PT2063940E - Dispositivo de inalação para fármacos em forma de pó - Google Patents
Dispositivo de inalação para fármacos em forma de pó Download PDFInfo
- Publication number
- PT2063940E PT2063940E PT07857079T PT07857079T PT2063940E PT 2063940 E PT2063940 E PT 2063940E PT 07857079 T PT07857079 T PT 07857079T PT 07857079 T PT07857079 T PT 07857079T PT 2063940 E PT2063940 E PT 2063940E
- Authority
- PT
- Portugal
- Prior art keywords
- inhalation
- slide
- inhalation device
- dosing
- closure cap
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims abstract description 156
- 229940079593 drug Drugs 0.000 title claims abstract description 102
- 239000000843 powder Substances 0.000 title claims abstract description 81
- 230000033001 locomotion Effects 0.000 claims abstract description 104
- 238000011049 filling Methods 0.000 claims abstract description 83
- 238000003860 storage Methods 0.000 claims abstract description 68
- 230000001960 triggered effect Effects 0.000 claims abstract description 41
- 230000005540 biological transmission Effects 0.000 claims description 43
- 230000008878 coupling Effects 0.000 claims description 31
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- 235000013372 meat Nutrition 0.000 claims description 9
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- 238000002347 injection Methods 0.000 claims description 7
- 239000007924 injection Substances 0.000 claims description 7
- 230000002787 reinforcement Effects 0.000 claims description 7
- 229920001684 low density polyethylene Polymers 0.000 claims description 4
- 239000004702 low-density polyethylene Substances 0.000 claims description 4
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
- 230000009977 dual effect Effects 0.000 claims description 3
- 238000005096 rolling process Methods 0.000 claims description 3
- 230000001976 improved effect Effects 0.000 abstract description 5
- 239000000443 aerosol Substances 0.000 description 18
- 239000002274 desiccant Substances 0.000 description 16
- 238000000034 method Methods 0.000 description 15
- 238000004519 manufacturing process Methods 0.000 description 12
- 239000003795 chemical substances by application Substances 0.000 description 11
- 210000004072 lung Anatomy 0.000 description 11
- 230000002829 reductive effect Effects 0.000 description 10
- 230000001681 protective effect Effects 0.000 description 9
- 230000004913 activation Effects 0.000 description 8
- 239000000463 material Substances 0.000 description 8
- 230000008901 benefit Effects 0.000 description 7
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- 239000000945 filler Substances 0.000 description 7
- 239000002245 particle Substances 0.000 description 7
- 230000008569 process Effects 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 239000013543 active substance Substances 0.000 description 5
- 238000013461 design Methods 0.000 description 5
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- 238000012377 drug delivery Methods 0.000 description 4
- 238000001746 injection moulding Methods 0.000 description 4
- 210000002345 respiratory system Anatomy 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000000903 blocking effect Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
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- 239000004033 plastic Substances 0.000 description 3
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- 230000000717 retained effect Effects 0.000 description 3
- 229920002725 thermoplastic elastomer Polymers 0.000 description 3
- 206010057362 Underdose Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
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- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
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- 238000009792 diffusion process Methods 0.000 description 2
- 230000001771 impaired effect Effects 0.000 description 2
- 230000003434 inspiratory effect Effects 0.000 description 2
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- 238000005259 measurement Methods 0.000 description 2
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- 238000002360 preparation method Methods 0.000 description 2
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- 230000035939 shock Effects 0.000 description 2
- 238000000638 solvent extraction Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000014181 Bronchial disease Diseases 0.000 description 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 208000014085 Chronic respiratory disease Diseases 0.000 description 1
