PT1817282E - Derivados do ácido fenoxiacético úteis para tratar doenças respiratórias - Google Patents
Derivados do ácido fenoxiacético úteis para tratar doenças respiratórias Download PDFInfo
- Publication number
- PT1817282E PT1817282E PT05807437T PT05807437T PT1817282E PT 1817282 E PT1817282 E PT 1817282E PT 05807437 T PT05807437 T PT 05807437T PT 05807437 T PT05807437 T PT 05807437T PT 1817282 E PT1817282 E PT 1817282E
- Authority
- PT
- Portugal
- Prior art keywords
- methyl
- phenoxy
- piperazinyl
- acetic acid
- chloro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
- C07D213/34—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0425673A GB0425673D0 (en) | 2004-11-23 | 2004-11-23 | Novel compounds |
| GB0508923A GB0508923D0 (en) | 2005-04-30 | 2005-04-30 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1817282E true PT1817282E (pt) | 2011-09-19 |
Family
ID=35589515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT05807437T PT1817282E (pt) | 2004-11-23 | 2005-11-22 | Derivados do ácido fenoxiacético úteis para tratar doenças respiratórias |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8524715B2 (https=) |
| EP (1) | EP1817282B1 (https=) |
| JP (2) | JP5208510B2 (https=) |
| AR (1) | AR051966A1 (https=) |
| AT (1) | ATE517085T1 (https=) |
| CY (1) | CY1112115T1 (https=) |
| DK (1) | DK1817282T3 (https=) |
| PL (1) | PL1817282T3 (https=) |
| PT (1) | PT1817282E (https=) |
| SA (1) | SA05260362B1 (https=) |
| SI (1) | SI1817282T1 (https=) |
| TW (1) | TW200630336A (https=) |
| UY (1) | UY29223A1 (https=) |
| WO (1) | WO2006056752A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) * | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| JP5208510B2 (ja) | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| AU2006296004B2 (en) | 2005-09-27 | 2011-11-17 | Shionogi & Co., Ltd. | Sulfonamide derivative having PGD2 receptor antagonistic activity |
| EA015358B1 (ru) * | 2005-09-30 | 2011-06-30 | Пульмаджен Терапьютикс (Эсме) Лимитед | Хинолины и их терапевтическое применение |
| US8148572B2 (en) | 2005-10-06 | 2012-04-03 | Astrazeneca Ab | Compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| WO2007052023A2 (en) * | 2005-11-05 | 2007-05-10 | Astrazeneca Ab | Novel compounds |
| ATE545637T1 (de) * | 2005-12-15 | 2012-03-15 | Astrazeneca Ab | Substituierte diphenylether, -amine, -sulfide und methane zur behandlung von atemwegserkrankungen |
| UA100983C2 (ru) * | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| PT2229358E (pt) | 2007-12-14 | 2011-06-29 | Pulmagen Therapeutics Asthma Ltd | Indoles e sua utilização terapêutica |
| AU2009324679A1 (en) * | 2008-12-09 | 2011-07-28 | University Of Florida Research Foundation, Inc. | Kinase inhibitor compounds |
| EP2376435A2 (en) | 2009-01-14 | 2011-10-19 | Dow AgroSciences LLC | Synergistic fungicidal compositions including hydrazone derivatives and copper |
| EP2590944B1 (en) | 2010-07-05 | 2015-09-30 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| EP2790696A1 (en) | 2011-12-16 | 2014-10-22 | Atopix Therapeutics Limited | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| JP6097765B2 (ja) | 2011-12-21 | 2017-03-15 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | ヘテロシクリル誘導体及びプロスタグランジンｄ２受容体調節剤としてのそれらの使用 |
| WO2014006585A1 (en) | 2012-07-05 | 2014-01-09 | Actelion Pharmaceuticals Ltd | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| EP3288527B1 (en) | 2015-04-28 | 2020-02-19 | Unilever PLC, a company registered in England and Wales under company no. 41424 of | N-aralkylcarbonyldiamine compounds and personal care compositions comprising the same |
| US10155733B2 (en) | 2015-04-28 | 2018-12-18 | Conopco, Inc. | N-aralkylcarbonyl-piperazine and -homopiperazine compounds and personal care compositions comprising the same |
| WO2017209272A1 (ja) * | 2016-06-03 | 2017-12-07 | 国立大学法人東京大学 | がん転移阻害剤 |
