PT3613423T - Composições de hialuronano de elevada elasticidade e suas utilizações - Google Patents
Composições de hialuronano de elevada elasticidade e suas utilizaçõesInfo
- Publication number
- PT3613423T PT3613423T PT192020824T PT19202082T PT3613423T PT 3613423 T PT3613423 T PT 3613423T PT 192020824 T PT192020824 T PT 192020824T PT 19202082 T PT19202082 T PT 19202082T PT 3613423 T PT3613423 T PT 3613423T
- Authority
- PT
- Portugal
- Prior art keywords
- hyaluronan
- compositions
- high elasticity
- elasticity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361844645P | 2013-07-10 | 2013-07-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT3613423T true PT3613423T (pt) | 2022-12-07 |
Family
ID=51261252
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT192020824T PT3613423T (pt) | 2013-07-10 | 2014-07-09 | Composições de hialuronano de elevada elasticidade e suas utilizações |
PT147452999T PT3019177T (pt) | 2013-07-10 | 2014-07-09 | Composições de hialuronano de elevada elasticidade e suas utilizações |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT147452999T PT3019177T (pt) | 2013-07-10 | 2014-07-09 | Composições de hialuronano de elevada elasticidade e suas utilizações |
Country Status (8)
Country | Link |
---|---|
US (4) | US9492474B2 (pt) |
EP (3) | EP3613423B1 (pt) |
JP (5) | JP6357228B2 (pt) |
AR (1) | AR096875A1 (pt) |
ES (2) | ES2933549T3 (pt) |
PL (2) | PL3019177T3 (pt) |
PT (2) | PT3613423T (pt) |
WO (1) | WO2015006460A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9492474B2 (en) | 2013-07-10 | 2016-11-15 | Matrix Biology Institute | Compositions of hyaluronan with high elasticity and uses thereof |
EP3842047B1 (en) | 2015-09-24 | 2024-08-07 | Matrix Biology Institute | High elasticity hyaluronan compositions and methods of use thereof |
ES2976202T3 (es) | 2018-01-10 | 2024-07-26 | The Provost Fellows Scholars And Other Members Of Board Of Trinity College Dublin | Sistema para sellar un canal en tejido |
WO2020144372A1 (en) | 2019-01-10 | 2020-07-16 | The Provost, Fellows, Scholars And Other Members Of Board Of Trinity College Dublin | Composite viscoelastic hydrogel, and uses thereof for sealing a channel in tissue |
WO2020232539A1 (en) | 2019-05-17 | 2020-11-26 | The Governing Council Of The University Of Toronto | Sustained release local anesthetic hydrogel composition |
Family Cites Families (97)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4141973A (en) | 1975-10-17 | 1979-02-27 | Biotrics, Inc. | Ultrapure hyaluronic acid and the use thereof |
US4517295A (en) | 1983-02-18 | 1985-05-14 | Diagnostic, Inc. | Hyaluronic acid from bacterial culture |
NO169637C (no) | 1983-10-11 | 1992-07-22 | Fidia Spa | Fremgangsmaate for fremstilling av terapeutisk aktive hyaluronsyre-fraksjoner |
IT1198449B (it) | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
US5403592A (en) | 1987-08-25 | 1995-04-04 | Macnaught Pty Limited | Lubricant composition for rheumatism |
AU620821B2 (en) | 1987-08-25 | 1992-02-27 | Macnaught Pty Limited | Hyaluronic acid lubricating compounds |
DE69017559T3 (de) | 1989-07-24 | 2002-06-06 | Allergan Pharmaceuticals (Ireland) Ltd., Irvine | Stabile Lösung von Hyaluronat in einem isotonen Salzmilieu. |
CA2060223C (en) | 1991-02-12 | 1999-07-20 | Clarence C. Lee | Injectable medical lubricating fluid composition and method of use |