- 208000003870 Drug Overdose Diseases 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010033296 Overdoses Diseases 0.000 description 1
- GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 description 1
- 230000035508 accumulation Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 208000024716 acute asthma Diseases 0.000 description 1
- 230000002730 additional effect Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 229960004436 budesonide Drugs 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 231100000725 drug overdose Toxicity 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229940124645 emergency medicine Drugs 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000005429 filling process Methods 0.000 description 1
- 229960002714 fluticasone Drugs 0.000 description 1
- MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 description 1
- 229960002848 formoterol Drugs 0.000 description 1
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000010137 moulding (plastic) Methods 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 229960004017 salmeterol Drugs 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000007781 signaling event Effects 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
- A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
- A61M15/0025—Mouthpieces therefor with caps
- A61M15/0026—Hinged caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/007—Mechanical counters
- A61M15/0071—Mechanical counters having a display or indicator
- A61M15/0076—Mechanical counters having a display or indicator on a drum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/008—Electronic counters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8293—Solar
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Basic Packing Technique (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006062196 | 2006-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2063940E true PT2063940E (pt) | 2012-03-27 |
Family
ID=38290985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT07857079T PT2063940E (pt) | 2006-12-22 | 2007-12-21 | Dispositivo de inalação para fármacos em forma de pó |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US8567394B2 (enExample) |
| EP (1) | EP2063940B1 (enExample) |
| JP (2) | JP5564262B2 (enExample) |
| KR (1) | KR101392649B1 (enExample) |
| CN (1) | CN101600469B (enExample) |
| AR (1) | AR064540A1 (enExample) |
| AT (1) | ATE540717T1 (enExample) |
| AU (1) | AU2007338305B2 (enExample) |
| BR (1) | BRPI0720846A2 (enExample) |
| CA (1) | CA2673553C (enExample) |
| CL (1) | CL2007003813A1 (enExample) |
| CO (1) | CO6220839A2 (enExample) |
| CY (1) | CY1112526T1 (enExample) |
| DK (1) | DK2063940T3 (enExample) |
| EC (1) | ECSP099448A (enExample) |
| EG (1) | EG27057A (enExample) |
| ES (1) | ES2378786T3 (enExample) |
| IL (1) | IL199380A (enExample) |
| MX (1) | MX2009006787A (enExample) |
| MY (1) | MY148020A (enExample) |
| NO (1) | NO20092686L (enExample) |
| NZ (1) | NZ577764A (enExample) |
| PE (1) | PE20081674A1 (enExample) |
| PL (1) | PL2063940T3 (enExample) |
| PT (1) | PT2063940E (enExample) |
| RU (1) | RU2456027C2 (enExample) |
| SI (1) | SI2063940T1 (enExample) |
| TW (1) | TWI473630B (enExample) |
| UA (1) | UA95506C2 (enExample) |
| WO (1) | WO2008077623A1 (enExample) |
| ZA (1) | ZA200904291B (enExample) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| HUE025151T2 (en) | 2004-08-23 | 2016-01-28 | Mannkind Corp | Diceto-piperazine salts for drug delivery |
| KR101486397B1 (ko) | 2005-09-14 | 2015-01-28 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
| KR20080096809A (ko) | 2006-02-22 | 2008-11-03 | 맨카인드 코포레이션 | 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법 |
| EP2037999B1 (en) * | 2006-07-07 | 2016-12-28 | Proteus Digital Health, Inc. | Smart parenteral administration system |
| CA2673553C (en) * | 2006-12-22 | 2014-06-17 | Laboratorios Almirall, S.A. | Breath actuated metering slide for a powder inhaler |
| WO2009029028A1 (en) * | 2007-08-24 | 2009-03-05 | Astrazeneca Ab | Breath- triggered inhaler with dose counter |
| US9125979B2 (en) * | 2007-10-25 | 2015-09-08 | Proteus Digital Health, Inc. | Fluid transfer port information system |
| US8419638B2 (en) * | 2007-11-19 | 2013-04-16 | Proteus Digital Health, Inc. | Body-associated fluid transport structure evaluation devices |
