PT1640381E - Fator de crescimento neurotrófico - Google Patents

Fator de crescimento neurotrófico Download PDF

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Publication number
PT1640381E
PT1640381E PT51124733T PT05112473T PT1640381E PT 1640381 E PT1640381 E PT 1640381E PT 51124733 T PT51124733 T PT 51124733T PT 05112473 T PT05112473 T PT 05112473T PT 1640381 E PT1640381 E PT 1640381E
Authority
PT
Portugal
Prior art keywords
growth factor
neurotrophic growth
bioprecursor
organism
derivative
Prior art date
Application number
PT51124733T
Other languages
English (en)
Inventor
Theo Frans Meert
Stefan Leo Jozef Masure
Miroslav Cik
Hugo Alfons Gabriel Geerts
Luc Ver Donck
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1640381(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9815283.8A external-priority patent/GB9815283D0/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT1640381E publication Critical patent/PT1640381E/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Psychology (AREA)
  • General Physics & Mathematics (AREA)
PT51124733T 1998-07-14 1999-07-14 Fator de crescimento neurotrófico PT1640381E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9815283.8A GB9815283D0 (en) 1998-07-14 1998-07-14 Neurotrophic growth factor
US24877299A 1999-02-12 1999-02-12
US32766899A 1999-06-08 1999-06-08

Publications (1)

Publication Number Publication Date
PT1640381E true PT1640381E (pt) 2014-07-17

Family

ID=27269394

Family Applications (2)

Application Number Title Priority Date Filing Date
PT51124733T PT1640381E (pt) 1998-07-14 1999-07-14 Fator de crescimento neurotrófico
PT99938261T PT1097167E (pt) 1998-07-14 1999-07-14 Factor de crescimento neurotrofico

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT99938261T PT1097167E (pt) 1998-07-14 1999-07-14 Factor de crescimento neurotrofico

Country Status (28)

Country Link
US (1) US7544788B2 (pt)
EP (2) EP1640381B1 (pt)
JP (2) JP4469500B2 (pt)
KR (2) KR100712223B1 (pt)
CN (1) CN1243770C (pt)
AT (1) ATE343594T1 (pt)
AU (1) AU768472B2 (pt)
BG (1) BG65518B1 (pt)
BR (2) BR9912819A (pt)
CA (1) CA2333910C (pt)
CY (2) CY1105949T1 (pt)
CZ (1) CZ303868B6 (pt)
DE (1) DE69933771T2 (pt)
DK (2) DK1640381T3 (pt)
ES (2) ES2479067T3 (pt)
HK (2) HK1045528B (pt)
HR (1) HRP20010036B1 (pt)
HU (1) HU226073B1 (pt)
ID (1) ID27024A (pt)
IL (1) IL140877A0 (pt)
NO (1) NO331809B1 (pt)
NZ (1) NZ509723A (pt)
PL (1) PL209952B1 (pt)
PT (2) PT1640381E (pt)
SI (1) SI1640381T1 (pt)
SK (1) SK287361B6 (pt)
TR (1) TR200100074T2 (pt)
WO (1) WO2000004050A2 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593133B1 (en) * 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
CZ303358B6 (cs) * 1998-07-06 2012-08-15 Nsgene A/S Neurotrofní polypeptid, zpusob jeho výroby a použití, kódující polynukleotid, príslušný vektor a hostitelská bunka, syntetický gen a protilátka
US7067473B1 (en) * 1998-07-14 2006-06-27 Janssen Pharmaceutica N.V. Neurotrophic growth factor
DK1640381T3 (da) * 1998-07-14 2014-07-14 Janssen Pharmaceutica Nv Neurotrofisk vækstfaktor
US20020002269A1 (en) 1998-09-29 2002-01-03 Jeffrey D. Milbrandt Artemin, a neurotrophic factor
JP2002531128A (ja) * 1998-12-09 2002-09-24 アムジエン・インコーポレーテツド 神経栄養因子ｇｒｎｆ４
EP1867719A3 (en) * 1999-06-02 2008-03-19 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
EP1423139A2 (en) * 2000-12-22 2004-06-02 Genentech, Inc. New use of artemin, a member of the gdnf ligand family
US7442370B2 (en) 2001-02-01 2008-10-28 Biogen Idec Ma Inc. Polymer conjugates of mutated neublastin
US7276580B2 (en) * 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
US20040077543A1 (en) * 2001-03-28 2004-04-22 Sah Dinah W. Y. Treatment using neublastin polypeptides
JP4499362B2 (ja) * 2001-03-28 2010-07-07 バイオジェン・アイデック・エムエイ・インコーポレイテッド ニューロパシーの疼痛を処置するためのニューブラスチンポリペプチドの使用
AU2003242527B2 (en) * 2002-05-17 2008-10-23 Tioga Pharmaceuticals, Inc. Use of compounds that are effective as selective opiate receptor modulators
JP4571776B2 (ja) * 2002-11-05 2010-10-27 Ｊｘ日鉱日石エネルギー株式会社 潤滑油組成物
CA2864810A1 (en) 2003-04-18 2004-11-04 Biogen Idec Ma, Inc. Polymer-conjugated glycosylated neublastin
ES2353457T3 (es) 2003-06-10 2011-03-02 Nsgene A/S Secreción mejorada de neublastina.
US7598059B2 (en) 2003-10-02 2009-10-06 Biogen Idec Ma Inc. Neublastin expression constructs
NZ553420A (en) 2004-08-19 2010-02-26 Biogen Idec Inc Refolding transforming growth factor beta family proteins
EP2238983B1 (en) * 2004-08-19 2014-07-23 Biogen Idec MA Inc. Neublastin variants
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
ES2450065T3 (es) * 2006-03-01 2014-03-21 Biogen Idec Ma Inc. Composiciones y métodos para la administración de proteínas de la familia de ligandos del GDNF
NZ579050A (en) 2007-02-06 2012-10-26 Tai June Yoo Treatment and prevention of neurodegenerative diseases using gene therapy
US8329655B2 (en) * 2007-05-01 2012-12-11 Biogen Idec Ma Inc. Methods for increasing vascularization
EP2164870B1 (en) * 2007-06-27 2015-12-09 National University of Singapore Polypeptides and polynucleotides for artemin and related ligands, and methods of use thereof
WO2009020964A2 (en) * 2007-08-08 2009-02-12 Biogen Idec Ma Inc. Anti-neublastin antibodies and uses thereof
JO3462B1 (ar) * 2012-08-22 2020-07-05 Regeneron Pharma أجسام مضادة بشرية تجاه gfr?3 وطرق لاستخدامها
US11225689B2 (en) * 2016-08-17 2022-01-18 The Broad Institute, Inc. Method for determination and identification of cell signatures and cell markers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5739307A (en) * 1995-08-28 1998-04-14 Washington University Polynucleotide encoding neurturin neurotrophic factor
US5972338A (en) * 1997-09-19 1999-10-26 Genentech, Inc. Tie ligands homologues
US6593133B1 (en) * 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
US20020055467A1 (en) * 1998-07-06 2002-05-09 Johansen Teit E. Novel neurotrophic factors
DK1640381T3 (da) * 1998-07-14 2014-07-14 Janssen Pharmaceutica Nv Neurotrofisk vækstfaktor
US7067473B1 (en) * 1998-07-14 2006-06-27 Janssen Pharmaceutica N.V. Neurotrophic growth factor
US20020002269A1 (en) * 1998-09-29 2002-01-03 Jeffrey D. Milbrandt Artemin, a neurotrophic factor
JP2002531128A (ja) † 1998-12-09 2002-09-24 アムジエン・インコーポレーテツド 神経栄養因子ｇｒｎｆ４
JP2002051906A (ja) * 2000-08-11 2002-02-19 Nippon Platec Co Ltd Ｉｈ調理器による加熱を可能にしたアルミ箔材料及びこのアルミ箔材料を用いて成形したアルミ箔材料製食品用容器
US7276580B2 (en) * 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
WO2018191688A2 (en) † 2017-04-14 2018-10-18 Johnson Controls Techology Company Thermostat with exhaust fan control for air quality and humidity control

