PT1581248E - Modificação do comportamento alimentar e controlo do peso através da oxintomodulina - Google Patents
Modificação do comportamento alimentar e controlo do peso através da oxintomodulina Download PDFInfo
- Publication number
- PT1581248E PT1581248E PT04701379T PT04701379T PT1581248E PT 1581248 E PT1581248 E PT 1581248E PT 04701379 T PT04701379 T PT 04701379T PT 04701379 T PT04701379 T PT 04701379T PT 1581248 E PT1581248 E PT 1581248E
- Authority
- PT
- Portugal
- Prior art keywords
- oxyntomodulin
- modification
- weight control
- feeding behaviour
- compositions
- Prior art date
Links
- 102400000319 Oxyntomodulin Human genes 0.000 title abstract 2
- 101800001388 Oxyntomodulin Proteins 0.000 title abstract 2
- PXZWGQLGAKCNKD-DPNMSELWSA-N molport-023-276-326 Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O)[C@@H](C)O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 PXZWGQLGAKCNKD-DPNMSELWSA-N 0.000 title abstract 2
- 230000004634 feeding behavior Effects 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 238000004260 weight control Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 235000012631 food intake Nutrition 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2271—Neuropeptide Y
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Exchange Systems With Centralized Control (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- External Artificial Organs (AREA)
- Paper (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0300571.7A GB0300571D0 (en) | 2003-01-10 | 2003-01-10 | Modification of feeding behaviour |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1581248E true PT1581248E (pt) | 2011-09-01 |
Family
ID=9950947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT04701379T PT1581248E (pt) | 2003-01-10 | 2004-01-12 | Modificação do comportamento alimentar e controlo do peso através da oxintomodulina |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20060189522A1 (https=) |
| EP (2) | EP2371378A1 (https=) |
| JP (2) | JP5645339B2 (https=) |
| AT (1) | ATE510554T1 (https=) |
| AU (2) | AU2004204369B2 (https=) |
| CA (1) | CA2512939A1 (https=) |
| DK (1) | DK1581248T3 (https=) |
| ES (1) | ES2367113T3 (https=) |
| GB (1) | GB0300571D0 (https=) |
| PT (1) | PT1581248E (https=) |
| SI (1) | SI1581248T1 (https=) |
| WO (1) | WO2004062685A2 (https=) |
Families Citing this family (74)
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|---|---|---|---|---|
| GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| KR100989647B1 (ko) | 2001-09-24 | 2010-10-26 | 오레곤 헬스 앤드 사이언스 유니버시티 | 식습관의 변화 |
| US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| GB0300571D0 (en) * | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| GB0511986D0 (en) * | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| RU2485135C2 (ru) * | 2005-06-13 | 2013-06-20 | Импиэриэл Инноувейшнс Лимитид | Соединения оксинтомодулина (варианты), фармацевтическая композиция на их основе, способы лечения и профилактики ожирения и сопутствующих заболеваний (варианты) и лекарственное средство (варианты) |
| CN101389648B (zh) | 2006-02-22 | 2013-07-17 | 默沙东公司 | 肽胃泌酸调节素衍生物 |
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| TWI428346B (zh) * | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
| HRP20130259T1 (hr) | 2007-04-23 | 2013-04-30 | Intarcia Therapeutics, Inc. | Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe |
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| DK2240155T3 (da) | 2008-02-13 | 2012-09-17 | Intarcia Therapeutics Inc | Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler |
| US8685919B2 (en) | 2008-12-15 | 2014-04-01 | Zealand Pharma A/S | Glucagon analogues |
| KR20110126592A (ko) | 2008-12-15 | 2011-11-23 | 질랜드 파마 에이/에스 | 글루카곤 유사체 |
| WO2010070255A1 (en) | 2008-12-15 | 2010-06-24 | Zealand Pharma A/S | Glucagon analogues |
| JP5635531B2 (ja) | 2008-12-15 | 2014-12-03 | ジーランド ファーマ アクティーゼルスカブ | グルカゴン類似体 |
| AP3329A (en) | 2009-07-13 | 2015-06-30 | Zealand Pharma As | Acylated glucagon analogues |
| SMT201700583T1 (it) | 2009-09-28 | 2018-01-11 | Intarcia Therapeutics Inc | Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario |
| AR079344A1 (es) | 2009-12-22 | 2012-01-18 | Lilly Co Eli | Analogo peptidico de oxintomodulina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar diabetes no insulinodependiente y/u obesidad |
| AR079345A1 (es) | 2009-12-22 | 2012-01-18 | Lilly Co Eli | Analogo peptidico de oxintomodulina |
