PT1384478E - Composi??es de antibi?tico que cont?m moxifloxacina para o tratamento dos olhos - Google Patents

Composi??es de antibi?tico que cont?m moxifloxacina para o tratamento dos olhos Download PDF

Info

Publication number
PT1384478E
PT1384478E PT03020587T PT03020587T PT1384478E PT 1384478 E PT1384478 E PT 1384478E PT 03020587 T PT03020587 T PT 03020587T PT 03020587 T PT03020587 T PT 03020587T PT 1384478 E PT1384478 E PT 1384478E
Authority
PT
Portugal
Prior art keywords
antibytic
compositions containing
eye treatment
containing moxifloxacin
moxifloxacin
Prior art date
Application number
PT03020587T
Other languages
English (en)
Portuguese (pt)
Inventor
John M Yanni
Gerald Cagle
Robert L Abshire
David W Stromann
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1384478(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of PT1384478E publication Critical patent/PT1384478E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT03020587T 1998-09-30 1999-09-29 Composi??es de antibi?tico que cont?m moxifloxacina para o tratamento dos olhos PT1384478E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10250498P 1998-09-30 1998-09-30
US10250698P 1998-09-30 1998-09-30

Publications (1)

Publication Number Publication Date
PT1384478E true PT1384478E (pt) 2011-05-12

Family

ID=26799441

Family Applications (5)

Application Number Title Priority Date Filing Date
PT101786572T PT2301541E (pt) 1998-09-30 1999-09-29 Composições de antibiótico para o tratamento dos olhos
PT99956504T PT1117401E (pt) 1998-09-30 1999-09-29 Composicoes antibioticas para o tratamento do olho
PT141763664T PT2796138T (pt) 1998-09-30 1999-09-29 Composições antibióticas para tratamento da conjuntivite
PT101764124T PT2269602E (pt) 1998-09-30 1999-09-29 Composições de antibiótico para o tratamento do ouvido
PT03020587T PT1384478E (pt) 1998-09-30 1999-09-29 Composi??es de antibi?tico que cont?m moxifloxacina para o tratamento dos olhos

Family Applications Before (4)

Application Number Title Priority Date Filing Date
PT101786572T PT2301541E (pt) 1998-09-30 1999-09-29 Composições de antibiótico para o tratamento dos olhos
PT99956504T PT1117401E (pt) 1998-09-30 1999-09-29 Composicoes antibioticas para o tratamento do olho
PT141763664T PT2796138T (pt) 1998-09-30 1999-09-29 Composições antibióticas para tratamento da conjuntivite
PT101764124T PT2269602E (pt) 1998-09-30 1999-09-29 Composições de antibiótico para o tratamento do ouvido

Country Status (18)

Country Link
EP (5) EP2269602B1 (Direct)
JP (5) JP2002525317A (Direct)
KR (1) KR101463243B1 (Direct)
CN (2) CN1184968C (Direct)
AR (2) AR020661A1 (Direct)
AT (2) ATE254458T1 (Direct)
AU (1) AU762827B2 (Direct)
BR (1) BRPI9914151B1 (Direct)
CA (3) CA2342211C (Direct)
CY (3) CY1111404T1 (Direct)
DE (2) DE69912972T2 (Direct)
DK (5) DK2301541T3 (Direct)
ES (4) ES2602956T3 (Direct)
HK (1) HK1038691B (Direct)
PT (5) PT2301541E (Direct)
TR (2) TR200704370T2 (Direct)
TW (1) TWI222361B (Direct)
WO (1) WO2000018386A2 (Direct)

Families Citing this family (37)

