JPS57142967A - N-(acylthioalkanoyloxy)succinimide and its use - Google Patents

N-(acylthioalkanoyloxy)succinimide and its use

Info

Publication number
JPS57142967A
JPS57142967A JP56028981A JP2898181A JPS57142967A JP S57142967 A JPS57142967 A JP S57142967A JP 56028981 A JP56028981 A JP 56028981A JP 2898181 A JP2898181 A JP 2898181A JP S57142967 A JPS57142967 A JP S57142967A
Authority
JP
Japan
Prior art keywords
compound
succinimide
1mol
organic solvent
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56028981A
Other languages
Japanese (ja)
Inventor
Shigeru Kurooka
Akira Kagemoto
Noriyuki Sunahara
Chikae Yokogawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dainippon Pharmaceutical Co Ltd
Original Assignee
Dainippon Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co Ltd filed Critical Dainippon Pharmaceutical Co Ltd
Priority to JP56028981A priority Critical patent/JPS57142967A/en
Publication of JPS57142967A publication Critical patent/JPS57142967A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:The N-(acylthioalkanoyloxy)succinimide of formula (X is lower alkylene; Y is lower alkyl or phenyl).
EXAMPLE: N-(2-Acetylthioacetyloxy)succinimide.
USE: Reagent for introducing a thiol group into the amino compound such as protein (e.g. enzyme, antibody, glycoprotein, lipoprotein, albumin, etc.), lower molecular weight compound (e.g. medicine, vitamine, hormone, etc.), artificial polymeric compound (e.g. partially hydrolyzed nylon, bacterial cell wall, amino group- introduced cellulose, etc.), etc.
PROCESS: The compound of formula is prepared by adding an anhydrous organic solvent containing 1mol of dicyclohexylcarbodiimide to an anhydrous organic solvent containing 1mol of N-hydroxysuccinimide and 1mol of acylthioalkanoic acid under stirring and cooling, stirring the mixture at room temperature, and filtering the product.
COPYRIGHT: (C)1982,JPO&Japio
JP56028981A 1981-02-27 1981-02-27 N-(acylthioalkanoyloxy)succinimide and its use Pending JPS57142967A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56028981A JPS57142967A (en) 1981-02-27 1981-02-27 N-(acylthioalkanoyloxy)succinimide and its use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56028981A JPS57142967A (en) 1981-02-27 1981-02-27 N-(acylthioalkanoyloxy)succinimide and its use

Publications (1)

Publication Number Publication Date
JPS57142967A true JPS57142967A (en) 1982-09-03

Family

ID=12263585

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56028981A Pending JPS57142967A (en) 1981-02-27 1981-02-27 N-(acylthioalkanoyloxy)succinimide and its use

Country Status (1)

Country Link
JP (1) JPS57142967A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007000178A (en) * 2005-06-21 2007-01-11 Okamura Corp Index attaching structure of shelf

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1034573A (en) * 1974-08-01 1978-07-11 Peter J.L. Daniels Preparation of 1-n-substituted 4,6-di-(aminoglycosyl)-1,3-diaminocyclitols
DE3012140A1 (en) * 1979-04-02 1980-10-23 Squibb & Sons Inc MERCAPTOACYLPEPTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS ACE INHIBITORS AND IN THE TREATMENT OF HIGH PRESSURE

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1034573A (en) * 1974-08-01 1978-07-11 Peter J.L. Daniels Preparation of 1-n-substituted 4,6-di-(aminoglycosyl)-1,3-diaminocyclitols
DE3012140A1 (en) * 1979-04-02 1980-10-23 Squibb & Sons Inc MERCAPTOACYLPEPTIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS ACE INHIBITORS AND IN THE TREATMENT OF HIGH PRESSURE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007000178A (en) * 2005-06-21 2007-01-11 Okamura Corp Index attaching structure of shelf

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