US5234914A (en) | 1991-06-11 | 1993-08-10 | Patent Biopharmaceutics, Inc. | Methods of treating hemorrhoids and anorecial disease |
AU682670B2 (en) | 1993-02-05 | 1997-10-16 | Becton Dickinson & Company | Syringe needle isolation device |
US5624915A (en) | 1993-08-04 | 1997-04-29 | Patent Biopharmaceutics, Inc. | Hyaluronic acid-urea pharmaceutical compositions and uses |
US5607400A (en) | 1995-05-19 | 1997-03-04 | Becton, Dickinson And Company | Pre-fillable syringe and stopper assembly therefor |
IT1277707B1 (it) * | 1995-12-22 | 1997-11-11 | Chemedica Sa | Formulazione oftalmica a base di ialuronato di sodio per uso nella chirurgia oculare |
JPH09173450A (ja) | 1995-12-26 | 1997-07-08 | Nissho Corp | プレフィルドシリンジ |
JP3293122B2 (ja) | 1996-12-13 | 2002-06-17 | ニプロ株式会社 | プレフィルドシリンジ |
SE9700827D0 (sv) | 1997-03-07 | 1997-03-07 | Pharmacia & Upjohn Ab | Ophthalmic composition |
RU2126669C1 (ru) | 1997-04-25 | 1999-02-27 | Новокузнецкий государственный институт усовершенствования врачей | Способ лечения синдрома сухого глаза |
SE9703425D0 (sv) | 1997-09-23 | 1997-09-23 | Pharmacia & Upjohn Ab | Prefilled ampooules and manufacture thereof |
DE19751219A1 (de) | 1997-11-19 | 1999-05-27 | Vetter & Co Apotheker | Spritze, insbesondere vorgefüllte Spritze, oder Karpule |
JP4216467B2 (ja) | 1998-03-13 | 2009-01-28 | ベクトン・ディキンソン・アンド・カンパニー | 医療装置の組立ておよび包装方法 |
ITPD980169A1 (it) | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
JP3591636B2 (ja) | 2000-04-03 | 2004-11-24 | ニプロ株式会社 | プレフィルドシリンジ |
DK1142566T3 (da) | 2000-04-07 | 2004-02-09 | Medidom Lab | Oftalmologiske formuleringer på basis af ciclosporin, hyaluronsyre og polysorbat |
US7635489B2 (en) | 2001-05-18 | 2009-12-22 | Leneau Holdings, Llc | Ingestion of hyaluronic acid for improved joint health |
JP2003119147A (ja) * | 2001-10-10 | 2003-04-23 | Raku:Kk | ヒアルロン酸化合物の水溶液組成物 |
AU2002360939A1 (en) | 2001-11-21 | 2003-06-10 | Novartis Ag | Composition for stabilizing hyaluronic acid |
US7820194B2 (en) | 2001-12-21 | 2010-10-26 | Alcon, Inc. | Combinations of viscoelastics for use during surgery |
JP4141156B2 (ja) | 2002-03-15 | 2008-08-27 | 日本ベクトン・ディッキンソン株式会社 | プランジャ後退制限機構付きプレフィルドシリンジ |
WO2004004811A1 (ja) | 2002-07-02 | 2004-01-15 | Terumo Kabushiki Kaisha | シリンジおよびプレフィルドシリンジ |
EP1539193A4 (en) | 2002-07-03 | 2010-05-05 | Pericor Science Inc | HYALURONIC ACID COMPOSITIONS AND METHODS OF USE |
WO2004028536A1 (en) | 2002-09-30 | 2004-04-08 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
DE10254321A1 (de) | 2002-11-21 | 2004-06-17 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | Vorgefüllte Spritze |
JP2004229750A (ja) | 2003-01-28 | 2004-08-19 | Nipro Corp | プレフィルドシリンジ及びそのバレルの製造方法 |
US20040167480A1 (en) * | 2003-02-21 | 2004-08-26 | Advanced Medical Optics, Inc. | Administration of multiple viscoelastic solutions with a multi-compartment syringe |
JP2004262777A (ja) | 2003-02-27 | 2004-09-24 | Shiseido Co Ltd | アセチル化ヒアルロン酸含有眼用医薬組成物 |
FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
AR044302A1 (es) | 2003-05-13 | 2005-09-07 | Ares Trading Sa | Formulaciones con proteinas liquidas estabilizadas en recipientes farmaceuticos |
US20050059639A1 (en) | 2003-09-11 | 2005-03-17 | Wei Edward T. | Ophthalmic compositions and method for treating eye discomfort and pain |
US20050075611A1 (en) | 2003-10-01 | 2005-04-07 | Hetzler Kevin G. | Low extractable, thermoplastic syringe and tip cap |