| WO2020254559A1 (en) | 2019-06-19 | 2020-12-24 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB690816A (en) | 1950-01-02 | 1953-04-29 | British Drug Houses Ltd | Improvements in or relating to the manufacture of substituted phenoxy acetic acids |
| US3278524A (en) | 1962-03-13 | 1966-10-11 | Beecham Group Ltd | Penicillins and their production |
| CH432119A (de) | 1963-02-22 | 1967-03-15 | Geigy Ag J R | Verwendung von Halogen-o-hydroxy-diphenyläthern als antimikrobielle Mittel |
| BE790679A (fr) | 1971-11-03 | 1973-04-27 | Ici Ltd | Derives de l'indole |
| DD113545A5 (https=) | 1973-03-30 | 1975-06-12 | ||
| JPS5239888B2 (https=) | 1973-05-28 | 1977-10-07 | ||
| ES431425A1 (es) | 1973-10-29 | 1977-01-16 | Eisai Co Ltd | Un procedimiento para la preparacion de derivados del acido 2-(m-fenoxifenil)-propionico. |
| CH582476A5 (https=) | 1973-10-29 | 1976-12-15 | Ciba Geigy Ag | |
| GB1585963A (en) | 1976-10-14 | 1981-03-11 | Lilly Industries Ltd | Aryl sulphur compounds |
| US4248618A (en) | 1977-05-06 | 1981-02-03 | Ici Australia Limited | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof |
| FR2428629A1 (fr) | 1978-06-14 | 1980-01-11 | Hexachimie | Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique |
| JPS5951943B2 (ja) | 1978-08-21 | 1984-12-17 | キツセイ薬品工業株式会社 | 新規なイミダゾ−ル誘導体 |
| GB2041363B (en) | 1979-01-19 | 1982-10-06 | Pfizer Ltd | N-benzyl-imidazoles |
| US4670566A (en) | 1979-07-12 | 1987-06-02 | A. H. Robins Company, Incorporated | 3-methyl-hio-4-(5-, 6-, or 7-)phenylindolindolin-2-ones |
| US4486593A (en) | 1983-01-19 | 1984-12-04 | The Upjohn Company | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors |
| US5006542A (en) | 1988-10-31 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use |
| US5145790A (en) | 1990-05-04 | 1992-09-08 | Abbott Laboratories | Reagents and method for detecting polychlorinated biphenyls |
| EP0540165A1 (en) | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkanoic acid derivatives |
| WO1993012086A1 (fr) * | 1991-12-11 | 1993-06-24 | Ss Pharmaceutical Co., Ltd. | Derive d'arylamide |
| CA2090283A1 (en) | 1992-02-28 | 1993-08-29 | Nobuyuki Hamanaka | Phenoxyacetic acid derivatives |
| CA2110095A1 (en) * | 1992-12-08 | 1994-06-09 | Teruo Komoto | Arylamide derivatives |
| JP2825755B2 (ja) * | 1993-04-07 | 1998-11-18 | 大塚製薬株式会社 | ピペリジン誘導体を有効成分とする末梢血管拡張剤および新規ピペリジン誘導体 |
| JPH06313995A (ja) | 1993-04-28 | 1994-11-08 | Hodogaya Chem Co Ltd | 静電荷像現像用トナー |
| US5489412A (en) | 1993-04-30 | 1996-02-06 | Kabushiki Kaisha Meidensha | Electrode material |
| JPH07140725A (ja) | 1993-06-25 | 1995-06-02 | Hodogaya Chem Co Ltd | 負帯電性トナー用摩擦帯電付与部材 |
| US5612353A (en) * | 1995-06-07 | 1997-03-18 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
| EP0847379A1 (en) | 1995-08-28 | 1998-06-17 | American Home Products Corporation | Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents |
| ES2194209T3 (es) | 1996-07-22 | 2003-11-16 | Monsanto Co | Inhibidores de metaloproteasa de tiol sulfona. |
| CA2219269A1 (en) | 1996-10-29 | 1998-04-29 | Novartis Ag | Novel herbicides |
| FR2763588B1 (fr) | 1997-05-23 | 1999-07-09 | Cird Galderma | Composes triaromatiques, compositions les contenant et utilisations |
| CO4960662A1 (es) | 1997-08-28 | 2000-09-25 | Novartis Ag | Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados |
| US5942532A (en) | 1997-09-05 | 1999-08-24 | Ortho Pharmaceutical Corporation | 2-substituted phenyl-benzimidazole antibacterial agents |
| ES2226167T3 (es) | 1997-09-12 | 2005-03-16 | MERCK FROSST CANADA & CO. | Piridinas 2,3,5-sustituidas como inhibidores de ciclooxigenasa 2. |
| WO1999019291A1 (en) | 1997-10-14 | 1999-04-22 | Asahi Kasei Kogyo Kabushiki Kaisha | Biphenyl-5-alkanoic acid derivatives and use thereof |
| JP3486408B2 (ja) | 1999-08-23 | 2004-01-13 | 株式会社ビー・エム・エル | 物質のヒトプロスタグランジンｄ２受容体に対する性質の同定方法 |