Also Published As

Publication number Publication date
JP2002520042A (ja) 2002-07-09
DE69933771D1 (de) 2006-12-07
HK1045528A1 (en) 2002-11-29
KR20010083108A (ko) 2001-08-31
NZ509723A (en) 2004-01-30
WO2000004050A3 (en) 2000-11-09
TR200100074T2 (tr) 2001-11-21
SK287361B6 (sk) 2010-08-09
CA2333910A1 (en) 2000-01-27
JP4624476B2 (ja) 2011-02-02
EP1097167B1 (en) 2006-10-25
CY1115496T1 (el) 2017-01-04
DE69933771T2 (de) 2007-09-13
CZ200128A3 (cs) 2001-08-15
HK1092477A1 (en) 2007-02-09
CN1342165A (zh) 2002-03-27
EP1640381B1 (en) 2014-05-14
NO20010212L (no) 2001-03-14
SK142001A3 (en) 2002-02-05
JP2010158241A (ja) 2010-07-22
PL348431A1 (en) 2002-05-20
HRP20010036A2 (en) 2001-12-31
BG105107A (en) 2001-10-31
AU5283299A (en) 2000-02-07
CA2333910C (en) 2016-11-15
EP1097167B2 (en) 2018-12-12
ES2275349T3 (es) 2007-06-01
IL140877A0 (en) 2002-02-10
NO20010212D0 (no) 2001-01-12
PT1097167E (pt) 2007-02-28
HUP0102821A2 (hu) 2001-11-28
NO331809B1 (no) 2012-04-10
KR100773776B1 (ko) 2007-11-12
US20050233359A1 (en) 2005-10-20
EP1640381A3 (en) 2007-01-31
HUP0102821A3 (en) 2003-09-29
EP1640381A2 (en) 2006-03-29
CZ303868B6 (cs) 2013-06-05
DK1097167T3 (da) 2007-03-12
BRPI9912819B1 (pt) 2018-09-18
ATE343594T1 (de) 2006-11-15
BRPI9912819B8 (pt) 2021-05-25
DK1640381T3 (da) 2014-07-14
AU768472B2 (en) 2003-12-11
HRP20010036B1 (en) 2010-06-30
CY1105949T1 (el) 2011-04-06
WO2000004050A2 (en) 2000-01-27
JP4469500B2 (ja) 2010-05-26
CN1243770C (zh) 2006-03-01
EP1097167A2 (en) 2001-05-09
US7544788B2 (en) 2009-06-09
BG65518B1 (bg) 2008-10-31
ID27024A (id) 2001-02-22
PL209952B1 (pl) 2011-11-30
ES2479067T3 (es) 2014-07-23
BR9912819A (pt) 2001-05-02
KR100712223B1 (ko) 2007-04-27
KR20060061408A (ko) 2006-06-07
SI1640381T1 (sl) 2014-07-31
HU226073B1 (en) 2008-04-28
HK1045528B (zh) 2006-10-27

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