JPS5692848A - Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine - Google Patents
Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanineInfo
- Publication number
- JPS5692848A JPS5692848A JP17243579A JP17243579A JPS5692848A JP S5692848 A JPS5692848 A JP S5692848A JP 17243579 A JP17243579 A JP 17243579A JP 17243579 A JP17243579 A JP 17243579A JP S5692848 A JPS5692848 A JP S5692848A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- methylpropanoyl
- alaknoylthio
- prolylphenylalanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:The titled compound of formula I (R1 is lower alkyl). EXAMPLE:1-(D-3-Acethylthio-2-methylpropanoyl)-L-prolyl-L-phenylalanine. USE:A hypotensive agent having a mild action with a long duration based on the inhibitory action on an angiotensin I converting enzyme. PROCESS:A compound of formula II or a reactive derivative at the carboxyl group thereof is reacted with a compound of formula III (R2 is H or t-butyl). The group R2, if t-butyl, is then removed, and the reaction product is separated into individual isomers if desired to give the compound of formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17243579A JPS5692848A (en) | 1979-12-27 | 1979-12-27 | Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17243579A JPS5692848A (en) | 1979-12-27 | 1979-12-27 | Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5692848A true JPS5692848A (en) | 1981-07-27 |
JPS6318599B2 JPS6318599B2 (en) | 1988-04-19 |
Family
ID=15941920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP17243579A Granted JPS5692848A (en) | 1979-12-27 | 1979-12-27 | Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5692848A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55133345A (en) * | 1979-04-02 | 1980-10-17 | Squibb & Sons Inc | Mercaptoacyldipeptides |
-
1979
- 1979-12-27 JP JP17243579A patent/JPS5692848A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55133345A (en) * | 1979-04-02 | 1980-10-17 | Squibb & Sons Inc | Mercaptoacyldipeptides |
Also Published As
Publication number | Publication date |
---|---|
JPS6318599B2 (en) | 1988-04-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UA6322A1 (en) | StarWriterPROCESS FOR PRAPARATION 3,6-DICHLOROPICOLINIC ACID | |
AU545556B2 (en) | Use of dihydro-1h-pyrollizine 3,5 dione as a cognition activator | |
JPS53143684A (en) | Polymerization of olefin | |
JPS5692848A (en) | Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine | |
ES8204425A1 (en) | Process for the preparation of cimetidine. | |
JPS5697266A (en) | Proline derivative and its preparation | |
JPS52114092A (en) | Preparation of l-arginine by fermentation process | |
EP0295090A3 (en) | Chemical process | |
JPS5424856A (en) | 1-(3 or 4-methyl-3-cyclohexenyl)-2-methyl-1-penten-3-ol | |
JPS5531086A (en) | Prepartion of 5,6-epoxy-1,2,6-trimethyl-tricyclo 5.3.2.02,7 dodecane | |
JPS5545649A (en) | Novel nootkatone and vetivone derivative, their novel intermediate, their preparation and use | |
JPS51151393A (en) | Process for preparing nojirimycin b | |
JPS55108883A (en) | Ethyl-(gamma-acetamino-gamma-ethoxycarbonyl-gamma-cyanopropyl- methyl) phosphinate and its preparation | |
JPS56118053A (en) | Carbodiimide derivative, insecticidal and acaricidal agent | |
ES8403102A1 (en) | Fluorophenoxybenzyl esters, their preparation and use as pesticides. | |
JPS5427582A (en) | Preparation of dinucleoside triphosphate | |
JPS5334750A (en) | Preparation of cyclopentadeca-4-yne-one | |
JPS5463087A (en) | 8-fluoro-1-methylcarbostyryl and fungicide for rice plant containing the same | |
JPS5772996A (en) | Novel oligomannoside and its preparation | |
JPS5231059A (en) | Preparation of oxybenzoylbenzoic acids | |
JPS57169464A (en) | Tetrahydroisoquinoline derivative and its preparation | |
JPS5517361A (en) | 7-methylene-cis-decalin-2-one | |
JPS5346964A (en) | Preparation of s-phthalimidemethyl-0,0-dialkyldithio or thiophosphate | |
JPS5553264A (en) | 3-(n-substituted carbamoylthio)-2(s)-methylpropionic acid | |
JPS55139376A (en) | Pyridazine derivative |