JPS57142967A - N-(acylthioalkanoyloxy)succinimide and its use - Google Patents
N-(acylthioalkanoyloxy)succinimide and its useInfo
- Publication number
- JPS57142967A JPS57142967A JP56028981A JP2898181A JPS57142967A JP S57142967 A JPS57142967 A JP S57142967A JP 56028981 A JP56028981 A JP 56028981A JP 2898181 A JP2898181 A JP 2898181A JP S57142967 A JPS57142967 A JP S57142967A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- succinimide
- 1mol
- organic solvent
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:The N-(acylthioalkanoyloxy)succinimide of formula (X is lower alkylene; Y is lower alkyl or phenyl).
EXAMPLE: N-(2-Acetylthioacetyloxy)succinimide.
USE: Reagent for introducing a thiol group into the amino compound such as protein (e.g. enzyme, antibody, glycoprotein, lipoprotein, albumin, etc.), lower molecular weight compound (e.g. medicine, vitamine, hormone, etc.), artificial polymeric compound (e.g. partially hydrolyzed nylon, bacterial cell wall, amino group- introduced cellulose, etc.), etc.
PROCESS: The compound of formula is prepared by adding an anhydrous organic solvent containing 1mol of dicyclohexylcarbodiimide to an anhydrous organic solvent containing 1mol of N-hydroxysuccinimide and 1mol of acylthioalkanoic acid under stirring and cooling, stirring the mixture at room temperature, and filtering the product.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56028981A JPS57142967A (en) | 1981-02-27 | 1981-02-27 | N-(acylthioalkanoyloxy)succinimide and its use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56028981A JPS57142967A (en) | 1981-02-27 | 1981-02-27 | N-(acylthioalkanoyloxy)succinimide and its use |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57142967A true JPS57142967A (en) | 1982-09-03 |
Family
ID=12263585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56028981A Pending JPS57142967A (en) | 1981-02-27 | 1981-02-27 | N-(acylthioalkanoyloxy)succinimide and its use |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57142967A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007000178A (en) * | 2005-06-21 | 2007-01-11 | Okamura Corp | Index attaching structure of shelf |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1034573A (en) * | 1974-08-01 | 1978-07-11 | Peter J.L. Daniels | Preparation of 1-n-substituted 4,6-di-(aminoglycosyl)-1,3-diaminocyclitols |
DE3012140A1 (en) * | 1979-04-02 | 1980-10-23 | Squibb & Sons Inc | MERCAPTOACYLPEPTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS ACE INHIBITORS AND IN THE TREATMENT OF HIGH PRESSURE |
-
1981
- 1981-02-27 JP JP56028981A patent/JPS57142967A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1034573A (en) * | 1974-08-01 | 1978-07-11 | Peter J.L. Daniels | Preparation of 1-n-substituted 4,6-di-(aminoglycosyl)-1,3-diaminocyclitols |
DE3012140A1 (en) * | 1979-04-02 | 1980-10-23 | Squibb & Sons Inc | MERCAPTOACYLPEPTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS ACE INHIBITORS AND IN THE TREATMENT OF HIGH PRESSURE |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007000178A (en) * | 2005-06-21 | 2007-01-11 | Okamura Corp | Index attaching structure of shelf |
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