) * 1981-02-27 1982-09-03 Dainippon Pharmaceut Co Ltd N-(acylthioalkanoyloxy)succinimide and its use
US4512979A (en) * 1981-03-23 1985-04-23 Merck & Co., Inc. Dipeptides containing thialysine and related amino acids as antihypertensives
US4382081A (en) * 1981-06-12 1983-05-03 E. R. Squibb & Sons, Inc. Inhibitors of mammalian collagenase
IT1195287B (it) * 1981-11-05 1988-10-12 Ausonia Farma Srl Derivato tiazolico,procedimento per la sua preparazione e relative composizioni farmaceutiche
US4434151A (en) * 1982-11-08 1984-02-28 Medi-Physics, Inc. Bifunctional chelating agents
DE3243369A1 (de) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen Bis-(benzoylthio)-carbonsaeuren, ihre herstellung und verwendung zur herstellung von wirkstoffen
US4642355A (en) * 1984-02-24 1987-02-10 Otsuka Pharmaceutical Factory, Inc. Proline derivatives
US4560506A (en) * 1984-05-25 1985-12-24 E. R. Squibb & Sons, Inc. Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides
DE3432307A1 (de) * 1984-09-03 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3436569A1 (de) * 1984-10-05 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
US4894437A (en) * 1985-11-15 1990-01-16 The Upjohn Company Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
EP0245361A1 (en) * 1985-11-15 1987-11-19 The Upjohn Company Novel renin inhibiting polypeptide analogs containing s-aryl-d- or l- or dl-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
JPH0662671B2 (ja) * 1986-01-17 1994-08-17 株式会社大塚製薬工場 プロリン誘導体
DE69130605T2 (de) * 1991-02-27 1999-05-20 Lacer Sa Antihypertensive N-(alpha-substituiertes Pyridyl)-carbonyldipeptide
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
GB9310075D0 (en) * 1993-05-17 1993-06-30 Fujisawa Pharmaceutical Co New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
US7390789B2 (en) * 2005-09-13 2008-06-24 William H Simmons Thio-containing inhibitors of aminopeptidase P, and compositions thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS559058A (en) * 1978-07-06 1980-01-22 Dainippon Pharmaceut Co Ltd 1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative

Also Published As

Publication number Publication date
IE49653B1 (en) 1985-11-13
NO800931L (no) 1980-10-03
IT8021110A0 (it) 1980-04-01
GR67752B (pt) 1981-09-18
GB2045771A (en) 1980-11-05
AU5638080A (en) 1980-10-09
NO150360C (no) 1984-10-03
DK140480A (da) 1980-10-03
PH22024A (en) 1988-05-13
IE800638L (en) 1980-10-02
GB2045771B (en) 1983-01-26
ES8104200A1 (es) 1981-04-01
LU82316A1 (fr) 1980-12-16
ZA801527B (en) 1981-03-25
JPS55133345A (en) 1980-10-17
ATA179480A (de) 1983-06-15
CH645092A5 (de) 1984-09-14
AT373577B (de) 1984-02-10
BE882601A (fr) 1980-10-02
NL8001675A (nl) 1980-10-06
AU537592B2 (en) 1984-07-05
ES490166A0 (es) 1981-04-01
DE3012140A1 (de) 1980-10-23
FR2453135A1 (fr) 1980-10-31
HU181087B (en) 1983-05-30
SE8002512L (sv) 1980-10-03
NZ193142A (en) 1984-08-24
FR2453135B1 (pt) 1983-06-17
NO150360B (no) 1984-06-25
IT1147332B (it) 1986-11-19

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960831

NF3A Restitutio in integrum

Effective date: 19970502

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980831