PT1697326E - Forma cristalina de composto quinolínico e processo para a sua produção - Google Patents

Forma cristalina de composto quinolínico e processo para a sua produção Download PDF

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Publication number
PT1697326E
PT1697326E PT04807807T PT04807807T PT1697326E PT 1697326 E PT1697326 E PT 1697326E PT 04807807 T PT04807807 T PT 04807807T PT 04807807 T PT04807807 T PT 04807807T PT 1697326 E PT1697326 E PT 1697326E
Authority
PT
Portugal
Prior art keywords
crystal form
production
quinoline compound
stability
drug substance
Prior art date
Application number
PT04807807T
Other languages
English (en)
Inventor
Yoshio Ohara
Yasutaka Takada
Hiroo Matsumoto
Akihiro Yoshida
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34736450&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1697326(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of PT1697326E publication Critical patent/PT1697326E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT04807807T 2003-12-26 2004-12-17 Forma cristalina de composto quinolínico e processo para a sua produção PT1697326E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003431788 2003-12-26

Publications (1)

Publication Number Publication Date
PT1697326E true PT1697326E (pt) 2011-09-12

Family

ID=34736450

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04807807T PT1697326E (pt) 2003-12-26 2004-12-17 Forma cristalina de composto quinolínico e processo para a sua produção

Country Status (22)

Country Link
US (19) US20070112024A1 (pt)
EP (1) EP1697326B1 (pt)
JP (7) JP5186108B2 (pt)
KR (11) KR20170098976A (pt)
CN (2) CN1898211A (pt)
AT (1) ATE518835T1 (pt)
AU (2) AU2004309241A1 (pt)
CA (1) CA2551050C (pt)
CY (1) CY1112464T1 (pt)
DK (1) DK1697326T3 (pt)
ES (1) ES2367172T3 (pt)
HK (1) HK1095328A1 (pt)
IL (1) IL176470A (pt)
MX (1) MX338019B (pt)
NZ (1) NZ548041A (pt)
PL (1) PL1697326T3 (pt)
PT (1) PT1697326E (pt)
RU (1) RU2370489C2 (pt)
SI (1) SI1697326T1 (pt)
TW (1) TWI328006B (pt)
WO (1) WO2005063711A1 (pt)
ZA (1) ZA200605658B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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WO2004072040A1 (en) 2003-02-12 2004-08-26 Ciba Specialty Chemicals Holding Inc. Crystalline forms of pitavastatin calcium
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
US7801272B2 (en) * 2007-09-28 2010-09-21 Rigaku Corporation X-ray diffraction apparatus and X-ray diffraction method
WO2011089623A2 (en) * 2010-01-20 2011-07-28 Cadila Healthcare Limited Process for preparing pitavastatin and pharmaceutically acceptable salts thereof
KR101158517B1 (ko) 2010-04-29 2012-06-21 동방에프티엘(주) 고 순도 피타바스타틴 칼슘염 결정형 ａ의 제조방법
WO2012025939A1 (en) 2010-08-25 2012-03-01 Cadila Healthcare Limited Pitavastatin calcium and process for its preparation
EP3178812A1 (en) 2010-11-12 2017-06-14 Hetero Research Foundation Novel polymorphs of pitavastatin calcium
RU2452939C1 (ru) * 2011-01-18 2012-06-10 Закрытое акционерное общество "Научные приборы" Рентгенодифракционный способ идентификации партий фармацевтической продукции
ITMI20111475A1 (it) * 2011-08-02 2013-02-03 Dipharma Francis Srl Forme cristalline di pitavastatina sale di calcio
EP2751081B1 (en) 2011-09-12 2017-01-04 Farma GRS, d.o.o. Polymorphic form of pitavastatin calcium
WO2013098773A1 (en) * 2011-12-28 2013-07-04 Dr. Reddy's Laboratories Limited Crystalline forms of pitavastatin calcium
EP3124017A1 (en) 2012-08-08 2017-02-01 Kowa Company, Ltd. Pharmaceutical composition comprising pitavastatine
US9464095B2 (en) * 2012-09-27 2016-10-11 Nissan Chemical Industries, Ltd. Production method of high-purity nitrogen-containing heterocyclic compound
JP2014034574A (ja) * 2013-01-25 2014-02-24 Kowa Company Ltd 医薬
CN105228984B (zh) * 2013-03-15 2018-03-23 爱西里斯药物技术有限公司 硝羟喹啉碱加成盐及其用途
CN105213319A (zh) * 2015-09-17 2016-01-06 青岛华之草医药科技有限公司 一种降血脂药物匹伐他汀钙组合物干混悬剂
JP2016222714A (ja) * 2016-09-20 2016-12-28 興和株式会社 医薬
TW202200547A (zh) * 2020-03-13 2022-01-01 印度商卡地拉保健有限公司 喹啉酮化合物的新穎鹽類
CN116997331A (zh) * 2021-03-19 2023-11-03 兹杜斯生命科学有限公司 固体形式的喹诺酮化合物及其制备方法

