PT3006049T - Composição para extrusão por fusão a quente e método para produzir um produto extrudido por fusão a quente - Google Patents
Composição para extrusão por fusão a quente e método para produzir um produto extrudido por fusão a quenteInfo
- Publication number
- PT3006049T PT3006049T PT148069453T PT14806945T PT3006049T PT 3006049 T PT3006049 T PT 3006049T PT 148069453 T PT148069453 T PT 148069453T PT 14806945 T PT14806945 T PT 14806945T PT 3006049 T PT3006049 T PT 3006049T
- Authority
- PT
- Portugal
- Prior art keywords
- hot melt
- producing
- composition
- extruded product
- melt extrusion
- Prior art date
Links
- 235000012438 extruded product Nutrition 0.000 title 1
- 238000009474 hot melt extrusion Methods 0.000 title 1
- 239000012943 hotmelt Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/193—Mixed ethers, i.e. ethers with two or more different etherifying groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B13/00—Preparation of cellulose ether-esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/20—Compounding polymers with additives, e.g. colouring
- C08J3/201—Pre-melted polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/32—Cellulose ether-esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2301/00—Characterised by the use of cellulose, modified cellulose or cellulose derivatives
- C08J2301/08—Cellulose derivatives
- C08J2301/32—Cellulose ether-esters
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013116836 | 2013-06-03 | ||
| JP2013246178 | 2013-11-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3006049T true PT3006049T (pt) | 2018-03-20 |
Family
ID=50842156
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT148069453T PT3006049T (pt) | 2013-06-03 | 2014-06-03 | Composição para extrusão por fusão a quente e método para produzir um produto extrudido por fusão a quente |
| PT141708636T PT2810660T (pt) | 2013-06-03 | 2014-06-03 | Composição para extrusão termofusível e método para produzir produto de extrusão termofusível com o uso da mesma |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT141708636T PT2810660T (pt) | 2013-06-03 | 2014-06-03 | Composição para extrusão termofusível e método para produzir produto de extrusão termofusível com o uso da mesma |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10646573B2 (https=) |
| EP (2) | EP3006049B1 (https=) |
| JP (2) | JP6126555B2 (https=) |
| KR (2) | KR102228157B1 (https=) |
| CN (2) | CN104208713B (https=) |
| IN (1) | IN2014DE01467A (https=) |
| PT (2) | PT3006049T (https=) |
| WO (1) | WO2014196519A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3006049T (pt) | 2013-06-03 | 2018-03-20 | Shinetsu Chemical Co | Composição para extrusão por fusão a quente e método para produzir um produto extrudido por fusão a quente |
| JP6203702B2 (ja) * | 2014-11-18 | 2017-09-27 | 信越化学工業株式会社 | ヒプロメロース酢酸エステルコハク酸エステルを用いたスプレードライ用溶液及び固体分散体の製造方法 |
| CA2970717A1 (en) | 2014-12-18 | 2016-06-23 | Merck Sharp & Dohme Corp. | (s)-n-(3-(6-isopropoxypyridin-3-yl)-1h-indazol-5-yl)-1-(2-(4-(4-(1-methyl-1h-1,2,4-triazol-3-yl)phenyl)-3,6-dihydropyridin-1(2h)-yl)-2-oxoethyl)-3- (methylthio)pyrrolidine-3-carboxamide compositions for pharmaceutical preparations |
| KR20180008524A (ko) * | 2015-05-15 | 2018-01-24 | 다우 글로벌 테크놀로지스 엘엘씨 | 초고분자량 및 저점도의 에스테르화된 셀룰로오스 에테르의 제조 방법 |
| BR112017023845A2 (pt) * | 2015-05-15 | 2018-07-31 | Dow Global Technologies Llc | processo de preparação de um éter de celulose esterificado de peso molecular elevado |