| SE9902987D0 (sv) * | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
| DE60005973T2 (de) | 1999-08-27 | 2004-05-13 | Eli Lilly And Co., Indianapolis | Biaryl-oxa(thia)zolderivate und ihre verwendung als ppars modulatoren |
| AU784722B2 (en) | 2000-02-18 | 2006-06-01 | Merck & Co., Inc. | Aryloxyacetic acids for diabetes and lipid disorders |
| EP1278734A2 (en) | 2000-04-24 | 2003-01-29 | Merck Frosst Canada & Co. | Method of treatment using phenyl and biaryl derivatives as prostaglandin e inhibitors and compounds useful therefore |
| NZ522074A (en) | 2000-05-31 | 2004-06-25 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| JP2004501191A (ja) * | 2000-06-28 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | カルベジロール |
| US6878522B2 (en) | 2000-07-07 | 2005-04-12 | Baiyong Li | Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2 |
| US20040097555A1 (en) | 2000-12-26 | 2004-05-20 | Shinegori Ohkawa | Concomitant drugs |
| BR0210391A (pt) * | 2001-06-12 | 2004-06-15 | Elan Pharm Inc | Composto, métodos de tratar um paciente que tenha ou de prevenir um paciente de contrair uma doença ou condição e de preparar um composto, e, uso de um composto |
| CA2473803A1 (en) | 2002-02-01 | 2003-08-07 | Robert Greenhouse | Substituted indoles as alpha-1 agonists |
| SE0200411D0 (sv) | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| WO2003068744A1 (en) | 2002-02-18 | 2003-08-21 | Ishihara Sangyo Kaisha, Ltd. | Pyridine derivatives or salts thereof and cytokine production inhibitors containing the same |
| CA2479338A1 (en) | 2002-03-20 | 2003-10-02 | Metabolex, Inc. | Substituted phenylacetic acids |
| AU2003231513A1 (en) | 2002-05-16 | 2003-12-02 | Shionogi And Co., Ltd. | Pgd2 receptor antagonist |
| EP2423190A1 (en) | 2002-05-16 | 2012-02-29 | Shionogi&Co., Ltd. | Compounds Exhibiting PGD 2 Receptor Antagonism |
| SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
| SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
| US7119200B2 (en) * | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| PE20040844A1 (es) | 2002-11-26 | 2004-12-30 | Novartis Ag | Acidos fenilaceticos y derivados como inhibidores de la cox-2 |
| WO2004052862A1 (ja) * | 2002-12-10 | 2004-06-24 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびその医薬用途 |
| ZA200505523B (en) | 2002-12-20 | 2006-09-27 | Amgen Inc | Asthma and allergic inflammation modulators |
| US7414063B2 (en) | 2003-03-28 | 2008-08-19 | Eli Lilly And Company | Inhibitors of Akt (protein kinase B) |
| JP2004315511A (ja) * | 2003-03-31 | 2004-11-11 | Taisho Pharmaceut Co Ltd | Ｍｃｈ受容体アンタゴニスト |
| SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SE0301009D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| DE60303238T2 (de) | 2003-04-25 | 2006-09-14 | Actimis Pharmaceuticals, Inc., La Jolla | Pyrimidin-Essigsäure Derivate geeignet zur Behandlung von CRTH2-bedingten Krankheiten |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
| US7166738B2 (en) | 2004-04-23 | 2007-01-23 | Roche Palo Alto Llc | Non-nucleoside reverse transcriptase inhibitors |
| GB0409921D0 (en) | 2004-05-04 | 2004-06-09 | Novartis Ag | Organic compounds |
| BRPI0511676A (pt) * | 2004-05-29 | 2008-01-08 | 7Tm Pharma As | uso medicinal de ligandos receptores |
| GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| JP5208510B2 (ja) * | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| GB0510584D0 (en) | 2005-05-24 | 2005-06-29 | Novartis Ag | Organic compounds |
| US8148572B2 (en) | 2005-10-06 | 2012-04-03 | Astrazeneca Ab | Compounds |
| TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| WO2007052023A2 (en) | 2005-11-05 | 2007-05-10 | Astrazeneca Ab | Novel compounds |
| ATE545637T1 (de) | 2005-12-15 | 2012-03-15 | Astrazeneca Ab | Substituierte diphenylether, -amine, -sulfide und methane zur behandlung von atemwegserkrankungen |
| UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
-
2005
- 2005-11-22 JP JP2007542103A patent/JP5208510B2/ja not_active Expired - Fee Related
- 2005-11-22 US US11/719,832 patent/US8524715B2/en not_active Expired - Fee Related
- 2005-11-22 AR ARP050104896A patent/AR051966A1/es unknown
- 2005-11-22 DK DK05807437.8T patent/DK1817282T3/da active
- 2005-11-22 AT AT05807437T patent/ATE517085T1/de active
- 2005-11-22 PL PL05807437T patent/PL1817282T3/pl unknown
- 2005-11-22 EP EP05807437A patent/EP1817282B1/en not_active Expired - Lifetime
- 2005-11-22 SI SI200531361T patent/SI1817282T1/sl unknown
- 2005-11-22 UY UY29223A patent/UY29223A1/es not_active Application Discontinuation
- 2005-11-22 WO PCT/GB2005/004464 patent/WO2006056752A1/en not_active Ceased
- 2005-11-22 PT PT05807437T patent/PT1817282E/pt unknown
- 2005-11-23 TW TW094141046A patent/TW200630336A/zh unknown
- 2005-11-23 SA SA05260362A patent/SA05260362B1/ar unknown
-
2011
- 2011-09-15 CY CY20111100891T patent/CY1112115T1/el unknown
-
2012
- 2012-12-21 JP JP2012280027A patent/JP2013082729A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013082729A (ja) | 2013-05-09 |
| EP1817282A1 (en) | 2007-08-15 |
| JP2008520637A (ja) | 2008-06-19 |
| WO2006056752A1 (en) | 2006-06-01 |
| TW200630336A (en) | 2006-09-01 |
| UY29223A1 (es) | 2006-06-30 |
| AR051966A1 (es) | 2007-02-21 |
| SA05260362B1 (ar) | 2009-04-18 |
| JP5208510B2 (ja) | 2013-06-12 |
| EP1817282B1 (en) | 2011-07-20 |
| US20090149448A1 (en) | 2009-06-11 |
| US8524715B2 (en) | 2013-09-03 |
| DK1817282T3 (da) | 2011-10-10 |
| SI1817282T1 (sl) | 2011-10-28 |
| ATE517085T1 (de) | 2011-08-15 |
| PL1817282T3 (pl) | 2011-11-30 |
| CY1112115T1 (el) | 2015-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1817282E (pt) | Derivados do ácido fenoxiacético úteis para tratar doenças respiratórias | |
| ES2314389T3 (es) | Derivados de acido fenoxiacetico para tratar trastornos respiratorios. | |
| AU2008272690B2 (en) | Novel compounds 951: a biphenyloxypropanoic acid as CRTH2 modulator and intermediates | |
| ES2335425T3 (es) | Derivados de acido bifeniloxiacetico para el tratamiento de enfermedades respiratorias. | |
| RU2456286C2 (ru) | Хинуклидиновые производные (гетеро)арилциклогептанкарбоновой кислоты в качестве антагонистов мускариновых рецепторов | |
| JP4604129B2 (ja) | ムスカリン受容体アンタゴニストとしてのキヌクリジノール誘導体 | |
| RU2509077C2 (ru) | Феноксипиридиниламидные производные и их применение в лечении pde4-опосредованных болезненных состояний | |
| US20080255150A1 (en) | Novel Compounds | |
| BRPI0813244B1 (pt) | Compostos derivados de pirazinona, composições compreendendo ditos compostos, uso dos compostos no tratamento de doenças de pulmão e composto intermediário | |
| BRPI0711362A2 (pt) | derivados de 2-pirazinona, processo para sua preparação,uso relacionado,composição farmacêutica compreendendo os mesmos e processo para a preparação da referida composição farmacêutica | |
| PT1937633E (pt) | Derivados do ácido bifenilacético para o tratamento da doença respiratória | |
| MX2008001664A (es) | Derivados novedosos de benzotiazolona. | |
| CN101679275B (zh) | 异喹诺酮衍生物及其药学上的应用 | |
| JP2008538762A (ja) | 新規ムスカリン受容体アンタゴニスト | |
| ES2368070T3 (es) | Derivados del ácido fenoxiacético de utilidad en el tratamiento de enfermedades respiratorias. | |
| WO2008136754A1 (en) | Novel benzyl - 2 -oxo-piperazinyl/ 7-oxo/5-oxa- [1,4] diazepanyl/ 2 -oxo- tetrahydropyrimidinyl derivatives | |
| BRPI0613563A2 (pt) | novos derivados de piperidina | |
| US20090118288A1 (en) | N-Benzyl-Morpholine Derivatives as Modulators of the Chemokine Receptor | |
| WO2010018352A1 (en) | Heterocyclic compounds used in the treatment of diseases where enhanced m3 receptor activation is implicated | |
| CN101356164A (zh) | 新颖化合物 | |
| JP2011195593A (ja) | ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体 |