PT1392287E - Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito - Google Patents
Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito Download PDFInfo
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- PT1392287E PT1392287E PT02774113T PT02774113T PT1392287E PT 1392287 E PT1392287 E PT 1392287E PT 02774113 T PT02774113 T PT 02774113T PT 02774113 T PT02774113 T PT 02774113T PT 1392287 E PT1392287 E PT 1392287E
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| DE60216300T2 (de) * | 2001-09-21 | 2007-06-28 | Schering Corp. | Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption |
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| CN1756756A (zh) | 2003-03-07 | 2006-04-05 | 先灵公司 | 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途 |
| ES2311806T3 (es) * | 2003-03-07 | 2009-02-16 | Schering Corporation | Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| US7459442B2 (en) * | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
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| ATE437641T1 (de) | 2003-05-15 | 2009-08-15 | Roskamp Res Llc | Verfahren zur herstellung von medikamenten zur verringerung der amyloid-abscheidung, amyloid- neurotoxizität und mikrogliosis |
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| ATE485267T1 (de) | 2003-12-23 | 2010-11-15 | Astrazeneca Ab | Diphenylazetidinonderivate mit die cholesterinabsorption hemmender wirkung |
| US7838552B2 (en) | 2004-06-04 | 2010-11-23 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| US7803838B2 (en) * | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
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| GB0423356D0 (en) * | 2004-10-21 | 2004-11-24 | Merck Sharp & Dohme | Therapeutic agents |
| SA06270191B1 (ar) | 2005-06-22 | 2010-03-29 | استرازينيكا ايه بي | مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم |
| CA2613239A1 (en) * | 2005-06-22 | 2006-12-28 | Manne Satyanarayana Reddy | Improved process for the preparation of ezetimibe |
| US20070049748A1 (en) * | 2005-08-26 | 2007-03-01 | Uppala Venkata Bhaskara R | Preparation of ezetimibe |
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| BRPI0806371A2 (pt) * | 2007-01-22 | 2011-09-13 | Gtx Inc | agentes ligação de receptor nuclear |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| GB0708507D0 (en) * | 2007-05-02 | 2007-06-13 | Queen Mary & Westfield College | Substituted phosphonates and their use |
| RU2490014C2 (ru) | 2007-10-05 | 2013-08-20 | Альцгеймер'С Инститьют Оф Америка, Инк. | Способ уменьшения отложения амилоида, амилоидной нейротоксичности и микроглиоза с помощью (-)-энантиомера нилвадипина |
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| US20090221554A1 (en) * | 2008-02-28 | 2009-09-03 | Zenyaku Kogyo Kabushiki Kaisha | Method of treating cognitive impairment |
| US20130267533A1 (en) * | 2012-04-04 | 2013-10-10 | Fabre-Kramer Pharmaceuticals, Inc. | 5ht1a agonists for treatment of high cholesterol |
| CA3012415C (en) * | 2016-02-11 | 2024-03-12 | Sigmathera Sas | Igmesine for use in the treatment of neurodegenerative diseases |
| US11135180B2 (en) * | 2016-03-15 | 2021-10-05 | Rush University Medical Center | Composition and methods for stimulating clearance of amyloid-beta protein |
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| US3692895A (en) * | 1970-09-08 | 1972-09-19 | Norman A Nelson | Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria |
| DE2230383C3 (de) * | 1971-10-01 | 1981-12-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Phenoxyalkylcarbonsäurederivate und Verfahren zur Herstellung derselben |
