DE69933771D1 - Neurotrophischer wachstumsfaktor - Google Patents
Neurotrophischer wachstumsfaktorInfo
- Publication number
- DE69933771D1 DE69933771D1 DE69933771T DE69933771T DE69933771D1 DE 69933771 D1 DE69933771 D1 DE 69933771D1 DE 69933771 T DE69933771 T DE 69933771T DE 69933771 T DE69933771 T DE 69933771T DE 69933771 D1 DE69933771 D1 DE 69933771D1
- Authority
- DE
- Germany
- Prior art keywords
- growth factor
- neurotrophic growth
- bioprecursor
- organism
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003102 growth factor Substances 0.000 title abstract 4
- 230000000508 neurotrophic effect Effects 0.000 title abstract 2
- 102100026376 Artemin Human genes 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 108010059258 enovin Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Psychology (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9815283.8A GB9815283D0 (en) | 1998-07-14 | 1998-07-14 | Neurotrophic growth factor |
GB9815283 | 1998-07-14 | ||
US24877299A | 1999-02-12 | 1999-02-12 | |
US248772 | 1999-02-12 | ||
US32766899A | 1999-06-08 | 1999-06-08 | |
US327668 | 1999-06-08 | ||
PCT/EP1999/005031 WO2000004050A2 (en) | 1998-07-14 | 1999-07-14 | Neurotrophic growth factor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69933771D1 true DE69933771D1 (de) | 2006-12-07 |
DE69933771T2 DE69933771T2 (de) | 2007-09-13 |
Family
ID=27269394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69933771T Expired - Lifetime DE69933771T2 (de) | 1998-07-14 | 1999-07-14 | Neurotrophischer wachstumsfaktor |
Country Status (28)
Country | Link |
---|---|
US (1) | US7544788B2 (de) |
EP (2) | EP1097167B2 (de) |
JP (2) | JP4469500B2 (de) |
KR (2) | KR100773776B1 (de) |
CN (1) | CN1243770C (de) |
AT (1) | ATE343594T1 (de) |
AU (1) | AU768472B2 (de) |
BG (1) | BG65518B1 (de) |
BR (2) | BRPI9912819B8 (de) |
CA (1) | CA2333910C (de) |
CY (2) | CY1105949T1 (de) |
CZ (1) | CZ303868B6 (de) |
DE (1) | DE69933771T2 (de) |
DK (2) | DK1640381T3 (de) |
ES (2) | ES2479067T3 (de) |
HK (2) | HK1045528B (de) |
HR (1) | HRP20010036B1 (de) |
HU (1) | HU226073B1 (de) |
ID (1) | ID27024A (de) |
IL (1) | IL140877A0 (de) |
NO (1) | NO331809B1 (de) |
NZ (1) | NZ509723A (de) |
PL (1) | PL209952B1 (de) |
PT (2) | PT1640381E (de) |
SI (1) | SI1640381T1 (de) |
SK (1) | SK287361B6 (de) |
TR (1) | TR200100074T2 (de) |
WO (1) | WO2000004050A2 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6593133B1 (en) | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
BR9911908A (pt) * | 1998-07-06 | 2001-03-27 | Nsgene As | ácido nucléico, sequência de ácido nucléico, processos de usar um ácido nucléico, de usar o vetor, de fabricar o polipeptìdeo, de administrar o polipeptìdeo, de tratar uma doença ou distúrbio neurodegenerativos em um animal, de determinar se uma doença ou distúrbio neurodegenerativos em um animal, de produzir qualquer um polipeptìdeo, processo para identificar, isolar ou amplificar uma sequência de ácido nucléico de neublastina, de diagnosticar ou avaliar quanto a presença de uma doença ou distúrbio ou uma predisposiçãopara desnvolvê-los, para avaliar um polipeptìdeo de neublastina purificado ou um derivado ou fragmento deste ou um modulador da atividade dos precedentes quanto a atividade em tratar ou prevenir uma doença, de tratar um distúbio neurológico, de usar a sequência de um ou mais ácidos nucléicos, e para identificar um composto candidato que induza um efeito biológico mediado pela neuroblastina, vetor, célula transformada com ácido nucléico, polipeptìdeo, cmposição, anticorpo, gene sintético, e, conjunto. |
