PT2524700E - Vacina de glicoproteína mucinosa (muc-1) - Google Patents

Vacina de glicoproteína mucinosa (muc-1) Download PDF

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Publication number
PT2524700E
PT2524700E PT111962288T PT11196228T PT2524700E PT 2524700 E PT2524700 E PT 2524700E PT 111962288 T PT111962288 T PT 111962288T PT 11196228 T PT11196228 T PT 11196228T PT 2524700 E PT2524700 E PT 2524700E
Authority
PT
Portugal
Prior art keywords
muc
vaccine
treatment
prostate cancer
mucinous glycoprotein
Prior art date
Application number
PT111962288T
Other languages
English (en)
Inventor
Michael Longenecker
Original Assignee
Oncothyreon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncothyreon Inc filed Critical Oncothyreon Inc
Publication of PT2524700E publication Critical patent/PT2524700E/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001169Tumor associated carbohydrates
    • A61K39/00117Mucins, e.g. MUC-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/664Amides of phosphorus acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT111962288T 2004-04-01 2005-04-01 Vacina de glicoproteína mucinosa (muc-1) PT2524700E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55813904P 2004-04-01 2004-04-01
US57680404P 2004-06-04 2004-06-04

Publications (1)

Publication Number Publication Date
PT2524700E true PT2524700E (pt) 2016-02-29

Family

ID=35428714

Family Applications (2)

Application Number Title Priority Date Filing Date
PT57696098T PT1737485E (pt) 2004-04-01 2005-04-01 Vacina da glicoproteína mucina (muc-1)
PT111962288T PT2524700E (pt) 2004-04-01 2005-04-01 Vacina de glicoproteína mucinosa (muc-1)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT57696098T PT1737485E (pt) 2004-04-01 2005-04-01 Vacina da glicoproteína mucina (muc-1)

Country Status (16)

Country Link
US (2) US9173929B2 (pt)
EP (2) EP2524700B1 (pt)
JP (3) JP5590768B2 (pt)
CN (2) CN103933556A (pt)
AR (1) AR051350A1 (pt)
AU (1) AU2005244675B2 (pt)
BR (1) BRPI0509552A (pt)
CA (1) CA2562990A1 (pt)
DK (2) DK2524700T3 (pt)
ES (2) ES2560808T3 (pt)
HK (1) HK1109574A1 (pt)
HU (1) HUE027378T2 (pt)
PL (2) PL2524700T3 (pt)
PT (2) PT1737485E (pt)
TW (2) TW201204410A (pt)
WO (1) WO2005112546A2 (pt)

Families Citing this family (18)

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EP1377275B1 (en) 2001-03-27 2006-10-25 Biomira, Inc. Vaccine for modulating between t1 and t2 immune responses
CA2482477A1 (en) * 2002-04-15 2003-10-30 Biomira, Inc. Synthetic glyco-lipo-peptides as vaccines
TW201204410A (en) 2004-04-01 2012-02-01 Oncothyreon Inc Mucinous glycoprotein (MUC-1) vaccine
PL1896051T3 (pl) * 2005-06-28 2015-04-30 Oncothyreon Inc Sposób leczenia pacjentów szczepionką glikoproteiny mucynowej (muc-1)
AU2012268892B2 (en) * 2005-06-28 2016-05-26 Oncothyreon Inc. Method of Treating Patients with a Mucinous Glycoprotein (MUC-1) Vaccine
US20120039984A1 (en) 2008-07-03 2012-02-16 University Of Georgia Research Foundation, Inc. Glycopeptide and uses thereof
EA020604B1 (ru) * 2008-12-17 2014-12-30 Онкотиреон, Инк. Композиция, содержащая липосомы малого размера, и способ ее получения
WO2011054359A2 (en) 2009-11-06 2011-05-12 University Of Copenhagen Method for early detection of cancer
WO2011133429A1 (en) 2010-04-19 2011-10-27 Ezose Sciences, Inc Cancer-related glycopeptide epitopes, antibodies and methods of use
CA2825972A1 (en) 2011-02-24 2012-08-30 Oncothyreon Inc. Muc1 based glycolipopeptide vaccine with adjuvant
PT3427748T (pt) 2011-06-24 2022-05-03 Nono Inc Terapia de combinação para isquemia
DE102011085695A1 (de) * 2011-11-03 2013-05-08 Jörg Pohl Einmalig dosierte Oxazaphosphorine zur Therapie von Krankheiten
US9241970B2 (en) * 2011-12-13 2016-01-26 Nono Inc. Therapy for subarachnoid hemorrhage and ischemia
CA2912269A1 (en) 2013-05-14 2014-11-20 Merck Patent Gmbh Method of treating lung cancer by vaccination with muc-1 lipopeptide
KR20160043103A (ko) * 2013-08-21 2016-04-20 큐어백 아게 전립선암 치료를 위한 조성물 및 백신
WO2015058831A1 (en) 2013-10-25 2015-04-30 Merck Patent Gmbh Elevated biomarker expression in lung cancer patients responding to treatment with muc-1 lipopeptide vaccines
CN110393797A (zh) * 2019-05-27 2019-11-01 南开大学 基于糖脂佐剂的糖肽疫苗的制备方法与应用
WO2022125956A1 (en) * 2020-12-11 2022-06-16 Trustees Of Boston University Immunomodulatory lipopolysaccharide compositions

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Also Published As

Publication number Publication date
JP5590768B2 (ja) 2014-09-17
DK1737485T3 (da) 2014-08-04
EP1737485B1 (en) 2014-05-07
EP2524700B1 (en) 2015-10-28
BRPI0509552A (pt) 2007-09-18
JP5868125B2 (ja) 2016-02-24
AR051350A1 (es) 2007-01-10
JP2014177479A (ja) 2014-09-25
EP1737485A4 (en) 2008-09-03
US20080131495A1 (en) 2008-06-05
US9173929B2 (en) 2015-11-03
HUE027378T2 (en) 2016-10-28
PL1737485T3 (pl) 2014-10-31
CA2562990A1 (en) 2005-12-01
PT1737485E (pt) 2014-08-22
JP2007530663A (ja) 2007-11-01
DK2524700T3 (en) 2016-02-01
PL2524700T3 (pl) 2016-04-29
CN1997388B (zh) 2014-03-26
EP2524700A1 (en) 2012-11-21
TW200538147A (en) 2005-12-01
ES2560808T3 (es) 2016-02-22
WO2005112546A2 (en) 2005-12-01
TWI395591B (zh) 2013-05-11
US20160082093A1 (en) 2016-03-24
TW201204410A (en) 2012-02-01
WO2005112546A3 (en) 2006-05-04
AU2005244675A1 (en) 2005-12-01
CN103933556A (zh) 2014-07-23
CN1997388A (zh) 2007-07-11
EP1737485A2 (en) 2007-01-03
JP2012092105A (ja) 2012-05-17
HK1109574A1 (en) 2008-06-13
ES2478006T3 (es) 2014-07-18
AU2005244675B2 (en) 2011-07-21

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