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US6509327B1 (en) * 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
DE19937115A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
WO2001022936A1 (en) 1999-09-24 2001-04-05 Alcon Universal Ltd. Topical suspension formulations containing ciprofloxacin and dexamethasone
DE19962470A1 (de) 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
AU2001261748A1 (en) * 2000-05-19 2001-12-03 Alcon Laboratories Inc. Antibiotic compositions for treatment of the eye, ear and nose
US6462033B2 (en) 2000-07-26 2002-10-08 Alcon Universal Ltd. Process for manufacturing compositions containing ciprofloxacin and hydrocortisone
AU2002214308A1 (en) * 2000-11-16 2002-05-27 Wakamoto Pharmaceutical Co., Ltd. Antibacterial gel eye drops
AU2002228660A1 (en) 2000-12-20 2002-07-01 Alcon, Inc Use of amidoamines to treat or prevent acanthamoeba and fungal infections
AU2002226926A1 (en) * 2000-12-20 2002-07-01 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
ATE313328T1 (de) 2001-09-21 2006-01-15 Alcon Inc Verfahren zur behandlung von mittelohrinfektionen
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
ES2424676T3 (es) 2003-09-10 2013-10-07 Kyorin Pharmaceutical Co., Ltd. Derivado de ácido 7-(3-ciclopropilaminometil-1-pirrolidinil 4-sustituido)quinoloncarboxílico
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
AU2005282571A1 (en) * 2004-09-03 2006-03-16 Piedmont Pharmaceuticals, Llc Methods for transmembrane treatment and prevention of otitis media
DE102005055385A1 (de) * 2004-12-09 2006-06-14 Bayer Healthcare Ag Arzneimittel zur hygienischen Applikation im Ohr
MX2007005980A (es) * 2004-12-10 2007-07-10 Alcon Inc Composiciones para el tratamiento de infecciones oticas.
CN101317847B (zh) * 2007-06-06 2010-10-13 深圳市瑞谷医药技术有限公司 一种眼用或耳鼻用药物组合物及其用途
TWI544934B (zh) * 2008-06-09 2016-08-11 愛爾康研究有限公司 含有氟喹諾酮抗生素藥物之經改良藥學組成物
CN105687111A (zh) * 2009-07-02 2016-06-22 爱尔康研究有限公司 用于治疗眼、耳或鼻感染的包含非那沙星的组合物和方法
RU2016101214A (ru) * 2010-01-07 2018-11-21 Риджентс Оф Дзе Юниверсити Оф Миннесота Способы и композиции для нанесения моксифлоксацина в ухо
RU2014127492A (ru) 2011-12-06 2016-02-10 Алькон Рисерч, Лтд. Композиции целлюлозного геля с улучшенной стабильностью вязкости
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
US9504691B2 (en) * 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
CN104224802B (zh) * 2014-09-19 2017-12-12 南京优科生物医药研究有限公司 一种盐酸莫西沙星滴耳剂及其制备方法
RU2595837C2 (ru) * 2014-09-29 2016-08-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазных капель
WO2017073708A1 (ja) * 2015-10-29 2017-05-04 テイカ製薬株式会社 外用剤
US12042500B2 (en) * 2018-04-03 2024-07-23 Hyderabad Eye Research Foundation Mucoadhesive drug delivery system for ocular administration of fluoroquinolone antibiotics
IT201900005280A1 (it) * 2019-04-05 2020-10-05 Ntc S R L Composizione otologica
AU2021289250A1 (en) * 2020-06-10 2023-02-16 Ocular Science, Inc. Compositions and uses in method for post-operative ocular care
CN116270662A (zh) * 2021-12-03 2023-06-23 苏州欧康维视生物科技有限公司 盐酸莫西沙星地塞米松磷酸钠滴眼液
KR102656260B1 (ko) 2022-10-14 2024-04-09 주식회사태준제약 목시플록사신을 포함하는 안과용 조성물