US20090148527A1 (en) | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
WO2005110439A2 (en) | 2004-05-07 | 2005-11-24 | S.K. Pharmaceuticals, Inc. | Stabilized hyaluronan preparations and related methods |
US8372814B2 (en) | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
WO2006067608A1 (en) | 2004-12-22 | 2006-06-29 | Laboratoire Medidom S.A. | Aqueous formulations based on sodium hyaluronate for parenteral use |
SI2664334T1 (sl) * | 2004-12-30 | 2015-06-30 | Genzyme Corporation | Reĺ˝imi za intraartikularno viskosuplemantacijo |
US8388995B1 (en) | 2006-02-03 | 2013-03-05 | Auburn University | Controlled and extended delivery of hyaluronic acid and comfort molecules via a contact lens platform |
US9238003B2 (en) | 2005-02-04 | 2016-01-19 | Auburn University | Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules |
ITPD20050056A1 (it) | 2005-03-02 | 2006-09-03 | Fidia Farmaceutici | Derivati ammidici del'acido ialuronico in osteoartrosi |
US7767710B2 (en) | 2005-05-25 | 2010-08-03 | Calosyn Pharma, Inc. | Method for treating osteoarthritis |
DE102005055275A1 (de) | 2005-11-17 | 2007-05-24 | Ursapharm Arzneimittel Gmbh & Co. Kg | Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung |
JP2009516765A (ja) * | 2005-11-22 | 2009-04-23 | サントル ナシオナル ドゥ ラ ルシェルシェ シアンティフィク | 新規ヒアルロン酸誘導体、その製造方法及びその使用 |
US7988675B2 (en) | 2005-12-08 | 2011-08-02 | West Pharmaceutical Services Of Delaware, Inc. | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
EP1968614A2 (en) | 2005-12-14 | 2008-09-17 | Anika Therapeutics Inc. | Treatment of arthritis and other musculoskeletal disorders with crosslinked hyaluronic acid |
JP4682850B2 (ja) | 2006-01-12 | 2011-05-11 | ニプロ株式会社 | プレフィルドシリンジ |
US20070254841A1 (en) | 2006-01-25 | 2007-11-01 | Ophthalmic Research Associates, Inc. | Formulations and methods for treating dry eye |
US7674781B2 (en) | 2006-04-28 | 2010-03-09 | Heather Sheardown | Hyaluronic acid-retaining polymers |
AR062046A1 (es) | 2006-07-25 | 2008-08-10 | Osmotica Pharmaceutical Argentina S A | Soluciones oftalmicas |
US8377468B2 (en) | 2006-08-28 | 2013-02-19 | Rexaderm, Inc. | Dry wound dressing and drug delivery system |
ITMI20061668A1 (it) | 2006-09-01 | 2008-03-02 | Schiena Michele Giuseppe Di | Composizione a base di acido ialuronico e suoi sali per il trattamento di lesioni epiteliali |
JP2010510347A (ja) | 2006-11-17 | 2010-04-02 | エージェンシー フォー サイエンス, テクノロジー アンド リサーチ | 架橋性湿潤剤を有する多孔質ポリマー材料 |
BRPI0621470A2 (pt) | 2006-12-05 | 2011-12-13 | Glycoscience Lab Inc | agente terapêutico para artrite degenerativa |
FR2918276B1 (fr) | 2007-07-02 | 2010-01-22 | Anteis Sa | "utilisation d'un gel de polysaccharide(s)naturel(s)pour la preparation d'une formulation injectable de traitement des degenerescences articulaires" |
US8093365B2 (en) | 2008-03-03 | 2012-01-10 | New York University | Biocompatible materials containing stable complexes method of TSG-6 and hyaluronan and method of using same |
WO2009122541A1 (ja) * | 2008-03-31 | 2009-10-08 | Inui Hiroaki | ヒト胚の体外受精及び培養用培養液及びヒト胚の体外受精及び培養方法 |
CA2719666C (en) | 2008-04-04 | 2016-08-16 | Glenn Prestwich | Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof |
FR2938187B1 (fr) | 2008-11-07 | 2012-08-17 | Anteis Sa | Composition injectable a base d'acide hyaluronique ou l'un de ses sels, de polyols et de lidocaine, sterilisee a la chaleur |
