PL2970353T3 - Pochodne mannozy do leczenia infekcji bakteryjnych - Google Patents
Pochodne mannozy do leczenia infekcji bakteryjnychInfo
- Publication number
- PL2970353T3 PL2970353T3 PL14721598T PL14721598T PL2970353T3 PL 2970353 T3 PL2970353 T3 PL 2970353T3 PL 14721598 T PL14721598 T PL 14721598T PL 14721598 T PL14721598 T PL 14721598T PL 2970353 T3 PL2970353 T3 PL 2970353T3
- Authority
- PL
- Poland
- Prior art keywords
- bacterial infections
- treating bacterial
- mannose derivatives
- mannose
- derivatives
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 150000002703 mannose derivatives Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361777398P | 2013-03-12 | 2013-03-12 | |
| PCT/US2014/024411 WO2014165107A2 (en) | 2013-03-12 | 2014-03-12 | Mannose derivatives for treating bacterial infections |
| EP14721598.2A EP2970353B1 (en) | 2013-03-12 | 2014-03-12 | Mannose derivatives for treating bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2970353T3 true PL2970353T3 (pl) | 2018-10-31 |
Family
ID=50639929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14721598T PL2970353T3 (pl) | 2013-03-12 | 2014-03-12 | Pochodne mannozy do leczenia infekcji bakteryjnych |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9890176B2 (pl) |
| EP (1) | EP2970353B1 (pl) |
| JP (1) | JP6373352B2 (pl) |
| KR (1) | KR102249702B1 (pl) |
| CN (1) | CN105164142B (pl) |
| AU (1) | AU2014248717B2 (pl) |
| CA (1) | CA2905019C (pl) |
| DK (1) | DK2970353T3 (pl) |
| ES (1) | ES2677115T3 (pl) |
| HK (1) | HK1213268A1 (pl) |
| IL (1) | IL241358B (pl) |
| MX (1) | MX2015012472A (pl) |
| PL (1) | PL2970353T3 (pl) |
| RU (1) | RU2678327C2 (pl) |
| WO (1) | WO2014165107A2 (pl) |
| ZA (1) | ZA201507241B (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2894536C (en) | 2012-12-18 | 2020-07-28 | Vertex Pharmaceuticals Incorporated | Mannose derivatives for treating bacterial infections |
| US20200002303A1 (en) * | 2016-03-11 | 2020-01-02 | Fimbrion Therapeutics, Inc. | C-glycoside compounds useful for treating disease |
| JP2019509315A (ja) | 2016-03-23 | 2019-04-04 | フィンブリオン セラピューティックス， インコーポレイテッドＦｉｍｂｒｉｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 疾患の処置に有用なＦｉｍＨのマンノース由来アンタゴニスト |
| TWI821328B (zh) | 2018-07-10 | 2023-11-11 | 英商葛蘭素史克智慧財產發展有限公司 | 新穎化合物 |
| US12297223B2 (en) | 2019-05-07 | 2025-05-13 | Glaxosmithkline Intellectual Property Development Limited | Compounds |
| US12351597B2 (en) | 2019-06-19 | 2025-07-08 | Glaxosmithkline Intellectual Property Development Limited | Substituted biphenyl or phenylheteroaryl-mannosides as antagonists of FimH |
| CN113461753B (zh) * | 2020-03-31 | 2023-05-23 | 郑计岳 | 2-炔基甘露糖衍生物及其应用 |
| CN115253144A (zh) * | 2022-08-09 | 2022-11-01 | 青岛嘉智生物技术有限公司 | 针对戊二醛类消毒剂的中和剂及其制备方法 |
| CN120004912B (zh) * | 2024-12-24 | 2025-11-04 | 南华大学 | 一种三环前列腺素d2代谢物甲酯的制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0619317A1 (en) | 1993-04-07 | 1994-10-12 | Centre National De La Recherche Scientifique | An expeditious synthesis of C-disaccharides using a temporary ketal connection |
| JPH09505309A (ja) * | 1993-11-18 | 1997-05-27 | ワシントン・ユニバーシティ | 細菌感染の治療および予防のための化合物および医薬組成物 |
| AU6024998A (en) | 1997-01-15 | 1998-08-07 | Glycomed Incorporated | Aryl c-glycoside compounds and sulfated esters thereof |
| AUPQ872300A0 (en) | 2000-07-11 | 2000-08-03 | Praxis Pharmaceuticals Pty Ltd | Compounds and methods |
| WO2004091499A2 (en) | 2003-04-09 | 2004-10-28 | Neose Technologies, Inc. | Intracellular formation of peptide conjugates |
| US20080171706A1 (en) * | 2004-03-23 | 2008-07-17 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections |
| FR2876798A1 (fr) | 2004-10-14 | 2006-04-21 | Univ Clermont Auvergne | Diagnostic et traitement de la maladie de crohn |
| US20080249091A1 (en) | 2005-01-19 | 2008-10-09 | Benjamin Pelcman | Indoles Useful in the Treatment of Inflammation |
| JP2008527028A (ja) | 2005-01-19 | 2008-07-24 | バイオリポックス エービー | 炎症の治療に有用なインドール類 |
| JP2008527030A (ja) | 2005-01-19 | 2008-07-24 | バイオリポックス エービー | 炎症の治療に有用なインドール類 |