| UY33462A (es) | 2010-06-23 | 2012-01-31 | Zealand Pharma As | Analogos de glucagon |
| PH12012502472A1 (en) | 2010-06-24 | 2013-03-25 | Zealand Pharma As | Glucagon analogues |
| GB201101459D0 (en) | 2011-01-27 | 2011-03-16 | Imp Innovations Ltd | Novel compounds and thier effects on fedding behaviour |
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| US10166295B2 (en) * | 2011-06-02 | 2019-01-01 | Opko Biologics Ltd. | Pegylated OXM variants |
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| PE20230404A1 (es) | 2011-06-17 | 2023-03-07 | Hanmi Science Co Ltd | Un conjugado que comprende oxintomodulina y un fragmento de inmunoglobulina, y uso del mismo |
| RU2610175C2 (ru) | 2011-09-23 | 2017-02-08 | Ново Нордиск А/С | Новые аналоги глюкагона |
| US10039813B2 (en) | 2012-02-07 | 2018-08-07 | Massachusetts Institute Of Technology | Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness |
| JP6228187B2 (ja) | 2012-05-03 | 2017-11-08 | ジーランド ファーマ アクティーゼルスカブ | Gip−glp−1デュアルアゴニスト化合物及び方法 |
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| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
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| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| KR101993393B1 (ko) * | 2012-11-06 | 2019-10-01 | 한미약품 주식회사 | 옥신토모듈린 유도체를 포함하는 당뇨병 또는 비만성 당뇨병 치료용 조성물 |
| PE20151421A1 (es) | 2012-11-06 | 2015-09-24 | Hanmi Pharm Ind Co Ltd | Formulacion liquida del conjugado de proteina que comprende la oxintomodulina y un fragmento de inmunoglobulina |
| HK1211232A1 (en) | 2012-12-21 | 2016-05-20 | Sanofi | Exendin-4 derivatives as dual glp1/gip or trigonal glp1/gip/glucagon agonists |
| WO2014144231A1 (en) | 2013-03-15 | 2014-09-18 | Massachusetts Institute Of Technology | Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness |
| SI2986313T1 (sl) | 2013-04-18 | 2019-09-30 | Novo Nordisk A/S | Stabilni koagonisti GLP-1 / glukagonskega receptorja z dolgotrajnim učinkom za medicinsko uporabo |
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| US10570184B2 (en) | 2014-06-04 | 2020-02-25 | Novo Nordisk A/S | GLP-1/glucagon receptor co-agonists for medical use |
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-
2003
- 2003-01-10 GB GBGB0300571.7A patent/GB0300571D0/en not_active Ceased
-
2004
- 2004-01-12 EP EP11166784A patent/EP2371378A1/en not_active Withdrawn
- 2004-01-12 US US10/541,526 patent/US20060189522A1/en not_active Abandoned
- 2004-01-12 SI SI200431729T patent/SI1581248T1/sl unknown
- 2004-01-12 WO PCT/GB2004/000017 patent/WO2004062685A2/en not_active Ceased
- 2004-01-12 ES ES04701379T patent/ES2367113T3/es not_active Expired - Lifetime
- 2004-01-12 DK DK04701379.2T patent/DK1581248T3/da active
- 2004-01-12 AU AU2004204369A patent/AU2004204369B2/en not_active Ceased
- 2004-01-12 AT AT04701379T patent/ATE510554T1/de active
- 2004-01-12 PT PT04701379T patent/PT1581248E/pt unknown
- 2004-01-12 EP EP04701379A patent/EP1581248B1/en not_active Revoked
- 2004-01-12 CA CA002512939A patent/CA2512939A1/en not_active Abandoned
- 2004-01-12 JP JP2006500176A patent/JP5645339B2/ja not_active Expired - Fee Related
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2007
- 2007-07-23 US US11/781,773 patent/US7825091B2/en not_active Expired - Fee Related
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2009
- 2009-12-02 AU AU2009243489A patent/AU2009243489B2/en not_active Ceased
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2010
- 2010-09-03 US US12/875,636 patent/US20110021420A1/en not_active Abandoned
- 2010-11-29 JP JP2010264589A patent/JP2011042688A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2367113T3 (es) | 2011-10-28 |
| AU2004204369A1 (en) | 2004-07-29 |
| EP1581248B1 (en) | 2011-05-25 |
| JP2011042688A (ja) | 2011-03-03 |
| HK1080010A1 (en) | 2006-04-21 |
| US20110021420A1 (en) | 2011-01-27 |
| DK1581248T3 (da) | 2011-08-29 |
| AU2004204369B2 (en) | 2009-09-03 |
| AU2009243489A1 (en) | 2009-12-24 |
| ATE510554T1 (de) | 2011-06-15 |
| AU2009243489B2 (en) | 2013-03-14 |
| WO2004062685A2 (en) | 2004-07-29 |
| US20060189522A1 (en) | 2006-08-24 |
| US20080064636A1 (en) | 2008-03-13 |
| GB0300571D0 (en) | 2003-02-12 |
| EP1581248A2 (en) | 2005-10-05 |
| EP2371378A1 (en) | 2011-10-05 |
| SI1581248T1 (sl) | 2011-10-28 |
| AU2004204369A8 (en) | 2004-07-29 |
| US7825091B2 (en) | 2010-11-02 |
| JP2006515351A (ja) | 2006-05-25 |
| WO2004062685A3 (en) | 2004-09-10 |
| JP5645339B2 (ja) | 2014-12-24 |
| CA2512939A1 (en) | 2004-07-29 |
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