| US4148923A (en) * | 1972-05-31 | 1979-04-10 | Synthelabo | 1-(3'-Trifluoromethylthiophenyl)-2-ethylaminopropane pharmaceutical composition and method for treating obesity |
| US3948973A (en) * | 1972-08-29 | 1976-04-06 | Sterling Drug Inc. | Halocyclopropyl substituted phenoxyalkanoic acids |
| US4626549A (en) * | 1974-01-10 | 1986-12-02 | Eli Lilly And Company | Treatment of obesity with aryloxyphenylpropylamines |
| US4179515A (en) * | 1975-02-12 | 1979-12-18 | Orchimed S. A. | Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition |
| US4235896A (en) * | 1975-02-12 | 1980-11-25 | Orchimed S.A. | Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same |
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| US4075000A (en) * | 1975-05-27 | 1978-02-21 | Eli Lilly And Company | Herbicidal use of 4-amino-3,3-dimethyl-1-phenyl-2-azetidinones |
| US4472309A (en) * | 1975-10-06 | 1984-09-18 | Fujisawa Pharmaceutical Co., Ltd. | 2-Azetidinone compounds and processes for preparation thereof |
| US4304718A (en) * | 1975-10-06 | 1981-12-08 | Fujisawa Pharmaceutical Co., Ltd. | 2-Azetidinone compounds and processes for preparation thereof |
| US4576753A (en) * | 1975-10-06 | 1986-03-18 | Fujisawa Pharmaceutical Co., Ltd. | Azetidinone compounds and processes for preparation thereof |
| US4166907A (en) * | 1976-11-01 | 1979-09-04 | E. R. Squibb & Sons, Inc. | 3,3-Dichloro-2-azetidinone derivatives having antiinflammatory activity |
| US4144232A (en) * | 1976-12-23 | 1979-03-13 | Eli Lilly And Company | Substituted azetidin-2-one antibiotics |
| FR2403078A1 (fr) * | 1977-09-19 | 1979-04-13 | Lafon Labor | Nouveau procede de preparation de formes pharmaceutiques, cosmetiques ou de diagnostic |
| IT1157365B (it) * | 1977-10-24 | 1987-02-11 | Sandoz Ag | Medicamenti per trattare l'obesita' o ridurre il peso del corpo |
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-
2002
- 2002-05-22 PT PT02774113T patent/PT1392287E/pt unknown
- 2002-05-22 CA CA002447884A patent/CA2447884A1/en not_active Abandoned
- 2002-05-22 AU AU2002308778A patent/AU2002308778A1/en not_active Abandoned
- 2002-05-22 DE DE60216275T patent/DE60216275T2/de not_active Expired - Fee Related
- 2002-05-22 JP JP2002592925A patent/JP2004532868A/ja active Pending
- 2002-05-22 WO PCT/US2002/016306 patent/WO2002096415A2/en not_active Ceased
- 2002-05-22 AR ARP020101893A patent/AR038956A1/es unknown
- 2002-05-22 MX MXPA03010843A patent/MXPA03010843A/es active IP Right Grant
- 2002-05-22 EP EP02774113A patent/EP1392287B8/en not_active Expired - Lifetime
- 2002-05-22 ES ES02774113T patent/ES2275007T3/es not_active Expired - Lifetime
- 2002-05-22 DK DK02774113T patent/DK1392287T3/da active
- 2002-05-22 AT AT02774113T patent/ATE345792T1/de not_active IP Right Cessation
- 2002-05-22 US US10/154,106 patent/US20030013699A1/en not_active Abandoned
-
2007
- 2007-01-15 CY CY20071100048T patent/CY1105922T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1392287A2 (en) | 2004-03-03 |
| DE60216275T2 (de) | 2007-06-21 |
| DK1392287T3 (da) | 2007-03-19 |
| CA2447884A1 (en) | 2002-12-05 |
| CY1105922T1 (el) | 2011-04-06 |
| WO2002096415A2 (en) | 2002-12-05 |
| EP1392287B8 (en) | 2007-01-10 |
| WO2002096415A3 (en) | 2003-01-16 |
| ES2275007T3 (es) | 2007-06-01 |
| ATE345792T1 (de) | 2006-12-15 |
| US20030013699A1 (en) | 2003-01-16 |
| AU2002308778A1 (en) | 2002-12-09 |
| MXPA03010843A (es) | 2004-02-17 |
| EP1392287B1 (en) | 2006-11-22 |
| AR038956A1 (es) | 2005-02-02 |
| JP2004532868A (ja) | 2004-10-28 |
| DE60216275D1 (de) | 2007-01-04 |
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