| BRPI0519774A2 (pt) | 2005-01-19 | 2009-02-10 | Biolipox Ab | composto ou um sal farmaceuticamente aceitÁvel do mesmo, formulaÇço farmacÊutica, uso de um composto ou um sal farmaceuticamente aceitÁvel do mesmo, mÉtodo de tratamento de uma doenÇa em que inibiÇço da atividade de um membro da famÍlia mapeg É desejada e/ou necessÁria, produto combinado, e, processo para a preparaÇço de um composto |
| US7572807B2 (en) | 2005-06-09 | 2009-08-11 | Bristol-Myers Squibb Company | Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors |
| CN102633783A (zh) | 2006-02-10 | 2012-08-15 | 转化技术制药公司 | 作为Aurora激酶抑制剂的苯并唑系衍生物、组合物和使用方法 |
| WO2012109263A1 (en) * | 2011-02-07 | 2012-08-16 | The Washington University | Mannoside compounds and methods of use thereof |
| WO2011050323A1 (en) | 2009-10-22 | 2011-04-28 | The Washington University | Compounds and methods for treating bacterial infections |
| NZ601176A (en) * | 2009-12-14 | 2014-03-28 | Univ Basel | Mannose derivatives as antagonists of bacterial adhesion |
| WO2012125576A1 (en) | 2011-03-11 | 2012-09-20 | University Of Houston | Compositions and methods for modifying a silicone surface for prolonged interference against pathogen colonoization |
| EP2714844B1 (de) | 2011-05-27 | 2016-12-28 | Merck Patent GmbH | Polymerisierbare verbindungen und ihre verwendung in flüssigkristallmedien und flüssigkristallanzeigen |
| WO2012164074A1 (en) | 2011-06-03 | 2012-12-06 | University Of Basel | Mannose phosphate derivatives as antagonists of bacterial adhesion |
| US20130261077A1 (en) | 2012-03-07 | 2013-10-03 | Vertex Pharmaceuticals Incorporated | Mannose derivatives for treating bacterial infections |
| US20140107049A1 (en) | 2012-10-04 | 2014-04-17 | Vertex Pharmaceuticals Incorporated | Mannose derivatives for treating bacterial infections |
| CA2894536C (en) | 2012-12-18 | 2020-07-28 | Vertex Pharmaceuticals Incorporated | Mannose derivatives for treating bacterial infections |
-
2014
- 2014-03-12 MX MX2015012472A patent/MX2015012472A/es active IP Right Grant
- 2014-03-12 EP EP14721598.2A patent/EP2970353B1/en active Active
- 2014-03-12 US US14/206,303 patent/US9890176B2/en active Active
- 2014-03-12 HK HK16101243.5A patent/HK1213268A1/zh unknown
- 2014-03-12 WO PCT/US2014/024411 patent/WO2014165107A2/en not_active Ceased
- 2014-03-12 RU RU2015143165A patent/RU2678327C2/ru active
- 2014-03-12 CN CN201480024363.7A patent/CN105164142B/zh not_active Expired - Fee Related
- 2014-03-12 AU AU2014248717A patent/AU2014248717B2/en not_active Ceased
- 2014-03-12 KR KR1020157028668A patent/KR102249702B1/ko not_active Expired - Fee Related
- 2014-03-12 PL PL14721598T patent/PL2970353T3/pl unknown
- 2014-03-12 DK DK14721598.2T patent/DK2970353T3/en active
- 2014-03-12 ES ES14721598.2T patent/ES2677115T3/es active Active
- 2014-03-12 JP JP2016501525A patent/JP6373352B2/ja not_active Expired - Fee Related
- 2014-03-12 CA CA2905019A patent/CA2905019C/en active Active
-
2015
- 2015-09-09 IL IL241358A patent/IL241358B/en active IP Right Grant
- 2015-09-30 ZA ZA2015/07241A patent/ZA201507241B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN105164142A (zh) | 2015-12-16 |
| AU2014248717A1 (en) | 2015-09-24 |
| RU2015143165A (ru) | 2017-04-17 |
| AU2014248717B2 (en) | 2018-03-29 |
| US20140274930A1 (en) | 2014-09-18 |
| KR102249702B1 (ko) | 2021-05-10 |
| IL241358A0 (en) | 2015-11-30 |
| CA2905019C (en) | 2021-07-06 |
| DK2970353T3 (en) | 2018-07-09 |
| WO2014165107A2 (en) | 2014-10-09 |
| RU2678327C2 (ru) | 2019-01-28 |
| EP2970353A2 (en) | 2016-01-20 |
| MX2015012472A (es) | 2016-02-10 |
| US9890176B2 (en) | 2018-02-13 |
| JP2016512538A (ja) | 2016-04-28 |
| HK1213268A1 (zh) | 2016-06-30 |
| EP2970353B1 (en) | 2018-04-18 |
| ES2677115T3 (es) | 2018-07-30 |
| WO2014165107A3 (en) | 2015-02-26 |
| ZA201507241B (en) | 2018-12-19 |
| KR20150126692A (ko) | 2015-11-12 |
| CN105164142B (zh) | 2019-03-08 |
| JP6373352B2 (ja) | 2018-08-15 |
| CA2905019A1 (en) | 2014-10-09 |
| NZ711932A (en) | 2020-12-18 |
| IL241358B (en) | 2018-07-31 |
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