ES2538835T3 (es) * | 2009-01-07 | 2015-06-24 | Robert John Petrella | Tratamiento de lesiones de tejidos blandos utilizando el ácido hialurónico y la toxina botulínica |
US20100178317A1 (en) | 2009-01-09 | 2010-07-15 | Burke Susan E | Lens Care Solutions with Hyaluronic Acid |
US8979821B2 (en) | 2009-04-14 | 2015-03-17 | Fezza Family Properties, Llc | Lacrimal filler |
US20100303915A1 (en) | 2009-06-02 | 2010-12-02 | Abbott Medical Optics Inc. | Therapeutic opthalmic emulsions |
RU2538696C2 (ru) | 2009-06-05 | 2015-01-10 | Эдвард Так ВЭЙ | Лечение дискомфорта глаз путем местного применения охлаждающего агента на наружной поверхности века |
WO2011031852A1 (en) | 2009-09-10 | 2011-03-17 | Boston Foundation For Sight | Sodium channel blocker delivery system with scleral lens |
AU2010303414B2 (en) | 2009-10-07 | 2016-01-07 | Genogen, Inc. | Methods and compositions for skin regeneration |
US20110171310A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie, Sas | Hydrogel compositions comprising vasoconstricting and anti-hemorrhagic agents for dermatological use |
EP4062950A1 (en) | 2010-03-22 | 2022-09-28 | Allergan, Inc. | Syringe comprising dermal filler for soft tissue augmentation |
US20130209531A1 (en) | 2010-06-08 | 2013-08-15 | University Of Utah Research Foundation | Applications of partially and fully sulfated hyaluronan |
CA2809893A1 (en) | 2010-09-02 | 2012-03-08 | Mcmaster University | Hyaluronic acid-containing biopolymers |
DK2614838T3 (en) | 2010-09-10 | 2016-05-02 | Santen Pharmaceutical Co Ltd | Diquafosol and hyaluronic acid or salts thereof for the treatment of dry eyes |
US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
WO2012143876A1 (en) * | 2011-04-19 | 2012-10-26 | Anteis S.A. | A sterile and injectable aqueous formulation for administration in the intra-articular space of an intra-articular joint |
GB201118586D0 (en) | 2011-10-27 | 2011-12-07 | Turzi Antoine | New A-PRP medical device, manufacturing machine and process |
DK2596796T3 (da) | 2011-11-24 | 2014-01-27 | Quimera Ingenieria Biomedica S L | Kompleks opnået af hyaluronsyre eller et salt deraf samt chondroitinsulfatblandinger |
US20150018305A1 (en) | 2012-02-22 | 2015-01-15 | Hyaluronan Research Institute, Inc. | Sirtuin inducer, tissue repairing agent, hepatocyte growth factor inducer, tissue homeostasis maintenance agent, and tlr4 agonist, having hyaluronic acid fragment as active ingredient |
US20150037422A1 (en) | 2012-02-22 | 2015-02-05 | Trustees Of Tufts College | Compositions and methods for ocular delivery of a therapeutic agent |
UA113434C2 (uk) | 2012-05-04 | 2017-01-25 | Алкон Рісерч, Лтд. | Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням |
FR2991876B1 (fr) | 2012-06-13 | 2014-11-21 | Vivacy Lab | Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate |
FR2994846B1 (fr) | 2012-08-29 | 2014-12-26 | Vivacy Lab | Composition, sterilisee, comprenant au moins un acide hyaluronique et de l'ascorbyl phosphate de magnesium |
EP2950783B1 (en) | 2013-02-01 | 2019-05-15 | Allergan, Inc. | Artificial tears comprising sodium hyaluronate and carboxymethylcellulose |
US9226938B2 (en) | 2013-03-14 | 2016-01-05 | RMG Rehabilitation Management Group, LP | Combinatorial therapy for treatment of osteoarthritis of the knee |
EP2979539B1 (en) | 2013-03-25 | 2017-12-20 | National University Corporation Tokyo University Of Agriculture and Technology | Plant cultivation method |
