PT2948461T - Compostos e métodos para o tratamento de infeções bacterianas - Google Patents

Compostos e métodos para o tratamento de infeções bacterianas

Info

Publication number
PT2948461T
PT2948461T PT147026421T PT14702642T PT2948461T PT 2948461 T PT2948461 T PT 2948461T PT 147026421 T PT147026421 T PT 147026421T PT 14702642 T PT14702642 T PT 14702642T PT 2948461 T PT2948461 T PT 2948461T
Authority
PT
Portugal
Prior art keywords
compounds
methods
bacterial infections
treating bacterial
treating
Prior art date
Application number
PT147026421T
Other languages
English (en)
Original Assignee
Entasis Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entasis Therapeutics Ltd filed Critical Entasis Therapeutics Ltd
Publication of PT2948461T publication Critical patent/PT2948461T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT147026421T 2013-01-23 2014-01-22 Compostos e métodos para o tratamento de infeções bacterianas PT2948461T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361755537P 2013-01-23 2013-01-23
US201361859910P 2013-07-30 2013-07-30

Publications (1)

Publication Number Publication Date
PT2948461T true PT2948461T (pt) 2020-03-31

Family

ID=50033593

Family Applications (1)

Application Number Title Priority Date Filing Date
PT147026421T PT2948461T (pt) 2013-01-23 2014-01-22 Compostos e métodos para o tratamento de infeções bacterianas

Country Status (31)

Country Link
US (4) US8889671B2 (pt)
EP (1) EP2948461B1 (pt)
JP (1) JP6285960B2 (pt)
KR (1) KR102149567B1 (pt)
CN (1) CN105229012B (pt)
AR (1) AR094565A1 (pt)
AU (1) AU2014208965B2 (pt)
BR (1) BR112015017519B1 (pt)
CA (1) CA2897887C (pt)
CY (1) CY1122805T1 (pt)
DK (1) DK2948461T3 (pt)
EA (1) EA026901B1 (pt)
ES (1) ES2780824T3 (pt)
HK (1) HK1218293A1 (pt)
HR (1) HRP20200401T1 (pt)
HU (1) HUE048990T2 (pt)
IL (1) IL239860A0 (pt)
LT (1) LT2948461T (pt)
ME (1) ME03676B (pt)
MX (1) MX360650B (pt)
MY (1) MY192765A (pt)
NZ (1) NZ710091A (pt)
PH (1) PH12015501588B1 (pt)
PL (1) PL2948461T3 (pt)
PT (1) PT2948461T (pt)
RS (1) RS60078B1 (pt)
SG (1) SG11201505462YA (pt)
SI (1) SI2948461T1 (pt)
TW (1) TWI603973B (pt)
UY (1) UY35274A (pt)
WO (1) WO2014114929A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9040528B2 (en) * 2008-10-14 2015-05-26 Astrazeneca Ab Chemical compounds 542
US8889671B2 (en) * 2013-01-23 2014-11-18 Astrazeneca Ab Compounds and methods for treating bacterial infections
SG10201906842WA (en) * 2014-05-29 2019-08-27 Entasis Therapeutics Ltd Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections
US10660933B2 (en) * 2015-10-29 2020-05-26 University Of Maryland, College Park Compositions and methods for inhibition of bacterial infections in human endocervix
CN106632298B (zh) * 2015-11-03 2021-06-01 上海科胜药物研发有限公司 一种泰地唑胺的制备方法及其中间体
BR112019024950A2 (pt) 2017-06-01 2020-06-23 Bristol-Myers Squibb Company Compostos contendo nitrogênio substituído
WO2018233670A1 (zh) * 2017-06-22 2018-12-27 中国科学院上海药物研究所 苯并异噁唑螺嘧啶三酮类化合物及制备方法和用途
CN109111465B (zh) * 2017-06-22 2021-01-12 中国科学院上海药物研究所 噻唑烷酮螺嘧啶三酮类化合物及制备方法和用途
CN109111466B (zh) * 2017-06-22 2022-08-02 中国科学院上海药物研究所 苯并异噁唑螺嘧啶三酮类化合物及制备方法和用途
CN108060207B (zh) * 2017-12-29 2021-10-15 河南科技大学 一种基于微量天然化合物的最小杀菌浓度测定方法
US11905286B2 (en) 2018-08-09 2024-02-20 Antabio Sas Diazabicyclooctanones as inhibitors of serine beta-lactamases
CN111559985A (zh) * 2020-05-13 2020-08-21 河南科技大学第一附属医院 具有杀菌作用的噁唑酮类化合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759570B2 (ja) 1986-05-06 1995-06-28 三井東圧化学株式会社 2−オキサゾリジノン類の製造方法
US7208490B2 (en) 2002-10-07 2007-04-24 Pharmacia & Upjohn Company Llc Tricyclic tetrahydroquinoline antibacterial agents
EP1664052B1 (en) 2003-08-15 2009-02-18 AstraZeneca AB Fused heterocycles as inhibitors of glutamate racemase (muri)
US7361689B2 (en) 2003-12-31 2008-04-22 Schering-Plough Animal Health Corporation Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
JP2008543739A (ja) 2005-05-09 2008-12-04 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 抗菌剤
DOP2006000268A (es) 2005-12-22 2007-07-31 Pfizer Prod Inc Agentes antibacterianos
CL2007003332A1 (es) * 2006-11-24 2008-06-20 Actelion Pharmaceuticals Ltd Compuestos derivados de heterociclos condensados; compuestos intermediarios; composicion farmaceutica; y uso en la prevencion o tratamiento de infecciones bacterianas.
JP2010531868A (ja) 2007-07-02 2010-09-30 アストラゼネカ アクチボラグ 3−スピロピリミジントリオン−キノリン誘導体と抗菌剤としてのその使用
US9040528B2 (en) 2008-10-14 2015-05-26 Astrazeneca Ab Chemical compounds 542
MX2011003598A (es) 2008-10-14 2011-04-27 Astrazeneca Ab Compuestos heteroaromaticos espirociclicos, fusionados, para el tratamiento de infecciones bacterianas.
US8952149B2 (en) 2012-09-26 2015-02-10 Zoetis Llc Tricyclic tetrahydroquinoline antibacterial agents
US8889671B2 (en) * 2013-01-23 2014-11-18 Astrazeneca Ab Compounds and methods for treating bacterial infections

