HK1213268A1 - 用於治療細菌感染的甘露糖衍生物 - Google Patents
用於治療細菌感染的甘露糖衍生物Info
- Publication number
- HK1213268A1 HK1213268A1 HK16101243.5A HK16101243A HK1213268A1 HK 1213268 A1 HK1213268 A1 HK 1213268A1 HK 16101243 A HK16101243 A HK 16101243A HK 1213268 A1 HK1213268 A1 HK 1213268A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- bacterial infections
- treating bacterial
- mannose derivatives
- mannose
- derivatives
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 150000002703 mannose derivatives Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361777398P | 2013-03-12 | 2013-03-12 | |
| PCT/US2014/024411 WO2014165107A2 (en) | 2013-03-12 | 2014-03-12 | Mannose derivatives for treating bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1213268A1 true HK1213268A1 (zh) | 2016-06-30 |
Family
ID=50639929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16101243.5A HK1213268A1 (zh) | 2013-03-12 | 2016-02-03 | 用於治療細菌感染的甘露糖衍生物 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9890176B2 (zh) |
| EP (1) | EP2970353B1 (zh) |
| JP (1) | JP6373352B2 (zh) |
| KR (1) | KR102249702B1 (zh) |
| CN (1) | CN105164142B (zh) |
| AU (1) | AU2014248717B2 (zh) |
| CA (1) | CA2905019C (zh) |
| DK (1) | DK2970353T3 (zh) |
| ES (1) | ES2677115T3 (zh) |
| HK (1) | HK1213268A1 (zh) |
| IL (1) | IL241358B (zh) |
| MX (1) | MX2015012472A (zh) |
| PL (1) | PL2970353T3 (zh) |
| RU (1) | RU2678327C2 (zh) |
| WO (1) | WO2014165107A2 (zh) |
| ZA (1) | ZA201507241B (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6412506B2 (ja) | 2012-12-18 | 2018-10-24 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 細菌感染を処置するためのマンノース誘導体 |
| US20200002303A1 (en) * | 2016-03-11 | 2020-01-02 | Fimbrion Therapeutics, Inc. | C-glycoside compounds useful for treating disease |
| RU2018131440A (ru) * | 2016-03-23 | 2020-04-23 | Фимбрион Терапеутикс, Инк. | Антагонисты FimH, являющиеся производными маннозы, пригодные для лечения заболевания |
| IL279993B2 (en) | 2018-07-10 | 2024-01-01 | Glaxosmithkline Ip Dev Ltd | Mannoside-C compounds are useful for treating urinary tract infections |
| CN113461753B (zh) * | 2020-03-31 | 2023-05-23 | 郑计岳 | 2-炔基甘露糖衍生物及其应用 |
| CN115253144A (zh) * | 2022-08-09 | 2022-11-01 | 青岛嘉智生物技术有限公司 | 针对戊二醛类消毒剂的中和剂及其制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0619317A1 (en) | 1993-04-07 | 1994-10-12 | Centre National De La Recherche Scientifique | An expeditious synthesis of C-disaccharides using a temporary ketal connection |
| DE69433901T2 (de) * | 1993-11-18 | 2005-07-28 | Siga Technologies, Inc. | Verbindungen und pharmazeutische zusammensetzungen zur behandlung und prophylaxe bakterieller infektionen |
| AU6024998A (en) | 1997-01-15 | 1998-08-07 | Glycomed Incorporated | Aryl c-glycoside compounds and sulfated esters thereof |
| AUPQ872300A0 (en) | 2000-07-11 | 2000-08-03 | Praxis Pharmaceuticals Pty Ltd | Compounds and methods |
| EP1613261A4 (en) | 2003-04-09 | 2011-01-26 | Novo Nordisk As | INTRA-CELLULAR FORMATION OF PEPTIDE CONJUGATES |
| US20080171706A1 (en) | 2004-03-23 | 2008-07-17 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections |
| FR2876798A1 (fr) | 2004-10-14 | 2006-04-21 | Univ Clermont Auvergne | Diagnostic et traitement de la maladie de crohn |
| US20100197687A1 (en) | 2005-01-19 | 2010-08-05 | Benjamin Pelcman | Indoles Useful in the Treatment of Inflammation |
| CA2594773A1 (en) | 2005-01-19 | 2006-07-27 | Biolipox Ab | Indoles useful in the treatment of inflammation |
| US20080249091A1 (en) | 2005-01-19 | 2008-10-09 | Benjamin Pelcman | Indoles Useful in the Treatment of Inflammation |
| CN101142185A (zh) | 2005-01-19 | 2008-03-12 | 比奥里波克斯公司 | 用于炎症治疗的吲哚 |