US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
SI1640381T1 (sl) * | 1998-07-14 | 2014-07-31 | Janssen Pharmaceutica Nv | Nevrotropski rastni faktor |
US20020002269A1 (en) * | 1998-09-29 | 2002-01-03 | Jeffrey D. Milbrandt | Artemin, a neurotrophic factor |
AU2354600A (en) * | 1998-12-09 | 2000-06-26 | Amgen, Inc. | Grnf4 a neurotrophic factor |
EP1820860A3 (de) * | 1999-06-02 | 2008-03-19 | Genentech, Inc. | Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums |
IL156559A0 (en) * | 2000-12-22 | 2004-01-04 | Genentech Inc | New use of artemin, a member of the gdnf ligand family |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
NZ529126A (en) * | 2001-03-28 | 2010-07-30 | Biogen Idec Inc | Use of neublastin polypeptides for treating allodynia, hyperalgesic pain and phantom pain |
US20040077543A1 (en) * | 2001-03-28 | 2004-04-22 | Sah Dinah W. Y. | Treatment using neublastin polypeptides |
JP2005531557A (ja) * | 2002-05-17 | 2005-10-20 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 選択的オピエート受容体モジュレーターとして効果的な化合物の使用 |
JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
EP1897552B1 (de) | 2003-04-18 | 2009-06-17 | Biogen Idec MA Inc. | Polymerkonjugiertes glycosiliertes Neublastin |
EP2058329B1 (de) | 2003-06-10 | 2010-08-18 | NsGene A/S | Verbesserte Sekretion von Neublastin |
US7598059B2 (en) | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
CN102924585A (zh) * | 2004-08-19 | 2013-02-13 | 比奥根艾迪克Ma公司 | 神经胚素变体 |
WO2006023782A2 (en) | 2004-08-19 | 2006-03-02 | Biogen Ideca Ma Inc. | Refolding transforming growth factor beta family proteins |
TWI501774B (zh) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
EP1993590B1 (de) * | 2006-03-01 | 2013-12-25 | Biogen Idec MA Inc. | Zusammensetzungen und verfahren zur verabreichung von proteinen der gdnf-liganden-familie |
AU2008213999B2 (en) | 2007-02-06 | 2014-04-17 | Tai June Yoo | Treatment and prevention of neurodegenerative diseases using gene therapy |
ES2476253T3 (es) | 2007-05-01 | 2014-07-14 | Biogen Idec Ma Inc. | P�ptidos de neublastina para su uso en el aumento de la vascularizaci�n en tejido con flujo sanguíneo deteriorado |
AU2008269689A1 (en) * | 2007-06-27 | 2008-12-31 | Auckland Uniservices Limited | Polypeptides and polynucleotides for artemin and related ligands, and methods of use thereof |
EP2205634A2 (de) * | 2007-08-08 | 2010-07-14 | Biogen Idec MA, Inc. | Anti-neublastin-antikörper und anwendungen davon |
JO3462B1 (ar) * | 2012-08-22 | 2020-07-05 | Regeneron Pharma | أجسام مضادة بشرية تجاه gfr?3 وطرق لاستخدامها |
US11225689B2 (en) * | 2016-08-17 | 2022-01-18 | The Broad Institute, Inc. | Method for determination and identification of cell signatures and cell markers |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
US5739307A (en) * | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
US5972338A (en) * | 1997-09-19 | 1999-10-26 | Genentech, Inc. | Tie ligands homologues |
US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US20020055467A1 (en) * | 1998-07-06 | 2002-05-09 | Johansen Teit E. | Novel neurotrophic factors |
US7067473B1 (en) * | 1998-07-14 | 2006-06-27 | Janssen Pharmaceutica N.V. | Neurotrophic growth factor |