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CA1325382C (en) * 1988-01-27 1993-12-21 Takahiro Ogawa Locally administrable therapeutic composition for inflammatory disease
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JPH03109236A (ja) * 1989-09-22 1991-05-09 Hoya Corp 半導体超微粒子分散ガラスの製造方法
TW209865B (Direct) * 1992-01-10 1993-07-21 Bayer Ag
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DE4424369A1 (de) * 1994-07-11 1996-01-18 Bayer Ag Pyrido[3,2,1.i,j][3,1]benzoxazinderivate
JPH0892241A (ja) * 1994-09-22 1996-04-09 Ss Pharmaceut Co Ltd ５−ヒドラジノキノロンカルボン酸誘導体及びこれを有効成分とする抗菌剤
US5631287A (en) 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
ZA964653B (en) * 1995-06-06 1996-12-12 Bayer Ag Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions
JP3290914B2 (ja) * 1997-03-17 2002-06-10 参天製薬株式会社 眼組織におけるキノロン系抗菌剤の定量装置
CN1178659C (zh) * 1997-09-25 2004-12-08 拜尔公司 控释活性化合物的药物制剂
WO2000016736A1 (en) 1998-09-23 2000-03-30 Unilever N.V. Oral care compositions
AR020661A1 (es) 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US20020001617A1 (en) * 2000-05-26 2002-01-03 Chang-Hyun Lee Rapidly disintegrating tablet and process for the manufacture thereof

Also Published As

Publication number Publication date
HK1038691A1 (en) 2002-03-28
PT2269602E (pt) 2014-12-29
BRPI9914151B1 (pt) 2017-10-03
HK1059572A1 (en) 2004-07-09
CN1320035A (zh) 2001-10-31
CY1115759T1 (el) 2017-01-25
EP1117401A2 (en) 2001-07-25
HK1150756A1 (en) 2012-01-13
EP2796138B1 (en) 2016-08-17
DK1117401T3 (da) 2004-02-23
CN1184968C (zh) 2005-01-19
EP1117401B1 (en) 2003-11-19
WO2000018386A3 (en) 2000-06-08
WO2000018386A2 (en) 2000-04-06
JP5563041B2 (ja) 2014-07-30
CA2342211C (en) 2009-05-26
AR081393A2 (es) 2012-08-29
AR020661A1 (es) 2002-05-22
CY1115916T1 (el) 2017-01-25
EP1384478B1 (en) 2011-03-16
EP2796138A1 (en) 2014-10-29
PT1117401E (pt) 2004-03-31
EP2269602B1 (en) 2014-11-19
DE69912972D1 (de) 2003-12-24
EP2301541B1 (en) 2014-08-20
DK2269602T3 (en) 2014-12-15
ES2519190T3 (es) 2014-11-06
JP2009007375A (ja) 2009-01-15
EP2269602A1 (en) 2011-01-05
ES2207307T3 (es) 2004-05-16
CY1111404T1 (el) 2015-08-05
DK1384478T3 (da) 2011-05-23
CA2342211A1 (en) 2000-04-06
HK1038691B (en) 2004-04-23
DE69912972T2 (de) 2004-04-22
KR20010075138A (ko) 2001-08-09
JP2013018799A (ja) 2013-01-31
CN1650863A (zh) 2005-08-10
DK2301541T3 (da) 2014-09-01
BRPI9914151B8 (Direct) 2021-05-25
EP1384478A1 (en) 2004-01-28
DE69943287D1 (de) 2011-04-28
HK1150769A1 (en) 2012-01-13
ES2526521T3 (es) 2015-01-13
AU1310100A (en) 2000-04-17
AU762827B2 (en) 2003-07-03
JP2012067141A (ja) 2012-04-05
CA2659064A1 (en) 2000-04-06
CN100374114C (zh) 2008-03-12
PT2301541E (pt) 2014-10-29
TR200704370T2 (tr) 2007-11-21
TWI222361B (en) 2004-10-21
PT2796138T (pt) 2016-09-22
JP2014144982A (ja) 2014-08-14
CA2774207A1 (en) 2000-04-06
DK2796138T3 (en) 2016-12-05
JP2002525317A (ja) 2002-08-13
BR9914151A (pt) 2001-06-26
ATE501732T1 (de) 2011-04-15
TR200100883T2 (tr) 2001-10-22
KR101463243B1 (ko) 2014-12-17
EP2301541A1 (en) 2011-03-30
ES2602956T3 (es) 2017-02-23
ATE254458T1 (de) 2003-12-15

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