| US7572807B2 (en) | 2005-06-09 | 2009-08-11 | Bristol-Myers Squibb Company | Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors |
| WO2007095124A2 (en) | 2006-02-10 | 2007-08-23 | Transtech Pharma, Inc. | Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors |
| WO2012109263A1 (en) * | 2011-02-07 | 2012-08-16 | The Washington University | Mannoside compounds and methods of use thereof |
| EP2490530A4 (en) * | 2009-10-22 | 2014-01-22 | Univ Washington | COMPOUNDS AND METHOD FOR THE TREATMENT OF BACTERIAL INFECTIONS |
| SG181115A1 (en) | 2009-12-14 | 2012-07-30 | Univ Basel | Mannose derivatives as antagonists of bacterial adhesion |
| US8802078B2 (en) * | 2011-03-11 | 2014-08-12 | University Of Houston | Compositions and methods for modifying a silicone surface for prolonged interference against pathogen colonization |
| JP6073296B2 (ja) | 2011-05-27 | 2017-02-01 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | 重合性化合物、および、液晶媒体および液晶ディスプレイにおけるそれらの使用 |
| WO2012164074A1 (en) * | 2011-06-03 | 2012-12-06 | University Of Basel | Mannose phosphate derivatives as antagonists of bacterial adhesion |
| WO2013134415A1 (en) | 2012-03-07 | 2013-09-12 | Vertex Pharmaceuticals Incorporated | Mannose derivatives for treating bacterial infections |
| US20140107049A1 (en) | 2012-10-04 | 2014-04-17 | Vertex Pharmaceuticals Incorporated | Mannose derivatives for treating bacterial infections |
| JP6412506B2 (ja) * | 2012-12-18 | 2018-10-24 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 細菌感染を処置するためのマンノース誘導体 |
-
2014
- 2014-03-12 CA CA2905019A patent/CA2905019C/en active Active
- 2014-03-12 EP EP14721598.2A patent/EP2970353B1/en active Active
- 2014-03-12 DK DK14721598.2T patent/DK2970353T3/en active
- 2014-03-12 CN CN201480024363.7A patent/CN105164142B/zh active Active
- 2014-03-12 RU RU2015143165A patent/RU2678327C2/ru active
- 2014-03-12 AU AU2014248717A patent/AU2014248717B2/en active Active
- 2014-03-12 KR KR1020157028668A patent/KR102249702B1/ko active IP Right Grant
- 2014-03-12 MX MX2015012472A patent/MX2015012472A/es active IP Right Grant
- 2014-03-12 WO PCT/US2014/024411 patent/WO2014165107A2/en active Application Filing
- 2014-03-12 JP JP2016501525A patent/JP6373352B2/ja active Active
- 2014-03-12 US US14/206,303 patent/US9890176B2/en active Active
- 2014-03-12 ES ES14721598.2T patent/ES2677115T3/es active Active
- 2014-03-12 PL PL14721598T patent/PL2970353T3/pl unknown
-
2015
- 2015-09-09 IL IL241358A patent/IL241358B/en active IP Right Grant
- 2015-09-30 ZA ZA2015/07241A patent/ZA201507241B/en unknown
-
2016
- 2016-02-03 HK HK16101243.5A patent/HK1213268A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2677115T3 (es) | 2018-07-30 |
| EP2970353B1 (en) | 2018-04-18 |
| KR102249702B1 (ko) | 2021-05-10 |
| NZ711932A (en) | 2020-12-18 |
| CA2905019C (en) | 2021-07-06 |
| US9890176B2 (en) | 2018-02-13 |
| WO2014165107A3 (en) | 2015-02-26 |
| IL241358A0 (en) | 2015-11-30 |
| KR20150126692A (ko) | 2015-11-12 |
| JP6373352B2 (ja) | 2018-08-15 |
| US20140274930A1 (en) | 2014-09-18 |
| EP2970353A2 (en) | 2016-01-20 |
| WO2014165107A2 (en) | 2014-10-09 |
| JP2016512538A (ja) | 2016-04-28 |
| AU2014248717A1 (en) | 2015-09-24 |
| RU2678327C2 (ru) | 2019-01-28 |
| ZA201507241B (en) | 2018-12-19 |
| CN105164142B (zh) | 2019-03-08 |
| MX2015012472A (es) | 2016-02-10 |
| PL2970353T3 (pl) | 2018-10-31 |
| CA2905019A1 (en) | 2014-10-09 |
| CN105164142A (zh) | 2015-12-16 |
| RU2015143165A (ru) | 2017-04-17 |
| AU2014248717B2 (en) | 2018-03-29 |
| IL241358B (en) | 2018-07-31 |
| DK2970353T3 (en) | 2018-07-09 |
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