| DK2230934T3 (da) | 2007-12-14 | 2012-11-26 | Aerodesigns Inc | Afgivelse af aerosoliserbare næringsmiddelprodukter |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| MX2010014240A (es) | 2008-06-20 | 2011-03-25 | Mankind Corp | Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion. |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
| US9265910B2 (en) | 2009-05-18 | 2016-02-23 | Boehringer Ingelheim International Gmbh | Adapter, inhalation device, and nebulizer |
| MY157166A (en) | 2009-06-12 | 2016-05-13 | Mankind Corp | Diketopiperazine microparticles with defined specific surface areas |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| FR2952042B1 (fr) * | 2009-11-03 | 2012-01-20 | Valois Sas | Dispositif de distribution de produit fluide. |
| EP2504051B1 (en) | 2009-11-25 | 2019-09-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| CA2781792C (en) | 2009-11-25 | 2019-04-02 | Boehringer Ingelheim International Gmbh | Nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| SG182824A1 (en) | 2010-02-01 | 2012-09-27 | Proteus Biomedical Inc | Two-wrist data gathering system |
| WO2011094606A2 (en) | 2010-02-01 | 2011-08-04 | Proteus Biomedical, Inc. | Data gathering system |
| BR112012033060A2 (pt) | 2010-06-21 | 2018-02-27 | Mannkind Corp | métodos de sistema de liberação de fármaco em pó seco |
| EP2585151B1 (en) | 2010-06-24 | 2018-04-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| US8974450B2 (en) | 2011-02-03 | 2015-03-10 | Covidien Lp | System and method for ablation procedure monitoring using electrodes |
| EP2694220B1 (de) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medizinisches gerät mit behälter |
| AU2012236150B2 (en) | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2012171443A1 (zh) * | 2011-06-13 | 2012-12-20 | 上海秀新臣邦医药科技有限公司 | 一种干粉给药装置 |
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2007
- 2007-12-21 CA CA2673553A patent/CA2673553C/en not_active Expired - Fee Related
- 2007-12-21 PL PL07857079T patent/PL2063940T3/pl unknown
- 2007-12-21 US US12/520,252 patent/US8567394B2/en not_active Expired - Fee Related
- 2007-12-21 WO PCT/EP2007/011372 patent/WO2008077623A1/en not_active Ceased
- 2007-12-21 BR BRPI0720846-4A patent/BRPI0720846A2/pt not_active IP Right Cessation
- 2007-12-21 EP EP07857079A patent/EP2063940B1/en not_active Not-in-force
- 2007-12-21 AU AU2007338305A patent/AU2007338305B2/en not_active Ceased
- 2007-12-21 RU RU2009126462/14A patent/RU2456027C2/ru not_active IP Right Cessation
- 2007-12-21 JP JP2009541914A patent/JP5564262B2/ja not_active Expired - Fee Related
- 2007-12-21 NZ NZ577764A patent/NZ577764A/en not_active IP Right Cessation
- 2007-12-21 SI SI200730901T patent/SI2063940T1/sl unknown
- 2007-12-21 CN CN2007800506647A patent/CN101600469B/zh not_active Expired - Fee Related
- 2007-12-21 AT AT07857079T patent/ATE540717T1/de active
- 2007-12-21 UA UAA200907632A patent/UA95506C2/uk unknown
- 2007-12-21 MY MYPI20092508A patent/MY148020A/en unknown
- 2007-12-21 KR KR1020097015097A patent/KR101392649B1/ko not_active Expired - Fee Related
- 2007-12-21 MX MX2009006787A patent/MX2009006787A/es active IP Right Grant
- 2007-12-21 ES ES07857079T patent/ES2378786T3/es active Active
- 2007-12-21 DK DK07857079.3T patent/DK2063940T3/da active
- 2007-12-21 PT PT07857079T patent/PT2063940E/pt unknown
- 2007-12-24 TW TW96149724A patent/TWI473630B/zh not_active IP Right Cessation
- 2007-12-24 CL CL2007003813A patent/CL2007003813A1/es unknown
- 2007-12-26 AR ARP070105908A patent/AR064540A1/es active IP Right Grant
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- 2008-01-02 PE PE2008000039A patent/PE20081674A1/es not_active Application Discontinuation
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- 2009-06-16 IL IL199380A patent/IL199380A/en not_active IP Right Cessation
- 2009-06-18 ZA ZA200904291A patent/ZA200904291B/xx unknown
- 2009-06-21 EG EG2009060945A patent/EG27057A/xx active
- 2009-06-22 EC EC2009009448A patent/ECSP099448A/es unknown
- 2009-07-16 NO NO20092686A patent/NO20092686L/no not_active Application Discontinuation
- 2009-07-22 CO CO09076099A patent/CO6220839A2/es active IP Right Grant
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- 2013-06-19 US US13/921,779 patent/US20140000602A1/en not_active Abandoned
- 2013-10-04 JP JP2013208856A patent/JP5740721B2/ja not_active Expired - Fee Related
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