| BR112018001792A2 (pt) | 2015-07-28 | 2018-09-11 | Dow Global Technologies Llc | processo para produzir dispersão de éter de celulose esterificado |
| WO2018170083A1 (en) | 2017-03-17 | 2018-09-20 | Dow Global Technologies Llc | Process for recovering an esterified cellulose ether from a reaction product mixture |
| JP2020511572A (ja) | 2017-03-17 | 2020-04-16 | ダウ グローバル テクノロジーズ エルエルシー | 反応生成物混合物からのエステル化セルロースエーテルの回収方法 |
| CN110366566B (zh) | 2017-03-17 | 2021-08-13 | 陶氏环球技术有限责任公司 | 用于从反应产物混合物中回收酯化纤维素醚的方法 |
| US20180282527A1 (en) * | 2017-03-30 | 2018-10-04 | Shin-Etsu Chemical Co., Ltd. | Injection molding composition containing hypromellose acetate succinate and method for producing same |
| CN109078186B (zh) * | 2017-06-14 | 2021-09-03 | 江苏恒瑞医药股份有限公司 | 一种胃漂浮组合物及其制备方法 |
| TR201722852A2 (tr) * | 2017-12-29 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Mesalazi̇ni̇n oral farmasöti̇k kompozi̇syonlari |
| WO2020131801A1 (en) | 2018-12-18 | 2020-06-25 | DDP Specialty Electronic Materials US, Inc. | A sustained release composition comprising a hydroxypropyl methylcellulose acetate succinate |
| JP7050714B2 (ja) | 2019-04-04 | 2022-04-08 | 信越化学工業株式会社 | 腸溶性コーティング用組成物及び固形製剤の製造方法 |
| JP7273691B2 (ja) | 2019-11-01 | 2023-05-15 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースフタレートの製造方法 |
| JP7252882B2 (ja) * | 2019-11-01 | 2023-04-05 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースアセテートサクシネートの製造方法 |
| WO2021118915A1 (en) | 2019-12-09 | 2021-06-17 | Nutrition & Biosciences Usa 1, Llc | Hydroxypropyl alkyl cellulose acetate succinate heteropolymers |
| WO2022034232A1 (en) | 2020-08-13 | 2022-02-17 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant high-strength formulation containing posaconazole |
| JP7399060B2 (ja) * | 2020-10-01 | 2023-12-15 | 信越化学工業株式会社 | ヒドロキシプロピルメチルセルロースアセテートサクシネートの製造方法 |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
| CN115581678B (zh) * | 2022-11-04 | 2023-09-12 | 北京鑫开元医药科技有限公司 | 一种瑞派替尼片组合物及其制备方法 |
| CN115651085B (zh) * | 2022-11-14 | 2023-11-17 | 乳源东阳光药业有限公司 | 一种醋酸羟丙甲纤维素琥珀酸酯的纯化方法 |
| KR102945795B1 (ko) * | 2023-10-16 | 2026-03-30 | 강원대학교산학협력단 | 서방형 약물전달체를 유효성분으로 포함하는 염증성 장질환의 예방, 개선 또는 치료용 조성물 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3852421A (en) | 1970-03-23 | 1974-12-03 | Shinetsu Chemical Co | Excipient and shaped medicaments prepared therewith |
| US4226981A (en) * | 1977-09-28 | 1980-10-07 | Shin-Etsu Chemical Co., Ltd. | Ether-ester derivatives of cellulose and their applications |
| JPS5951562B2 (ja) | 1977-10-25 | 1984-12-14 | 信越化学工業株式会社 | セルロ−スエ−テルの酸性サクシニルおよび脂肪族モノアシル混成エステルの製造方法 |
| US4266981A (en) | 1978-03-08 | 1981-05-12 | Purdue Research Corporation | Process for recovering and utilizing cellulose using sulfuric acid |
| DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
| AR038375A1 (es) | 2002-02-01 | 2005-01-12 | Pfizer Prod Inc | Composiciones farmaceuticas de inhibidores de la proteina de transferencia de esteres de colesterilo |
| WO2003077827A1 (en) | 2002-03-19 | 2003-09-25 | Nippon Shinyaku Co., Ltd. | Process for producing drug solid dispersion |
| KR100454394B1 (ko) | 2002-03-27 | 2004-10-26 | 이원희 | 맥파검출장치 |
| JP4344914B2 (ja) | 2003-02-28 | 2009-10-14 | 信越化学工業株式会社 | アルカリ溶解性カルボン酸エステル系セルロース誘導体及び該誘導体からなるフィルム |
| CA2568007A1 (en) * | 2004-05-28 | 2005-12-08 | Pfizer Products Inc. | Pharmaceutical compositions with enhanced performance |
| EP1923051A4 (en) * | 2005-09-06 | 2012-12-19 | Astellas Pharma Inc | MICROPARTICLES OF A HEAVY-DUTY SUBSTANCE WITH ENTERIAN BASE MATERIAL ADSORBED ON THE SUBSTANCE SURFACE |
