PT1309607E - Processo para a preparacao de antagonistas lhrh - Google Patents
Processo para a preparacao de antagonistas lhrhInfo
- Publication number
- PT1309607E PT1309607E PT01978273T PT01978273T PT1309607E PT 1309607 E PT1309607 E PT 1309607E PT 01978273 T PT01978273 T PT 01978273T PT 01978273 T PT01978273 T PT 01978273T PT 1309607 E PT1309607 E PT 1309607E
- Authority
- PT
- Portugal
- Prior art keywords
- peptide
- basic
- ion exchanger
- preparation
- diluent
- Prior art date
Links
- 229940124041 Luteinizing hormone releasing hormone (LHRH) antagonist Drugs 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000003085 diluting agent Substances 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10040700A DE10040700A1 (de) | 2000-08-17 | 2000-08-17 | Salze von biologisch aktiven Peptiden, ihre Herstellung und Verwendung |
| CA002355573A CA2355573A1 (en) | 2000-08-17 | 2001-08-22 | Method for the synthesis of peptide salts, their use and the pharmaceutical preparations, containing peptide salts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1309607E true PT1309607E (pt) | 2005-02-28 |
Family
ID=27805895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT01978273T PT1309607E (pt) | 2000-08-17 | 2001-08-09 | Processo para a preparacao de antagonistas lhrh |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6780972B2 (pt) |
| EP (1) | EP1309607B1 (pt) |
| JP (1) | JP2004506647A (pt) |
| CN (1) | CN1187369C (pt) |
| AR (1) | AR030371A1 (pt) |
| AT (1) | ATE280779T1 (pt) |
| AU (2) | AU2002210439B2 (pt) |
| BG (1) | BG107612A (pt) |
| BR (1) | BR0113296A (pt) |
| CA (1) | CA2355573A1 (pt) |
| CZ (1) | CZ2003688A3 (pt) |
| DE (2) | DE10040700A1 (pt) |
| DK (1) | DK1309607T3 (pt) |
| EE (1) | EE200300065A (pt) |
| ES (1) | ES2230371T3 (pt) |
| HK (1) | HK1058366A1 (pt) |
| HU (1) | HUP0300738A3 (pt) |
| IL (1) | IL154150A0 (pt) |
| MX (1) | MXPA03001448A (pt) |
| NO (1) | NO20030618L (pt) |
| NZ (1) | NZ524023A (pt) |
| PL (1) | PL204496B1 (pt) |
| PT (1) | PT1309607E (pt) |
| RU (1) | RU2266296C2 (pt) |
| SI (1) | SI1309607T1 (pt) |
| SK (1) | SK3032003A3 (pt) |
| TW (1) | TWI236910B (pt) |
| UA (1) | UA74005C2 (pt) |
| WO (1) | WO2002014347A2 (pt) |
| ZA (1) | ZA200300777B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
| US7098305B2 (en) * | 2001-09-06 | 2006-08-29 | Ardana Bioscience Limited | Sustained release of microcrystalline peptide suspensions |
| EP1674082A1 (de) * | 2004-12-22 | 2006-06-28 | Zentaris GmbH | Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel |
| RU2525661C2 (ru) * | 2012-11-15 | 2014-08-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" Российской академии медицинских наук (ФГБУ "НИИВС им. И.И. Мечникова" РАМН) | Способ получения высокотитражной антимикробной сыворотки для оценки антигенной активности противостафилококковых вакцин |
| CN107056894B (zh) * | 2017-05-26 | 2021-07-20 | 济南康和医药科技有限公司 | 一种片段法固相合成醋酸加尼瑞克的方法 |
| EP3590526A1 (en) * | 2018-07-05 | 2020-01-08 | Antev Limited | A lyophilization process and a teverelix-tfa lyophilizate obtained thereby |
| CN114249800B (zh) * | 2020-09-22 | 2024-07-26 | 深圳市星银医药有限公司 | 一种双羟萘酸多肽药物的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431635A (en) * | 1979-06-13 | 1984-02-14 | Coy David Howard | LH-RH Antagonists |
| ATE8988T1 (de) * | 1980-06-02 | 1984-09-15 | Andrew Victor Schally | Lh-rh antagonisten. |