SI1640381T1 (sl) * | 1998-07-14 | 2014-07-31 | Janssen Pharmaceutica Nv | Nevrotropski rastni faktor |
US20020002269A1 (en) * | 1998-09-29 | 2002-01-03 | Jeffrey D. Milbrandt | Artemin, a neurotrophic factor |
AU2354600A (en) † | 1998-12-09 | 2000-06-26 | Amgen, Inc. | Grnf4 a neurotrophic factor |
JP2002051906A (ja) * | 2000-08-11 | 2002-02-19 | Nippon Platec Co Ltd | Ih調理器による加熱を可能にしたアルミ箔材料及びこのアルミ箔材料を用いて成形したアルミ箔材料製食品用容器 |
US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
WO2018191688A2 (en) † | 2017-04-14 | 2018-10-18 | Johnson Controls Techology Company | Thermostat with exhaust fan control for air quality and humidity control |
-
1999
- 1999-07-14 SI SI9931076T patent/SI1640381T1/sl unknown
- 1999-07-14 DE DE69933771T patent/DE69933771T2/de not_active Expired - Lifetime
- 1999-07-14 CZ CZ20010028A patent/CZ303868B6/cs not_active IP Right Cessation
- 1999-07-14 PT PT51124733T patent/PT1640381E/pt unknown
- 1999-07-14 DK DK05112473.3T patent/DK1640381T3/da active
- 1999-07-14 AT AT99938261T patent/ATE343594T1/de active
- 1999-07-14 BR BRPI9912819A patent/BRPI9912819B8/pt unknown
- 1999-07-14 EP EP99938261.7A patent/EP1097167B2/de not_active Expired - Lifetime
- 1999-07-14 ID IDW20010091A patent/ID27024A/id unknown
- 1999-07-14 BR BR9912819-5A patent/BR9912819A/pt not_active IP Right Cessation
- 1999-07-14 EP EP05112473.3A patent/EP1640381B1/de not_active Expired - Lifetime
- 1999-07-14 WO PCT/EP1999/005031 patent/WO2000004050A2/en active IP Right Grant
- 1999-07-14 HU HU0102821A patent/HU226073B1/hu unknown
- 1999-07-14 DK DK99938261T patent/DK1097167T3/da active
- 1999-07-14 PT PT99938261T patent/PT1097167E/pt unknown
- 1999-07-14 TR TR2001/00074T patent/TR200100074T2/xx unknown
- 1999-07-14 KR KR1020067009858A patent/KR100773776B1/ko not_active IP Right Cessation
- 1999-07-14 SK SK14-2001A patent/SK287361B6/sk not_active IP Right Cessation
- 1999-07-14 NZ NZ509723A patent/NZ509723A/en not_active IP Right Cessation
- 1999-07-14 KR KR1020017000494A patent/KR100712223B1/ko not_active IP Right Cessation
- 1999-07-14 CA CA2333910A patent/CA2333910C/en not_active Expired - Lifetime
- 1999-07-14 PL PL348431A patent/PL209952B1/pl unknown
- 1999-07-14 ES ES05112473.3T patent/ES2479067T3/es not_active Expired - Lifetime
- 1999-07-14 IL IL14087799A patent/IL140877A0/xx not_active IP Right Cessation
- 1999-07-14 AU AU52832/99A patent/AU768472B2/en not_active Expired
- 1999-07-14 CN CNB998108847A patent/CN1243770C/zh not_active Expired - Lifetime
- 1999-07-14 ES ES99938261T patent/ES2275349T3/es not_active Expired - Lifetime
- 1999-07-14 JP JP2000560156A patent/JP4469500B2/ja not_active Expired - Lifetime
-
2001
- 2001-01-03 BG BG105107A patent/BG65518B1/bg unknown
- 2001-01-12 NO NO20010212A patent/NO331809B1/no not_active IP Right Cessation
- 2001-01-12 HR HR20010036A patent/HRP20010036B1/xx not_active IP Right Cessation
-
2002
- 2002-09-23 HK HK02106928.2A patent/HK1045528B/zh not_active IP Right Cessation
-
2005
- 2005-03-08 US US11/074,498 patent/US7544788B2/en not_active Expired - Fee Related
-
2006
- 2006-11-24 HK HK06112934.8A patent/HK1092477A1/xx not_active IP Right Cessation
-
2007
- 2007-01-25 CY CY20071100092T patent/CY1105949T1/el unknown
-
2010
- 2010-01-14 JP JP2010006098A patent/JP4624476B2/ja not_active Expired - Lifetime
-
2014
- 2014-07-16 CY CY20141100535T patent/CY1115496T1/el unknown
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