| JP5576922B2 (ja) * | 2006-04-20 | 2014-08-20 | 信越化学工業株式会社 | 腸溶性固体分散体を含んでなる固形製剤 |
| JP5070618B2 (ja) * | 2006-06-16 | 2012-11-14 | トーアエイヨー株式会社 | 腸溶性顆粒剤及びその製造方法 |
| JP5052051B2 (ja) * | 2006-06-16 | 2012-10-17 | トーアエイヨー株式会社 | 腸溶性顆粒剤及びその製造方法 |
| CN101686994B (zh) * | 2006-10-20 | 2013-05-01 | 陶氏环球技术公司 | 水溶性纤维素衍生物制备用于预防或治疗代谢综合征的药物等的用途 |
| EP2278957A2 (en) | 2008-04-15 | 2011-02-02 | Schering Corporation | Oral pharmaceutical compositions in a solid dispersion comprising preferably posaconazole and hpmcas |
| CN102065842A (zh) * | 2008-04-15 | 2011-05-18 | 先灵公司 | 优选含有泊沙康唑和hpmcas的固体分散体形式的口服药物组合物 |
| EP3451035B1 (en) | 2010-02-03 | 2019-11-27 | Tyco Electronics Nederland B.V. | Enclosure assembly for a connector, strain relief element, and method |
| JP5792807B2 (ja) | 2010-06-14 | 2015-10-14 | ダウ グローバル テクノロジーズ エルエルシー | アセテートおよびサクシネートの置換が向上されたヒドロキシプロピルメチルセルロースアセテートサクシネート |
| US8409560B2 (en) * | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| US8591944B2 (en) | 2011-03-08 | 2013-11-26 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| US20120251588A1 (en) * | 2011-03-30 | 2012-10-04 | Miyuki Fukasawa | Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation |
| JP2013116836A (ja) | 2011-12-02 | 2013-06-13 | Sharp Corp | シリコン端材の再利用方法並びに原料シリコン、多結晶シリコン材料及び多結晶シリコン太陽電池の製造方法 |
| DE102012010430A1 (de) | 2012-05-29 | 2013-12-05 | Krohne Ag | Durchflussmessgerät |
| MX2015002430A (es) | 2012-08-24 | 2015-06-22 | Dow Global Technologies Llc | Acetato-succinatos de hidroxialquilmetilcelulosa. |
| PT3006049T (pt) | 2013-06-03 | 2018-03-20 | Shinetsu Chemical Co | Composição para extrusão por fusão a quente e método para produzir um produto extrudido por fusão a quente |
-
2014
- 2014-06-03 PT PT148069453T patent/PT3006049T/pt unknown
- 2014-06-03 EP EP14806945.3A patent/EP3006049B1/en active Active
- 2014-06-03 CN CN201410242677.6A patent/CN104208713B/zh active Active
- 2014-06-03 KR KR1020157034116A patent/KR102228157B1/ko active Active
- 2014-06-03 CN CN201480030211.8A patent/CN105283203B/zh active Active
- 2014-06-03 WO PCT/JP2014/064711 patent/WO2014196519A1/ja not_active Ceased
- 2014-06-03 JP JP2014114900A patent/JP6126555B2/ja active Active
- 2014-06-03 US US14/892,421 patent/US10646573B2/en active Active
- 2014-06-03 US US14/294,258 patent/US10016508B2/en active Active
- 2014-06-03 IN IN1467DE2014 patent/IN2014DE01467A/en unknown
- 2014-06-03 KR KR1020140067370A patent/KR101918327B1/ko active Active
- 2014-06-03 PT PT141708636T patent/PT2810660T/pt unknown
- 2014-06-03 EP EP14170863.6A patent/EP2810660B1/en active Active
- 2014-06-03 JP JP2015521450A patent/JP6007322B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014196519A1 (ja) | 2014-12-11 |
| JP2015127316A (ja) | 2015-07-09 |
| KR20140142173A (ko) | 2014-12-11 |
| US20160095928A1 (en) | 2016-04-07 |
| IN2014DE01467A (https=) | 2015-07-24 |
| CN104208713A (zh) | 2014-12-17 |
| CN105283203B (zh) | 2018-12-28 |
| KR20160015234A (ko) | 2016-02-12 |
| EP3006049A4 (en) | 2017-02-22 |
| US10646573B2 (en) | 2020-05-12 |
| EP3006049B1 (en) | 2018-02-28 |
| CN104208713B (zh) | 2018-04-27 |
| EP3006049A1 (en) | 2016-04-13 |
| US10016508B2 (en) | 2018-07-10 |
| JP6126555B2 (ja) | 2017-05-10 |
| US20140357681A1 (en) | 2014-12-04 |
| CN105283203A (zh) | 2016-01-27 |
| EP2810660A1 (en) | 2014-12-10 |
| JPWO2014196519A1 (ja) | 2017-02-23 |
| EP2810660B1 (en) | 2017-07-26 |
| PT2810660T (pt) | 2017-08-16 |
| KR102228157B1 (ko) | 2021-03-17 |
| KR101918327B1 (ko) | 2018-11-13 |
| JP6007322B2 (ja) | 2016-10-12 |
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