Also Published As

Publication number Publication date
BR112015017519B1 (pt) 2021-01-19
CA2897887A1 (en) 2014-07-31
HK1218293A1 (zh) 2017-02-10
BR112015017519A2 (pt) 2017-11-21
ME03676B (me) 2020-10-20
US9839641B2 (en) 2017-12-12
CN105229012A (zh) 2016-01-06
AR094565A1 (es) 2015-08-12
KR20150107875A (ko) 2015-09-23
HUE048990T2 (hu) 2020-09-28
AU2014208965B2 (en) 2017-07-27
ES2780824T3 (es) 2020-08-27
CY1122805T1 (el) 2021-05-05
US20140206677A1 (en) 2014-07-24
US20170128458A1 (en) 2017-05-11
HRP20200401T1 (hr) 2020-06-12
SI2948461T1 (sl) 2020-06-30
KR102149567B1 (ko) 2020-08-28
RS60078B1 (sr) 2020-05-29
PH12015501588A1 (en) 2015-10-05
AU2014208965A1 (en) 2015-07-30
EA026901B1 (ru) 2017-05-31
PL2948461T3 (pl) 2020-09-07
SG11201505462YA (en) 2015-08-28
US9540394B2 (en) 2017-01-10
MX2015009479A (es) 2016-03-04
DK2948461T3 (en) 2020-02-17
CA2897887C (en) 2021-09-07
US20160130281A1 (en) 2016-05-12
US20150203513A1 (en) 2015-07-23
EP2948461B1 (en) 2019-12-25
EA201591362A1 (ru) 2015-11-30
MX360650B (es) 2018-11-12
TWI603973B (zh) 2017-11-01
LT2948461T (lt) 2020-03-25
NZ710091A (en) 2019-08-30
US9187495B2 (en) 2015-11-17
WO2014114929A1 (en) 2014-07-31
UY35274A (es) 2014-07-31
TW201443063A (zh) 2014-11-16
JP2016506922A (ja) 2016-03-07
EP2948461A1 (en) 2015-12-02
IL239860A0 (en) 2015-08-31
JP6285960B2 (ja) 2018-02-28
PH12015501588B1 (en) 2015-10-05
MY192765A (en) 2022-09-07
US8889671B2 (en) 2014-11-18
CN105229012B (zh) 2017-07-18

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