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IL63968A (en) 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
JPS61171460A (ja) * 1985-01-23 1986-08-02 Dainippon Pharmaceut Co Ltd 塩酸メクロフエノキサ−ト１型結晶の製造法
JP2569746B2 (ja) * 1987-08-20 1997-01-08 日産化学工業株式会社 キノリン系メバロノラクトン類
JP2877366B2 (ja) 1988-08-25 1999-03-31 協和醗酵工業株式会社 結晶状ｌ−アスコルビン酸−２−リン酸ナトリウム塩の製造法
JP3528186B2 (ja) * 1991-06-24 2004-05-17 日産化学工業株式会社 光学活性キノリンメバロン酸のジアステレオマー塩
JPH0613526A (ja) 1992-06-25 1994-01-21 Seiko Epson Corp 半導体装置用リードフレーム及びその製造方法
JP2575590B2 (ja) * 1992-07-31 1997-01-29 塩野義製薬株式会社 トリアゾリルチオメチルチオセファロスポリン塩酸塩およびその水和物結晶ならびにそれらの製法
FR2694558B1 (fr) 1992-08-05 1994-10-28 Sanofi Elf Monohydrate du sel disodique de l'acide 4-chlorophénylthiométhylène bisphosphonique, sa préparation, les compositions pharmaceutiques en contenant.
DE4235133A1 (de) 1992-10-19 1994-04-21 Bayer Ag Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid
JP3623531B2 (ja) 1993-06-07 2005-02-23 ビーエーエスエフ アクチェンゲゼルシャフト 結晶質ｌ−アスコルビン酸−２−燐酸エステルマグネシウム塩の製造法
JP3558684B2 (ja) * 1994-06-28 2004-08-25 塩野義製薬株式会社 ピロリジルチオカルバペネム誘導体の乾燥方法
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US6869970B2 (en) * 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
WO2003087091A1 (fr) * 2002-04-17 2003-10-23 Yamanouchi Pharmaceutical Co., Ltd. Nouveau cristal d'anhydride de derive de quinoxalinedione
WO2004072040A1 (en) * 2003-02-12 2004-08-26 Ciba Specialty Chemicals Holding Inc. Crystalline forms of pitavastatin calcium
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production

Also Published As

Publication number Publication date
ZA200605658B (en) 2007-11-28
ES2367172T3 (es) 2011-10-31
CN102321019B (zh) 2016-06-08
MX338019B (es) 2016-03-29
JP2014205719A (ja) 2014-10-30
US20120245200A1 (en) 2012-09-27
US20070112024A1 (en) 2007-05-17
JP2018052988A (ja) 2018-04-05
ATE518835T1 (de) 2011-08-15
CY1112464T1 (el) 2015-12-09
KR20170010111A (ko) 2017-01-25
DK1697326T3 (da) 2011-09-19
JP2013136640A (ja) 2013-07-11
AU2011213742A1 (en) 2011-09-08
JP2017061536A (ja) 2017-03-30
US20170226061A1 (en) 2017-08-10
JP2012072175A (ja) 2012-04-12
KR20180132973A (ko) 2018-12-12
PL1697326T3 (pl) 2011-12-30
US20230322679A1 (en) 2023-10-12
US20200216395A1 (en) 2020-07-09
KR20180040732A (ko) 2018-04-20
SI1697326T1 (sl) 2011-11-30
KR20070001910A (ko) 2007-01-04
CA2551050A1 (en) 2005-07-14
US20180072676A1 (en) 2018-03-15
JP5267643B2 (ja) 2013-08-21
NZ548041A (en) 2010-04-30
US20180297956A1 (en) 2018-10-18
US20140058109A1 (en) 2014-02-27
US20220177433A1 (en) 2022-06-09
US20210053923A1 (en) 2021-02-25
US20130204000A1 (en) 2013-08-08
KR20170098976A (ko) 2017-08-30
US20140206719A1 (en) 2014-07-24
WO2005063711A1 (en) 2005-07-14
CA2551050C (en) 2020-06-02
AU2011213742B2 (en) 2014-05-15
US20190152916A1 (en) 2019-05-23
CN102321019A (zh) 2012-01-18
US20090176987A1 (en) 2009-07-09
JP2007516952A (ja) 2007-06-28
CN1898211A (zh) 2007-01-17
RU2006127044A (ru) 2008-02-10
JP5186108B2 (ja) 2013-04-17
KR20130014643A (ko) 2013-02-07
HK1095328A1 (en) 2007-05-04
AU2011213742C1 (en) 2017-04-06
IL176470A (en) 2011-10-31
IL176470A0 (en) 2006-10-05
RU2370489C2 (ru) 2009-10-20
EP1697326A1 (en) 2006-09-06
EP1697326B1 (en) 2011-08-03
TWI328006B (en) 2010-08-01
AU2004309241A1 (en) 2005-07-14
US20240294476A1 (en) 2024-09-05
KR20160075844A (ko) 2016-06-29
KR20110017936A (ko) 2011-02-22
KR20190083674A (ko) 2019-07-12
KR20200015826A (ko) 2020-02-12
US20110319624A1 (en) 2011-12-29
KR20200130510A (ko) 2020-11-18
JP2016029102A (ja) 2016-03-03
US20110082298A1 (en) 2011-04-07
US20150158816A1 (en) 2015-06-11
TW200530186A (en) 2005-09-16
US20190367458A1 (en) 2019-12-05

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