ITMI20130883A1 (it) | 2013-05-30 | 2014-12-01 | Eurores S R L | Composizioni farmaceutiche comprendenti collagene e sodio ialuronato |
US9492474B2 (en) | 2013-07-10 | 2016-11-15 | Matrix Biology Institute | Compositions of hyaluronan with high elasticity and uses thereof |
WO2015074137A1 (en) | 2013-11-20 | 2015-05-28 | Mary Lynch | Compositions and methods for treatment of ocular inflammation and pain |
US9187576B2 (en) | 2013-11-25 | 2015-11-17 | Deuteria Biomaterials, Llc | Deuterium-enriched hyaluronan |
FR3015290B1 (fr) | 2013-12-23 | 2017-01-13 | Lab Vivacy | Compositions d'acide hyaluronique compreant de la mepivacaine |
EP3842047B1 (en) | 2015-09-24 | 2024-08-07 | Matrix Biology Institute | High elasticity hyaluronan compositions and methods of use thereof |
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2014
- 2014-07-09 US US14/327,321 patent/US9492474B2/en active Active
- 2014-07-09 ES ES19202082T patent/ES2933549T3/es active Active
- 2014-07-09 PT PT192020824T patent/PT3613423T/pt unknown
- 2014-07-09 WO PCT/US2014/045973 patent/WO2015006460A1/en active Application Filing
- 2014-07-09 EP EP19202082.4A patent/EP3613423B1/en active Active
- 2014-07-09 EP EP14745299.9A patent/EP3019177B1/en active Active
- 2014-07-09 EP EP22196829.0A patent/EP4137139A1/en active Pending
- 2014-07-09 PL PL14745299T patent/PL3019177T3/pl unknown
- 2014-07-09 JP JP2016525455A patent/JP6357228B2/ja active Active
- 2014-07-09 ES ES14745299T patent/ES2837626T3/es active Active
- 2014-07-09 PT PT147452999T patent/PT3019177T/pt unknown
- 2014-07-09 PL PL19202082.4T patent/PL3613423T3/pl unknown
- 2014-07-10 AR ARP140102559A patent/AR096875A1/es not_active Application Discontinuation
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2016
- 2016-10-11 US US15/290,107 patent/US10383890B2/en active Active
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2018
- 2018-06-15 JP JP2018114766A patent/JP6598929B2/ja active Active
-
2019
- 2019-07-02 US US16/460,511 patent/US10933085B2/en active Active
- 2019-10-01 JP JP2019181618A patent/JP7025039B2/ja active Active
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2021
- 2021-01-26 US US17/158,481 patent/US11524027B2/en active Active
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2022
- 2022-02-03 JP JP2022015509A patent/JP2022058871A/ja not_active Withdrawn
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2024
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JP2019214632A (ja) | 2019-12-19 |
US20210161947A1 (en) | 2021-06-03 |
ES2837626T3 (es) | 2021-07-01 |
EP4137139A1 (en) | 2023-02-22 |
PL3613423T3 (pl) | 2023-02-13 |
EP3613423A1 (en) | 2020-02-26 |
JP6598929B2 (ja) | 2019-10-30 |
JP2018138622A (ja) | 2018-09-06 |
US20170071974A1 (en) | 2017-03-16 |
US20150018303A1 (en) | 2015-01-15 |
WO2015006460A1 (en) | 2015-01-15 |
JP2016526573A (ja) | 2016-09-05 |
JP2024028669A (ja) | 2024-03-04 |
EP3019177B1 (en) | 2020-11-04 |
PL3019177T3 (pl) | 2021-04-19 |
EP3019177A1 (en) | 2016-05-18 |
PT3019177T (pt) | 2020-12-30 |
JP7025039B2 (ja) | 2022-02-24 |
US11524027B2 (en) | 2022-12-13 |
AR096875A1 (es) | 2016-02-03 |
US20200030363A1 (en) | 2020-01-30 |
JP6357228B2 (ja) | 2018-07-11 |
US9492474B2 (en) | 2016-11-15 |
JP2022058871A (ja) | 2022-04-12 |
ES2933549T3 (es) | 2023-02-10 |
EP3613423B1 (en) | 2022-10-26 |
US10933085B2 (en) | 2021-03-02 |
US10383890B2 (en) | 2019-08-20 |
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