| US4800191A (en) * | 1987-07-17 | 1989-01-24 | Schally Andrew Victor | LHRH antagonists |
| DE4305225A1 (de) * | 1993-02-19 | 1994-08-25 | Asta Medica Ag | Neues Herstellverfahren für Cetrorelix Lyophilisat |
| EP0626170A3 (en) * | 1993-05-10 | 1996-03-27 | Sandoz Ltd | Stabilization of pharmacoligically active compounds in controlled release compositions. |
| CA2178592C (en) * | 1993-12-09 | 2009-07-28 | Jurgen Engel | Long-acting injection suspensions and a process for their preparation |
| DE4342092B4 (de) * | 1993-12-09 | 2007-01-11 | Zentaris Gmbh | Langwirkende Injektionssuspension und Verfahren zur Herstellung |
| US6054432A (en) * | 1996-09-12 | 2000-04-25 | Asta Medica Aktiengesellschaft | Means for treating prostate hypertrophy and prostate cancer |
| NZ505651A (en) * | 1998-01-16 | 2003-08-29 | Takeda Chemical Industries Ltd | Sustained release composition comprising biologically active substance, hydroxynaphthoic acid and biodegradable polymer |
-
2000
- 2000-08-17 DE DE10040700A patent/DE10040700A1/de not_active Withdrawn
-
2001
- 2001-08-09 NZ NZ524023A patent/NZ524023A/en unknown
- 2001-08-09 ES ES01978273T patent/ES2230371T3/es not_active Expired - Lifetime
- 2001-08-09 EE EEP200300065A patent/EE200300065A/xx unknown
- 2001-08-09 JP JP2002519484A patent/JP2004506647A/ja active Pending
- 2001-08-09 WO PCT/EP2001/009219 patent/WO2002014347A2/de active IP Right Grant
- 2001-08-09 AU AU2002210439A patent/AU2002210439B2/en not_active Ceased
- 2001-08-09 AU AU1043902A patent/AU1043902A/xx active Pending
- 2001-08-09 PL PL359495A patent/PL204496B1/pl not_active IP Right Cessation
- 2001-08-09 RU RU2003107560/04A patent/RU2266296C2/ru not_active IP Right Cessation
- 2001-08-09 IL IL15415001A patent/IL154150A0/xx not_active IP Right Cessation
- 2001-08-09 AT AT01978273T patent/ATE280779T1/de not_active IP Right Cessation
- 2001-08-09 SK SK303-2003A patent/SK3032003A3/sk not_active Application Discontinuation
- 2001-08-09 DE DE50104316T patent/DE50104316D1/de not_active Expired - Lifetime
- 2001-08-09 PT PT01978273T patent/PT1309607E/pt unknown
- 2001-08-09 BR BR0113296-2A patent/BR0113296A/pt not_active IP Right Cessation
- 2001-08-09 SI SI200130237T patent/SI1309607T1/xx unknown
- 2001-08-09 HU HU0300738A patent/HUP0300738A3/hu unknown
- 2001-08-09 DK DK01978273T patent/DK1309607T3/da active
- 2001-08-09 CZ CZ2003688A patent/CZ2003688A3/cs unknown
- 2001-08-09 EP EP01978273A patent/EP1309607B1/de not_active Expired - Lifetime
- 2001-08-09 CN CNB018142192A patent/CN1187369C/zh not_active Expired - Fee Related
- 2001-08-09 MX MXPA03001448A patent/MXPA03001448A/es active IP Right Grant
- 2001-08-16 AR ARP010103935A patent/AR030371A1/es active IP Right Grant
- 2001-08-17 TW TW090120293A patent/TWI236910B/zh active
- 2001-08-22 CA CA002355573A patent/CA2355573A1/en not_active Abandoned
- 2001-08-24 US US09/939,532 patent/US6780972B2/en not_active Expired - Fee Related
- 2001-09-08 UA UA2003032260A patent/UA74005C2/uk unknown
-
2003
- 2003-01-29 ZA ZA200300777A patent/ZA200300777B/xx unknown
- 2003-02-07 NO NO20030618A patent/NO20030618L/no unknown
- 2003-03-06 BG BG107612A patent/BG107612A/bg unknown
-
2004
- 2004-02-13 HK HK04101030A patent/HK1058366A1/xx not_active IP Right Cessation
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