PT2844226T - Composições oftálmicas com proteção de dissecação e retenção melhoradas - Google Patents

Composições oftálmicas com proteção de dissecação e retenção melhoradas

Info

Publication number
PT2844226T
PT2844226T PT137236238T PT13723623T PT2844226T PT 2844226 T PT2844226 T PT 2844226T PT 137236238 T PT137236238 T PT 137236238T PT 13723623 T PT13723623 T PT 13723623T PT 2844226 T PT2844226 T PT 2844226T
Authority
PT
Portugal
Prior art keywords
dessication
retention
protection
improved
ophthalmic compositions
Prior art date
Application number
PT137236238T
Other languages
English (en)
Portuguese (pt)
Inventor
W Davis James
Allen Ketelson Howard
E Campbell Elaine
L Meadows David
Rangarajan Rekha
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT2844226T publication Critical patent/PT2844226T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT137236238T 2012-05-04 2013-05-03 Composições oftálmicas com proteção de dissecação e retenção melhoradas PT2844226T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261642901P 2012-05-04 2012-05-04

Publications (1)

Publication Number Publication Date
PT2844226T true PT2844226T (pt) 2019-12-16

Family

ID=48464107

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137236238T PT2844226T (pt) 2012-05-04 2013-05-03 Composições oftálmicas com proteção de dissecação e retenção melhoradas

Country Status (19)

Country Link
US (6) US20130296264A1 (enExample)
EP (1) EP2844226B1 (enExample)
KR (1) KR102076033B1 (enExample)
CN (2) CN104379131A (enExample)
AR (1) AR090930A1 (enExample)
AU (1) AU2013256144B2 (enExample)
BR (1) BR112014027582B1 (enExample)
CA (1) CA2872622C (enExample)
DK (1) DK2844226T3 (enExample)
ES (1) ES2761373T3 (enExample)
IN (1) IN2014MN02248A (enExample)
MX (1) MX362266B (enExample)
PH (1) PH12014502571B1 (enExample)
PL (1) PL2844226T3 (enExample)
PT (1) PT2844226T (enExample)
RU (1) RU2659207C2 (enExample)
UA (1) UA113434C2 (enExample)
WO (1) WO2013166399A1 (enExample)
ZA (1) ZA201408490B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3613423T (pt) 2013-07-10 2022-12-07 Matrix Biology Inst Composições de hialuronano de elevada elasticidade e suas utilizações
US10245324B2 (en) * 2014-10-31 2019-04-02 Johnson & Johnson Consumer Inc. Ophthalmic composition
CN105311042B (zh) * 2015-09-07 2019-04-12 广州国宇医药科技有限公司 一种糖醇组合物在制备治疗干眼症的药物中的应用
PT3352766T (pt) 2015-09-24 2022-03-22 Matrix Biology Inst Composições de hialuronano de elevada elasticidade e processos para o seu uso
US10632202B2 (en) 2016-03-04 2020-04-28 Johnson & Johnson Consumer Inc. Preservative containing compositions
TWI913170B (zh) * 2018-02-21 2026-01-21 瑞士商愛爾康公司 基於脂質的眼用乳劑
TWI826685B (zh) 2019-05-02 2023-12-21 瑞士商愛爾康公司 可溶解聚合物眼睛插入物及其使用方法
TWI757773B (zh) * 2019-06-28 2022-03-11 瑞士商愛爾康公司 眼用組成物
CN114191378A (zh) * 2021-11-23 2022-03-18 温州医科大学附属眼视光医院 一种地夸磷索缓释凝胶及其制备方法与应用
AU2025233965A1 (en) 2024-03-04 2026-07-16 Alcon Inc. Carbamoylphenylboronic acid-containing acrylic monomers and uses thereof
WO2026115440A1 (en) 2024-11-27 2026-06-04 Alcon Inc. Stable ophthalmic emulsion
US20260144812A1 (en) 2024-11-27 2026-05-28 Alcon Inc. Antioxidant ophthalmic emulsion

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09227385A (ja) * 1996-02-29 1997-09-02 Ofutekusu:Kk 眼手術用補助剤
DE69818675T2 (de) 1997-07-29 2004-07-29 Alcon Laboratories, Inc., Fort Worth Galaktomannanpolymere und borat enthaltende augenarzneimittel
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
CA2839849C (en) * 2003-06-13 2017-03-07 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
KR101555291B1 (ko) * 2007-02-09 2015-09-30 알콘, 인코퍼레이티드 세가지 폴리머의 상승성 배합물을 함유하는 안과 조성물
US20090036554A1 (en) 2007-08-01 2009-02-05 Burke Susan E Ophthalmic compositions comprising a terpene compound
US9096819B2 (en) * 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
AR071834A1 (es) * 2008-04-26 2010-07-21 Alcon Res Ltd Sistema polimerico de lagrimas artificiales
US20100087550A1 (en) * 2008-10-06 2010-04-08 Zora Marlowe Formulations with a Tertiary Amine Oxide
NZ603345A (en) * 2010-05-05 2014-12-24 Alcon Res Ltd Stabilized ophthalmic galactomannan formulations

Also Published As

Publication number Publication date
US20230285443A1 (en) 2023-09-14
PL2844226T3 (pl) 2020-04-30
CN109157539A (zh) 2019-01-08
US11376275B2 (en) 2022-07-05
KR102076033B1 (ko) 2020-02-11
AU2013256144B2 (en) 2018-01-18
IN2014MN02248A (enExample) 2015-07-24
PH12014502571A1 (en) 2015-01-21
US11672820B2 (en) 2023-06-13
PH12014502571B1 (en) 2022-04-29
AR090930A1 (es) 2014-12-17
CN104379131A (zh) 2015-02-25
ES2761373T3 (es) 2020-05-19
US20200138853A1 (en) 2020-05-07
MX362266B (es) 2019-01-10
BR112014027582A2 (pt) 2017-06-27
US20220273699A1 (en) 2022-09-01
EP2844226B1 (en) 2019-11-13
EP2844226A1 (en) 2015-03-11
AU2013256144A1 (en) 2014-12-04
CA2872622A1 (en) 2013-11-07
KR20150003868A (ko) 2015-01-09
US20170136057A1 (en) 2017-05-18
RU2014148758A (ru) 2016-06-27
US20210060056A1 (en) 2021-03-04
WO2013166399A1 (en) 2013-11-07
MX2014013444A (es) 2015-05-11
DK2844226T3 (da) 2020-01-02
CA2872622C (en) 2020-07-28
BR112014027582B1 (pt) 2022-05-10
UA113434C2 (uk) 2017-01-25
BR112014027582A8 (pt) 2021-06-15
RU2659207C2 (ru) 2018-06-28
US10828320B2 (en) 2020-11-10
US20130296264A1 (en) 2013-11-07
ZA201408490B (en) 2016-08-31

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